Analysis of information sources in references of the Wikipedia article "Natural product" in English language version.
Natural products are organic compounds that are formed by living systems.
Natural product: A single chemical compound that occurs naturally. This term is typically used to refer to an organic compound of limited distribution in nature (often called secondary metabolites).
Secondary metabolites are distinguished more precisely by the following criteria: they have a restricted distribution being found mostly in plants and microorganisms, and are often characteristic of individual genera, species, or strains; they are formed along specialized pathwasys from primary metabolites. Primary metabolites, by contrast, have a broad distribution in all living things and are intimately involved in essential life processes.
The simplest definition for a natural product is a small molecule that is produced by a biological source.
Figure 1. All new approved drugs 01JAN81 to 30SEP19; n = 1881. Figure 9. N/NB/ND & S* categories 01JAN81 to 30SEP19, n = 506.Natural products represent 100*(506/1881) = 27% of new drug approvals from 01JAN81 to 30SEP19. From Figure 9, the percentage was ~10% for 2017-2019.
In 1891, following Stahls work on plant biochemistry, Kossel suggested a distinction between basic and secondary metabolism (Stahl 1888).
The current, generally accepted concept in line with Kossel's view is that primary metabolites are chemical components of living organisms that are vital for their normal functioning, while secondary metabolites are compounds which are dispensable.
Adipose tissue plays a critical role in mammalian life history strategies, serving as an organ for the storage of food and energy, as a source of heat and water, and as thermal insulation.
In 1891, following Stahls work on plant biochemistry, Kossel suggested a distinction between basic and secondary metabolism (Stahl 1888).
Drug Discovery – Is Mother Nature still the number one source for promising new drugs?
Natural products: naturally occurring compounds that are end products of secondary metabolism; often, they are unique compounds for particular organisms or classes of organisms.
Natural products are represented by a wide array of consumer goods that continue to grow in popularity each year. These products include natural and organic foods, dietary supplements, pet foods, health and beauty products, "green" cleaning supplies and more. Generally, natural products are considered those formulated without artificial ingredients and that are minimally processed.
The simplest definition for a natural product is a small molecule that is produced by a biological source.
Figure 1. All new approved drugs 01JAN81 to 30SEP19; n = 1881. Figure 9. N/NB/ND & S* categories 01JAN81 to 30SEP19, n = 506.Natural products represent 100*(506/1881) = 27% of new drug approvals from 01JAN81 to 30SEP19. From Figure 9, the percentage was ~10% for 2017-2019.
Natural products include a large and diverse group of substances from a variety of sources. They are produced by marine organisms, bacteria, fungi, and plants. The term encompasses complex extracts from these producers, but also the isolated compounds derived from those extracts. It also includes vitamins, minerals and probiotics.
A chemical substance produced by a living organism; – a term used commonly in reference to chemical substances found in nature that have distinctive pharmacological effects. Such a substance is considered a natural product even if it can be prepared by total synthesis.
Natural products: naturally occurring compounds that are end products of secondary metabolism; often, they are unique compounds for particular organisms or classes of organisms.
Drug Discovery – Is Mother Nature still the number one source for promising new drugs?
