Massive parallel sequencing (English Wikipedia)

US 5641658, Adams CP, Kron SJ, "Method for performing amplification of nucleic acid with two primers bound to a single solid support", published 1997-06-24, assigned to Mosaic Technologies Inc. and Whitehead Institute for Biomedical Research
EP 0972081, Farinelli L, Kawashima E, Mayer P ), "Method of nucleic acid amplification", published 2007-06-13, assigned to Solexa Ltd.
EP 0975802, Kawashima E, Farinellit L, Mayer P, "Method of nucleic acid sequencing", published 2004-06-23
US patent 7790869, Ju J, Li Z, Edwards JR, Itagaki Y, "Massive parallel method for decoding DNA and RNA", published 2010-09-07, assigned to The Trustees of Columbia University in the City of New York
US patent 6485944, Church GM, Mitra R, "Replica amplification of nucleic acid arrays", published 2002-11-26, assigned to President and Fellows of Harvard College
US 9624538, Church GM, Porreca GJ, Shendure J, Rosenbaum AM, "Nanogrid rolling circle DNA sequencing", published 2017-04-18, assigned to President and Fellows of Harvard College
US patent 8445194, Drmanac R, Callow MJ, Drmanac S, Hauser BK, Yeung G, "Single molecule arrays for genetic and chemical analysis", published 2013-05-21, assigned to Callida Genomics Inc.
US 6833246, Balasubramanian S, "Polynucleotide sequencing", published 2004-12-21, assigned to Solexa Ltd.

flxlexblog.wordpress.com (Global: low place; English: low place)

Nederbragt L (2013-07-05). "De novo bacterial genome assembly: a solved problem?".

genome.gov (Global: 9,308^th place; English: 8,899^th place)

"Program Announcement Concept: Technology Development for the $1000 Genome". Archived from the original on March 1, 2025. Retrieved April 6, 2026. {{cite web}}: Check date values in: |access-date= (help)
"2008 Release: NHGRI Seeks DNA Sequencing Technologies Fit for Routine Laboratory and Medical Use". Genome.gov. Retrieved 2012-08-05.

genomeweb.com (Global: low place; English: low place)

"Following Roche's Decision to Shut Down 454, Customers Make Plans to Move to Other Platforms". October 22, 2013.
Monica Heger (March 5, 2013). "PacBio Users Report Progress in Long Reads for Plant Genome Assembly, Tricky Regions of Human Genome".
"PacBio Launches Higher-Throughput, Lower-Cost Single-Molecule Sequencing System". October 2015.

globenewswire.com (Global: 2,614^th place; English: 1,549^th place)

Inc, Pacific Biosciences of California (October 3, 2013). "Pacific Biosciences Introduces New Chemistry With Longer Read Lengths to Detect Novel Features in DNA Sequence and Advance Genome Studies of Large Organisms". GlobeNewswire News Room (Press release). {{cite press release}}: |last= has generic name (help)

harvard.edu (Global: 18^th place; English: 17^th place)

ui.adsabs.harvard.edu

Mardis, E. (2011). "A decade's perspective on DNA sequencing technology". Nature. 470 (7333): 198–203. Bibcode:2011Natur.470..198M. doi:10.1038/nature09796. PMID 21307932.
Margulies M, Egholm M, Altman W, et al. (2005). "Genome sequencing in microfabricated high-density picolitre reactors". Nature. 437 (7057): 376–380. Bibcode:2005Natur.437..376M. doi:10.1038/nature03959. PMC 1464427. PMID 16056220.
Bentley D, Balasubramanian S, Swerdlow H, et al. (2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
Check Hayden, E. (2012). "Roche chases stake in medical sequencing". Nature. 484 (7393): 152. Bibcode:2012Natur.484..152C. doi:10.1038/484152a. PMID 22498604.
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, et al. (November 2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, et al. (January 2010). "Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays". Science. 327 (5961): 78–81. Bibcode:2010Sci...327...78D. doi:10.1126/science.1181498. PMID 19892942. S2CID 17309571.
Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, Rosenbaum AM, et al. (September 2005). "Accurate multiplex polony sequencing of an evolved bacterial genome". Science. 309 (5741): 1728–1732. Bibcode:2005Sci...309.1728S. doi:10.1126/science.1117389. PMID 16081699. S2CID 11405973.
Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, et al. (July 2012). "Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells". Nature. 487 (7406): 190–195. Bibcode:2012Natur.487..190P. doi:10.1038/nature11236. PMC 3397394. PMID 22785314.
Dressman D, Yan H, Traverso G, Kinzler KW, Vogelstein B (July 2003). "Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations". Proceedings of the National Academy of Sciences of the United States of America. 100 (15): 8817–8822. Bibcode:2003PNAS..100.8817D. doi:10.1073/pnas.1133470100. PMC 166396. PMID 12857956.

helicosbio.com (Global: low place; English: low place)

"True Single Molecule Sequencing (tSMS™): Helicos BioSciences". Helicosbio.com. Archived from the original on 2012-03-11. Retrieved 2012-08-05.

illumina.com (Global: low place; English: low place)

systems.illumina.com

"Specifications for HiSeq 2500". Archived from the original on 2014-12-06. Retrieved 2014-11-06.

illumina.com

"Assay Technology". Illumina. Archived from the original on 2012-08-26. Retrieved 2012-08-05.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Nyren, P.; Pettersson, B.; Uhlen, M. (January 1993). "Solid Phase DNA Minisequencing by an Enzymatic Luminometric Inorganic Pyrophosphate Detection Assay". Analytical Biochemistry. 208 (1): 171–175. doi:10.1006/abio.1993.1024. PMID 8382019.
Ronaghi M, Karamohamed S, Pettersson B, Uhlén M, Nyrén P (November 1996). "Real-time DNA sequencing using detection of pyrophosphate release". Analytical Biochemistry. 242 (1): 84–89. doi:10.1006/abio.1996.0432. PMID 8923969.
Voelkerding KV, Dames SA, Durtschi JD (April 2009). "Next-generation sequencing: from basic research to diagnostics". Clinical Chemistry. 55 (4): 641–658. doi:10.1373/clinchem.2008.112789. PMID 19246620.
Ballard D, Winkler-Galicki J, Wesoły J (July 2020). "Massive parallel sequencing in forensics: advantages, issues, technicalities, and prospects". International Journal of Legal Medicine. 134 (4): 1291–1303. doi:10.1007/s00414-020-02294-0. PMC 7295846. PMID 32451905.
Giani AM, Gallo GR, Gianfranceschi L, Formenti G (2020). "Long walk to genomics: History and current approaches to genome sequencing and assembly". Computational and Structural Biotechnology Journal. 100: 9–19. doi:10.1016/j.csbj.2019.11.002. PMC 6926122. PMID 31890139.
Mardis, E. (2011). "A decade's perspective on DNA sequencing technology". Nature. 470 (7333): 198–203. Bibcode:2011Natur.470..198M. doi:10.1038/nature09796. PMID 21307932.
Margulies M, Egholm M, Altman W, et al. (2005). "Genome sequencing in microfabricated high-density picolitre reactors". Nature. 437 (7057): 376–380. Bibcode:2005Natur.437..376M. doi:10.1038/nature03959. PMC 1464427. PMID 16056220.
Heather, James M.; Chain, Benjamin (2016). "The sequence of sequencers: The history of sequencing DNA". Genomics. 107 (1): 1–8. doi:10.1016/j.ygeno.2015.11.003. PMC 4727787. PMID 26554401.
Bentley D, Balasubramanian S, Swerdlow H, et al. (2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
Check Hayden, E. (2012). "Roche chases stake in medical sequencing". Nature. 484 (7393): 152. Bibcode:2012Natur.484..152C. doi:10.1038/484152a. PMID 22498604.
Balasubramanian, Shankar (2015). "Solexa Sequencing: Decoding Genomes on a Population Scale". Clinical Chemistry. 61 (1): 21–24. doi:10.1373/clinchem.2014.221747. PMID 25332311.
McKernan KJ, Peckham HE, Costa GL, et al. (2009). "Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding". Genome Res. 19 (9): 1527–1541. doi:10.1101/gr.091868.109. PMC 2752135. PMID 19546169.
Huang YF, Chen SC, Chiang YS, et al. (2012). "Palindromic sequence impedes sequencing-by-ligation mechanism". BMC Syst Biol. 6 (Suppl 2) S10. doi:10.1186/1752-0509-6-S2-S10. PMC 3521181. PMID 23281822.
Rothberg JM, Hinz H, Rearick TM, et al. (2011). "An integrated semiconductor device enabling non-optical genome sequencing". Nature. 475 (7356): 348–352. doi:10.1038/nature10242. PMID 21776081.
Loman NJ, Misra RV, Dallman TJ, et al. (2012). "Performance comparison of benchtop high-throughput sequencing platforms". Nat Biotechnol. 30 (5): 434–439. doi:10.1038/nbt.2198. PMID 22522955.
Anderson MW, Schrijver I (May 2010). "Next generation DNA sequencing and the future of genomic medicine". Genes. 1 (1): 38–69. doi:10.3390/genes1010038. PMC 3960862. PMID 24710010.
Tucker T, Marra M, Friedman JM (August 2009). "Massively parallel sequencing: the next big thing in genetic medicine". American Journal of Human Genetics. 85 (2): 142–154. doi:10.1016/j.ajhg.2009.06.022. PMC 2725244. PMID 19679224.
von Bubnoff A (March 2008). "Next-generation sequencing: the race is on". Cell. 132 (5): 721–723. doi:10.1016/j.cell.2008.02.028. PMID 18329356. S2CID 8413828.
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, et al. (November 2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
McKernan KJ, Peckham HE, Costa GL, McLaughlin SF, Fu Y, Tsung EF, et al. (September 2009). "Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding". Genome Research. 19 (9): 1527–1541. doi:10.1101/gr.091868.109. PMC 2752135. PMID 19546169.
Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, et al. (January 2010). "Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays". Science. 327 (5961): 78–81. Bibcode:2010Sci...327...78D. doi:10.1126/science.1181498. PMID 19892942. S2CID 17309571.
Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, Rosenbaum AM, et al. (September 2005). "Accurate multiplex polony sequencing of an evolved bacterial genome". Science. 309 (5741): 1728–1732. Bibcode:2005Sci...309.1728S. doi:10.1126/science.1117389. PMID 16081699. S2CID 11405973.
Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, et al. (July 2012). "Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells". Nature. 487 (7406): 190–195. Bibcode:2012Natur.487..190P. doi:10.1038/nature11236. PMC 3397394. PMID 22785314.
Voelkerding KV, Dames S, Durtschi JD (September 2010). "Next generation sequencing for clinical diagnostics-principles and application to targeted resequencing for hypertrophic cardiomyopathy: a paper from the 2009 William Beaumont Hospital Symposium on Molecular Pathology". The Journal of Molecular Diagnostics. 12 (5): 539–551. doi:10.2353/jmoldx.2010.100043. PMC 2928417. PMID 20805560.
Metzker ML (January 2010). "Sequencing technologies - the next generation". Nature Reviews. Genetics. 11 (1): 31–46. doi:10.1038/nrg2626. PMID 19997069. S2CID 205484500.
Dressman D, Yan H, Traverso G, Kinzler KW, Vogelstein B (July 2003). "Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations". Proceedings of the National Academy of Sciences of the United States of America. 100 (15): 8817–8822. Bibcode:2003PNAS..100.8817D. doi:10.1073/pnas.1133470100. PMC 166396. PMID 12857956.
Mitra RD, Church GM (December 1999). "In situ localized amplification and contact replication of many individual DNA molecules". Nucleic Acids Research. 27 (24): 34e–34. doi:10.1093/nar/27.24.e34. PMC 148757. PMID 10572186.
Ronaghi, Mostafa; Uhlén, Mathias; Nyrén, Pål (1998-07-17). "A Sequencing Method Based on Real-Time Pyrophosphate". Science. 281 (5375): 363–365. doi:10.1126/science.281.5375.363. ISSN 0036-8075. PMID 9705713. S2CID 26331871.
Chin CS, Alexander DH, Marks P, Klammer AA, Drake J, Heiner C, et al. (June 2013). "Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data". Nature Methods. 10 (6): 563–569. doi:10.1038/nmeth.2474. PMID 23644548. S2CID 205421576.

ncbi.nlm.nih.gov

Ballard D, Winkler-Galicki J, Wesoły J (July 2020). "Massive parallel sequencing in forensics: advantages, issues, technicalities, and prospects". International Journal of Legal Medicine. 134 (4): 1291–1303. doi:10.1007/s00414-020-02294-0. PMC 7295846. PMID 32451905.
Giani AM, Gallo GR, Gianfranceschi L, Formenti G (2020). "Long walk to genomics: History and current approaches to genome sequencing and assembly". Computational and Structural Biotechnology Journal. 100: 9–19. doi:10.1016/j.csbj.2019.11.002. PMC 6926122. PMID 31890139.
Margulies M, Egholm M, Altman W, et al. (2005). "Genome sequencing in microfabricated high-density picolitre reactors". Nature. 437 (7057): 376–380. Bibcode:2005Natur.437..376M. doi:10.1038/nature03959. PMC 1464427. PMID 16056220.
Heather, James M.; Chain, Benjamin (2016). "The sequence of sequencers: The history of sequencing DNA". Genomics. 107 (1): 1–8. doi:10.1016/j.ygeno.2015.11.003. PMC 4727787. PMID 26554401.
Bentley D, Balasubramanian S, Swerdlow H, et al. (2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
McKernan KJ, Peckham HE, Costa GL, et al. (2009). "Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding". Genome Res. 19 (9): 1527–1541. doi:10.1101/gr.091868.109. PMC 2752135. PMID 19546169.
Huang YF, Chen SC, Chiang YS, et al. (2012). "Palindromic sequence impedes sequencing-by-ligation mechanism". BMC Syst Biol. 6 (Suppl 2) S10. doi:10.1186/1752-0509-6-S2-S10. PMC 3521181. PMID 23281822.
Anderson MW, Schrijver I (May 2010). "Next generation DNA sequencing and the future of genomic medicine". Genes. 1 (1): 38–69. doi:10.3390/genes1010038. PMC 3960862. PMID 24710010.
Tucker T, Marra M, Friedman JM (August 2009). "Massively parallel sequencing: the next big thing in genetic medicine". American Journal of Human Genetics. 85 (2): 142–154. doi:10.1016/j.ajhg.2009.06.022. PMC 2725244. PMID 19679224.
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, et al. (November 2008). "Accurate whole human genome sequencing using reversible terminator chemistry". Nature. 456 (7218): 53–59. Bibcode:2008Natur.456...53B. doi:10.1038/nature07517. PMC 2581791. PMID 18987734.
McKernan KJ, Peckham HE, Costa GL, McLaughlin SF, Fu Y, Tsung EF, et al. (September 2009). "Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding". Genome Research. 19 (9): 1527–1541. doi:10.1101/gr.091868.109. PMC 2752135. PMID 19546169.
Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, et al. (July 2012). "Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells". Nature. 487 (7406): 190–195. Bibcode:2012Natur.487..190P. doi:10.1038/nature11236. PMC 3397394. PMID 22785314.
Voelkerding KV, Dames S, Durtschi JD (September 2010). "Next generation sequencing for clinical diagnostics-principles and application to targeted resequencing for hypertrophic cardiomyopathy: a paper from the 2009 William Beaumont Hospital Symposium on Molecular Pathology". The Journal of Molecular Diagnostics. 12 (5): 539–551. doi:10.2353/jmoldx.2010.100043. PMC 2928417. PMID 20805560.
Dressman D, Yan H, Traverso G, Kinzler KW, Vogelstein B (July 2003). "Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations". Proceedings of the National Academy of Sciences of the United States of America. 100 (15): 8817–8822. Bibcode:2003PNAS..100.8817D. doi:10.1073/pnas.1133470100. PMC 166396. PMID 12857956.
Mitra RD, Church GM (December 1999). "In situ localized amplification and contact replication of many individual DNA molecules". Nucleic Acids Research. 27 (24): 34e–34. doi:10.1093/nar/27.24.e34. PMC 148757. PMID 10572186.

science.org (Global: 1,160^th place; English: 737^th place)

Ronaghi, Mostafa; Uhlén, Mathias; Nyrén, Pål (1998-07-17). "A Sequencing Method Based on Real-Time Pyrophosphate". Science. 281 (5375): 363–365. doi:10.1126/science.281.5375.363. ISSN 0036-8075. PMID 9705713. S2CID 26331871.

semanticscholar.org (Global: 11^th place; English: 8^th place)

api.semanticscholar.org

von Bubnoff A (March 2008). "Next-generation sequencing: the race is on". Cell. 132 (5): 721–723. doi:10.1016/j.cell.2008.02.028. PMID 18329356. S2CID 8413828.
Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, et al. (January 2010). "Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays". Science. 327 (5961): 78–81. Bibcode:2010Sci...327...78D. doi:10.1126/science.1181498. PMID 19892942. S2CID 17309571.
Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, Rosenbaum AM, et al. (September 2005). "Accurate multiplex polony sequencing of an evolved bacterial genome". Science. 309 (5741): 1728–1732. Bibcode:2005Sci...309.1728S. doi:10.1126/science.1117389. PMID 16081699. S2CID 11405973.
Metzker ML (January 2010). "Sequencing technologies - the next generation". Nature Reviews. Genetics. 11 (1): 31–46. doi:10.1038/nrg2626. PMID 19997069. S2CID 205484500.
Ronaghi, Mostafa; Uhlén, Mathias; Nyrén, Pål (1998-07-17). "A Sequencing Method Based on Real-Time Pyrophosphate". Science. 281 (5375): 363–365. doi:10.1126/science.281.5375.363. ISSN 0036-8075. PMID 9705713. S2CID 26331871.
Chin CS, Alexander DH, Marks P, Klammer AA, Drake J, Heiner C, et al. (June 2013). "Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data". Nature Methods. 10 (6): 563–569. doi:10.1038/nmeth.2474. PMID 23644548. S2CID 205421576.

slideshare.net (Global: 2,161^st place; English: 2,535^th place)

Mayer P, Matton G, Adessi C, Turcatti G, Mermod JJ, Kawashima E (October 7–10, 1998). A very large scale, high throughput and low cost DNA sequencing method based on a new 2-dimensional DNA auto-patterning process. Fifth International Automation in Mapping and DNA Sequencing Conference. St. Louis, MO, USA. DNA colony massively parallel sequencing ams98 presentation

technologyreview.com (Global: 1,943^rd place; English: 1,253^rd place)

Zimmerman, Eilene (18 February 2014). "50 Smartest Companies: Illumina". MIT Technology Review. Massachusetts Institute of Technology. Archived from the original on 11 December 2015. Retrieved 25 August 2014.
Regalado, Antonio. "EmTech: Illumina Says 228,000 Human Genomes Will Be Sequenced This Year". MIT Technology Review. Massachusetts Institute of Technology. Archived from the original on 26 December 2015. Retrieved 26 September 2014.

web.archive.org (Global: 1^st place; English: 1^st place)

"Program Announcement Concept: Technology Development for the $1000 Genome". Archived from the original on March 1, 2025. Retrieved April 6, 2026. {{cite web}}: Check date values in: |access-date= (help)
Zimmerman, Eilene (18 February 2014). "50 Smartest Companies: Illumina". MIT Technology Review. Massachusetts Institute of Technology. Archived from the original on 11 December 2015. Retrieved 25 August 2014.
Regalado, Antonio. "EmTech: Illumina Says 228,000 Human Genomes Will Be Sequenced This Year". MIT Technology Review. Massachusetts Institute of Technology. Archived from the original on 26 December 2015. Retrieved 26 September 2014.
Clark, Liat (15 Jan 2014). "Illumina announces landmark $1,000 human genome sequencing". Wired. Archived from the original on 4 November 2019. Retrieved 4 Nov 2019.
"Specifications for HiSeq 2500". Archived from the original on 2014-12-06. Retrieved 2014-11-06.
"HiSeq v4 is here… and it delivers | Edinburgh Genomics". Archived from the original on 2014-11-06. Retrieved 2014-11-06.
"Ion Torrent". Archived from the original on 30 December 2013. Retrieved 1 Jan 2014.
"Assay Technology". Illumina. Archived from the original on 2012-08-26. Retrieved 2012-08-05.
"True Single Molecule Sequencing (tSMS™): Helicos BioSciences". Helicosbio.com. Archived from the original on 2012-03-11. Retrieved 2012-08-05.
"PacBio Announces Sequel Sequencing System - Bio-IT World". www.bio-itworld.com. Archived from the original on 2015-10-02.

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EP 0972081, Farinelli L, Kawashima E, Mayer P ), "Method of nucleic acid amplification", published 2007-06-13, assigned to Solexa Ltd.
EP 0975802, Kawashima E, Farinellit L, Mayer P, "Method of nucleic acid sequencing", published 2004-06-23

wired.co.uk (Global: 2,053^rd place; English: 1,340^th place)

Clark, Liat (15 Jan 2014). "Illumina announces landmark $1,000 human genome sequencing". Wired. Archived from the original on 4 November 2019. Retrieved 4 Nov 2019.

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Ronaghi, Mostafa; Uhlén, Mathias; Nyrén, Pål (1998-07-17). "A Sequencing Method Based on Real-Time Pyrophosphate". Science. 281 (5375): 363–365. doi:10.1126/science.281.5375.363. ISSN 0036-8075. PMID 9705713. S2CID 26331871.

Massive parallel sequencing (English Wikipedia)

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