Methoxyflurane (English Wikipedia)

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Jephcott C, Grummet J, Nguyen N, Spruyt O (May 2018). "A review of the safety and efficacy of inhaled methoxyflurane as an analgesic for outpatient procedures". British Journal of Anaesthesia. 120 (5): 1040–1048. doi:10.1016/j.bja.2018.01.011. PMID 29661381.
Mazze RI (October 2006). "Methoxyflurane revisited: tale of an anesthetic from cradle to grave". Anesthesiology. 105 (4): 843–846. doi:10.1097/00000542-200610000-00031. PMID 17006084.
Babl FE, Jamison SR, Spicer M, Bernard S (August 2006). "Inhaled methoxyflurane as a prehospital analgesic in children". Emergency Medicine Australasia. 18 (4): 404–410. doi:10.1111/j.1742-6723.2006.00874.x. PMID 16842312. S2CID 1619160.
Grindlay J, Babl FE (February 2009). "Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting". Emergency Medicine Australasia. 21 (1): 4–11. doi:10.1111/j.1742-6723.2009.01153.x. PMID 19254307. S2CID 40158248.
McLennan JV (June 2007). "Is methoxyflurane a suitable battlefield analgesic?" (PDF). Journal of the Royal Army Medical Corps. 153 (2): 111–113. doi:10.1136/jramc-153-02-08. PMID 17896540. S2CID 38517296. Archived from the original (PDF) on 15 July 2011.
Babl F, Barnett P, Palmer G, Oakley E, Davidson A (February 2007). "A pilot study of inhaled methoxyflurane for procedural analgesia in children". Pediatric Anesthesia. 17 (2): 148–153. doi:10.1111/j.1460-9592.2006.02037.x. PMID 17238886. S2CID 30105092.
Cousins MJ, Mazze RI (September 1973). "Methoxyflurane nephrotoxicity. A study of dose response in man". JAMA. 225 (13): 1611–1616. doi:10.1001/jama.1973.03220410023005. PMID 4740737.
Gottlieb LS, Trey C (1974). "The effects of fluorinated anesthetics on the liver and kidneys". Annual Review of Medicine. 25: 411–429. doi:10.1146/annurev.me.25.020174.002211. PMID 4596236.
Crandell WB, Pappas SG, Macdonald A (1966). "Nephrotoxicity associated with methoxyflurane anesthesia". Anesthesiology. 27 (5): 591–607. doi:10.1097/00000542-196609000-00010. PMID 5918999. S2CID 39661400.
Klein NC, Jeffries GH (September 1966). "Hepatotoxicity after methoxyflurane administration". JAMA. 197 (12): 1037–1039. doi:10.1001/jama.1966.03110120143040. PMID 5953207.
Jones NO (March 1972). "Methoxyflurane nephrotoxicity--a review and a case report". Canadian Anaesthetists' Society Journal. 19 (2): 152–159. doi:10.1007/BF03005045. PMID 5029469.
Mazze RI (June 1976). "Methoxyflurane nephropathy". Environmental Health Perspectives. 15: 111–119. Bibcode:1976EnvHP..15..111M. doi:10.1289/ehp.7615111. JSTOR 3428393. PMC 1475154. PMID 1001288.
Kharasch ED, Schroeder JL, Liggitt HD, Park SB, Whittington D, Sheffels P (October 2006). "New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway". Anesthesiology. 105 (4): 726–736. doi:10.1097/00000542-200610000-00019. PMID 17006072. S2CID 25900511.
Kharasch ED, Schroeder JL, Liggitt HD, Ensign D, Whittington D (October 2006). "New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 2): Identification of nephrotoxic metabolites". Anesthesiology. 105 (4): 737–745. doi:10.1097/00000542-200610000-00020. PMID 17006073. S2CID 21609274.
Wyant GM, Chang CA, Rapicavoli E (September 1961). "Methoxyflurane (penthrane): a laboratory and clinical study". Canadian Anaesthetists' Society Journal. 8 (5): 477–487. doi:10.1007/BF03021373. PMID 13786945.
Siebecker KL, James M, Bamforth BJ, Orth OS (1961). "The respiratory effect of methoxyflurane on dog and man". Anesthesiology. 22 (1): 143. doi:10.1097/00000542-196101000-00044.
Millar RA, Morris ME (May 1961). "A study of methoxyflurane anaesthesia". Canadian Anaesthetists' Society Journal. 8 (3): 210–215. doi:10.1007/BF03028110. PMID 13770698.
Artusio JF, Van Poznak A, Hunt RE, Tiers RM, Alexander M (1960). "A clinical evaluation of methoxyflurane in man". Anesthesiology. 21 (5): 512–517. doi:10.1097/00000542-196009000-00009. PMID 13794589. S2CID 45338415.
Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. I. Fluorinated hydrocarbons". Toxicology and Applied Pharmacology. 2 (4): 363–373. Bibcode:1960ToxAP...2..363P. doi:10.1016/0041-008X(60)90002-8. PMID 13841124.
Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. II. Fluorinated ethers". Toxicology and Applied Pharmacology. 2 (4): 374–378. Bibcode:1960ToxAP...2..374V. doi:10.1016/0041-008X(60)90003-X. PMID 13841125.
Buntine P, Thom O, Babl F, Bailey M, Bernard S (December 2007). "Prehospital analgesia in adults using inhaled methoxyflurane". Emergency Medicine Australasia. 19 (6): 509–514. doi:10.1111/j.1742-6723.2007.01017.x. PMID 18021102. S2CID 11260623.
Johnston S, Wilkes GJ, Thompson JA, Ziman M, Brightwell R (January 2011). "Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service". Emergency Medicine Journal. 28 (1): 57–63. doi:10.1136/emj.2009.078717. PMID 20466829. S2CID 24955345.
Major V, Rosen M, Mushin WW (December 1966). "Methoxyflurane as an obstetric analgesic: a comparison with trichloroethylene". British Medical Journal. 2 (5529): 1554–1561. doi:10.1136/bmj.2.5529.1554. PMC 1944957. PMID 5926260.
Dragon A, Goldstein I (November 1967). "Methoxyflurane: preliminary report on analgesic and mood-modifying properties in dentistry". Journal of the American Dental Association. 75 (5): 1176–1181. doi:10.14219/jada.archive.1967.0358. PMID 5233333.
Packer KJ, Titel JH (December 1969). "Methoxyflurane analgesia for burns dressings: experience with the analgizer". British Journal of Anaesthesia. 41 (12): 1080–1085. CiteSeerX 10.1.1.1028.6601. doi:10.1093/bja/41.12.1080. PMID 4903969.
Romagnoli A, Busque L, Power DJ (May 1970). "The "analgizer" in a general hospital: a preliminary report". Canadian Anaesthetists' Society Journal. 17 (3): 275–278. doi:10.1007/BF03004607. PMID 5512851.
Firn S (May 1972). "Methoxyflurane analgesia for burns dressings and other painful ward procedures in children". British Journal of Anaesthesia. 44 (5): 517–522. doi:10.1093/bja/44.5.517. PMID 5044082. S2CID 35308189.
Lewis LA (February 1984). "Methoxyflurane analgesia for office surgery. Surgical gem". The Journal of Dermatologic Surgery and Oncology. 10 (2): 85–86. doi:10.1111/j.1524-4725.1984.tb01191.x. PMID 6693612.
Chin R, McCaskill M, Browne G, Lam L (2002). "A randomised controlled trial of inhaled methoxyflurane pain relief in children with upper limb fracture (abstract)". Journal of Paediatrics and Child Health. 38 (5): A13–4. doi:10.1046/j.1440-1754.2002.00385.x. ISSN 1034-4810.
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Chau PL (September 2010). "New insights into the molecular mechanisms of general anaesthetics". British Journal of Pharmacology. 161 (2): 288–307. doi:10.1111/j.1476-5381.2010.00891.x. PMC 2989583. PMID 20735416.
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Mazze RI, Shue GL, Jackson SH (1971). "Renal Dysfunction Associated With Methoxyflurane Anesthesia". Journal of the American Medical Association. 216 (2): 278–288. doi:10.1001/jama.1971.03180280032006. S2CID 10549698.
Torda TA (July 1963). "The analgesic effect of methoxyflurane". Anaesthesia. 18 (3): 287–289. doi:10.1111/j.1365-2044.1963.tb13548.x. PMID 13981361. S2CID 32905962.
Tomlin PJ, Jones BC, Edwards R, Robin PE (July 1973). "Subjective and objective sensory responses to inhalation of nitrous oxide and methoxyflurane". British Journal of Anaesthesia. 45 (7): 719–725. doi:10.1093/bja/45.7.719. PMID 4730164. S2CID 14379235.
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Dayan AD (January 2016). "Analgesic use of inhaled methoxyflurane: Evaluation of its potential nephrotoxicity". Human & Experimental Toxicology. 35 (1): 91–100. doi:10.1177/0960327115578743. PMID 25926525.

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Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. I. Fluorinated hydrocarbons". Toxicology and Applied Pharmacology. 2 (4): 363–373. Bibcode:1960ToxAP...2..363P. doi:10.1016/0041-008X(60)90002-8. PMID 13841124.
Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. II. Fluorinated ethers". Toxicology and Applied Pharmacology. 2 (4): 374–378. Bibcode:1960ToxAP...2..374V. doi:10.1016/0041-008X(60)90003-X. PMID 13841125.
Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, et al. (September 1997). "Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors". Nature. 389 (6649): 385–389. Bibcode:1997Natur.389..385M. doi:10.1038/38738. PMID 9311780. S2CID 4393717.
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Jephcott C, Grummet J, Nguyen N, Spruyt O (May 2018). "A review of the safety and efficacy of inhaled methoxyflurane as an analgesic for outpatient procedures". British Journal of Anaesthesia. 120 (5): 1040–1048. doi:10.1016/j.bja.2018.01.011. PMID 29661381.
Mazze RI (October 2006). "Methoxyflurane revisited: tale of an anesthetic from cradle to grave". Anesthesiology. 105 (4): 843–846. doi:10.1097/00000542-200610000-00031. PMID 17006084.
Babl FE, Jamison SR, Spicer M, Bernard S (August 2006). "Inhaled methoxyflurane as a prehospital analgesic in children". Emergency Medicine Australasia. 18 (4): 404–410. doi:10.1111/j.1742-6723.2006.00874.x. PMID 16842312. S2CID 1619160.
Grindlay J, Babl FE (February 2009). "Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting". Emergency Medicine Australasia. 21 (1): 4–11. doi:10.1111/j.1742-6723.2009.01153.x. PMID 19254307. S2CID 40158248.
McLennan JV (June 2007). "Is methoxyflurane a suitable battlefield analgesic?" (PDF). Journal of the Royal Army Medical Corps. 153 (2): 111–113. doi:10.1136/jramc-153-02-08. PMID 17896540. S2CID 38517296. Archived from the original (PDF) on 15 July 2011.
Babl F, Barnett P, Palmer G, Oakley E, Davidson A (February 2007). "A pilot study of inhaled methoxyflurane for procedural analgesia in children". Pediatric Anesthesia. 17 (2): 148–153. doi:10.1111/j.1460-9592.2006.02037.x. PMID 17238886. S2CID 30105092.
Cousins MJ, Mazze RI (September 1973). "Methoxyflurane nephrotoxicity. A study of dose response in man". JAMA. 225 (13): 1611–1616. doi:10.1001/jama.1973.03220410023005. PMID 4740737.
Gottlieb LS, Trey C (1974). "The effects of fluorinated anesthetics on the liver and kidneys". Annual Review of Medicine. 25: 411–429. doi:10.1146/annurev.me.25.020174.002211. PMID 4596236.
Paddock RB, Parker JW, Guadagni NP (1964). "The Effects of Methoxyflurane on Renal Function". Anesthesiology. 25: 707–708. PMID 14211499.
Crandell WB, Pappas SG, Macdonald A (1966). "Nephrotoxicity associated with methoxyflurane anesthesia". Anesthesiology. 27 (5): 591–607. doi:10.1097/00000542-196609000-00010. PMID 5918999. S2CID 39661400.
Klein NC, Jeffries GH (September 1966). "Hepatotoxicity after methoxyflurane administration". JAMA. 197 (12): 1037–1039. doi:10.1001/jama.1966.03110120143040. PMID 5953207.
Jones NO (March 1972). "Methoxyflurane nephrotoxicity--a review and a case report". Canadian Anaesthetists' Society Journal. 19 (2): 152–159. doi:10.1007/BF03005045. PMID 5029469.
Mazze RI (June 1976). "Methoxyflurane nephropathy". Environmental Health Perspectives. 15: 111–119. Bibcode:1976EnvHP..15..111M. doi:10.1289/ehp.7615111. JSTOR 3428393. PMC 1475154. PMID 1001288.
Kharasch ED, Schroeder JL, Liggitt HD, Park SB, Whittington D, Sheffels P (October 2006). "New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway". Anesthesiology. 105 (4): 726–736. doi:10.1097/00000542-200610000-00019. PMID 17006072. S2CID 25900511.
Kharasch ED, Schroeder JL, Liggitt HD, Ensign D, Whittington D (October 2006). "New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 2): Identification of nephrotoxic metabolites". Anesthesiology. 105 (4): 737–745. doi:10.1097/00000542-200610000-00020. PMID 17006073. S2CID 21609274.
Wyant GM, Chang CA, Rapicavoli E (September 1961). "Methoxyflurane (penthrane): a laboratory and clinical study". Canadian Anaesthetists' Society Journal. 8 (5): 477–487. doi:10.1007/BF03021373. PMID 13786945.
Millar RA, Morris ME (May 1961). "A study of methoxyflurane anaesthesia". Canadian Anaesthetists' Society Journal. 8 (3): 210–215. doi:10.1007/BF03028110. PMID 13770698.
Artusio JF, Van Poznak A, Hunt RE, Tiers RM, Alexander M (1960). "A clinical evaluation of methoxyflurane in man". Anesthesiology. 21 (5): 512–517. doi:10.1097/00000542-196009000-00009. PMID 13794589. S2CID 45338415.
Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. I. Fluorinated hydrocarbons". Toxicology and Applied Pharmacology. 2 (4): 363–373. Bibcode:1960ToxAP...2..363P. doi:10.1016/0041-008X(60)90002-8. PMID 13841124.
Van Poznak A, Artusio JF (July 1960). "Anesthetic properties of a series of fluorinated compounds. II. Fluorinated ethers". Toxicology and Applied Pharmacology. 2 (4): 374–378. Bibcode:1960ToxAP...2..374V. doi:10.1016/0041-008X(60)90003-X. PMID 13841125.
Buntine P, Thom O, Babl F, Bailey M, Bernard S (December 2007). "Prehospital analgesia in adults using inhaled methoxyflurane". Emergency Medicine Australasia. 19 (6): 509–514. doi:10.1111/j.1742-6723.2007.01017.x. PMID 18021102. S2CID 11260623.
Johnston S, Wilkes GJ, Thompson JA, Ziman M, Brightwell R (January 2011). "Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service". Emergency Medicine Journal. 28 (1): 57–63. doi:10.1136/emj.2009.078717. PMID 20466829. S2CID 24955345.
Major V, Rosen M, Mushin WW (December 1966). "Methoxyflurane as an obstetric analgesic: a comparison with trichloroethylene". British Medical Journal. 2 (5529): 1554–1561. doi:10.1136/bmj.2.5529.1554. PMC 1944957. PMID 5926260.
Dragon A, Goldstein I (November 1967). "Methoxyflurane: preliminary report on analgesic and mood-modifying properties in dentistry". Journal of the American Dental Association. 75 (5): 1176–1181. doi:10.14219/jada.archive.1967.0358. PMID 5233333.
Packer KJ, Titel JH (December 1969). "Methoxyflurane analgesia for burns dressings: experience with the analgizer". British Journal of Anaesthesia. 41 (12): 1080–1085. CiteSeerX 10.1.1.1028.6601. doi:10.1093/bja/41.12.1080. PMID 4903969.
Romagnoli A, Busque L, Power DJ (May 1970). "The "analgizer" in a general hospital: a preliminary report". Canadian Anaesthetists' Society Journal. 17 (3): 275–278. doi:10.1007/BF03004607. PMID 5512851.
Firn S (May 1972). "Methoxyflurane analgesia for burns dressings and other painful ward procedures in children". British Journal of Anaesthesia. 44 (5): 517–522. doi:10.1093/bja/44.5.517. PMID 5044082. S2CID 35308189.
Josephson CA, Schwartz W (February 1974). "The Cardiff inhaler and penthrane. A method of sedation-analgesia in routine dentistry". The Journal of the Dental Association of South Africa = die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika. 29 (2): 77–80. PMID 4534883.
Lewis LA (February 1984). "Methoxyflurane analgesia for office surgery. Surgical gem". The Journal of Dermatologic Surgery and Oncology. 10 (2): 85–86. doi:10.1111/j.1524-4725.1984.tb01191.x. PMID 6693612.
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