Analysis of information sources in references of the Wikipedia article "Major depressive disorder" in English language version.
Despite advances in our understanding of the neuro-biology of MDD, no established mechanism can explain all aspects of the disease.
Depression is highly heritable, as youths with a parent with a history of depression are approximately 4 times as likely to develop the disorder as youths who do not have a parent with depression.
Higher levels of CRP have been consistently found ... often preceding the onset of illness ... suggesting that inflammation could be a cause rather than simply a consequence of the illness ...
Half of all completed suicides are related to depressive and other mood disorders
{{cite book}}: CS1 maint: DOI inactive as of July 2025 (link)Despite advances in our understanding of the neuro-biology of MDD, no established mechanism can explain all aspects of the disease.
Despite advances in our understanding of the neuro-biology of MDD, no established mechanism can explain all aspects of the disease.
Higher levels of CRP have been consistently found ... often preceding the onset of illness ... suggesting that inflammation could be a cause rather than simply a consequence of the illness ...
Half of all completed suicides are related to depressive and other mood disorders
Higher levels of CRP have been consistently found ... often preceding the onset of illness ... suggesting that inflammation could be a cause rather than simply a consequence of the illness ...
Half of all completed suicides are related to depressive and other mood disorders
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) features the most current text updates based on scientific literature with contributions from more than 200 subject matter experts.
{{cite book}}: CS1 maint: DOI inactive as of July 2025 (link)Despite advances in our understanding of the neuro-biology of MDD, no established mechanism can explain all aspects of the disease.
... the latest version of the ICD, ICD-11, was adopted by the 72nd World Health Assembly in 2019 and came into effect on 1st January 2022.
Although there is no single unifying theory, several theories have emerged over the last century that attempt to account for the various clinical, psychological, and biologic findings in depression.
A number of risk factors for depression are known or suspected, but only in rare cases is the link to disease strong.
Depression is highly heritable, as youths with a parent with a history of depression are approximately 4 times as likely to develop the disorder as youths who do not have a parent with depression.
Thus it appears that bipolar disorder is more strongly influenced by genetic factors than is major depressive disorder.