Metamizole (English Wikipedia)

"Metamizole". European pharmacopoeia (English 8.1 ed.). Council Of Europe: European Directorate for the Quality of Medicines and Healthcare. 2013. p. 3791. ISBN 978-92-871-7527-4.

bbc.com

Biernath A (2023-08-17). "Dipirona: por que é vendida no Brasil, mas proibida nos EUA e em parte da Europa?". BBC News Brasil (in Brazilian Portuguese). Archived from the original on 2023-10-14. Retrieved 2023-09-21.

bfarm.de

"Risikoinformationen - Metamizol (Novalgin, Berlosin, Novaminsulfon, etc.): BfArM weist auf richtige Indikationsstellung und Beachtung von Vorsichtsmaßnahmen und Warnhinweisen hin" [Risk information - Metamizol (Novalgin, Berlosin, Novaminsulfon, etc.): BfArM points out the correct indication and compliance with precautionary measures and warnings]. Bundesinstitut für Arzneimittel und Medizinprodukte (Federal Institute for Pharmaceuticals and Medical Products). 2009-05-28. Archived from the original on 2023-05-18. Retrieved 2023-08-04.

books.google.com

Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 530. ISBN 978-3-527-60749-5.
"New and Nonofficial Remedies: Melubrine". JAMA. 61 (11): 869. 1913.

business-standard.com

"Govt lifts ban on painkiller Analgin". Business Standard India. 19 March 2014. Archived from the original on 7 January 2018. Retrieved 7 January 2018.

canada.ca

"Notice of Amendment: Addition of Metamizole (Dipyrone) to the Prescription Drug List (PDL)". Government of Canada. 2022-07-18. Archived from the original on 2022-08-30. Retrieved 2023-08-04.

cdsco.gov.in

Panda AK (2014-02-13). Drugs Rules - G.S.R. 86(E) 13.02.2014 Revoke GSR378(E) Reg. Suspension of Analgin (PDF) (Report). New Delhi: The Gazette of India. Archived (PDF) from the original on 2023-08-11. Retrieved 2023-08-11.

creativecommons.org

Schmelzer KP, Liebetrau D, Kämmerer W, Meisinger C, Hyhlik-Dürr A (April 2023). "Strategies for Avoiding Typical Drug-Drug Interactions and Drug-Related Problems in Patients with Vascular Diseases". Medicina (Kaunas). 59 (4): 780. doi:10.3390/medicina59040780. PMC 10142821. PMID 37109738. This article incorporates text from this source, which is available under the CC BY 4.0 license.

doi.org

Brune K (December 1997). "The early history of non-opioid analgesics". Acute Pain. 1: 33–40. doi:10.1016/S1366-0071(97)80033-2.
Jage J, Laufenberg-Feldmann R, Heid F (April 2008). "[Medikamente zur postoperativen Schmerztherapie: Bewährtes und Neues. Teil 1: Nichtopioide]" [Drugs for postoperative analgesia: routine and new aspects. Part 1: non-opioids]. Der Anaesthesist (in German). 57 (4): 382–390. doi:10.1007/s00101-008-1326-x. PMID 18351305. S2CID 32814418.
Stromer W, Palladini M (2022). "Metamizole: A comprehensive approach to its benefit-risk profile". Evidence for Self-Medication. 2. doi:10.52778/efsm.22.0153.
Brack A, Rittner HL, Schäfer M (March 2004). "Nichtopioidanalgetika zur perioperativen Schmerztherapie" [Non-opioid analgesics for perioperative pain therapy. Risks and rational basis for use]. Der Anaesthesist (in German). 53 (3): 263–280. doi:10.1007/s00101-003-0641-5. PMID 15021958. S2CID 8829564.
Petkova V, Valchanova V, Ibrahim A, Nikolova I, Benbasat N, Dimitrov M (March 2014). "Marketing approaches for OTC analgesics in Bulgaria". Biotechnology, Biotechnological Equipment. 28 (2): 360–365. doi:10.1080/13102818.2014.911477. PMC 4433822. PMID 26019521.
Lutz M (November 2019). "Metamizole (Dipyrone) and the Liver: A Review of the Literature". Journal of Clinical Pharmacology. 59 (11): 1433–1442. doi:10.1002/jcph.1512. PMID 31433499. S2CID 201118022.
Nikolova I, Tencheva J, Voinikov J, Petkova V, Benbasat N, Danchev N (2014). "Metamizole: A Review Profile of a Well-Known "Forgotten" Drug. Part I: Pharmaceutical and Nonclinical Profile". Biotechnology & Biotechnological Equipment. 26 (6): 3329–3337. doi:10.5504/BBEQ.2012.0089. ISSN 1310-2818. S2CID 56205439.
Sznejder H, Amand C, Stewart A, Salazar R, Scala WA (2022). "Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients". Einstein. 20. Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein: eAO6353. doi:10.31744/einstein_journal/2022ao6353. PMC 9060643. PMID 35584441.
Lampl C, Likar R (December 2014). "[Metamizole (dipyrone): mode of action, drug-drug interactions, and risk of agranulocytosis]". Schmerz (in German). 28 (6): 584–90. doi:10.1007/s00482-014-1490-7. PMID 25199942.
Collares EF, Troncon LE (January 2019). "Effects of dipyrone on the digestive tract". Braz J Med Biol Res. 52 (2): e8103. doi:10.1590/1414-431X20188103. PMC 6328969. PMID 30652827.
Jasiecka A, Maślanka T, Jaroszewski JJ (2014). "Pharmacological characteristics of metamizole". Polish Journal of Veterinary Sciences. 17 (1): 207–214. doi:10.2478/pjvs-2014-0030. PMID 24724493.
Pogatzki-Zahn E, Chandrasena C, Schug SA (October 2014). "Nonopioid analgesics for postoperative pain management". Current Opinion in Anesthesiology. 27 (5): 513–519. doi:10.1097/ACO.0000000000000113. PMID 25102238. S2CID 31337982.
Reis SL, Batista AP, Assumpção J, Ramos ER, Colacite J, Souza LF (2022-10-09). "A bibliographic analysis on the use of Dipyrone and Agranulocytosis". Research, Society and Development. 11 (13): e369111335570. doi:10.33448/rsd-v11i13.35570. S2CID 252870061. Archived from the original on 2023-07-19. Retrieved 2023-07-19.
García-Martín E, Esguevillas G, Blanca-López N, García-Menaya J, Blanca M, Amo G, et al. (September 2015). "Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis". Pharmacogenetics and Genomics. 25 (9): 462–464. doi:10.1097/FPC.0000000000000157. PMID 26111152.
Mérida Rodrigo L, Faus Felipe V, Poveda Gómez F, García Alegría J (April 2009). "Agranulocitosis por metamizol: un potencial problema en la población británica" [Agranulocytosis from metamizole: a potential problem for the British population]. Revista Clínica Española (in Spanish). 209 (4): 176–179. doi:10.1016/s0014-2565(09)71310-4. PMID 19457324.
Kötter T, da Costa BR, Fässler M, Blozik E, Linde K, Jüni P, et al. (13 April 2015). "Metamizole-associated adverse events: a systematic review and meta-analysis". PLOS ONE. 10 (4). Public Library of Science (PLoS): e0122918. Bibcode:2015PLoSO..1022918K. doi:10.1371/journal.pone.0122918. PMC 4405027. PMID 25875821.
Andrade S, Bartels DB, Lange R, Sandford L, Gurwitz J (October 2016). "Safety of metamizole: a systematic review of the literature". Journal of Clinical Pharmacy and Therapeutics. 41 (5): 459–477. doi:10.1111/jcpt.12422. PMID 27422768. S2CID 24538147.
Lutz M (November 2019). "Metamizole (Dipyrone) and the Liver: A Review of the Literature". J Clin Pharmacol. 59 (11): 1433–1442. doi:10.1002/jcph.1512. PMID 31433499.
Schmelzer KP, Liebetrau D, Kämmerer W, Meisinger C, Hyhlik-Dürr A (April 2023). "Strategies for Avoiding Typical Drug-Drug Interactions and Drug-Related Problems in Patients with Vascular Diseases". Medicina (Kaunas). 59 (4): 780. doi:10.3390/medicina59040780. PMC 10142821. PMID 37109738. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Monteiro B, Steagall PV (November 2019). "Antiinflammatory Drugs". The Veterinary Clinics of North America. Small Animal Practice. 49 (6): 993–1011. doi:10.1016/j.cvsm.2019.07.009. PMID 31519356. Metamizole (dipyrone) is considered an atypical NSAID with weak antiinflammatory properties, but potent analgesic effects that are thought to be related mainly via central inhibition of COX-3 enzyme
Bachmann F, Duthaler U, Rudin D, Krähenbühl S, Haschke M (July 2018). "N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole". European Journal of Pharmaceutical Sciences. 120: 172–180. doi:10.1016/j.ejps.2018.05.003. PMID 29746911.
Lupu G, Bel L, Andrei S (November 2022). "Pain Management and Analgesics Used in Small Mammals during Post-Operative Period with an Emphasis on Metamizole (Dipyrone) as an Alternative Medication". Molecules. 27 (21): 7434. doi:10.3390/molecules27217434. PMC 9657641. PMID 36364259.
Crunfli F, Vilela FC, Giusti-Paiva A (March 2015). "Cannabinoid CB1 receptors mediate the effects of dipyrone". Clinical and Experimental Pharmacology & Physiology. 42 (3): 246–255. doi:10.1111/1440-1681.12347. PMID 25430877. S2CID 13598808.
Gonçalves Dos Santos G, Vieira WF, Vendramini PH, Bassani da Silva B, Fernandes Magalhães S, Tambeli CH, et al. (May 2020). "Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB₂ and kappa-opioid receptors activation". European Journal of Pharmacology. 874: 173005. doi:10.1016/j.ejphar.2020.173005. PMID 32057719. S2CID 211112059.
Malvar D, Aguiar FA, Vaz A, Assis DC, de Melo MC, Jabor VA, et al. (August 2014). "Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever". British Journal of Pharmacology. 171 (15): 3666–3679. doi:10.1111/bph.12717. PMC 4128064. PMID 24712707.
Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, et al. (January 2012). "Novel bioactive metabolites of dipyrone (metamizol)". Bioorganic & Medicinal Chemistry. 20 (1): 101–107. doi:10.1016/j.bmc.2011.11.028. PMC 3248997. PMID 22172309.
Bhaumik S (July 2013). "India's health ministry bans pioglitazone, metamizole, and flupentixol-melitracen". BMJ. 347: f4366. doi:10.1136/bmj.f4366. PMID 23833116. S2CID 45107003.
Bonkowsky JL, Frazer JK, Buchi KF, Byington CL (June 2002). "Metamizole use by Latino immigrants: a common and potentially harmful home remedy". Pediatrics. 109 (6): e98. doi:10.1542/peds.109.6.e98. PMID 12042592. Archived from the original on 2024-03-15. Retrieved 2024-03-15.
Garcia S, Canoniero M, Lopes G, Soriano AO (September 2006). "Metamizole use among Hispanics in Miami: report of a survey conducted in a primary care setting". Southern Medical Journal. 99 (9): 924–926. doi:10.1097/01.smj.0000233020.68212.8f. PMID 17004525. S2CID 41638378.
Taylor L, Abarca S, Henry B, Friedman L (September 2001). "Use of Neo-melubrina, a banned antipyretic drug, in San Diego, California: a survey of patients and providers". The Western Journal of Medicine. 175 (3): 159–163. doi:10.1136/ewjm.175.3.159. PMC 1071527. PMID 11527837.
Preissner S, Siramshetty VB, Dunkel M, Steinborn P, Luft FC, Preissner R (2019). "Pain-Prescription Differences - An Analysis of 500,000 Discharge Summaries". Current Drug Research Reviews. 11 (1): 58–66. doi:10.2174/1874473711666180911091846. PMID 30207223. S2CID 52192130.
Dinavitser N (January 2020). "Dipyrone – a Good Medication with a Bad Reputation". Journal of Medical Toxicology. 16 (1). Rambam Health Care Campus, Haifa, Israel: American College of Medical Toxicology: 75–86. doi:10.1007/s13181-019-00743-w. PMC 6942089. PMID 31721040. ACMT/IST 2019 American-Israeli Medical Toxicology Conference
Aragão RB, Semensatto D, Calixto LA, Labuto G (2020). "Pharmaceutical market, environmental public policies and water quality: the case of the São Paulo Metropolitan Region, Brazil". Cadernos de Saúde Pública. 36 (11): e00192319. doi:10.1590/0102-311x00192319. ISSN 1678-4464. PMID 33237204. S2CID 227168554.

epam.ru

"Pavel Sadovsky comments on trademarks registering for RIA Novosti - Insights". EPAM Law. 2012-02-22. Archived from the original on 2021-02-25. Retrieved 2023-08-14.

europa.eu

ema.europa.eu

"Metamizole Annex I - List of nationally authorised medicinal products" (PDF). European Medicines Agency. 2018-06-01. Archived (PDF) from the original on 2022-02-05. Retrieved 2023-08-14.
European Medicines Agency (2018-09-17). "Metamizole containing medicinal products - EMA recommends aligning doses of metamizole medicines and their use during pregnancy and breastfeeding". European Medicines Agency. Archived from the original on 2023-02-01. Retrieved 2023-08-04.
- CHMP (2018-12-13). "Metamizole - Assessment report" (PDF). European Medicines Agency (published 2019-03-28). Archived (PDF) from the original on 2022-02-05. Retrieved 2023-08-03.
- Assessment report: metamizole-containing medicinal products (PDF) (Report). European Medicines Agency, Committee for Medicinal Products for Human Use (CHMP). 13 December 2018. EMA/143912/2019. Archived (PDF) from the original on 5 February 2022. Retrieved 4 August 2023.

fda.gov

FDA's Center for Veterinary Medicine (November 26, 2019). "Zimeta (dipyrone injection) - Veterinarians". FDA. Archived from the original on 2022-01-17. Retrieved 2023-08-04.

ffbh.bg

"Sopharma wins TM battle over analgesic drug Analgin". FFBH. 2004-08-05. Archived from the original on 2023-08-14. Retrieved 2023-08-14.

govinfo.gov

Gardner S (1977-06-07). Drug products containing dipyrone - Withdrawal of Approval of New Drug Applications (Report). Vol. 42. Federal Register (published 1977-06-17). pp. 30893–4. ISSN 0097-6326. Archived from the original on 2020-09-29. Retrieved 2023-08-04. This notice withdraws approval of the new drug applications (NDA's) for drug products containing dipyrone. The drug products have been used to reduce fever, but they are not shown to be safe for use. On the basis of new evidence, not contained in the applications or not available until after the applications were approved, evaluated together with the evidence available when the applications were approved, the Commissioner of Food and Drugs finds that such drugs have not been shown to be safe for use upon the basis of which the applications were approved. (...) approval of the NDA's providing for the drug products named above, and all amendments and supplements applying thereto, is withdrawn effective June 27,1977. Shipment in interstate commerce of the above-listed products or of any identical, related, or similar product, not the subject of an approved NDA, will then be unlawful.

harvard.edu

ui.adsabs.harvard.edu

Kötter T, da Costa BR, Fässler M, Blozik E, Linde K, Jüni P, et al. (13 April 2015). "Metamizole-associated adverse events: a systematic review and meta-analysis". PLOS ONE. 10 (4). Public Library of Science (PLoS): e0122918. Bibcode:2015PLoSO..1022918K. doi:10.1371/journal.pone.0122918. PMC 4405027. PMID 25875821.

iz.ru

Ovchinnikov R (2011-12-22). "Анальгин хотят отпустить в одни руки" [Analgin want to let go in one hand]. Известия (in Russian). Archived from the original on 2023-08-12.

kgnews.co.kr

Kim CH (2004-08-26). "해열진통제 '설피린' 국내사용 논란" [Controversy over domestic use of antipyretic analgesic Sulpyrin]. 경기신문 [kgnews] (in Korean). Archived from the original on 2023-08-14. Retrieved 2023-08-14.

medsafe.govt.nz

"Recent NZ Gazette Notices Relating to Classification". medsafe.govt.nz. 2020-03-06. Archived from the original on 2023-04-29. Retrieved 2023-08-04.
"Minutes of the 63rd meeting of the Medicines Classification Committee - 10 Oct 2019". medsafe.govt.nz. 2019-12-04. Archived from the original on 2023-06-10. Retrieved 2023-08-04.

nih.gov

pubmed.ncbi.nlm.nih.gov

Jage J, Laufenberg-Feldmann R, Heid F (April 2008). "[Medikamente zur postoperativen Schmerztherapie: Bewährtes und Neues. Teil 1: Nichtopioide]" [Drugs for postoperative analgesia: routine and new aspects. Part 1: non-opioids]. Der Anaesthesist (in German). 57 (4): 382–390. doi:10.1007/s00101-008-1326-x. PMID 18351305. S2CID 32814418.
Brack A, Rittner HL, Schäfer M (March 2004). "Nichtopioidanalgetika zur perioperativen Schmerztherapie" [Non-opioid analgesics for perioperative pain therapy. Risks and rational basis for use]. Der Anaesthesist (in German). 53 (3): 263–280. doi:10.1007/s00101-003-0641-5. PMID 15021958. S2CID 8829564.
Petkova V, Valchanova V, Ibrahim A, Nikolova I, Benbasat N, Dimitrov M (March 2014). "Marketing approaches for OTC analgesics in Bulgaria". Biotechnology, Biotechnological Equipment. 28 (2): 360–365. doi:10.1080/13102818.2014.911477. PMC 4433822. PMID 26019521.
Lutz M (November 2019). "Metamizole (Dipyrone) and the Liver: A Review of the Literature". Journal of Clinical Pharmacology. 59 (11): 1433–1442. doi:10.1002/jcph.1512. PMID 31433499. S2CID 201118022.
Sznejder H, Amand C, Stewart A, Salazar R, Scala WA (2022). "Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients". Einstein. 20. Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein: eAO6353. doi:10.31744/einstein_journal/2022ao6353. PMC 9060643. PMID 35584441.
Lampl C, Likar R (December 2014). "[Metamizole (dipyrone): mode of action, drug-drug interactions, and risk of agranulocytosis]". Schmerz (in German). 28 (6): 584–90. doi:10.1007/s00482-014-1490-7. PMID 25199942.
Collares EF, Troncon LE (January 2019). "Effects of dipyrone on the digestive tract". Braz J Med Biol Res. 52 (2): e8103. doi:10.1590/1414-431X20188103. PMC 6328969. PMID 30652827.
Jasiecka A, Maślanka T, Jaroszewski JJ (2014). "Pharmacological characteristics of metamizole". Polish Journal of Veterinary Sciences. 17 (1): 207–214. doi:10.2478/pjvs-2014-0030. PMID 24724493.
Pogatzki-Zahn E, Chandrasena C, Schug SA (October 2014). "Nonopioid analgesics for postoperative pain management". Current Opinion in Anesthesiology. 27 (5): 513–519. doi:10.1097/ACO.0000000000000113. PMID 25102238. S2CID 31337982.
García-Martín E, Esguevillas G, Blanca-López N, García-Menaya J, Blanca M, Amo G, et al. (September 2015). "Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis". Pharmacogenetics and Genomics. 25 (9): 462–464. doi:10.1097/FPC.0000000000000157. PMID 26111152.
Mérida Rodrigo L, Faus Felipe V, Poveda Gómez F, García Alegría J (April 2009). "Agranulocitosis por metamizol: un potencial problema en la población británica" [Agranulocytosis from metamizole: a potential problem for the British population]. Revista Clínica Española (in Spanish). 209 (4): 176–179. doi:10.1016/s0014-2565(09)71310-4. PMID 19457324.
Kötter T, da Costa BR, Fässler M, Blozik E, Linde K, Jüni P, et al. (13 April 2015). "Metamizole-associated adverse events: a systematic review and meta-analysis". PLOS ONE. 10 (4). Public Library of Science (PLoS): e0122918. Bibcode:2015PLoSO..1022918K. doi:10.1371/journal.pone.0122918. PMC 4405027. PMID 25875821.
Andrade S, Bartels DB, Lange R, Sandford L, Gurwitz J (October 2016). "Safety of metamizole: a systematic review of the literature". Journal of Clinical Pharmacy and Therapeutics. 41 (5): 459–477. doi:10.1111/jcpt.12422. PMID 27422768. S2CID 24538147.
Lutz M (November 2019). "Metamizole (Dipyrone) and the Liver: A Review of the Literature". J Clin Pharmacol. 59 (11): 1433–1442. doi:10.1002/jcph.1512. PMID 31433499.
Schmelzer KP, Liebetrau D, Kämmerer W, Meisinger C, Hyhlik-Dürr A (April 2023). "Strategies for Avoiding Typical Drug-Drug Interactions and Drug-Related Problems in Patients with Vascular Diseases". Medicina (Kaunas). 59 (4): 780. doi:10.3390/medicina59040780. PMC 10142821. PMID 37109738. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Monteiro B, Steagall PV (November 2019). "Antiinflammatory Drugs". The Veterinary Clinics of North America. Small Animal Practice. 49 (6): 993–1011. doi:10.1016/j.cvsm.2019.07.009. PMID 31519356. Metamizole (dipyrone) is considered an atypical NSAID with weak antiinflammatory properties, but potent analgesic effects that are thought to be related mainly via central inhibition of COX-3 enzyme
Bachmann F, Duthaler U, Rudin D, Krähenbühl S, Haschke M (July 2018). "N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole". European Journal of Pharmaceutical Sciences. 120: 172–180. doi:10.1016/j.ejps.2018.05.003. PMID 29746911.
Lupu G, Bel L, Andrei S (November 2022). "Pain Management and Analgesics Used in Small Mammals during Post-Operative Period with an Emphasis on Metamizole (Dipyrone) as an Alternative Medication". Molecules. 27 (21): 7434. doi:10.3390/molecules27217434. PMC 9657641. PMID 36364259.
Crunfli F, Vilela FC, Giusti-Paiva A (March 2015). "Cannabinoid CB1 receptors mediate the effects of dipyrone". Clinical and Experimental Pharmacology & Physiology. 42 (3): 246–255. doi:10.1111/1440-1681.12347. PMID 25430877. S2CID 13598808.
Gonçalves Dos Santos G, Vieira WF, Vendramini PH, Bassani da Silva B, Fernandes Magalhães S, Tambeli CH, et al. (May 2020). "Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB₂ and kappa-opioid receptors activation". European Journal of Pharmacology. 874: 173005. doi:10.1016/j.ejphar.2020.173005. PMID 32057719. S2CID 211112059.
Malvar D, Aguiar FA, Vaz A, Assis DC, de Melo MC, Jabor VA, et al. (August 2014). "Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever". British Journal of Pharmacology. 171 (15): 3666–3679. doi:10.1111/bph.12717. PMC 4128064. PMID 24712707.
Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, et al. (January 2012). "Novel bioactive metabolites of dipyrone (metamizol)". Bioorganic & Medicinal Chemistry. 20 (1): 101–107. doi:10.1016/j.bmc.2011.11.028. PMC 3248997. PMID 22172309.
Bhaumik S (July 2013). "India's health ministry bans pioglitazone, metamizole, and flupentixol-melitracen". BMJ. 347: f4366. doi:10.1136/bmj.f4366. PMID 23833116. S2CID 45107003.
Bonkowsky JL, Frazer JK, Buchi KF, Byington CL (June 2002). "Metamizole use by Latino immigrants: a common and potentially harmful home remedy". Pediatrics. 109 (6): e98. doi:10.1542/peds.109.6.e98. PMID 12042592. Archived from the original on 2024-03-15. Retrieved 2024-03-15.
Garcia S, Canoniero M, Lopes G, Soriano AO (September 2006). "Metamizole use among Hispanics in Miami: report of a survey conducted in a primary care setting". Southern Medical Journal. 99 (9): 924–926. doi:10.1097/01.smj.0000233020.68212.8f. PMID 17004525. S2CID 41638378.
Taylor L, Abarca S, Henry B, Friedman L (September 2001). "Use of Neo-melubrina, a banned antipyretic drug, in San Diego, California: a survey of patients and providers". The Western Journal of Medicine. 175 (3): 159–163. doi:10.1136/ewjm.175.3.159. PMC 1071527. PMID 11527837.
Preissner S, Siramshetty VB, Dunkel M, Steinborn P, Luft FC, Preissner R (2019). "Pain-Prescription Differences - An Analysis of 500,000 Discharge Summaries". Current Drug Research Reviews. 11 (1): 58–66. doi:10.2174/1874473711666180911091846. PMID 30207223. S2CID 52192130.
Dinavitser N (January 2020). "Dipyrone – a Good Medication with a Bad Reputation". Journal of Medical Toxicology. 16 (1). Rambam Health Care Campus, Haifa, Israel: American College of Medical Toxicology: 75–86. doi:10.1007/s13181-019-00743-w. PMC 6942089. PMID 31721040. ACMT/IST 2019 American-Israeli Medical Toxicology Conference
Aragão RB, Semensatto D, Calixto LA, Labuto G (2020). "Pharmaceutical market, environmental public policies and water quality: the case of the São Paulo Metropolitan Region, Brazil". Cadernos de Saúde Pública. 36 (11): e00192319. doi:10.1590/0102-311x00192319. ISSN 1678-4464. PMID 33237204. S2CID 227168554.

ncbi.nlm.nih.gov

Petkova V, Valchanova V, Ibrahim A, Nikolova I, Benbasat N, Dimitrov M (March 2014). "Marketing approaches for OTC analgesics in Bulgaria". Biotechnology, Biotechnological Equipment. 28 (2): 360–365. doi:10.1080/13102818.2014.911477. PMC 4433822. PMID 26019521.
Sznejder H, Amand C, Stewart A, Salazar R, Scala WA (2022). "Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients". Einstein. 20. Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein: eAO6353. doi:10.31744/einstein_journal/2022ao6353. PMC 9060643. PMID 35584441.
Collares EF, Troncon LE (January 2019). "Effects of dipyrone on the digestive tract". Braz J Med Biol Res. 52 (2): e8103. doi:10.1590/1414-431X20188103. PMC 6328969. PMID 30652827.
Kötter T, da Costa BR, Fässler M, Blozik E, Linde K, Jüni P, et al. (13 April 2015). "Metamizole-associated adverse events: a systematic review and meta-analysis". PLOS ONE. 10 (4). Public Library of Science (PLoS): e0122918. Bibcode:2015PLoSO..1022918K. doi:10.1371/journal.pone.0122918. PMC 4405027. PMID 25875821.
Schmelzer KP, Liebetrau D, Kämmerer W, Meisinger C, Hyhlik-Dürr A (April 2023). "Strategies for Avoiding Typical Drug-Drug Interactions and Drug-Related Problems in Patients with Vascular Diseases". Medicina (Kaunas). 59 (4): 780. doi:10.3390/medicina59040780. PMC 10142821. PMID 37109738. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Lupu G, Bel L, Andrei S (November 2022). "Pain Management and Analgesics Used in Small Mammals during Post-Operative Period with an Emphasis on Metamizole (Dipyrone) as an Alternative Medication". Molecules. 27 (21): 7434. doi:10.3390/molecules27217434. PMC 9657641. PMID 36364259.
Malvar D, Aguiar FA, Vaz A, Assis DC, de Melo MC, Jabor VA, et al. (August 2014). "Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever". British Journal of Pharmacology. 171 (15): 3666–3679. doi:10.1111/bph.12717. PMC 4128064. PMID 24712707.
Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, et al. (January 2012). "Novel bioactive metabolites of dipyrone (metamizol)". Bioorganic & Medicinal Chemistry. 20 (1): 101–107. doi:10.1016/j.bmc.2011.11.028. PMC 3248997. PMID 22172309.
Taylor L, Abarca S, Henry B, Friedman L (September 2001). "Use of Neo-melubrina, a banned antipyretic drug, in San Diego, California: a survey of patients and providers". The Western Journal of Medicine. 175 (3): 159–163. doi:10.1136/ewjm.175.3.159. PMC 1071527. PMID 11527837.
Dinavitser N (January 2020). "Dipyrone – a Good Medication with a Bad Reputation". Journal of Medical Toxicology. 16 (1). Rambam Health Care Campus, Haifa, Israel: American College of Medical Toxicology: 75–86. doi:10.1007/s13181-019-00743-w. PMC 6942089. PMID 31721040. ACMT/IST 2019 American-Israeli Medical Toxicology Conference

nihs.go.jp

jpdb.nihs.go.jp

Pharmaceutical and Medical Device Regulatory Science Society of Japan (2022). The Japanese Pharmacopoeia (PDF) (18th English ed.). Yakuji Nippo-sha. p. 1760. ISBN 978-4-8408-1589-5. Archived (PDF) from the original on 2023-01-20. Retrieved 2023-08-14.

nobelprize.org

"Emil Fischer – Biographical". Nobel Committee. Archived from the original on 2017-06-06. Retrieved 2017-06-14.

planetayurveda.com

Ministry of Health and Family Welfare (2007). Indian Pharmacopeia (PDF). Vol. 2. Ghaziabad, India: Indian Pharmacopoeia Commission. p. 117. Archived (PDF) from the original on 2023-07-28. Retrieved 2023-08-13.

rsdjournal.org

Reis SL, Batista AP, Assumpção J, Ramos ER, Colacite J, Souza LF (2022-10-09). "A bibliographic analysis on the use of Dipyrone and Agranulocytosis". Research, Society and Development. 11 (13): e369111335570. doi:10.33448/rsd-v11i13.35570. S2CID 252870061. Archived from the original on 2023-07-19. Retrieved 2023-07-19.

semanticscholar.org

api.semanticscholar.org

Jage J, Laufenberg-Feldmann R, Heid F (April 2008). "[Medikamente zur postoperativen Schmerztherapie: Bewährtes und Neues. Teil 1: Nichtopioide]" [Drugs for postoperative analgesia: routine and new aspects. Part 1: non-opioids]. Der Anaesthesist (in German). 57 (4): 382–390. doi:10.1007/s00101-008-1326-x. PMID 18351305. S2CID 32814418.
Brack A, Rittner HL, Schäfer M (March 2004). "Nichtopioidanalgetika zur perioperativen Schmerztherapie" [Non-opioid analgesics for perioperative pain therapy. Risks and rational basis for use]. Der Anaesthesist (in German). 53 (3): 263–280. doi:10.1007/s00101-003-0641-5. PMID 15021958. S2CID 8829564.
Lutz M (November 2019). "Metamizole (Dipyrone) and the Liver: A Review of the Literature". Journal of Clinical Pharmacology. 59 (11): 1433–1442. doi:10.1002/jcph.1512. PMID 31433499. S2CID 201118022.
Nikolova I, Tencheva J, Voinikov J, Petkova V, Benbasat N, Danchev N (2014). "Metamizole: A Review Profile of a Well-Known "Forgotten" Drug. Part I: Pharmaceutical and Nonclinical Profile". Biotechnology & Biotechnological Equipment. 26 (6): 3329–3337. doi:10.5504/BBEQ.2012.0089. ISSN 1310-2818. S2CID 56205439.
Pogatzki-Zahn E, Chandrasena C, Schug SA (October 2014). "Nonopioid analgesics for postoperative pain management". Current Opinion in Anesthesiology. 27 (5): 513–519. doi:10.1097/ACO.0000000000000113. PMID 25102238. S2CID 31337982.
Reis SL, Batista AP, Assumpção J, Ramos ER, Colacite J, Souza LF (2022-10-09). "A bibliographic analysis on the use of Dipyrone and Agranulocytosis". Research, Society and Development. 11 (13): e369111335570. doi:10.33448/rsd-v11i13.35570. S2CID 252870061. Archived from the original on 2023-07-19. Retrieved 2023-07-19.
Andrade S, Bartels DB, Lange R, Sandford L, Gurwitz J (October 2016). "Safety of metamizole: a systematic review of the literature". Journal of Clinical Pharmacy and Therapeutics. 41 (5): 459–477. doi:10.1111/jcpt.12422. PMID 27422768. S2CID 24538147.
Crunfli F, Vilela FC, Giusti-Paiva A (March 2015). "Cannabinoid CB1 receptors mediate the effects of dipyrone". Clinical and Experimental Pharmacology & Physiology. 42 (3): 246–255. doi:10.1111/1440-1681.12347. PMID 25430877. S2CID 13598808.
Gonçalves Dos Santos G, Vieira WF, Vendramini PH, Bassani da Silva B, Fernandes Magalhães S, Tambeli CH, et al. (May 2020). "Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB₂ and kappa-opioid receptors activation". European Journal of Pharmacology. 874: 173005. doi:10.1016/j.ejphar.2020.173005. PMID 32057719. S2CID 211112059.
Bhaumik S (July 2013). "India's health ministry bans pioglitazone, metamizole, and flupentixol-melitracen". BMJ. 347: f4366. doi:10.1136/bmj.f4366. PMID 23833116. S2CID 45107003.
Garcia S, Canoniero M, Lopes G, Soriano AO (September 2006). "Metamizole use among Hispanics in Miami: report of a survey conducted in a primary care setting". Southern Medical Journal. 99 (9): 924–926. doi:10.1097/01.smj.0000233020.68212.8f. PMID 17004525. S2CID 41638378.
Preissner S, Siramshetty VB, Dunkel M, Steinborn P, Luft FC, Preissner R (2019). "Pain-Prescription Differences - An Analysis of 500,000 Discharge Summaries". Current Drug Research Reviews. 11 (1): 58–66. doi:10.2174/1874473711666180911091846. PMID 30207223. S2CID 52192130.
Aragão RB, Semensatto D, Calixto LA, Labuto G (2020). "Pharmaceutical market, environmental public policies and water quality: the case of the São Paulo Metropolitan Region, Brazil". Cadernos de Saúde Pública. 36 (11): e00192319. doi:10.1590/0102-311x00192319. ISSN 1678-4464. PMID 33237204. S2CID 227168554.

theolivepress.es

"Exclusive: southern spain hospitals in british expat hotspot issue warning for 'lethal' painkiller nolotil". 23 April 2018. Archived from the original on 28 April 2018. Retrieved 27 April 2018.

ugm.ac.id

jurnal.ugm.ac.id

Kurniawati M, Ikawati Z, Raharjo B (2012). "The evaluation of metamizole use in some places of pharmacy service in Cilacap county". Jurnal Manajemen Dan Pelayanan Farmasi (Journal of Management and Pharmacy Practice) (in Indonesian). 2 (1): 50–55. Archived from the original on 7 April 2023. Retrieved 15 March 2022.

un.org

United Nations Department of Economic and Social Affairs (2005). Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted of Not Approved by Governments (PDF) (12th ed.). New York: United Nations. pp. 171–5. Archived (PDF) from the original on 21 April 2021. Retrieved 3 April 2013.
Department of Economic and Social Affairs of the United Nations Secretariat Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Fourteenth Issue (New data only) (January 2005 – October 2008): Pharmaceuticals Archived 2017-03-09 at the Wayback Machine United Nations – New York, 2009

web.archive.org

"Metamizole Annex I - List of nationally authorised medicinal products" (PDF). European Medicines Agency. 2018-06-01. Archived (PDF) from the original on 2022-02-05. Retrieved 2023-08-14.
"Fachinformation (Zusammenfassung der Merkmale des Arzneimittels) Novaminsulfon injekt 1000 mg Lichtenstein Novaminsulfon injekt 2500 mg Lichtenstein" (PDF). Winthrop Arzneimittel GmbH (in German). Zinteva Pharm GmbH. February 2013. Archived (PDF) from the original on 16 October 2018. Retrieved 19 April 2014.
"Notice of Amendment: Addition of Metamizole (Dipyrone) to the Prescription Drug List (PDL)". Government of Canada. 2022-07-18. Archived from the original on 2022-08-30. Retrieved 2023-08-04.
"Recent NZ Gazette Notices Relating to Classification". medsafe.govt.nz. 2020-03-06. Archived from the original on 2023-04-29. Retrieved 2023-08-04.
"Minutes of the 63rd meeting of the Medicines Classification Committee - 10 Oct 2019". medsafe.govt.nz. 2019-12-04. Archived from the original on 2023-06-10. Retrieved 2023-08-04.
FDA's Center for Veterinary Medicine (November 26, 2019). "Zimeta (dipyrone injection) - Veterinarians". FDA. Archived from the original on 2022-01-17. Retrieved 2023-08-04.
European Medicines Agency (2018-09-17). "Metamizole containing medicinal products - EMA recommends aligning doses of metamizole medicines and their use during pregnancy and breastfeeding". European Medicines Agency. Archived from the original on 2023-02-01. Retrieved 2023-08-04.
- CHMP (2018-12-13). "Metamizole - Assessment report" (PDF). European Medicines Agency (published 2019-03-28). Archived (PDF) from the original on 2022-02-05. Retrieved 2023-08-03.
- "Risikoinformationen - Metamizol (Novalgin, Berlosin, Novaminsulfon, etc.): BfArM weist auf richtige Indikationsstellung und Beachtung von Vorsichtsmaßnahmen und Warnhinweisen hin" [Risk information - Metamizol (Novalgin, Berlosin, Novaminsulfon, etc.): BfArM points out the correct indication and compliance with precautionary measures and warnings]. Bundesinstitut für Arzneimittel und Medizinprodukte (Federal Institute for Pharmaceuticals and Medical Products). 2009-05-28. Archived from the original on 2023-05-18. Retrieved 2023-08-04.
- "Fachinformation (Zusammenfassung der Merkmale des Arzneimittels) Novaminsulfon injekt 1000 mg Lichtenstein Novaminsulfon injekt 2500 mg Lichtenstein" (PDF). Winthrop Arzneimittel GmbH (in German). Zinteva Pharm GmbH. February 2013. Archived (PDF) from the original on 16 October 2018. Retrieved 19 April 2014.
- "Govt lifts ban on painkiller Analgin". Business Standard India. 19 March 2014. Archived from the original on 7 January 2018. Retrieved 7 January 2018.
- United Nations Department of Economic and Social Affairs (2005). Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted of Not Approved by Governments (PDF) (12th ed.). New York: United Nations. pp. 171–5. Archived (PDF) from the original on 21 April 2021. Retrieved 3 April 2013.
- Reis SL, Batista AP, Assumpção J, Ramos ER, Colacite J, Souza LF (2022-10-09). "A bibliographic analysis on the use of Dipyrone and Agranulocytosis". Research, Society and Development. 11 (13): e369111335570. doi:10.33448/rsd-v11i13.35570. S2CID 252870061. Archived from the original on 2023-07-19. Retrieved 2023-07-19.
- Assessment report: metamizole-containing medicinal products (PDF) (Report). European Medicines Agency, Committee for Medicinal Products for Human Use (CHMP). 13 December 2018. EMA/143912/2019. Archived (PDF) from the original on 5 February 2022. Retrieved 4 August 2023.
- "Emil Fischer – Biographical". Nobel Committee. Archived from the original on 2017-06-06. Retrieved 2017-06-14.
- Department of Economic and Social Affairs of the United Nations Secretariat Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Fourteenth Issue (New data only) (January 2005 – October 2008): Pharmaceuticals Archived 2017-03-09 at the Wayback Machine United Nations – New York, 2009
- Gardner S (1977-06-07). Drug products containing dipyrone - Withdrawal of Approval of New Drug Applications (Report). Vol. 42. Federal Register (published 1977-06-17). pp. 30893–4. ISSN 0097-6326. Archived from the original on 2020-09-29. Retrieved 2023-08-04. This notice withdraws approval of the new drug applications (NDA's) for drug products containing dipyrone. The drug products have been used to reduce fever, but they are not shown to be safe for use. On the basis of new evidence, not contained in the applications or not available until after the applications were approved, evaluated together with the evidence available when the applications were approved, the Commissioner of Food and Drugs finds that such drugs have not been shown to be safe for use upon the basis of which the applications were approved. (...) approval of the NDA's providing for the drug products named above, and all amendments and supplements applying thereto, is withdrawn effective June 27,1977. Shipment in interstate commerce of the above-listed products or of any identical, related, or similar product, not the subject of an approved NDA, will then be unlawful.
- Panda AK (2014-02-13). Drugs Rules - G.S.R. 86(E) 13.02.2014 Revoke GSR378(E) Reg. Suspension of Analgin (PDF) (Report). New Delhi: The Gazette of India. Archived (PDF) from the original on 2023-08-11. Retrieved 2023-08-11.
- Bonkowsky JL, Frazer JK, Buchi KF, Byington CL (June 2002). "Metamizole use by Latino immigrants: a common and potentially harmful home remedy". Pediatrics. 109 (6): e98. doi:10.1542/peds.109.6.e98. PMID 12042592. Archived from the original on 2024-03-15. Retrieved 2024-03-15.
- Brazilian Health Regulatory Agency (ANVISA) (24 July 2001). Painel Internacional de Avaliação da Segurança da Dipirona [International Panel for the Evaluation of Dipyrone Safety] (PDF) (Report) (in Portuguese). Brasília. Archived from the original (PDF) on 2009-01-21.
- Biernath A (2023-08-17). "Dipirona: por que é vendida no Brasil, mas proibida nos EUA e em parte da Europa?". BBC News Brasil (in Brazilian Portuguese). Archived from the original on 2023-10-14. Retrieved 2023-09-21.
- Kurniawati M, Ikawati Z, Raharjo B (2012). "The evaluation of metamizole use in some places of pharmacy service in Cilacap county". Jurnal Manajemen Dan Pelayanan Farmasi (Journal of Management and Pharmacy Practice) (in Indonesian). 2 (1): 50–55. Archived from the original on 7 April 2023. Retrieved 15 March 2022.
- "Exclusive: southern spain hospitals in british expat hotspot issue warning for 'lethal' painkiller nolotil". 23 April 2018. Archived from the original on 28 April 2018. Retrieved 27 April 2018.
- Kim CH (2004-08-26). "해열진통제 '설피린' 국내사용 논란" [Controversy over domestic use of antipyretic analgesic Sulpyrin]. 경기신문 [kgnews] (in Korean). Archived from the original on 2023-08-14. Retrieved 2023-08-14.
- Pharmaceutical and Medical Device Regulatory Science Society of Japan (2022). The Japanese Pharmacopoeia (PDF) (18th English ed.). Yakuji Nippo-sha. p. 1760. ISBN 978-4-8408-1589-5. Archived (PDF) from the original on 2023-01-20. Retrieved 2023-08-14.
- Ovchinnikov R (2011-12-22). "Анальгин хотят отпустить в одни руки" [Analgin want to let go in one hand]. Известия (in Russian). Archived from the original on 2023-08-12.
- "Pavel Sadovsky comments on trademarks registering for RIA Novosti - Insights". EPAM Law. 2012-02-22. Archived from the original on 2021-02-25. Retrieved 2023-08-14.
- "Sopharma wins TM battle over analgesic drug Analgin". FFBH. 2004-08-05. Archived from the original on 2023-08-14. Retrieved 2023-08-14.
- Ministry of Health and Family Welfare (2007). Indian Pharmacopeia (PDF). Vol. 2. Ghaziabad, India: Indian Pharmacopoeia Commission. p. 117. Archived (PDF) from the original on 2023-07-28. Retrieved 2023-08-13.

worldcat.org

Nikolova I, Tencheva J, Voinikov J, Petkova V, Benbasat N, Danchev N (2014). "Metamizole: A Review Profile of a Well-Known "Forgotten" Drug. Part I: Pharmaceutical and Nonclinical Profile". Biotechnology & Biotechnological Equipment. 26 (6): 3329–3337. doi:10.5504/BBEQ.2012.0089. ISSN 1310-2818. S2CID 56205439.
Aronson JK, ed. (2015). Meyler's side effects of drugs: the international encyclopedia of adverse drug reactions and interactions. Vol. 4 (16th ed.). Amsterdam Boston Heidelberg: Elsevier. pp. 859–862. ISBN 978-0-444-53716-4. OCLC 927102885.
Gardner S (1977-06-07). Drug products containing dipyrone - Withdrawal of Approval of New Drug Applications (Report). Vol. 42. Federal Register (published 1977-06-17). pp. 30893–4. ISSN 0097-6326. Archived from the original on 2020-09-29. Retrieved 2023-08-04. This notice withdraws approval of the new drug applications (NDA's) for drug products containing dipyrone. The drug products have been used to reduce fever, but they are not shown to be safe for use. On the basis of new evidence, not contained in the applications or not available until after the applications were approved, evaluated together with the evidence available when the applications were approved, the Commissioner of Food and Drugs finds that such drugs have not been shown to be safe for use upon the basis of which the applications were approved. (...) approval of the NDA's providing for the drug products named above, and all amendments and supplements applying thereto, is withdrawn effective June 27,1977. Shipment in interstate commerce of the above-listed products or of any identical, related, or similar product, not the subject of an approved NDA, will then be unlawful.
Aragão RB, Semensatto D, Calixto LA, Labuto G (2020). "Pharmaceutical market, environmental public policies and water quality: the case of the São Paulo Metropolitan Region, Brazil". Cadernos de Saúde Pública. 36 (11): e00192319. doi:10.1590/0102-311x00192319. ISSN 1678-4464. PMID 33237204. S2CID 227168554.

zentiva.de

"Fachinformation (Zusammenfassung der Merkmale des Arzneimittels) Novaminsulfon injekt 1000 mg Lichtenstein Novaminsulfon injekt 2500 mg Lichtenstein" (PDF). Winthrop Arzneimittel GmbH (in German). Zinteva Pharm GmbH. February 2013. Archived (PDF) from the original on 16 October 2018. Retrieved 19 April 2014.
"Fachinformation (Zusammenfassung der Merkmale des Arzneimittels) Novaminsulfon injekt 1000 mg Lichtenstein Novaminsulfon injekt 2500 mg Lichtenstein" (PDF). Winthrop Arzneimittel GmbH (in German). Zinteva Pharm GmbH. February 2013. Archived (PDF) from the original on 16 October 2018. Retrieved 19 April 2014.