Neurotrophin (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Neurotrophin" in English language version.

refsWebsite

Global rank English rank

38nih.gov

4^th place

26doi.org

2^nd place

9semanticscholar.org

11^th place

8^th place

2harvard.edu

18^th place

17^th place

2zenodo.org

621^st place

380^th place

1web.archive.org

1^st place

1scholar.google.com

1,697^th place

1,040^th place

1csic.es

2,323^rd place

3,364^th place

1handle.net

102^nd place

76^th place

csic.es

digital.csic.es

Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.

doi.org

Hempstead BL (February 2006). "Dissecting the diverse actions of pro- and mature neurotrophins". Current Alzheimer Research. 3 (1): 19–24. doi:10.2174/156720506775697061. PMID 16472198. Archived from the original on 2009-08-30. Retrieved 2020-04-16.{{cite journal}}: CS1 maint: unfit URL (link)
Reichardt LF (September 2006). "Neurotrophin-regulated signalling pathways". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361 (1473): 1545–1564. doi:10.1098/rstb.2006.1894. PMC 1664664. PMID 16939974.
Allen SJ, Dawbarn D (February 2006). "Clinical relevance of the neurotrophins and their receptors". Clinical Science. 110 (2): 175–191. doi:10.1042/CS20050161. PMID 16411894. S2CID 9507693.
Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH (November 1998). "Neurogenesis in the adult human hippocampus". Nature Medicine. 4 (11): 1313–1317. doi:10.1038/3305. PMID 9809557.
Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA (August 1990). "Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain". The EMBO Journal. 9 (8): 2459–2464. doi:10.1002/j.1460-2075.1990.tb07423.x. PMC 552273. PMID 2369898.
Wistow G, Piatigorsky J (June 1987). "Recruitment of enzymes as lens structural proteins". Science. 236 (4808): 1554–1556. Bibcode:1987Sci...236.1554W. doi:10.1126/science.3589669. PMID 3589669.
Bradshaw RA, Blundell TL, Lapatto R, McDonald NQ, Murray-Rust J (February 1993). "Nerve growth factor revisited". Trends in Biochemical Sciences. 18 (2): 48–52. doi:10.1016/0968-0004(93)90052-O. PMID 8488558.
Koyama J, Inoue S, Ikeda K, Hayashi K (December 1992). "Purification and amino-acid sequence of a nerve growth factor from the venom of Vipera russelli russelli". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1160 (3): 287–292. doi:10.1016/0167-4838(92)90090-Z. PMID 1477101.
Inoue S, Oda T, Koyama J, Ikeda K, Hayashi K (February 1991). "Amino acid sequences of nerve growth factors derived from cobra venoms". FEBS Letters. 279 (1): 38–40. doi:10.1016/0014-5793(91)80244-W. PMID 1995338.
Arévalo JC, Wu SH (July 2006). "Neurotrophin signaling: many exciting surprises!". Cellular and Molecular Life Sciences. 63 (13): 1523–1537. doi:10.1007/s00018-006-6010-1. PMC 11135985. PMID 16699811. S2CID 23869093.
Harrington AW, Ginty DD (March 2013). "Long-distance retrograde neurotrophic factor signalling in neurons". Nature Reviews. Neuroscience. 14 (3): 177–187. doi:10.1038/nrn3253. PMID 23422909. S2CID 29211700.
Prough RA, Clark BJ, Klinge CM (April 2016). "Novel mechanisms for DHEA action". Journal of Molecular Endocrinology. 56 (3): R139–155. doi:10.1530/JME-16-0013. PMID 26908835.
Lazaridis I, Charalampopoulos I, Alexaki VI, Avlonitis N, Pediaditakis I, Efstathopoulos P, Calogeropoulou T, Castanas E, Gravanis A (April 2011). "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS Biology. 9 (4): e1001051. doi:10.1371/journal.pbio.1001051. PMC 3082517. PMID 21541365.
Pediaditakis I, Iliopoulos I, Theologidis I, Delivanoglou N, Margioris AN, Charalampopoulos I, Gravanis A (January 2015). "Dehydroepiandrosterone: an ancestral ligand of neurotrophin receptors". Endocrinology. 156 (1): 16–23. doi:10.1210/en.2014-1596. PMID 25330101.
Gravanis A, Calogeropoulou T, Panoutsakopoulou V, Thermos K, Neophytou C, Charalampopoulos I (October 2012). "Neurosteroids and microneurotrophins signal through NGF receptors to induce prosurvival signaling in neuronal cells". Science Signaling. 5 (246): pt8. doi:10.1126/scisignal.2003387. PMID 23074265. S2CID 26914550.
Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD (February 1998). "The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death". The Journal of Cell Biology. 140 (4): 911–923. doi:10.1083/jcb.140.4.911. PMC 2141754. PMID 9472042.
Lu B, Pang PT, Woo NH (August 2005). "The yin and yang of neurotrophin action". Nature Reviews. Neuroscience. 6 (8): 603–614. doi:10.1038/nrn1726. PMID 16062169. S2CID 15915753.
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.
Teng KK, Felice S, Kim T, Hempstead BL (April 2010). "Understanding proneurotrophin actions: Recent advances and challenges". Developmental Neurobiology. 70 (5): 350–359. doi:10.1002/dneu.20768. PMC 3063094. PMID 20186707.
Dhanasekaran DN, Reddy EP (October 2008). "JNK signaling in apoptosis". Oncogene. 27 (48): 6245–6251. doi:10.1038/onc.2008.301. PMC 3063296. PMID 18931691.
Huang EJ, Reichardt LF (2001). "Neurotrophins: roles in neuronal development and function". Annual Review of Neuroscience. 24: 677–736. doi:10.1146/annurev.neuro.24.1.677. PMC 2758233. PMID 11520916.
Longo FM, Massa SM (July 2013). "Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease". Nature Reviews. Drug Discovery. 12 (7): 507–525. doi:10.1038/nrd4024. PMID 23977697. S2CID 33597483.
Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV (May 1998). "Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival". The Journal of Neuroscience. 18 (9): 3273–3281. doi:10.1523/JNEUROSCI.18-09-03273.1998. PMC 6792655. PMID 9547236.
Dekkers MP, Nikoletopoulou V, Barde YA (November 2013). "Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity". The Journal of Cell Biology. 203 (3): 385–393. doi:10.1083/jcb.201306136. PMC 3824005. PMID 24217616.
Lessmann V, Gottmann K, Malcangio M (April 2003). "Neurotrophin secretion: current facts and future prospects". Progress in Neurobiology. 69 (5): 341–374. doi:10.1016/s0301-0082(03)00019-4. PMID 12787574. S2CID 16624509.
Ernsberger U (June 2009). "Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia". Cell and Tissue Research. 336 (3): 349–384. doi:10.1007/S00441-009-0784-Z. PMID 19387688. S2CID 20325630.

handle.net

hdl.handle.net

Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.

harvard.edu

ui.adsabs.harvard.edu

Wistow G, Piatigorsky J (June 1987). "Recruitment of enzymes as lens structural proteins". Science. 236 (4808): 1554–1556. Bibcode:1987Sci...236.1554W. doi:10.1126/science.3589669. PMID 3589669.
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.

nih.gov

pubmed.ncbi.nlm.nih.gov

Hempstead BL (February 2006). "Dissecting the diverse actions of pro- and mature neurotrophins". Current Alzheimer Research. 3 (1): 19–24. doi:10.2174/156720506775697061. PMID 16472198. Archived from the original on 2009-08-30. Retrieved 2020-04-16.{{cite journal}}: CS1 maint: unfit URL (link)
Reichardt LF (September 2006). "Neurotrophin-regulated signalling pathways". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361 (1473): 1545–1564. doi:10.1098/rstb.2006.1894. PMC 1664664. PMID 16939974.
Allen SJ, Dawbarn D (February 2006). "Clinical relevance of the neurotrophins and their receptors". Clinical Science. 110 (2): 175–191. doi:10.1042/CS20050161. PMID 16411894. S2CID 9507693.
Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH (November 1998). "Neurogenesis in the adult human hippocampus". Nature Medicine. 4 (11): 1313–1317. doi:10.1038/3305. PMID 9809557.
Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA (August 1990). "Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain". The EMBO Journal. 9 (8): 2459–2464. doi:10.1002/j.1460-2075.1990.tb07423.x. PMC 552273. PMID 2369898.
Wistow G, Piatigorsky J (June 1987). "Recruitment of enzymes as lens structural proteins". Science. 236 (4808): 1554–1556. Bibcode:1987Sci...236.1554W. doi:10.1126/science.3589669. PMID 3589669.
Bradshaw RA, Blundell TL, Lapatto R, McDonald NQ, Murray-Rust J (February 1993). "Nerve growth factor revisited". Trends in Biochemical Sciences. 18 (2): 48–52. doi:10.1016/0968-0004(93)90052-O. PMID 8488558.
Koyama J, Inoue S, Ikeda K, Hayashi K (December 1992). "Purification and amino-acid sequence of a nerve growth factor from the venom of Vipera russelli russelli". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1160 (3): 287–292. doi:10.1016/0167-4838(92)90090-Z. PMID 1477101.
Inoue S, Oda T, Koyama J, Ikeda K, Hayashi K (February 1991). "Amino acid sequences of nerve growth factors derived from cobra venoms". FEBS Letters. 279 (1): 38–40. doi:10.1016/0014-5793(91)80244-W. PMID 1995338.
Arévalo JC, Wu SH (July 2006). "Neurotrophin signaling: many exciting surprises!". Cellular and Molecular Life Sciences. 63 (13): 1523–1537. doi:10.1007/s00018-006-6010-1. PMC 11135985. PMID 16699811. S2CID 23869093.
Harrington AW, Ginty DD (March 2013). "Long-distance retrograde neurotrophic factor signalling in neurons". Nature Reviews. Neuroscience. 14 (3): 177–187. doi:10.1038/nrn3253. PMID 23422909. S2CID 29211700.
Prough RA, Clark BJ, Klinge CM (April 2016). "Novel mechanisms for DHEA action". Journal of Molecular Endocrinology. 56 (3): R139–155. doi:10.1530/JME-16-0013. PMID 26908835.
Lazaridis I, Charalampopoulos I, Alexaki VI, Avlonitis N, Pediaditakis I, Efstathopoulos P, Calogeropoulou T, Castanas E, Gravanis A (April 2011). "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS Biology. 9 (4): e1001051. doi:10.1371/journal.pbio.1001051. PMC 3082517. PMID 21541365.
Pediaditakis I, Iliopoulos I, Theologidis I, Delivanoglou N, Margioris AN, Charalampopoulos I, Gravanis A (January 2015). "Dehydroepiandrosterone: an ancestral ligand of neurotrophin receptors". Endocrinology. 156 (1): 16–23. doi:10.1210/en.2014-1596. PMID 25330101.
Gravanis A, Calogeropoulou T, Panoutsakopoulou V, Thermos K, Neophytou C, Charalampopoulos I (October 2012). "Neurosteroids and microneurotrophins signal through NGF receptors to induce prosurvival signaling in neuronal cells". Science Signaling. 5 (246): pt8. doi:10.1126/scisignal.2003387. PMID 23074265. S2CID 26914550.
Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD (February 1998). "The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death". The Journal of Cell Biology. 140 (4): 911–923. doi:10.1083/jcb.140.4.911. PMC 2141754. PMID 9472042.
Lu B, Pang PT, Woo NH (August 2005). "The yin and yang of neurotrophin action". Nature Reviews. Neuroscience. 6 (8): 603–614. doi:10.1038/nrn1726. PMID 16062169. S2CID 15915753.
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.
Teng KK, Felice S, Kim T, Hempstead BL (April 2010). "Understanding proneurotrophin actions: Recent advances and challenges". Developmental Neurobiology. 70 (5): 350–359. doi:10.1002/dneu.20768. PMC 3063094. PMID 20186707.
Dhanasekaran DN, Reddy EP (October 2008). "JNK signaling in apoptosis". Oncogene. 27 (48): 6245–6251. doi:10.1038/onc.2008.301. PMC 3063296. PMID 18931691.
Huang EJ, Reichardt LF (2001). "Neurotrophins: roles in neuronal development and function". Annual Review of Neuroscience. 24: 677–736. doi:10.1146/annurev.neuro.24.1.677. PMC 2758233. PMID 11520916.
Longo FM, Massa SM (July 2013). "Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease". Nature Reviews. Drug Discovery. 12 (7): 507–525. doi:10.1038/nrd4024. PMID 23977697. S2CID 33597483.
Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV (May 1998). "Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival". The Journal of Neuroscience. 18 (9): 3273–3281. doi:10.1523/JNEUROSCI.18-09-03273.1998. PMC 6792655. PMID 9547236.
Dekkers MP, Nikoletopoulou V, Barde YA (November 2013). "Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity". The Journal of Cell Biology. 203 (3): 385–393. doi:10.1083/jcb.201306136. PMC 3824005. PMID 24217616.
Lessmann V, Gottmann K, Malcangio M (April 2003). "Neurotrophin secretion: current facts and future prospects". Progress in Neurobiology. 69 (5): 341–374. doi:10.1016/s0301-0082(03)00019-4. PMID 12787574. S2CID 16624509.
Ernsberger U (June 2009). "Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia". Cell and Tissue Research. 336 (3): 349–384. doi:10.1007/S00441-009-0784-Z. PMID 19387688. S2CID 20325630.

ncbi.nlm.nih.gov

Reichardt LF (September 2006). "Neurotrophin-regulated signalling pathways". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361 (1473): 1545–1564. doi:10.1098/rstb.2006.1894. PMC 1664664. PMID 16939974.
Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA (August 1990). "Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain". The EMBO Journal. 9 (8): 2459–2464. doi:10.1002/j.1460-2075.1990.tb07423.x. PMC 552273. PMID 2369898.
Arévalo JC, Wu SH (July 2006). "Neurotrophin signaling: many exciting surprises!". Cellular and Molecular Life Sciences. 63 (13): 1523–1537. doi:10.1007/s00018-006-6010-1. PMC 11135985. PMID 16699811. S2CID 23869093.
"Entrez database entry for NT-4/5". NCBI. Retrieved 2007-05-07.
Lazaridis I, Charalampopoulos I, Alexaki VI, Avlonitis N, Pediaditakis I, Efstathopoulos P, Calogeropoulou T, Castanas E, Gravanis A (April 2011). "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS Biology. 9 (4): e1001051. doi:10.1371/journal.pbio.1001051. PMC 3082517. PMID 21541365.
Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD (February 1998). "The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death". The Journal of Cell Biology. 140 (4): 911–923. doi:10.1083/jcb.140.4.911. PMC 2141754. PMID 9472042.
Teng KK, Felice S, Kim T, Hempstead BL (April 2010). "Understanding proneurotrophin actions: Recent advances and challenges". Developmental Neurobiology. 70 (5): 350–359. doi:10.1002/dneu.20768. PMC 3063094. PMID 20186707.
Dhanasekaran DN, Reddy EP (October 2008). "JNK signaling in apoptosis". Oncogene. 27 (48): 6245–6251. doi:10.1038/onc.2008.301. PMC 3063296. PMID 18931691.
Huang EJ, Reichardt LF (2001). "Neurotrophins: roles in neuronal development and function". Annual Review of Neuroscience. 24: 677–736. doi:10.1146/annurev.neuro.24.1.677. PMC 2758233. PMID 11520916.
Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV (May 1998). "Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival". The Journal of Neuroscience. 18 (9): 3273–3281. doi:10.1523/JNEUROSCI.18-09-03273.1998. PMC 6792655. PMID 9547236.
Dekkers MP, Nikoletopoulou V, Barde YA (November 2013). "Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity". The Journal of Cell Biology. 203 (3): 385–393. doi:10.1083/jcb.201306136. PMC 3824005. PMID 24217616.

meshb.nlm.nih.gov

Neurotrophins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

scholar.google.com

"Exercise builds brain health: key roles of growth factor cascades and inflammation" by Carl W. Cotman, Nicole C. Berchtold and Lori-Ann Christie https://scholar.google.com/scholar?cluster=11830727319998892361&hl=en&as_sdt=0,10

semanticscholar.org

api.semanticscholar.org

Allen SJ, Dawbarn D (February 2006). "Clinical relevance of the neurotrophins and their receptors". Clinical Science. 110 (2): 175–191. doi:10.1042/CS20050161. PMID 16411894. S2CID 9507693.
Arévalo JC, Wu SH (July 2006). "Neurotrophin signaling: many exciting surprises!". Cellular and Molecular Life Sciences. 63 (13): 1523–1537. doi:10.1007/s00018-006-6010-1. PMC 11135985. PMID 16699811. S2CID 23869093.
Harrington AW, Ginty DD (March 2013). "Long-distance retrograde neurotrophic factor signalling in neurons". Nature Reviews. Neuroscience. 14 (3): 177–187. doi:10.1038/nrn3253. PMID 23422909. S2CID 29211700.
Gravanis A, Calogeropoulou T, Panoutsakopoulou V, Thermos K, Neophytou C, Charalampopoulos I (October 2012). "Neurosteroids and microneurotrophins signal through NGF receptors to induce prosurvival signaling in neuronal cells". Science Signaling. 5 (246): pt8. doi:10.1126/scisignal.2003387. PMID 23074265. S2CID 26914550.
Lu B, Pang PT, Woo NH (August 2005). "The yin and yang of neurotrophin action". Nature Reviews. Neuroscience. 6 (8): 603–614. doi:10.1038/nrn1726. PMID 16062169. S2CID 15915753.
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA (September 2010). "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not" (PDF). Nature. 467 (7311): 59–63. Bibcode:2010Natur.467...59N. doi:10.1038/nature09336. hdl:10261/27437. PMID 20811452. S2CID 205222117.
Longo FM, Massa SM (July 2013). "Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease". Nature Reviews. Drug Discovery. 12 (7): 507–525. doi:10.1038/nrd4024. PMID 23977697. S2CID 33597483.
Lessmann V, Gottmann K, Malcangio M (April 2003). "Neurotrophin secretion: current facts and future prospects". Progress in Neurobiology. 69 (5): 341–374. doi:10.1016/s0301-0082(03)00019-4. PMID 12787574. S2CID 16624509.
Ernsberger U (June 2009). "Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia". Cell and Tissue Research. 336 (3): 349–384. doi:10.1007/S00441-009-0784-Z. PMID 19387688. S2CID 20325630.

web.archive.org

Hempstead BL (February 2006). "Dissecting the diverse actions of pro- and mature neurotrophins". Current Alzheimer Research. 3 (1): 19–24. doi:10.2174/156720506775697061. PMID 16472198. Archived from the original on 2009-08-30. Retrieved 2020-04-16.{{cite journal}}: CS1 maint: unfit URL (link)

zenodo.org

Pediaditakis I, Iliopoulos I, Theologidis I, Delivanoglou N, Margioris AN, Charalampopoulos I, Gravanis A (January 2015). "Dehydroepiandrosterone: an ancestral ligand of neurotrophin receptors". Endocrinology. 156 (1): 16–23. doi:10.1210/en.2014-1596. PMID 25330101.
Lu B, Pang PT, Woo NH (August 2005). "The yin and yang of neurotrophin action". Nature Reviews. Neuroscience. 6 (8): 603–614. doi:10.1038/nrn1726. PMID 16062169. S2CID 15915753.