Mefloquine (English Wikipedia)

"www.cdc.gov" (PDF). Archived (PDF) from the original on 2015-02-09.
"Mefloquine" (PDF). Medicines for the Prevention of Malaria While Traveling. Atlanta, Georgia: Centers for Disease Control and Prevention. 2019. Retrieved 2019-03-30.

wwwnc.cdc.gov

"Malaria - Chapter 3 - 2014 Yellow Book | Travelers' Health | CDC". Archived from the original on 2014-12-26.

ctvnews.ca

Haines A (18 October 2019). "Canadian soldiers allege anti-malaria medication left them with intense rage, suicidal ideations". W5. Retrieved 16 April 2020.

doi.org

Croft AM (April 2007). "A lesson learnt: the rise and fall of Lariam and Halfan". Journal of the Royal Society of Medicine. 100 (4): 170–174. doi:10.1177/014107680710011411. PMC 1847738. PMID 17404338.
Schlagenhauf P, Adamcova M, Regep L, Schaerer MT, Rhein HG (December 2010). "The position of mefloquine as a 21st century malaria chemoprophylaxis". Malaria Journal. 9: 357. doi:10.1186/1475-2875-9-357. PMC 3224336. PMID 21143906.
Schlagenhauf P (June 1999). "Mefloquine for malaria chemoprophylaxis 1992-1998: a review". Journal of Travel Medicine. 6 (2): 122–133. doi:10.1111/j.1708-8305.1999.tb00843.x. PMID 10381965.
Tickell-Painter M, Maayan N, Saunders R, Pace C, Sinclair D (October 2017). "Mefloquine for preventing malaria during travel to endemic areas". The Cochrane Database of Systematic Reviews. 2017 (10): CD006491. doi:10.1002/14651858.CD006491.pub4. PMC 5686653. PMID 29083100.
Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, et al. (2004). "Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number". Lancet. 364 (9432): 438–447. doi:10.1016/S0140-6736(04)16767-6. PMC 4337987. PMID 15288742.
AlKadi HO (2007). "Antimalarial drug toxicity: a review". Chemotherapy. 53 (6): 385–391. doi:10.1159/000109767. PMID 17934257. S2CID 7888082.
González R, Hellgren U, Greenwood B, Menéndez C (February 2014). "Mefloquine safety and tolerability in pregnancy: a systematic literature review". Malaria Journal. 13: 75. doi:10.1186/1475-2875-13-75. PMC 3942617. PMID 24581338.
Schlagenhauf P, Blumentals WA, Suter P, Regep L, Vital-Durand G, Schaerer MT, et al. (June 2012). "Pregnancy and fetal outcomes after exposure to mefloquine in the pre- and periconception period and during pregnancy". Clinical Infectious Diseases. 54 (11): e124–e131. doi:10.1093/cid/cis215. PMC 3348951. PMID 22495078.
Hennequin C, Bourée P, Bazin N, Bisaro F, Feline A (October 1994). "Severe psychiatric side effects observed during prophylaxis and treatment with mefloquine". Archives of Internal Medicine. 154 (20): 2360–2362. doi:10.1001/archinte.1994.00420200116012. PMID 7944858.
Speich R, Haller A (July 1994). "Central anticholinergic syndrome with the antimalarial drug mefloquine". The New England Journal of Medicine. 331 (1): 57–58. doi:10.1056/NEJM199407073310120. PMID 8202114.
Overbosch D, Schilthuis H, Bienzle U, Behrens RH, Kain KC, Clarke PD, et al. (October 2001). "Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study". Clinical Infectious Diseases. 33 (7): 1015–1021. doi:10.1086/322694. PMID 11528574.
Gofton TE, Al-Khotani A, O'Farrell B, Ang LC, McLachlan RS (April 2011). "Mefloquine in the treatment of progressive multifocal leukoencephalopathy". Journal of Neurology, Neurosurgery, and Psychiatry. 82 (4): 452–455. doi:10.1136/jnnp.2009.190652. PMID 20562463. S2CID 19877728. Archived from the original on 2012-03-21. Retrieved 2011-10-16.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Quinones-Lopez MC, Rosenfeld CA, et al. (December 2005). "Mefloquine inhibits cholinesterases at the mouse neuromuscular junction". Neuropharmacology. 49 (8): 1132–1139. doi:10.1016/j.neuropharm.2005.06.011. PMID 16081111. S2CID 28938736.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Hognason K (March 2006). "Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals". Neuropharmacology. 50 (3): 345–353. doi:10.1016/j.neuropharm.2005.09.011. PMID 16288931. S2CID 13245990.
Zhou C, Xiao C, McArdle JJ, Ye JH (June 2006). "Mefloquine enhances nigral gamma-aminobutyric acid release via inhibition of cholinesterase". The Journal of Pharmacology and Experimental Therapeutics. 317 (3): 1155–1160. doi:10.1124/JPET.106.101923. PMID 16501066. S2CID 22205111.

drugs.com

"Mefloquine (Lariam) Use During Pregnancy". Drugs.com. Retrieved 31 March 2019.
"Mefloquine Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 2015-12-08. Retrieved 27 Nov 2015.
"Lariam". The American Society of Health-System Pharmacists. Archived from the original on 7 January 2012. Retrieved 3 April 2011.

fda.gov

"www.fda.gov" (PDF). Food and Drug Administration. Archived (PDF) from the original on 2014-06-30.
"FDA Drug Safety Communication: FDA approves label changes for antimalarial drug mefloquine hydrochloride due to risk of serious psychiatric and nerve side effects". Food and Drug Administration.

accessdata.fda.gov

"Lariam medication guide" (PDF). Hoffman La Roche. Archived (PDF) from the original on 2 October 2013. Retrieved 27 September 2013.

handle.net

hdl.handle.net

World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.

idsociety.org

"www.idsociety.org" (PDF). Archived (PDF) from the original on 2015-03-19.

ipolitics.ca

"Germany bans drug linked to brain damage, ramps up pressure on Canada". iPolitics. 9 December 2016.

legionmagazine.com

Adams S (6 September 2017). "Cure or curse?". Canvet Publications Ltd. Legion Magazine.

medicines.org.uk

"Lariam 250 mg tablets - Summary of Product Characteristics (SmPC)". (emc). 3 April 2019. Retrieved 8 September 2020.

nih.gov

pubmed.ncbi.nlm.nih.gov

Croft AM (April 2007). "A lesson learnt: the rise and fall of Lariam and Halfan". Journal of the Royal Society of Medicine. 100 (4): 170–174. doi:10.1177/014107680710011411. PMC 1847738. PMID 17404338.
Schlagenhauf P, Adamcova M, Regep L, Schaerer MT, Rhein HG (December 2010). "The position of mefloquine as a 21st century malaria chemoprophylaxis". Malaria Journal. 9: 357. doi:10.1186/1475-2875-9-357. PMC 3224336. PMID 21143906.
Schlagenhauf P (June 1999). "Mefloquine for malaria chemoprophylaxis 1992-1998: a review". Journal of Travel Medicine. 6 (2): 122–133. doi:10.1111/j.1708-8305.1999.tb00843.x. PMID 10381965.
Tickell-Painter M, Maayan N, Saunders R, Pace C, Sinclair D (October 2017). "Mefloquine for preventing malaria during travel to endemic areas". The Cochrane Database of Systematic Reviews. 2017 (10): CD006491. doi:10.1002/14651858.CD006491.pub4. PMC 5686653. PMID 29083100.
Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, et al. (2004). "Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number". Lancet. 364 (9432): 438–447. doi:10.1016/S0140-6736(04)16767-6. PMC 4337987. PMID 15288742.
AlKadi HO (2007). "Antimalarial drug toxicity: a review". Chemotherapy. 53 (6): 385–391. doi:10.1159/000109767. PMID 17934257. S2CID 7888082.
González R, Hellgren U, Greenwood B, Menéndez C (February 2014). "Mefloquine safety and tolerability in pregnancy: a systematic literature review". Malaria Journal. 13: 75. doi:10.1186/1475-2875-13-75. PMC 3942617. PMID 24581338.
Croft AM (July 2010). "Malaria: prevention in travellers". BMJ Clinical Evidence. 2010. PMC 3217660. PMID 21418669.
Schlagenhauf P, Blumentals WA, Suter P, Regep L, Vital-Durand G, Schaerer MT, et al. (June 2012). "Pregnancy and fetal outcomes after exposure to mefloquine in the pre- and periconception period and during pregnancy". Clinical Infectious Diseases. 54 (11): e124–e131. doi:10.1093/cid/cis215. PMC 3348951. PMID 22495078.
Hennequin C, Bourée P, Bazin N, Bisaro F, Feline A (October 1994). "Severe psychiatric side effects observed during prophylaxis and treatment with mefloquine". Archives of Internal Medicine. 154 (20): 2360–2362. doi:10.1001/archinte.1994.00420200116012. PMID 7944858.
Speich R, Haller A (July 1994). "Central anticholinergic syndrome with the antimalarial drug mefloquine". The New England Journal of Medicine. 331 (1): 57–58. doi:10.1056/NEJM199407073310120. PMID 8202114.
Overbosch D, Schilthuis H, Bienzle U, Behrens RH, Kain KC, Clarke PD, et al. (October 2001). "Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study". Clinical Infectious Diseases. 33 (7): 1015–1021. doi:10.1086/322694. PMID 11528574.
Gofton TE, Al-Khotani A, O'Farrell B, Ang LC, McLachlan RS (April 2011). "Mefloquine in the treatment of progressive multifocal leukoencephalopathy". Journal of Neurology, Neurosurgery, and Psychiatry. 82 (4): 452–455. doi:10.1136/jnnp.2009.190652. PMID 20562463. S2CID 19877728. Archived from the original on 2012-03-21. Retrieved 2011-10-16.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Quinones-Lopez MC, Rosenfeld CA, et al. (December 2005). "Mefloquine inhibits cholinesterases at the mouse neuromuscular junction". Neuropharmacology. 49 (8): 1132–1139. doi:10.1016/j.neuropharm.2005.06.011. PMID 16081111. S2CID 28938736.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Hognason K (March 2006). "Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals". Neuropharmacology. 50 (3): 345–353. doi:10.1016/j.neuropharm.2005.09.011. PMID 16288931. S2CID 13245990.
Zhou C, Xiao C, McArdle JJ, Ye JH (June 2006). "Mefloquine enhances nigral gamma-aminobutyric acid release via inhibition of cholinesterase". The Journal of Pharmacology and Experimental Therapeutics. 317 (3): 1155–1160. doi:10.1124/JPET.106.101923. PMID 16501066. S2CID 22205111.

ncbi.nlm.nih.gov

Croft AM (April 2007). "A lesson learnt: the rise and fall of Lariam and Halfan". Journal of the Royal Society of Medicine. 100 (4): 170–174. doi:10.1177/014107680710011411. PMC 1847738. PMID 17404338.
Schlagenhauf P, Adamcova M, Regep L, Schaerer MT, Rhein HG (December 2010). "The position of mefloquine as a 21st century malaria chemoprophylaxis". Malaria Journal. 9: 357. doi:10.1186/1475-2875-9-357. PMC 3224336. PMID 21143906.
Tickell-Painter M, Maayan N, Saunders R, Pace C, Sinclair D (October 2017). "Mefloquine for preventing malaria during travel to endemic areas". The Cochrane Database of Systematic Reviews. 2017 (10): CD006491. doi:10.1002/14651858.CD006491.pub4. PMC 5686653. PMID 29083100.
Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, et al. (2004). "Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number". Lancet. 364 (9432): 438–447. doi:10.1016/S0140-6736(04)16767-6. PMC 4337987. PMID 15288742.
González R, Hellgren U, Greenwood B, Menéndez C (February 2014). "Mefloquine safety and tolerability in pregnancy: a systematic literature review". Malaria Journal. 13: 75. doi:10.1186/1475-2875-13-75. PMC 3942617. PMID 24581338.
Croft AM (July 2010). "Malaria: prevention in travellers". BMJ Clinical Evidence. 2010. PMC 3217660. PMID 21418669.
Schlagenhauf P, Blumentals WA, Suter P, Regep L, Vital-Durand G, Schaerer MT, et al. (June 2012). "Pregnancy and fetal outcomes after exposure to mefloquine in the pre- and periconception period and during pregnancy". Clinical Infectious Diseases. 54 (11): e124–e131. doi:10.1093/cid/cis215. PMC 3348951. PMID 22495078.

dailymed.nlm.nih.gov

"Lariam brand of mefloquine hydrochloride tablets". DailyMed. Retrieved 9 October 2022.
"Mefloquine hydrochloride tablet". DailyMed. 31 May 2016. Retrieved 8 September 2020.

rochecanada.com

"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 3. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 4. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 6. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 18. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.

semanticscholar.org

api.semanticscholar.org

AlKadi HO (2007). "Antimalarial drug toxicity: a review". Chemotherapy. 53 (6): 385–391. doi:10.1159/000109767. PMID 17934257. S2CID 7888082.
Gofton TE, Al-Khotani A, O'Farrell B, Ang LC, McLachlan RS (April 2011). "Mefloquine in the treatment of progressive multifocal leukoencephalopathy". Journal of Neurology, Neurosurgery, and Psychiatry. 82 (4): 452–455. doi:10.1136/jnnp.2009.190652. PMID 20562463. S2CID 19877728. Archived from the original on 2012-03-21. Retrieved 2011-10-16.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Quinones-Lopez MC, Rosenfeld CA, et al. (December 2005). "Mefloquine inhibits cholinesterases at the mouse neuromuscular junction". Neuropharmacology. 49 (8): 1132–1139. doi:10.1016/j.neuropharm.2005.06.011. PMID 16081111. S2CID 28938736.
McArdle JJ, Sellin LC, Coakley KM, Potian JG, Hognason K (March 2006). "Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals". Neuropharmacology. 50 (3): 345–353. doi:10.1016/j.neuropharm.2005.09.011. PMID 16288931. S2CID 13245990.
Zhou C, Xiao C, McArdle JJ, Ye JH (June 2006). "Mefloquine enhances nigral gamma-aminobutyric acid release via inhibition of cholinesterase". The Journal of Pharmacology and Experimental Therapeutics. 317 (3): 1155–1160. doi:10.1124/JPET.106.101923. PMID 16501066. S2CID 22205111.

telegraph.co.uk

"Did Lariam send Cambridge student Alana Cutland to her death… and what anti-malarials should children take on their gap year?". Telegraph Media Group Limited. 3 August 2019.

theguardian.com

"'It's not a benign drug - it has ruined my life'". Guardian News & Media Limited. 24 October 2002.

traveldoctor.co.uk

"Malaria Information". Traveldoctor. Archived from the original on 28 June 2016. Retrieved 9 July 2016.

web.archive.org

"Mefloquine Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 2015-12-08. Retrieved 27 Nov 2015.
"Lariam". The American Society of Health-System Pharmacists. Archived from the original on 7 January 2012. Retrieved 3 April 2011.
"www.idsociety.org" (PDF). Archived (PDF) from the original on 2015-03-19.
"Malaria - Chapter 3 - 2014 Yellow Book | Travelers' Health | CDC". Archived from the original on 2014-12-26.
"Lariam medication guide" (PDF). Hoffman La Roche. Archived (PDF) from the original on 2 October 2013. Retrieved 27 September 2013.
"www.cdc.gov" (PDF). Archived (PDF) from the original on 2015-02-09.
"Malaria Information". Traveldoctor. Archived from the original on 28 June 2016. Retrieved 9 July 2016.
"www.fda.gov" (PDF). Food and Drug Administration. Archived (PDF) from the original on 2014-06-30.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 3. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 4. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 6. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
"Lariam product monogram" (PDF). Hoffman La Roche Limited. p. 18. Archived from the original (PDF) on 17 December 2011. Retrieved 24 April 2011.
Gofton TE, Al-Khotani A, O'Farrell B, Ang LC, McLachlan RS (April 2011). "Mefloquine in the treatment of progressive multifocal leukoencephalopathy". Journal of Neurology, Neurosurgery, and Psychiatry. 82 (4): 452–455. doi:10.1136/jnnp.2009.190652. PMID 20562463. S2CID 19877728. Archived from the original on 2012-03-21. Retrieved 2011-10-16.