NFE2L2 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "NFE2L2" in English language version.

refsWebsite

Global rank English rank

73nih.gov

4^th place

46doi.org

2^nd place

7semanticscholar.org

11^th place

8^th place

6harvard.edu

18^th place

17^th place

2ensembl.org

1,626^th place

1,007^th place

2handle.net

102^nd place

76^th place

1creativecommons.org

1,010^th place

612^th place

1ebi.ac.uk

5,849^th place

7,886^th place

1landesbioscience.com

low place

1newscientist.com

774^th place

716^th place

1web.archive.org

1^st place

1fda.gov

447^th place

338^th place

creativecommons.org

He F, Ru X, Wen T (January 2020). "NRF2, a Transcription Factor for Stress Response and Beyond". International Journal of Molecular Sciences. 21 (13): 4777. doi:10.3390/ijms21134777. PMC 7369905. PMID 32640524. This article incorporates text from this source, which is available under the CC BY 4.0 license.

doi.org

Moi P, Chan K, Asunis I, Cao A, Kan YW (October 1994). "Isolation of NF-E2-related factor 2 (NRF2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9926–9930. Bibcode:1994PNAS...91.9926M. doi:10.1073/pnas.91.21.9926. PMC 44930. PMID 7937919.
Gold R, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, et al. (September 2012). "Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis". The New England Journal of Medicine. 367 (12): 1098–1107. doi:10.1056/NEJMoa1114287. hdl:2078.1/124401. PMID 22992073.
Gureev AP, Popov VN, Starkov AA (2020). "Crosstalk between the mTOR and Nrf2/ARE signaling pathways as a target in the improvement of long-term potentiation". Experimental Neurology. 328: 113285. doi:10.1016/j.expneurol.2020.113285. PMC 7145749. PMID 32165256.
Zhu Y, Yang Q, Liu H, Chen W (2020). "Phytochemical compounds targeting on Nrf2 for chemoprevention in colorectal cancer". European Journal of Pharmacology. 887: 173588. doi:10.1016/j.ejphar.2020.173588. PMID 32961170. S2CID 221863319.
Ahmed S, Luo L, Tang X (2017). "Nrf2 signaling pathway: Pivotal roles in inflammation". Biochimica et Biophysica Acta. Molecular Basis of Disease. 1863 (2): 585–597. doi:10.1016/j.bbadis.2016.11.005. PMID 27825853.
He F, Ru X, Wen T (January 2020). "NRF2, a Transcription Factor for Stress Response and Beyond". International Journal of Molecular Sciences. 21 (13): 4777. doi:10.3390/ijms21134777. PMC 7369905. PMID 32640524. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD (January 2019). "Modulating NRF2 in Disease: Timing Is Everything". Annual Review of Pharmacology and Toxicology. 59: 555–575. doi:10.1146/annurev-pharmtox-010818-021856. PMC 6538038. PMID 30256716.
Chan JY, Cheung MC, Moi P, Chan K, Kan YW (March 1995). "Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization". Human Genetics. 95 (3): 265–269. doi:10.1007/BF00225191. PMID 7868116. S2CID 23774837.
Motohashi H, Yamamoto M (November 2004). "Nrf2-Keap1 defines a physiologically important stress response mechanism". Trends in Molecular Medicine. 10 (11): 549–557. doi:10.1016/j.molmed.2004.09.003. PMID 15519281.
Tonelli C, Chio II, Tuveson DA (December 2018). "Transcriptional Regulation by Nrf2". Antioxidants & Redox Signaling. 29 (17): 1727–1745. doi:10.1089/ars.2017.7342. PMC 6208165. PMID 28899199.
McMahon M, Thomas N, Itoh K, Yamamoto M, Hayes JD (July 2004). "Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron". The Journal of Biological Chemistry. 279 (30): 31556–31567. doi:10.1074/jbc.M403061200. PMID 15143058.
Motohashi H, Katsuoka F, Engel JD, Yamamoto M (April 2004). "Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway". Proceedings of the National Academy of Sciences of the United States of America. 101 (17): 6379–6384. Bibcode:2004PNAS..101.6379M. doi:10.1073/pnas.0305902101. PMC 404053. PMID 15087497.
Nioi P, Nguyen T, Sherratt PJ, Pickett CB (December 2005). "The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation". Molecular and Cellular Biology. 25 (24): 10895–10906. doi:10.1128/MCB.25.24.10895-10906.2005. PMC 1316965. PMID 16314513.
Kopacz A, Rojo AI, Patibandla C, Lastra-Martínez D, Piechota-Polanczyk A, Kloska D, et al. (November 2022). "Overlooked and valuable facts to know in the NRF2/KEAP1 field". Free Radical Biology & Medicine. 192: 37–49. doi:10.1016/j.freeradbiomed.2022.08.044. hdl:10261/289786. PMID 36100148.
Karunatilleke NC, Brickenden A, Choy WY (September 2024). "Molecular basis of the interactions between the disordered Neh4 and Neh5 domains of Nrf2 and CBP/p300 in oxidative stress response". Protein Science. 33 (9): e5137. doi:10.1002/pro.5137. PMC 11328122. PMID 39150085.
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, et al. (January 1999). "Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain". Genes & Development. 13 (1): 76–86. doi:10.1101/gad.13.1.76. PMC 316370. PMID 9887101.
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, et al. (August 2004). "Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2". Molecular and Cellular Biology. 24 (16): 7130–7139. doi:10.1128/MCB.24.16.7130-7139.2004. PMC 479737. PMID 15282312.
Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, et al. (April 2008). "Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity". Molecular and Cellular Biology. 28 (8): 2758–2770. doi:10.1128/MCB.01704-07. PMC 2293100. PMID 18268004.
Sekhar KR, Rachakonda G, Freeman ML (April 2010). "Cysteine-based regulation of the CUL3 adaptor protein Keap1". Toxicology and Applied Pharmacology. 244 (1): 21–26. Bibcode:2010ToxAP.244...21S. doi:10.1016/j.taap.2009.06.016. PMC 2837771. PMID 19560482.
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, et al. (July 1997). "An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements". Biochemical and Biophysical Research Communications. 236 (2): 313–322. doi:10.1006/bbrc.1997.6943. PMID 9240432.
Venugopal R, Jaiswal AK (December 1996). "Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene". Proceedings of the National Academy of Sciences of the United States of America. 93 (25): 14960–14965. Bibcode:1996PNAS...9314960V. doi:10.1073/pnas.93.25.14960. PMC 26245. PMID 8962164.
Solis WA, Dalton TP, Dieter MZ, Freshwater S, Harrer JM, He L, et al. (May 2002). "Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress". Biochemical Pharmacology. 63 (9): 1739–1754. doi:10.1016/S0006-2952(02)00897-3. PMID 12007577.
Neumann CA, Cao J, Manevich Y (December 2009). "Peroxiredoxin 1 and its role in cell signaling" (PDF). Cell Cycle. 8 (24). Georgetown, Tex.: 4072–4078. doi:10.4161/cc.8.24.10242. PMC 7161701. PMID 19923889.
Soriano FX, Baxter P, Murray LM, Sporn MB, Gillingwater TH, Hardingham GE (March 2009). "Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin". Molecules and Cells. 27 (3): 279–282. doi:10.1007/s10059-009-0050-y. PMC 2837916. PMID 19326073.
Jarmi T, Agarwal A (February 2009). "Heme oxygenase and renal disease". Current Hypertension Reports. 11 (1): 56–62. doi:10.1007/s11906-009-0011-z. PMID 19146802. S2CID 36932369.
Wang J, Doré S (June 2007). "Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage". Brain: A Journal of Neurology. 130 (Pt 6): 1643–1652. doi:10.1093/brain/awm095. PMC 2291147. PMID 17525142.
Hayes JD, Chanas SA, Henderson CJ, McMahon M, Sun C, Moffat GJ, et al. (February 2000). "The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin". Biochemical Society Transactions. 28 (2): 33–41. doi:10.1042/bst0280033. PMID 10816095.
Yueh MF, Tukey RH (March 2007). "Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice". The Journal of Biological Chemistry. 282 (12): 8749–8758. doi:10.1074/jbc.M610790200. PMID 17259171.
Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, et al. (November 2007). "Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway". Hepatology. 46 (5). Baltimore, Md.: 1597–1610. doi:10.1002/hep.21831. PMID 17668877. S2CID 19513808.
Reisman SA, Csanaky IL, Aleksunes LM, Klaassen CD (May 2009). "Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice". Toxicological Sciences. 109 (1): 31–40. doi:10.1093/toxsci/kfp047. PMC 2675638. PMID 19246624.
Lee OH, Jain AK, Papusha V, Jaiswal AK (December 2007). "An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance". The Journal of Biological Chemistry. 282 (50): 36412–36420. doi:10.1074/jbc.M706517200. PMID 17925401.
Chorley BN, Campbell MR, Wang X, Karaca M, Sambandan D, Bangura F, et al. (August 2012). "Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha". Nucleic Acids Research. 40 (15): 7416–7429. doi:10.1093/nar/gks409. PMC 3424561. PMID 22581777.
Tian Y, Liu Q, Yu S, Chu Q, Chen Y, Wu K, et al. (October 2020). "NRF2-Driven KEAP1 Transcription in Human Lung Cancer". Molecular Cancer Research. 18 (10): 1465–1476. doi:10.1158/1541-7786.MCR-20-0108. PMID 32571982. S2CID 219989242.
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, et al. (July 2011). "Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis". Nature. 475 (7354): 106–109. doi:10.1038/nature10189. PMC 3404470. PMID 21734707.
Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, et al. (January 2011). "NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection". Arteriosclerosis, Thrombosis, and Vascular Biology. 31 (1): 58–66. doi:10.1161/ATVBAHA.110.210906. PMC 3037185. PMID 20947826.
Araujo JA (2012). "Nrf2 and the promotion of atherosclerosis: lessons to be learned". Clin. Lipidol. 7 (2): 123–126. doi:10.2217/clp.12.5. S2CID 73042634.
Prince M, Li Y, Childers A, Itoh K, Yamamoto M, Kleiner HE (March 2009). "Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice". Toxicology Letters. 185 (3): 180–186. doi:10.1016/j.toxlet.2008.12.014. PMC 2676710. PMID 19150646.
Zhang Y, Gordon GB (July 2004). "A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway". Molecular Cancer Therapeutics. 3 (7): 885–893. doi:10.1158/1535-7163.885.3.7. PMID 15252150.
Velayutham M, Villamena FA, Fishbein JC, Zweier JL (March 2005). "Cancer chemopreventive oltipraz generates superoxide anion radical". Archives of Biochemistry and Biophysics. 435 (1): 83–88. doi:10.1016/j.abb.2004.11.028. PMID 15680910.
Venugopal R, Jaiswal AK (December 1998). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes". Oncogene. 17 (24): 3145–3156. doi:10.1038/sj.onc.1202237. PMID 9872330.
Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M (October 2001). "Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription". Genes to Cells. 6 (10): 857–868. doi:10.1046/j.1365-2443.2001.00469.x. PMID 11683914. S2CID 22999855.
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA (October 2003). "Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival". Molecular and Cellular Biology. 23 (20): 7198–7209. doi:10.1128/MCB.23.20.7198-7209.2003. PMC 230321. PMID 14517290.
Guo Y, Yu S, Zhang C, Kong AN (November 2015). "Epigenetic regulation of Keap1-Nrf2 signaling". Free Radical Biology & Medicine. 88 (Pt B): 337–349. doi:10.1016/j.freeradbiomed.2015.06.013. PMC 4955581. PMID 26117320.
Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, et al. (September 2008). "Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy". Proceedings of the National Academy of Sciences of the United States of America. 105 (36): 13568–13573. Bibcode:2008PNAS..10513568S. doi:10.1073/pnas.0806268105. PMC 2533230. PMID 18757741.
Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD (August 2008). "Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction". Toxicology and Applied Pharmacology. 230 (3): 383–389. Bibcode:2008ToxAP.230..383W. doi:10.1016/j.taap.2008.03.003. PMC 2610481. PMID 18417180.
Patel R, Maru G (June 2008). "Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs". Free Radical Biology & Medicine. 44 (11): 1897–1911. doi:10.1016/j.freeradbiomed.2008.02.006. PMID 18358244.

ebi.ac.uk

"InterPro: Q16236 Nuclear factor erythroid 2-related factor 2". www.ebi.ac.uk.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000116044 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000015839 – Ensembl, May 2017

fda.gov

accessdata.fda.gov

"Dimethyl fumarate label" (PDF). FDA. December 2017. Archived from the original (PDF) on May 16, 2020. Retrieved 19 July 2018. For label updates see FDA index page for NDA 204063

handle.net

hdl.handle.net

Gold R, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, et al. (September 2012). "Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis". The New England Journal of Medicine. 367 (12): 1098–1107. doi:10.1056/NEJMoa1114287. hdl:2078.1/124401. PMID 22992073.
Kopacz A, Rojo AI, Patibandla C, Lastra-Martínez D, Piechota-Polanczyk A, Kloska D, et al. (November 2022). "Overlooked and valuable facts to know in the NRF2/KEAP1 field". Free Radical Biology & Medicine. 192: 37–49. doi:10.1016/j.freeradbiomed.2022.08.044. hdl:10261/289786. PMID 36100148.

harvard.edu

ui.adsabs.harvard.edu

Moi P, Chan K, Asunis I, Cao A, Kan YW (October 1994). "Isolation of NF-E2-related factor 2 (NRF2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9926–9930. Bibcode:1994PNAS...91.9926M. doi:10.1073/pnas.91.21.9926. PMC 44930. PMID 7937919.
Motohashi H, Katsuoka F, Engel JD, Yamamoto M (April 2004). "Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway". Proceedings of the National Academy of Sciences of the United States of America. 101 (17): 6379–6384. Bibcode:2004PNAS..101.6379M. doi:10.1073/pnas.0305902101. PMC 404053. PMID 15087497.
Sekhar KR, Rachakonda G, Freeman ML (April 2010). "Cysteine-based regulation of the CUL3 adaptor protein Keap1". Toxicology and Applied Pharmacology. 244 (1): 21–26. Bibcode:2010ToxAP.244...21S. doi:10.1016/j.taap.2009.06.016. PMC 2837771. PMID 19560482.
Venugopal R, Jaiswal AK (December 1996). "Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene". Proceedings of the National Academy of Sciences of the United States of America. 93 (25): 14960–14965. Bibcode:1996PNAS...9314960V. doi:10.1073/pnas.93.25.14960. PMC 26245. PMID 8962164.
Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, et al. (September 2008). "Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy". Proceedings of the National Academy of Sciences of the United States of America. 105 (36): 13568–13573. Bibcode:2008PNAS..10513568S. doi:10.1073/pnas.0806268105. PMC 2533230. PMID 18757741.
Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD (August 2008). "Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction". Toxicology and Applied Pharmacology. 230 (3): 383–389. Bibcode:2008ToxAP.230..383W. doi:10.1016/j.taap.2008.03.003. PMC 2610481. PMID 18417180.

landesbioscience.com

Neumann CA, Cao J, Manevich Y (December 2009). "Peroxiredoxin 1 and its role in cell signaling" (PDF). Cell Cycle. 8 (24). Georgetown, Tex.: 4072–4078. doi:10.4161/cc.8.24.10242. PMC 7161701. PMID 19923889.

newscientist.com

"Natural antioxidants could scupper tumour's detox". New Scientist (2820). July 6, 2011. Retrieved 8 October 2014.

nih.gov

pubmed.ncbi.nlm.nih.gov

Moi P, Chan K, Asunis I, Cao A, Kan YW (October 1994). "Isolation of NF-E2-related factor 2 (NRF2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9926–9930. Bibcode:1994PNAS...91.9926M. doi:10.1073/pnas.91.21.9926. PMC 44930. PMID 7937919.
Gold R, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, et al. (September 2012). "Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis". The New England Journal of Medicine. 367 (12): 1098–1107. doi:10.1056/NEJMoa1114287. hdl:2078.1/124401. PMID 22992073.
Gureev AP, Popov VN, Starkov AA (2020). "Crosstalk between the mTOR and Nrf2/ARE signaling pathways as a target in the improvement of long-term potentiation". Experimental Neurology. 328: 113285. doi:10.1016/j.expneurol.2020.113285. PMC 7145749. PMID 32165256.
Zhu Y, Yang Q, Liu H, Chen W (2020). "Phytochemical compounds targeting on Nrf2 for chemoprevention in colorectal cancer". European Journal of Pharmacology. 887: 173588. doi:10.1016/j.ejphar.2020.173588. PMID 32961170. S2CID 221863319.
Ahmed S, Luo L, Tang X (2017). "Nrf2 signaling pathway: Pivotal roles in inflammation". Biochimica et Biophysica Acta. Molecular Basis of Disease. 1863 (2): 585–597. doi:10.1016/j.bbadis.2016.11.005. PMID 27825853.
He F, Ru X, Wen T (January 2020). "NRF2, a Transcription Factor for Stress Response and Beyond". International Journal of Molecular Sciences. 21 (13): 4777. doi:10.3390/ijms21134777. PMC 7369905. PMID 32640524. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD (January 2019). "Modulating NRF2 in Disease: Timing Is Everything". Annual Review of Pharmacology and Toxicology. 59: 555–575. doi:10.1146/annurev-pharmtox-010818-021856. PMC 6538038. PMID 30256716.
Chan JY, Cheung MC, Moi P, Chan K, Kan YW (March 1995). "Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization". Human Genetics. 95 (3): 265–269. doi:10.1007/BF00225191. PMID 7868116. S2CID 23774837.
Motohashi H, Yamamoto M (November 2004). "Nrf2-Keap1 defines a physiologically important stress response mechanism". Trends in Molecular Medicine. 10 (11): 549–557. doi:10.1016/j.molmed.2004.09.003. PMID 15519281.
Tonelli C, Chio II, Tuveson DA (December 2018). "Transcriptional Regulation by Nrf2". Antioxidants & Redox Signaling. 29 (17): 1727–1745. doi:10.1089/ars.2017.7342. PMC 6208165. PMID 28899199.
McMahon M, Thomas N, Itoh K, Yamamoto M, Hayes JD (July 2004). "Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron". The Journal of Biological Chemistry. 279 (30): 31556–31567. doi:10.1074/jbc.M403061200. PMID 15143058.
Motohashi H, Katsuoka F, Engel JD, Yamamoto M (April 2004). "Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway". Proceedings of the National Academy of Sciences of the United States of America. 101 (17): 6379–6384. Bibcode:2004PNAS..101.6379M. doi:10.1073/pnas.0305902101. PMC 404053. PMID 15087497.
Nioi P, Nguyen T, Sherratt PJ, Pickett CB (December 2005). "The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation". Molecular and Cellular Biology. 25 (24): 10895–10906. doi:10.1128/MCB.25.24.10895-10906.2005. PMC 1316965. PMID 16314513.
Kopacz A, Rojo AI, Patibandla C, Lastra-Martínez D, Piechota-Polanczyk A, Kloska D, et al. (November 2022). "Overlooked and valuable facts to know in the NRF2/KEAP1 field". Free Radical Biology & Medicine. 192: 37–49. doi:10.1016/j.freeradbiomed.2022.08.044. hdl:10261/289786. PMID 36100148.
Karunatilleke NC, Brickenden A, Choy WY (September 2024). "Molecular basis of the interactions between the disordered Neh4 and Neh5 domains of Nrf2 and CBP/p300 in oxidative stress response". Protein Science. 33 (9): e5137. doi:10.1002/pro.5137. PMC 11328122. PMID 39150085.
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, et al. (January 1999). "Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain". Genes & Development. 13 (1): 76–86. doi:10.1101/gad.13.1.76. PMC 316370. PMID 9887101.
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, et al. (August 2004). "Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2". Molecular and Cellular Biology. 24 (16): 7130–7139. doi:10.1128/MCB.24.16.7130-7139.2004. PMC 479737. PMID 15282312.
Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, et al. (April 2008). "Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity". Molecular and Cellular Biology. 28 (8): 2758–2770. doi:10.1128/MCB.01704-07. PMC 2293100. PMID 18268004.
Sekhar KR, Rachakonda G, Freeman ML (April 2010). "Cysteine-based regulation of the CUL3 adaptor protein Keap1". Toxicology and Applied Pharmacology. 244 (1): 21–26. Bibcode:2010ToxAP.244...21S. doi:10.1016/j.taap.2009.06.016. PMC 2837771. PMID 19560482.
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, et al. (July 1997). "An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements". Biochemical and Biophysical Research Communications. 236 (2): 313–322. doi:10.1006/bbrc.1997.6943. PMID 9240432.
Venugopal R, Jaiswal AK (December 1996). "Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene". Proceedings of the National Academy of Sciences of the United States of America. 93 (25): 14960–14965. Bibcode:1996PNAS...9314960V. doi:10.1073/pnas.93.25.14960. PMC 26245. PMID 8962164.
Solis WA, Dalton TP, Dieter MZ, Freshwater S, Harrer JM, He L, et al. (May 2002). "Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress". Biochemical Pharmacology. 63 (9): 1739–1754. doi:10.1016/S0006-2952(02)00897-3. PMID 12007577.
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