Olanzapine (English Wikipedia)

Kassahun K, Mattiuz E, Nyhart E, Obermeyer B, Gillespie T, Murphy A, et al. (January 1997). "Disposition and biotransformation of the antipsychotic agent olanzapine in humans". Drug Metabolism and Disposition. 25 (1): 81–93. PMID 9010634.

astrazenecaclinicaltrials.com

AstraZeneca Pharmaceuticals (4 April 2006). "Efficacy and Tolerability of Olanzapine, Quetiapine and Risperidone in the Treatment of First Episode Psychosis: A Randomised Double Blind 52 Week Comparison". AstraZeneca Clinical Trials. AstraZeneca PLC. Archived from the original on 13 November 2007. Retrieved 3 December 2007. At week 12, the olanzapine-treated group had more weight gain, a higher increase in [ body mass index ], and a higher proportion of patients with a BMI increase of at least 1 unit compared with the quetiapine and risperidone groups (p<=0.01).

bbc.co.uk

news.bbc.co.uk

"Doctors 'ignoring drugs warning'". BBC News. 17 June 2008. Retrieved 22 June 2008.

books.google.com

Taylor D, Paton C, Kapur S (2015). The Maudsley Prescribing Guidelines in Psychiatry (12th ed.). London, U K: Wiley-Blackwell. p. 16. ISBN 978-1-118-75460-3.
Haddad P, Haddad PM, Dursun S, Deakin B (2004). Adverse Syndromes and Psychiatric Drugs: A Clinical Guide. OUP Oxford. pp. 207–216. ISBN 978-0-19-852748-0.
Sacchetti E, Vita A, Siracusano A, Fleischhacker W (2013). Adherence to Antipsychotics in Schizophrenia. Springer Science & Business Media. p. 85. ISBN 978-88-470-2679-7.

cancer.gov

"olanzapine". NCI Drug Dictionary. National Cancer Institute. 2 February 2011.

clincalc.com

"The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
"Olanzapine Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.

doi.org

Callaghan JT, Bergstrom RF, Ptak LR, Beasley CM (September 1999). "Olanzapine. Pharmacokinetic and pharmacodynamic profile". Clinical Pharmacokinetics. 37 (3): 177–193. doi:10.2165/00003088-199937030-00001. PMID 10511917.
Mauri MC, Volonteri LS, Colasanti A, Fiorentini A, De Gaspari IF, Bareggi SR (2007). "Clinical pharmacokinetics of atypical antipsychotics: a critical review of the relationship between plasma concentrations and clinical response". Clinical Pharmacokinetics. 46 (5): 359–388. doi:10.2165/00003088-200746050-00001. PMID 17465637. S2CID 43859718.
Razvi Y, Chan S, McFarlane T, McKenzie E, Zaki P, DeAngelis C, et al. (January 2019). "ASCO, NCCN, MASCC/ESMO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in adult patients". Supportive Care in Cancer. 27 (1): 87–95. doi:10.1007/s00520-018-4464-y. PMID 30284039.
Sandhya L, Devi Sreenivasan N, Goenka L, Dubashi B, Kayal S, Solaiappan M, et al. (May 2023). "Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer". Journal of Clinical Oncology. 41 (14): 2617–2627. doi:10.1200/JCO.22.01997. PMID 36977285.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, et al. (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019. S2CID 32085212.
Harvey RC, James AC, Shields GE (January 2016). "A Systematic Review and Network Meta-Analysis to Assess the Relative Efficacy of Antipsychotics for the Treatment of Positive and Negative Symptoms in Early-Onset Schizophrenia". CNS Drugs. 30 (1): 27–39. doi:10.1007/s40263-015-0308-1. PMID 26801655. S2CID 35702889.
Pagsberg AK, Tarp S, Glintborg D, Stenstrøm AD, Fink-Jensen A, Correll CU, et al. (March 2017). "Acute Antipsychotic Treatment of Children and Adolescents With Schizophrenia-Spectrum Disorders: A Systematic Review and Network Meta-Analysis". Journal of the American Academy of Child and Adolescent Psychiatry. 56 (3): 191–202. doi:10.1016/j.jaac.2016.12.013. PMID 28219485.
Osser DN, Roudsari MJ, Manschreck T (2013). "The psychopharmacology algorithm project at the Harvard South Shore Program: an update on schizophrenia". Harvard Review of Psychiatry. 21 (1): 18–40. doi:10.1097/HRP.0b013e31827fd915. PMID 23656760. S2CID 22523977.
Duggan L, Fenton M, Rathbone J, Dardennes R, El-Dosoky A, Indran S (April 2005). "Olanzapine for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (2): CD001359. doi:10.1002/14651858.CD001359.pub2. PMC 11781594. PMID 15846619.
Komossa K, Rummel-Kluge C, Hunger H, Schmid F, Schwarz S, Duggan L, et al. (March 2010). "Olanzapine versus other atypical antipsychotics for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (3): CD006654. doi:10.1002/14651858.CD006654.pub2. PMC 4169107. PMID 20238348.
McKeage K (February 2014). "Aripiprazole: a review of its use in the treatment of manic episodes in adolescents with bipolar I disorder". CNS Drugs. 28 (2): 171–183. doi:10.1007/s40263-013-0134-2. PMID 24399490. S2CID 199974.
Yatham LN, Kennedy SH, O'Donovan C, Parikh SV, MacQueen G, McIntyre RS, et al. (December 2006). "Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 2007". Bipolar Disorders. 8 (6): 721–739. doi:10.1111/j.1399-5618.2006.00432.x. PMID 17156158.
Dando S, Tohen M (March 2006). "Olanzapine - relapse prevention following mania". Journal of Psychopharmacology. 20 (2 Suppl): 31–38. doi:10.1177/1359786806063076. PMID 16551670. S2CID 34435730.
Selle V, Schalkwijk S, Vázquez GH, Baldessarini RJ (March 2014). "Treatments for acute bipolar depression: meta-analyses of placebo-controlled, monotherapy trials of anticonvulsants, lithium and antipsychotics". Pharmacopsychiatry. 47 (2): 43–52. doi:10.1055/s-0033-1363258. PMID 24549862.
Rasmussen SA, Chu SY, Kim SY, Schmid CH, Lau J (June 2008). "Maternal obesity and risk of neural tube defects: a metaanalysis". American Journal of Obstetrics and Gynecology. 198 (6): 611–619. doi:10.1016/j.ajog.2008.04.021. PMID 18538144.
McMahon DM, Liu J, Zhang H, Torres ME, Best RG (February 2013). "Maternal obesity, folate intake, and neural tube defects in offspring". Birth Defects Research. Part A, Clinical and Molecular Teratology. 97 (2): 115–122. doi:10.1002/bdra.23113. PMID 23404872.
Yeung EY, Chun S, Douglass A, Lau TE (8 May 2017). "Effect of atypical antipsychotics on body weight in geriatric psychiatric inpatients". SAGE Open Medicine. 5: 2050312117708711. doi:10.1177/2050312117708711. PMC 5431608. PMID 28540050.
Gupta S, Lakshmanan DA, Khastgir U, Nair R (2017). "Management of antipsychotic-induced hyperprolactinaemia". BJPsych Advances. 23 (4): 278–286. doi:10.1192/apt.bp.115.014928. ISSN 2056-4678. S2CID 80025501.
Stöllberger C, Lutz W, Finsterer J (July 2009). "Heat-related side-effects of neurological and non-neurological medication may increase heatwave fatalities". European Journal of Neurology. 16 (7): 879–882. doi:10.1111/j.1468-1331.2009.02581.x. PMID 19453697. S2CID 25016607.
Ramankutty G (March 2002). "Olanzapine-induced destabilization of diabetes in the absence of weight gain". Acta Psychiatrica Scandinavica. 105 (3): 235–6, discussion 236–7. doi:10.1034/j.1600-0447.2002.2c257a.x. PMID 11939979. S2CID 5965031.
Lambert MT, Copeland LA, Sampson N, Duffy SA (July 2006). "New-onset type-2 diabetes associated with atypical antipsychotic medications". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30 (5): 919–923. doi:10.1016/j.pnpbp.2006.02.007. PMID 16581171. S2CID 24739534.
Wirshing DA, Wirshing WC, Kysar L, Berisford MA, Goldstein D, Pashdag J, et al. (June 1999). "Novel antipsychotics: comparison of weight gain liabilities". The Journal of Clinical Psychiatry. 60 (6): 358–363. doi:10.4088/JCP.v60n0602. PMID 10401912.
McEvoy JP, Lieberman JA, Perkins DO, Hamer RM, Gu H, Lazarus A, et al. (July 2007). "Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison". The American Journal of Psychiatry. 164 (7): 1050–1060. doi:10.1176/ajp.2007.164.7.1050. PMID 17606657.
Fulbright AR, Breedlove KT (2006). "Complete Resolution of Olanzapine-Induced Diabetic Ketoacidosis". Journal of Pharmacy Practice. 19 (4): 255–8. doi:10.1177/0897190006294180. S2CID 73047103.
Chiu CC, Chen CH, Chen BY, Yu SH, Lu ML (August 2010). "The time-dependent change of insulin secretion in schizophrenic patients treated with olanzapine". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34 (6): 866–870. doi:10.1016/j.pnpbp.2010.04.003. PMID 20394794. S2CID 22445875.
Sacher J, Mossaheb N, Spindelegger C, Klein N, Geiss-Granadia T, Sauermann R, et al. (June 2008). "Effects of olanzapine and ziprasidone on glucose tolerance in healthy volunteers". Neuropsychopharmacology. 33 (7): 1633–1641. doi:10.1038/sj.npp.1301541. PMID 17712347.
Sowell M, Mukhopadhyay N, Cavazzoni P, Carlson C, Mudaliar S, Chinnapongse S, et al. (December 2003). "Evaluation of insulin sensitivity in healthy volunteers treated with olanzapine, risperidone, or placebo: a prospective, randomized study using the two-step hyperinsulinemic, euglycemic clamp". The Journal of Clinical Endocrinology and Metabolism. 88 (12): 5875–5880. doi:10.1210/jc.2002-021884. PMID 14671184.
de Haan L, van Amelsvoort T, Rosien K, Linszen D (September 2004). "Weight loss after switching from conventional olanzapine tablets to orally disintegrating olanzapine tablets". Psychopharmacology. 175 (3): 389–390. doi:10.1007/s00213-004-1951-2. PMID 15322727. S2CID 38751442.
Luedecke D, Schöttle D, Karow A, Lambert M, Naber D (January 2015). "Post-injection delirium/sedation syndrome in patients treated with olanzapine pamoate: mechanism, incidence, and management". CNS Drugs. 29 (1): 41–46. doi:10.1007/s40263-014-0216-9. PMID 25424243. S2CID 10928442.
Brambilla G, Mattioli F, Martelli A (July 2009). "Genotoxic and carcinogenic effects of antipsychotics and antidepressants". Toxicology. 261 (3): 77–88. Bibcode:2009Toxgy.261...77B. doi:10.1016/j.tox.2009.04.056. PMID 19410629.
Moncrieff J (July 2006). "Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse". Acta Psychiatrica Scandinavica. 114 (1): 3–13. doi:10.1111/j.1600-0447.2006.00787.x. PMID 16774655. S2CID 6267180.
Schwenger E, Dumontet J, Ensom MH (July 2011). "Does olanzapine warrant clinical pharmacokinetic monitoring in schizophrenia?". Clinical Pharmacokinetics. 50 (7): 415–428. doi:10.2165/11587240-000000000-00000. PMID 21651311. S2CID 21097041.
Yates G, Melon E (January 2024). "Trip-killers: a concerning practice associated with psychedelic drug use". Emerg Med J. 41 (2): 112–113. doi:10.1136/emermed-2023-213377. PMID 38123961.
Suran M (February 2024). "Study Finds Hundreds of Reddit Posts on "Trip-Killers" for Psychedelic Drugs". JAMA. 331 (8): 632–634. doi:10.1001/jama.2023.28257. PMID 38294772.
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, et al. (August 2008). "Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one". Bioorganic & Medicinal Chemistry. 16 (15): 7291–7301. doi:10.1016/j.bmc.2008.06.030. PMC 2664318. PMID 18595716.
Kroeze WK, Hufeisen SJ, Popadak BA, Renock SM, Steinberg S, Ernsberger P, et al. (March 2003). "H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs". Neuropsychopharmacology. 28 (3): 519–526. doi:10.1038/sj.npp.1300027. PMID 12629531.
Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, et al. (March 1996). "Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding". Psychopharmacology. 124 (1–2): 57–73. doi:10.1007/bf02245606. PMID 8935801. S2CID 12028979.
Davies MA, Setola V, Strachan RT, Sheffler DJ, Salay E, Hufeisen SJ, et al. (2006). "Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies". The Pharmacogenomics Journal. 6 (1): 42–51. doi:10.1038/sj.tpj.6500342. PMID 16314884.
Kongsamut S, Roehr JE, Cai J, Hartman HB, Weissensee P, Kerman LL, et al. (December 1996). "Iloperidone binding to human and rat dopamine and 5-HT receptors". European Journal of Pharmacology. 317 (2–3): 417–423. doi:10.1016/s0014-2999(96)00840-0. PMID 8997630.
Wainscott DB, Lucaites VL, Kursar JD, Baez M, Nelson DL (February 1996). "Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences". The Journal of Pharmacology and Experimental Therapeutics. 276 (2): 720–727. doi:10.1016/S0022-3565(25)12346-X. PMID 8632342.
Bymaster FP, Nelson DL, DeLapp NW, Falcone JF, Eckols K, Truex LL, et al. (May 1999). "Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro". Schizophrenia Research. 37 (1): 107–122. doi:10.1016/s0920-9964(98)00146-7. PMID 10227113. S2CID 19891653.
Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL (October 2003). "Muscarinic mechanisms of antipsychotic atypicality". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27 (7): 1125–1143. doi:10.1016/j.pnpbp.2003.09.008. PMID 14642972. S2CID 28536368.
Fernández J, Alonso JM, Andrés JI, Cid JM, Díaz A, Iturrino L, et al. (March 2005). "Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents". Journal of Medicinal Chemistry. 48 (6): 1709–1712. doi:10.1021/jm049632c. PMID 15771415.
Seeman P, Tallerico T (March 1998). "Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors". Molecular Psychiatry. 3 (2): 123–134. doi:10.1038/sj.mp.4000336. PMID 9577836.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, et al. (December 2005). "Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist". The Journal of Pharmacology and Experimental Therapeutics. 315 (3): 1278–1287. doi:10.1124/jpet.105.092155. PMID 16135699. S2CID 2247093.
Seeman P, Van Tol HH (October 1995). "Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand". European Journal of Pharmacology. 291 (2): 59–66. doi:10.1016/0922-4106(95)90125-6. PMID 8566176.
Arnt J, Skarsfeldt T (February 1998). "Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence". Neuropsychopharmacology. 18 (2): 63–101. doi:10.1016/S0893-133X(97)00112-7. PMID 9430133.
Tallman JF, Primus RJ, Brodbeck R, Cornfield L, Meade R, Woodruff K, et al. (August 1997). "I. NGD 94-1: identification of a novel, high-affinity antagonist at the human dopamine D4 receptor". The Journal of Pharmacology and Experimental Therapeutics. 282 (2): 1011–1019. doi:10.1016/S0022-3565(24)36884-3. PMID 9262370.
Bymaster FP, Calligaro DO, Falcone JF, Marsh RD, Moore NA, Tye NC, et al. (February 1996). "Radioreceptor binding profile of the atypical antipsychotic olanzapine". Neuropsychopharmacology. 14 (2): 87–96. doi:10.1016/0893-133X(94)00129-N. PMID 8822531.
Bymaster FP, Falcone JF (March 2000). "Decreased binding affinity of olanzapine and clozapine for human muscarinic receptors in intact clonal cells in physiological medium". European Journal of Pharmacology. 390 (3): 245–248. doi:10.1016/s0014-2999(00)00037-6. PMID 10708730.
Kongsamut S, Kang J, Chen XL, Roehr J, Rampe D (August 2002). "A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs". European Journal of Pharmacology. 450 (1): 37–41. doi:10.1016/s0014-2999(02)02074-5. PMID 12176106.
Citrome L, McEvoy JP, Todtenkopf MS, McDonnell D, Weiden PJ (September 2019). "A commentary on the efficacy of olanzapine for the treatment of schizophrenia: the past, present, and future". Neuropsychiatric Disease and Treatment. 15: 2559–2569. doi:10.2147/NDT.S209284. PMC 6733343. PMID 31564881.
Kapur S, Zipursky RB, Remington G, Jones C, DaSilva J, Wilson AA, et al. (July 1998). "5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation". The American Journal of Psychiatry. 155 (7): 921–928. doi:10.1176/ajp.155.7.921. PMID 9659858. S2CID 23678989.
Kessler RM, Ansari MS, Riccardi P, Li R, Jayathilake K, Dawant B, et al. (December 2005). "Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol". Neuropsychopharmacology. 30 (12): 2283–2289. doi:10.1038/sj.npp.1300836. PMID 16123775. S2CID 19688114.
Wang JS, Zhu HJ, Markowitz JS, Donovan JL, DeVane CL (September 2006). "Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein". Psychopharmacology. 187 (4): 415–423. doi:10.1007/s00213-006-0437-9. PMID 16810505. S2CID 13365903.
Moons T, de Roo M, Claes S, Dom G (August 2011). "Relationship between P-glycoprotein and second-generation antipsychotics". Pharmacogenomics. 12 (8): 1193–1211. doi:10.2217/pgs.11.55. PMID 21843066.
Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, et al. (May 2005). "Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia". Diabetes. 54 (5): 1552–1558. doi:10.2337/diabetes.54.5.1552. PMID 15855345.
Weston-Green K, Huang XF, Deng C (December 2013). "Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor". CNS Drugs. 27 (12): 1069–1080. doi:10.1007/s40263-013-0115-5. PMID 24114586. S2CID 5133679.
Silvestre JS, Prous J (June 2005). "Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes". Methods and Findings in Experimental and Clinical Pharmacology. 27 (5): 289–304. doi:10.1358/mf.2005.27.5.908643. PMID 16082416.
Van Oekelen D, Luyten WH, Leysen JE (April 2003). "5-HT2A and 5-HT2C receptors and their atypical regulation properties". Life Sciences. 72 (22): 2429–2449. doi:10.1016/s0024-3205(03)00141-3. PMID 12650852.
Reynolds GP, Hill MJ, Kirk SL (July 2006). "The 5-HT2C receptor and antipsychotic-induced weight gain - mechanisms and genetics". Journal of Psychopharmacology. 20 (4 Suppl): 15–18. doi:10.1177/1359786806066040. PMID 16785265. S2CID 19934754.
Wallace TJ, Zai CC, Brandl EJ, Müller DJ (18 August 2011). "Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain". Pharmacogenomics and Personalized Medicine. 4: 83–93. doi:10.2147/PGPM.S11866. PMC 3513221. PMID 23226055.
Reutzel-Edens SM, Bhardwaj RM (November 2020). "Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving". IUCrJ. 7 (Pt 6): 955–964. Bibcode:2020IUCrJ...7..955R. doi:10.1107/S2052252520012683. PMC 7642794. PMID 33209310.
Pillarella J, Higashi A, Alexander GC, Conti R (January 2012). "Trends in use of second-generation antipsychotics for treatment of bipolar disorder in the United States, 1998-2009". Psychiatric Services. 63 (1): 83–86. doi:10.1176/appi.ps.201100092. PMC 4594841. PMID 22227765.
Bobo WV, Shelton RC (2009). "Olanzapine and fluoxetine combination therapy for treatment-resistant depression: review of efficacy, safety, and study design issues". Neuropsychiatric Disease and Treatment. 5: 369–383. doi:10.2147/NDT.S5819. PMC 2706569. PMID 19590732.
Attia E, Steinglass JE, Walsh BT, Wang Y, Wu P, Schreyer C, et al. (June 2019). "Olanzapine Versus Placebo in Adult Outpatients With Anorexia Nervosa: A Randomized Clinical Trial". The American Journal of Psychiatry. 176 (6): 449–456. doi:10.1176/appi.ajp.2018.18101125. PMC 7015155. PMID 30654643.
Sandhya L, Devi Sreenivasan N, Goenka L, Dubashi B, Kayal S, Solaiappan M, et al. (May 2023). "Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer". Journal of Clinical Oncology. 41 (14): 2617–2627. doi:10.1200/JCO.22.01997. PMID 36977285.
Hershenberg R, Gros DF, Brawman-Mintzer O (June 2014). "Role of atypical antipsychotics in the treatment of generalized anxiety disorder". CNS Drugs. 28 (6): 519–533. doi:10.1007/s40263-014-0162-6. PMID 24794100. S2CID 23429449.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, et al. (December 2017). "European guideline for the diagnosis and treatment of insomnia". Journal of Sleep Research. 26 (6): 675–700. doi:10.1111/jsr.12594. PMID 28875581. S2CID 10136993.
Morin AK (March 2014). "Off-label use of atypical antipsychotic agents for treatment of insomnia". Mental Health Clinician. 4 (2): 65–72. doi:10.9740/mhc.n190091.
Yoshida K, Takeuchi H (March 2021). "Dose-dependent effects of antipsychotics on efficacy and adverse effects in schizophrenia". Behavioural Brain Research. 402: 113098. doi:10.1016/j.bbr.2020.113098. PMID 33417992. S2CID 230507941.
Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuham A, Hindley G, et al. (January 2020). "Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis". The Lancet. Psychiatry. 7 (1): 64–77. doi:10.1016/S2215-0366(19)30416-X. PMC 7029416. PMID 31860457.
Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, et al. (August 2019). "British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update". Journal of Psychopharmacology. 33 (8): 923–947. doi:10.1177/0269881119855343. PMID 31271339. S2CID 195797603.
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, et al. (October 2017). "Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update". Journal of Clinical Oncology. 35 (28): 3240–3261. doi:10.1200/JCO.2017.74.4789. PMC 4876353. PMID 28759346.
Sutherland A, Naessens K, Plugge E, Ware L, Head K, Burton MJ, et al. (September 2018). "Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults". The Cochrane Database of Systematic Reviews. 2018 (9): CD012555. doi:10.1002/14651858.CD012555.pub2. PMC 6513437. PMID 30246876.
Schwartzberg L (March 2018). "Getting it right the first time: recent progress in optimizing antiemetic usage". Supportive Care in Cancer. 26 (Suppl 1): 19–27. doi:10.1007/s00520-018-4116-2. PMC 5876255. PMID 29556812.
Navari RM, Nagy CK, Gray SE (June 2013). "The use of olanzapine versus metoclopramide for the treatment of breakthrough chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy". Supportive Care in Cancer. 21 (6): 1655–1663. doi:10.1007/s00520-012-1710-6. PMID 23314603.
Yanai T, Iwasa S, Hashimoto H, Ohyanagi F, Takiguchi T, Takeda K, et al. (April 2018). "A double-blind randomized phase II dose-finding study of olanzapine 10 mg or 5 mg for the prophylaxis of emesis induced by highly emetogenic cisplatin-based chemotherapy". International Journal of Clinical Oncology. 23 (2): 382–388. doi:10.1007/s10147-017-1200-4. PMID 29039073.
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller TJ, Woods SW, et al. (May 2003). "The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design". Schizophrenia Research. 61 (1): 7–18. doi:10.1016/S0920-9964(02)00439-5. PMID 12648731. S2CID 1118339.
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T, Woods SW, et al. (May 2006). "Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis". The American Journal of Psychiatry. 163 (5): 790–799. doi:10.1176/appi.ajp.163.5.790. PMID 16648318.

drugs.com

"Drugs.com international listings for Olanzapine". Drugs.com. Retrieved 4 August 2015.
"Olanzapine, Olanzapine Pamoate Monograph for Professionals". Drugs.com. AHFS. Retrieved 24 December 2018.
"Olanzapine Monograph for Professionals - Drugs.com". Drugs.com. Retrieved 24 March 2017.

espacenet.com

worldwide.espacenet.com

US patent 5817655, Chakrabarti JK, Hotten TM, Tupper DE, "Methods of treatment using a thieno-benzodiazepine", issued 1998-10-06, assigned to Eli Lilly and Co Ltd.

eurekalert.org

"NIMH study to guide treatment choices for schizophrenia" (Press release). National Institute of Mental Health. 19 September 2005. Archived from the original on 15 October 2007. Retrieved 18 December 2006.

europa.eu

ema.europa.eu

"Zyprexa EPAR". European Medicines Agency (EMA). 27 September 1996. Retrieved 27 February 2024.
"Zypadhera". European Medicines Agency (EMA). 19 November 2008. Retrieved 26 October 2024.

fda.gov

accessdata.fda.gov

"NDA 21–520" (PDF). Food and Drug Administration. 24 December 2003. Retrieved 6 September 2009.
"NDA 20-592 / S-019" (PDF). Food and Drug Administration. 14 January 2004. Retrieved 6 September 2009.
"NDA 20-592" (PDF). Food and Drug Administration. 6 September 1996. Retrieved 6 September 2009.

nctr-crs.fda.gov

"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.

freedom-center.org

Ashton K (16 January 2007). "Activist Gagged for Drug Fact Leak in Lily Case" (PDF). Hampshire Daily Gazette.

handle.net

hdl.handle.net

World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

harvard.edu

ui.adsabs.harvard.edu

Brambilla G, Mattioli F, Martelli A (July 2009). "Genotoxic and carcinogenic effects of antipsychotics and antidepressants". Toxicology. 261 (3): 77–88. Bibcode:2009Toxgy.261...77B. doi:10.1016/j.tox.2009.04.056. PMID 19410629.
Reutzel-Edens SM, Bhardwaj RM (November 2020). "Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving". IUCrJ. 7 (Pt 6): 955–964. Bibcode:2020IUCrJ...7..955R. doi:10.1107/S2052252520012683. PMC 7642794. PMID 33209310.

in.gov.br

Anvisa (31 March 2023). "RDC Nº 784 – Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 – Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.

justice.gov

"Eli Lilly and Company Agrees to Pay $1.415 Billion to Resolve Allegations of Off-label Promotion of Zyprexa". U.S. Justice Department. 15 January 2009. Retrieved 9 July 2012.

jwatch.org

"NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals". www.jwatch.org. Retrieved 27 November 2022.

lilly.com

pi.lilly.com

"Olanzapine Prescribing Information" (PDF). Eli Lilly and Company. 19 March 2009. Retrieved 6 September 2009.

medicines.org.uk

"Zyprexa 10 mg coated tablets Summary of Product Characteristics (SmPC)". (emc). 2 February 2024. Retrieved 26 October 2024.

medicinescomplete.com

Joint Formulary Committee. "British National Formulary (online)". London: BMJ Group and Pharmaceutical. Retrieved 2 February 2020.

medsafe.govt.nz

"Hyperprolactinaemia With Antipsychotics". www.medsafe.govt.nz. Retrieved 10 October 2022.

medscape.com

reference.medscape.com

"Zyprexa, Zyprexa Relprevv (olanzapine) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Retrieved 26 November 2013.

medscape.com

Moyer P (25 October 2005). "CAFE Study Shows Varying Benefits Among Atypical Antipsychotics". Medscape Medical News. WebMD. Retrieved 3 December 2007.

nbcnews.com

"Lilly settles Zyprexa suit for $1.42 billion". NBCNews.com. Associated Press. 15 January 2009. Archived from the original on 31 January 2021.

nice.org.uk

"Overview | Psychosis and schizophrenia in adults: prevention and management | Guidance | NICE". www.nice.org.uk. 12 February 2014. Retrieved 30 November 2022.
"Bipolar disorder: the assessment and management of bipolar disorder in adults, children and young people in primary and secondary care". NICE. 24 September 2014. Retrieved 26 July 2016.

nih.gov

pubmed.ncbi.nlm.nih.gov

Kassahun K, Mattiuz E, Nyhart E, Obermeyer B, Gillespie T, Murphy A, et al. (January 1997). "Disposition and biotransformation of the antipsychotic agent olanzapine in humans". Drug Metabolism and Disposition. 25 (1): 81–93. PMID 9010634.
Callaghan JT, Bergstrom RF, Ptak LR, Beasley CM (September 1999). "Olanzapine. Pharmacokinetic and pharmacodynamic profile". Clinical Pharmacokinetics. 37 (3): 177–193. doi:10.2165/00003088-199937030-00001. PMID 10511917.
Mauri MC, Volonteri LS, Colasanti A, Fiorentini A, De Gaspari IF, Bareggi SR (2007). "Clinical pharmacokinetics of atypical antipsychotics: a critical review of the relationship between plasma concentrations and clinical response". Clinical Pharmacokinetics. 46 (5): 359–388. doi:10.2165/00003088-200746050-00001. PMID 17465637. S2CID 43859718.
Razvi Y, Chan S, McFarlane T, McKenzie E, Zaki P, DeAngelis C, et al. (January 2019). "ASCO, NCCN, MASCC/ESMO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in adult patients". Supportive Care in Cancer. 27 (1): 87–95. doi:10.1007/s00520-018-4464-y. PMID 30284039.
Sandhya L, Devi Sreenivasan N, Goenka L, Dubashi B, Kayal S, Solaiappan M, et al. (May 2023). "Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer". Journal of Clinical Oncology. 41 (14): 2617–2627. doi:10.1200/JCO.22.01997. PMID 36977285.
Thomas K, Saadabadi A (2023). "Olanzapine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30422498. Retrieved 20 November 2022.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, et al. (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019. S2CID 32085212.
Harvey RC, James AC, Shields GE (January 2016). "A Systematic Review and Network Meta-Analysis to Assess the Relative Efficacy of Antipsychotics for the Treatment of Positive and Negative Symptoms in Early-Onset Schizophrenia". CNS Drugs. 30 (1): 27–39. doi:10.1007/s40263-015-0308-1. PMID 26801655. S2CID 35702889.
Pagsberg AK, Tarp S, Glintborg D, Stenstrøm AD, Fink-Jensen A, Correll CU, et al. (March 2017). "Acute Antipsychotic Treatment of Children and Adolescents With Schizophrenia-Spectrum Disorders: A Systematic Review and Network Meta-Analysis". Journal of the American Academy of Child and Adolescent Psychiatry. 56 (3): 191–202. doi:10.1016/j.jaac.2016.12.013. PMID 28219485.
Osser DN, Roudsari MJ, Manschreck T (2013). "The psychopharmacology algorithm project at the Harvard South Shore Program: an update on schizophrenia". Harvard Review of Psychiatry. 21 (1): 18–40. doi:10.1097/HRP.0b013e31827fd915. PMID 23656760. S2CID 22523977.
Duggan L, Fenton M, Rathbone J, Dardennes R, El-Dosoky A, Indran S (April 2005). "Olanzapine for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (2): CD001359. doi:10.1002/14651858.CD001359.pub2. PMC 11781594. PMID 15846619.
Komossa K, Rummel-Kluge C, Hunger H, Schmid F, Schwarz S, Duggan L, et al. (March 2010). "Olanzapine versus other atypical antipsychotics for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (3): CD006654. doi:10.1002/14651858.CD006654.pub2. PMC 4169107. PMID 20238348.
McKeage K (February 2014). "Aripiprazole: a review of its use in the treatment of manic episodes in adolescents with bipolar I disorder". CNS Drugs. 28 (2): 171–183. doi:10.1007/s40263-013-0134-2. PMID 24399490. S2CID 199974.
Yatham LN, Kennedy SH, O'Donovan C, Parikh SV, MacQueen G, McIntyre RS, et al. (December 2006). "Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 2007". Bipolar Disorders. 8 (6): 721–739. doi:10.1111/j.1399-5618.2006.00432.x. PMID 17156158.
Dando S, Tohen M (March 2006). "Olanzapine - relapse prevention following mania". Journal of Psychopharmacology. 20 (2 Suppl): 31–38. doi:10.1177/1359786806063076. PMID 16551670. S2CID 34435730.
Selle V, Schalkwijk S, Vázquez GH, Baldessarini RJ (March 2014). "Treatments for acute bipolar depression: meta-analyses of placebo-controlled, monotherapy trials of anticonvulsants, lithium and antipsychotics". Pharmacopsychiatry. 47 (2): 43–52. doi:10.1055/s-0033-1363258. PMID 24549862.
Rasmussen SA, Chu SY, Kim SY, Schmid CH, Lau J (June 2008). "Maternal obesity and risk of neural tube defects: a metaanalysis". American Journal of Obstetrics and Gynecology. 198 (6): 611–619. doi:10.1016/j.ajog.2008.04.021. PMID 18538144.
McMahon DM, Liu J, Zhang H, Torres ME, Best RG (February 2013). "Maternal obesity, folate intake, and neural tube defects in offspring". Birth Defects Research. Part A, Clinical and Molecular Teratology. 97 (2): 115–122. doi:10.1002/bdra.23113. PMID 23404872.
Yeung EY, Chun S, Douglass A, Lau TE (8 May 2017). "Effect of atypical antipsychotics on body weight in geriatric psychiatric inpatients". SAGE Open Medicine. 5: 2050312117708711. doi:10.1177/2050312117708711. PMC 5431608. PMID 28540050.
Stöllberger C, Lutz W, Finsterer J (July 2009). "Heat-related side-effects of neurological and non-neurological medication may increase heatwave fatalities". European Journal of Neurology. 16 (7): 879–882. doi:10.1111/j.1468-1331.2009.02581.x. PMID 19453697. S2CID 25016607.
Ramankutty G (March 2002). "Olanzapine-induced destabilization of diabetes in the absence of weight gain". Acta Psychiatrica Scandinavica. 105 (3): 235–6, discussion 236–7. doi:10.1034/j.1600-0447.2002.2c257a.x. PMID 11939979. S2CID 5965031.
Lambert MT, Copeland LA, Sampson N, Duffy SA (July 2006). "New-onset type-2 diabetes associated with atypical antipsychotic medications". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30 (5): 919–923. doi:10.1016/j.pnpbp.2006.02.007. PMID 16581171. S2CID 24739534.
Wirshing DA, Wirshing WC, Kysar L, Berisford MA, Goldstein D, Pashdag J, et al. (June 1999). "Novel antipsychotics: comparison of weight gain liabilities". The Journal of Clinical Psychiatry. 60 (6): 358–363. doi:10.4088/JCP.v60n0602. PMID 10401912.
McEvoy JP, Lieberman JA, Perkins DO, Hamer RM, Gu H, Lazarus A, et al. (July 2007). "Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison". The American Journal of Psychiatry. 164 (7): 1050–1060. doi:10.1176/ajp.2007.164.7.1050. PMID 17606657.
Nemeroff CB (1997). "Dosing the antipsychotic medication olanzapine". The Journal of Clinical Psychiatry. 58 (Suppl 10): 45–49. PMID 9265916.
Chiu CC, Chen CH, Chen BY, Yu SH, Lu ML (August 2010). "The time-dependent change of insulin secretion in schizophrenic patients treated with olanzapine". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34 (6): 866–870. doi:10.1016/j.pnpbp.2010.04.003. PMID 20394794. S2CID 22445875.
Sacher J, Mossaheb N, Spindelegger C, Klein N, Geiss-Granadia T, Sauermann R, et al. (June 2008). "Effects of olanzapine and ziprasidone on glucose tolerance in healthy volunteers". Neuropsychopharmacology. 33 (7): 1633–1641. doi:10.1038/sj.npp.1301541. PMID 17712347.
Sowell M, Mukhopadhyay N, Cavazzoni P, Carlson C, Mudaliar S, Chinnapongse S, et al. (December 2003). "Evaluation of insulin sensitivity in healthy volunteers treated with olanzapine, risperidone, or placebo: a prospective, randomized study using the two-step hyperinsulinemic, euglycemic clamp". The Journal of Clinical Endocrinology and Metabolism. 88 (12): 5875–5880. doi:10.1210/jc.2002-021884. PMID 14671184.
de Haan L, van Amelsvoort T, Rosien K, Linszen D (September 2004). "Weight loss after switching from conventional olanzapine tablets to orally disintegrating olanzapine tablets". Psychopharmacology. 175 (3): 389–390. doi:10.1007/s00213-004-1951-2. PMID 15322727. S2CID 38751442.
Luedecke D, Schöttle D, Karow A, Lambert M, Naber D (January 2015). "Post-injection delirium/sedation syndrome in patients treated with olanzapine pamoate: mechanism, incidence, and management". CNS Drugs. 29 (1): 41–46. doi:10.1007/s40263-014-0216-9. PMID 25424243. S2CID 10928442.
Brambilla G, Mattioli F, Martelli A (July 2009). "Genotoxic and carcinogenic effects of antipsychotics and antidepressants". Toxicology. 261 (3): 77–88. Bibcode:2009Toxgy.261...77B. doi:10.1016/j.tox.2009.04.056. PMID 19410629.
Moncrieff J (July 2006). "Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse". Acta Psychiatrica Scandinavica. 114 (1): 3–13. doi:10.1111/j.1600-0447.2006.00787.x. PMID 16774655. S2CID 6267180.
Schwenger E, Dumontet J, Ensom MH (July 2011). "Does olanzapine warrant clinical pharmacokinetic monitoring in schizophrenia?". Clinical Pharmacokinetics. 50 (7): 415–428. doi:10.2165/11587240-000000000-00000. PMID 21651311. S2CID 21097041.
Yates G, Melon E (January 2024). "Trip-killers: a concerning practice associated with psychedelic drug use". Emerg Med J. 41 (2): 112–113. doi:10.1136/emermed-2023-213377. PMID 38123961.
Suran M (February 2024). "Study Finds Hundreds of Reddit Posts on "Trip-Killers" for Psychedelic Drugs". JAMA. 331 (8): 632–634. doi:10.1001/jama.2023.28257. PMID 38294772.
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, et al. (August 2008). "Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one". Bioorganic & Medicinal Chemistry. 16 (15): 7291–7301. doi:10.1016/j.bmc.2008.06.030. PMC 2664318. PMID 18595716.
Kroeze WK, Hufeisen SJ, Popadak BA, Renock SM, Steinberg S, Ernsberger P, et al. (March 2003). "H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs". Neuropsychopharmacology. 28 (3): 519–526. doi:10.1038/sj.npp.1300027. PMID 12629531.
Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, et al. (March 1996). "Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding". Psychopharmacology. 124 (1–2): 57–73. doi:10.1007/bf02245606. PMID 8935801. S2CID 12028979.
Davies MA, Setola V, Strachan RT, Sheffler DJ, Salay E, Hufeisen SJ, et al. (2006). "Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies". The Pharmacogenomics Journal. 6 (1): 42–51. doi:10.1038/sj.tpj.6500342. PMID 16314884.
Kongsamut S, Roehr JE, Cai J, Hartman HB, Weissensee P, Kerman LL, et al. (December 1996). "Iloperidone binding to human and rat dopamine and 5-HT receptors". European Journal of Pharmacology. 317 (2–3): 417–423. doi:10.1016/s0014-2999(96)00840-0. PMID 8997630.
Wainscott DB, Lucaites VL, Kursar JD, Baez M, Nelson DL (February 1996). "Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences". The Journal of Pharmacology and Experimental Therapeutics. 276 (2): 720–727. doi:10.1016/S0022-3565(25)12346-X. PMID 8632342.
Bymaster FP, Nelson DL, DeLapp NW, Falcone JF, Eckols K, Truex LL, et al. (May 1999). "Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro". Schizophrenia Research. 37 (1): 107–122. doi:10.1016/s0920-9964(98)00146-7. PMID 10227113. S2CID 19891653.
Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL (October 2003). "Muscarinic mechanisms of antipsychotic atypicality". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27 (7): 1125–1143. doi:10.1016/j.pnpbp.2003.09.008. PMID 14642972. S2CID 28536368.
Fernández J, Alonso JM, Andrés JI, Cid JM, Díaz A, Iturrino L, et al. (March 2005). "Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents". Journal of Medicinal Chemistry. 48 (6): 1709–1712. doi:10.1021/jm049632c. PMID 15771415.
Seeman P, Tallerico T (March 1998). "Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors". Molecular Psychiatry. 3 (2): 123–134. doi:10.1038/sj.mp.4000336. PMID 9577836.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, et al. (December 2005). "Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist". The Journal of Pharmacology and Experimental Therapeutics. 315 (3): 1278–1287. doi:10.1124/jpet.105.092155. PMID 16135699. S2CID 2247093.
Seeman P, Van Tol HH (October 1995). "Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand". European Journal of Pharmacology. 291 (2): 59–66. doi:10.1016/0922-4106(95)90125-6. PMID 8566176.
Arnt J, Skarsfeldt T (February 1998). "Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence". Neuropsychopharmacology. 18 (2): 63–101. doi:10.1016/S0893-133X(97)00112-7. PMID 9430133.
Tallman JF, Primus RJ, Brodbeck R, Cornfield L, Meade R, Woodruff K, et al. (August 1997). "I. NGD 94-1: identification of a novel, high-affinity antagonist at the human dopamine D4 receptor". The Journal of Pharmacology and Experimental Therapeutics. 282 (2): 1011–1019. doi:10.1016/S0022-3565(24)36884-3. PMID 9262370.
Bymaster FP, Calligaro DO, Falcone JF, Marsh RD, Moore NA, Tye NC, et al. (February 1996). "Radioreceptor binding profile of the atypical antipsychotic olanzapine". Neuropsychopharmacology. 14 (2): 87–96. doi:10.1016/0893-133X(94)00129-N. PMID 8822531.
Bymaster FP, Falcone JF (March 2000). "Decreased binding affinity of olanzapine and clozapine for human muscarinic receptors in intact clonal cells in physiological medium". European Journal of Pharmacology. 390 (3): 245–248. doi:10.1016/s0014-2999(00)00037-6. PMID 10708730.
Kongsamut S, Kang J, Chen XL, Roehr J, Rampe D (August 2002). "A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs". European Journal of Pharmacology. 450 (1): 37–41. doi:10.1016/s0014-2999(02)02074-5. PMID 12176106.
Citrome L, McEvoy JP, Todtenkopf MS, McDonnell D, Weiden PJ (September 2019). "A commentary on the efficacy of olanzapine for the treatment of schizophrenia: the past, present, and future". Neuropsychiatric Disease and Treatment. 15: 2559–2569. doi:10.2147/NDT.S209284. PMC 6733343. PMID 31564881.
Kapur S, Zipursky RB, Remington G, Jones C, DaSilva J, Wilson AA, et al. (July 1998). "5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation". The American Journal of Psychiatry. 155 (7): 921–928. doi:10.1176/ajp.155.7.921. PMID 9659858. S2CID 23678989.
Kessler RM, Ansari MS, Riccardi P, Li R, Jayathilake K, Dawant B, et al. (December 2005). "Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol". Neuropsychopharmacology. 30 (12): 2283–2289. doi:10.1038/sj.npp.1300836. PMID 16123775. S2CID 19688114.
Wang JS, Zhu HJ, Markowitz JS, Donovan JL, DeVane CL (September 2006). "Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein". Psychopharmacology. 187 (4): 415–423. doi:10.1007/s00213-006-0437-9. PMID 16810505. S2CID 13365903.
Moons T, de Roo M, Claes S, Dom G (August 2011). "Relationship between P-glycoprotein and second-generation antipsychotics". Pharmacogenomics. 12 (8): 1193–1211. doi:10.2217/pgs.11.55. PMID 21843066.
Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, et al. (May 2005). "Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia". Diabetes. 54 (5): 1552–1558. doi:10.2337/diabetes.54.5.1552. PMID 15855345.
Weston-Green K, Huang XF, Deng C (December 2013). "Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor". CNS Drugs. 27 (12): 1069–1080. doi:10.1007/s40263-013-0115-5. PMID 24114586. S2CID 5133679.
Silvestre JS, Prous J (June 2005). "Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes". Methods and Findings in Experimental and Clinical Pharmacology. 27 (5): 289–304. doi:10.1358/mf.2005.27.5.908643. PMID 16082416.
Van Oekelen D, Luyten WH, Leysen JE (April 2003). "5-HT2A and 5-HT2C receptors and their atypical regulation properties". Life Sciences. 72 (22): 2429–2449. doi:10.1016/s0024-3205(03)00141-3. PMID 12650852.
Reynolds GP, Hill MJ, Kirk SL (July 2006). "The 5-HT2C receptor and antipsychotic-induced weight gain - mechanisms and genetics". Journal of Psychopharmacology. 20 (4 Suppl): 15–18. doi:10.1177/1359786806066040. PMID 16785265. S2CID 19934754.
Wallace TJ, Zai CC, Brandl EJ, Müller DJ (18 August 2011). "Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain". Pharmacogenomics and Personalized Medicine. 4: 83–93. doi:10.2147/PGPM.S11866. PMC 3513221. PMID 23226055.
Reutzel-Edens SM, Bhardwaj RM (November 2020). "Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving". IUCrJ. 7 (Pt 6): 955–964. Bibcode:2020IUCrJ...7..955R. doi:10.1107/S2052252520012683. PMC 7642794. PMID 33209310.
Pillarella J, Higashi A, Alexander GC, Conti R (January 2012). "Trends in use of second-generation antipsychotics for treatment of bipolar disorder in the United States, 1998-2009". Psychiatric Services. 63 (1): 83–86. doi:10.1176/appi.ps.201100092. PMC 4594841. PMID 22227765.
Bobo WV, Shelton RC (2009). "Olanzapine and fluoxetine combination therapy for treatment-resistant depression: review of efficacy, safety, and study design issues". Neuropsychiatric Disease and Treatment. 5: 369–383. doi:10.2147/NDT.S5819. PMC 2706569. PMID 19590732.
Attia E, Steinglass JE, Walsh BT, Wang Y, Wu P, Schreyer C, et al. (June 2019). "Olanzapine Versus Placebo in Adult Outpatients With Anorexia Nervosa: A Randomized Clinical Trial". The American Journal of Psychiatry. 176 (6): 449–456. doi:10.1176/appi.ajp.2018.18101125. PMC 7015155. PMID 30654643.
Sandhya L, Devi Sreenivasan N, Goenka L, Dubashi B, Kayal S, Solaiappan M, et al. (May 2023). "Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer". Journal of Clinical Oncology. 41 (14): 2617–2627. doi:10.1200/JCO.22.01997. PMID 36977285.
Hershenberg R, Gros DF, Brawman-Mintzer O (June 2014). "Role of atypical antipsychotics in the treatment of generalized anxiety disorder". CNS Drugs. 28 (6): 519–533. doi:10.1007/s40263-014-0162-6. PMID 24794100. S2CID 23429449.
Narasimhan M, Bruce TO, Masand P (October 2007). "Review of olanzapine in the management of bipolar disorders". Neuropsychiatric Disease and Treatment. 3 (5): 579–587. PMC 2656294. PMID 19300587.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, et al. (December 2017). "European guideline for the diagnosis and treatment of insomnia". Journal of Sleep Research. 26 (6): 675–700. doi:10.1111/jsr.12594. PMID 28875581. S2CID 10136993.
Yoshida K, Takeuchi H (March 2021). "Dose-dependent effects of antipsychotics on efficacy and adverse effects in schizophrenia". Behavioural Brain Research. 402: 113098. doi:10.1016/j.bbr.2020.113098. PMID 33417992. S2CID 230507941.
Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuham A, Hindley G, et al. (January 2020). "Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis". The Lancet. Psychiatry. 7 (1): 64–77. doi:10.1016/S2215-0366(19)30416-X. PMC 7029416. PMID 31860457.
Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, et al. (August 2019). "British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update". Journal of Psychopharmacology. 33 (8): 923–947. doi:10.1177/0269881119855343. PMID 31271339. S2CID 195797603.
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, et al. (October 2017). "Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update". Journal of Clinical Oncology. 35 (28): 3240–3261. doi:10.1200/JCO.2017.74.4789. PMC 4876353. PMID 28759346.
Sutherland A, Naessens K, Plugge E, Ware L, Head K, Burton MJ, et al. (September 2018). "Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults". The Cochrane Database of Systematic Reviews. 2018 (9): CD012555. doi:10.1002/14651858.CD012555.pub2. PMC 6513437. PMID 30246876.
Schwartzberg L (March 2018). "Getting it right the first time: recent progress in optimizing antiemetic usage". Supportive Care in Cancer. 26 (Suppl 1): 19–27. doi:10.1007/s00520-018-4116-2. PMC 5876255. PMID 29556812.
Navari RM, Nagy CK, Gray SE (June 2013). "The use of olanzapine versus metoclopramide for the treatment of breakthrough chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy". Supportive Care in Cancer. 21 (6): 1655–1663. doi:10.1007/s00520-012-1710-6. PMID 23314603.
Yanai T, Iwasa S, Hashimoto H, Ohyanagi F, Takiguchi T, Takeda K, et al. (April 2018). "A double-blind randomized phase II dose-finding study of olanzapine 10 mg or 5 mg for the prophylaxis of emesis induced by highly emetogenic cisplatin-based chemotherapy". International Journal of Clinical Oncology. 23 (2): 382–388. doi:10.1007/s10147-017-1200-4. PMID 29039073.
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller TJ, Woods SW, et al. (May 2003). "The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design". Schizophrenia Research. 61 (1): 7–18. doi:10.1016/S0920-9964(02)00439-5. PMID 12648731. S2CID 1118339.
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T, Woods SW, et al. (May 2006). "Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis". The American Journal of Psychiatry. 163 (5): 790–799. doi:10.1176/appi.ajp.163.5.790. PMID 16648318.

ncbi.nlm.nih.gov

Thomas K, Saadabadi A (2023). "Olanzapine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30422498. Retrieved 20 November 2022.
Duggan L, Fenton M, Rathbone J, Dardennes R, El-Dosoky A, Indran S (April 2005). "Olanzapine for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (2): CD001359. doi:10.1002/14651858.CD001359.pub2. PMC 11781594. PMID 15846619.
Komossa K, Rummel-Kluge C, Hunger H, Schmid F, Schwarz S, Duggan L, et al. (March 2010). "Olanzapine versus other atypical antipsychotics for schizophrenia". The Cochrane Database of Systematic Reviews. 2013 (3): CD006654. doi:10.1002/14651858.CD006654.pub2. PMC 4169107. PMID 20238348.
Yeung EY, Chun S, Douglass A, Lau TE (8 May 2017). "Effect of atypical antipsychotics on body weight in geriatric psychiatric inpatients". SAGE Open Medicine. 5: 2050312117708711. doi:10.1177/2050312117708711. PMC 5431608. PMID 28540050.
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, et al. (August 2008). "Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one". Bioorganic & Medicinal Chemistry. 16 (15): 7291–7301. doi:10.1016/j.bmc.2008.06.030. PMC 2664318. PMID 18595716.
Citrome L, McEvoy JP, Todtenkopf MS, McDonnell D, Weiden PJ (September 2019). "A commentary on the efficacy of olanzapine for the treatment of schizophrenia: the past, present, and future". Neuropsychiatric Disease and Treatment. 15: 2559–2569. doi:10.2147/NDT.S209284. PMC 6733343. PMID 31564881.
Wallace TJ, Zai CC, Brandl EJ, Müller DJ (18 August 2011). "Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain". Pharmacogenomics and Personalized Medicine. 4: 83–93. doi:10.2147/PGPM.S11866. PMC 3513221. PMID 23226055.
Reutzel-Edens SM, Bhardwaj RM (November 2020). "Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving". IUCrJ. 7 (Pt 6): 955–964. Bibcode:2020IUCrJ...7..955R. doi:10.1107/S2052252520012683. PMC 7642794. PMID 33209310.
Pillarella J, Higashi A, Alexander GC, Conti R (January 2012). "Trends in use of second-generation antipsychotics for treatment of bipolar disorder in the United States, 1998-2009". Psychiatric Services. 63 (1): 83–86. doi:10.1176/appi.ps.201100092. PMC 4594841. PMID 22227765.
Bobo WV, Shelton RC (2009). "Olanzapine and fluoxetine combination therapy for treatment-resistant depression: review of efficacy, safety, and study design issues". Neuropsychiatric Disease and Treatment. 5: 369–383. doi:10.2147/NDT.S5819. PMC 2706569. PMID 19590732.
Attia E, Steinglass JE, Walsh BT, Wang Y, Wu P, Schreyer C, et al. (June 2019). "Olanzapine Versus Placebo in Adult Outpatients With Anorexia Nervosa: A Randomized Clinical Trial". The American Journal of Psychiatry. 176 (6): 449–456. doi:10.1176/appi.ajp.2018.18101125. PMC 7015155. PMID 30654643.
Narasimhan M, Bruce TO, Masand P (October 2007). "Review of olanzapine in the management of bipolar disorders". Neuropsychiatric Disease and Treatment. 3 (5): 579–587. PMC 2656294. PMID 19300587.
Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuham A, Hindley G, et al. (January 2020). "Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis". The Lancet. Psychiatry. 7 (1): 64–77. doi:10.1016/S2215-0366(19)30416-X. PMC 7029416. PMID 31860457.
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, et al. (October 2017). "Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update". Journal of Clinical Oncology. 35 (28): 3240–3261. doi:10.1200/JCO.2017.74.4789. PMC 4876353. PMID 28759346.
Sutherland A, Naessens K, Plugge E, Ware L, Head K, Burton MJ, et al. (September 2018). "Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults". The Cochrane Database of Systematic Reviews. 2018 (9): CD012555. doi:10.1002/14651858.CD012555.pub2. PMC 6513437. PMID 30246876.
Schwartzberg L (March 2018). "Getting it right the first time: recent progress in optimizing antiemetic usage". Supportive Care in Cancer. 26 (Suppl 1): 19–27. doi:10.1007/s00520-018-4116-2. PMC 5876255. PMID 29556812.

dailymed.nlm.nih.gov

"Zyprexa- olanzapine tablet; Zyprexa Zydis- olanzapine tablet, orally disintegrating; Zyprexa intramuscular- olanzapine injection, powder, for solution". DailyMed. 13 December 2023. Retrieved 17 October 2024.
"Symbyax- olanzapine and fluoxetine hydrochloride capsule". DailyMed. 21 April 2020. Retrieved 30 September 2020.
"DailyMed - Lybalvi- olanzapine and samidorphan l-malate tablet, film coated". DailyMed.

nps.org.au

"Olanzapine AN Tablets". NPS MedicineWise. May 2018. Retrieved 20 November 2022.

nytimes.com

Carey B (20 September 2005). "Little Difference Found in Schizophrenia Drugs". The New York Times. Retrieved 3 December 2007.
Walsh MW (5 September 2008). "Judge to Unseal Documents on the Eli Lilly Drug Zyprexa". The New York Times.
Berenson A (4 January 2007). "Mother Wonders if Psychosis Drug Helped Kill Son". The New York Times. Retrieved 21 May 2013.
Berenson A (5 January 2007). "Lilly Settles With 18,000 Over Zyprexa". The New York Times.
Berenson A (17 December 2006). "Eli Lilly Said to Play Down Risk of Top Pill". The New York Times. Retrieved 21 May 2013.
Harris G, Berenson A (14 January 2009). "Lilly Said to Be Near $1.4 Billion U.S. Settlement". The New York Times.
Berenson A (26 March 2008). "Lilly Settles Alaska Suit Over Zyprexa". The New York Times.
Berenson A (18 December 2006). "Drug Files Show Maker Promoted Unapproved Use". The New York Times. Retrieved 21 May 2013.

pharmacytimes.com

Horn JR, Hansten P (1 December 2008). "Drug Transporters: The Final Frontier for Drug Interactions". Pharmacy Times. Archived from the original on 11 February 2017. Retrieved 9 February 2017.

psychopharmacologyinstitute.com

"Olanzapine Indications: FDA-Approved Uses". psychopharmacologyinstitute.com. Retrieved 20 November 2022.

psychrights.org

PsychRights (2010). Law Project for Psychiatric Rights: Summary and Links to Relevant Documents in the Zyprexa Scandal. PsychRights. Retrieved 26 October 2021.

researchautism.net

"Olanzapine and Autism". Research Autism. 19 December 2017. Retrieved 9 June 2018.

rxlist.com

"Symbyax (Olanzapine and fluoxetine) drug overdose and contraindication information". RxList: The Internet Drug Index. WebMD. 2007. Archived from the original on 14 December 2007. Retrieved 3 December 2007.

semanticscholar.org

api.semanticscholar.org

Mauri MC, Volonteri LS, Colasanti A, Fiorentini A, De Gaspari IF, Bareggi SR (2007). "Clinical pharmacokinetics of atypical antipsychotics: a critical review of the relationship between plasma concentrations and clinical response". Clinical Pharmacokinetics. 46 (5): 359–388. doi:10.2165/00003088-200746050-00001. PMID 17465637. S2CID 43859718.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, et al. (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019. S2CID 32085212.
Harvey RC, James AC, Shields GE (January 2016). "A Systematic Review and Network Meta-Analysis to Assess the Relative Efficacy of Antipsychotics for the Treatment of Positive and Negative Symptoms in Early-Onset Schizophrenia". CNS Drugs. 30 (1): 27–39. doi:10.1007/s40263-015-0308-1. PMID 26801655. S2CID 35702889.
Osser DN, Roudsari MJ, Manschreck T (2013). "The psychopharmacology algorithm project at the Harvard South Shore Program: an update on schizophrenia". Harvard Review of Psychiatry. 21 (1): 18–40. doi:10.1097/HRP.0b013e31827fd915. PMID 23656760. S2CID 22523977.
McKeage K (February 2014). "Aripiprazole: a review of its use in the treatment of manic episodes in adolescents with bipolar I disorder". CNS Drugs. 28 (2): 171–183. doi:10.1007/s40263-013-0134-2. PMID 24399490. S2CID 199974.
Dando S, Tohen M (March 2006). "Olanzapine - relapse prevention following mania". Journal of Psychopharmacology. 20 (2 Suppl): 31–38. doi:10.1177/1359786806063076. PMID 16551670. S2CID 34435730.
Gupta S, Lakshmanan DA, Khastgir U, Nair R (2017). "Management of antipsychotic-induced hyperprolactinaemia". BJPsych Advances. 23 (4): 278–286. doi:10.1192/apt.bp.115.014928. ISSN 2056-4678. S2CID 80025501.
Stöllberger C, Lutz W, Finsterer J (July 2009). "Heat-related side-effects of neurological and non-neurological medication may increase heatwave fatalities". European Journal of Neurology. 16 (7): 879–882. doi:10.1111/j.1468-1331.2009.02581.x. PMID 19453697. S2CID 25016607.
Ramankutty G (March 2002). "Olanzapine-induced destabilization of diabetes in the absence of weight gain". Acta Psychiatrica Scandinavica. 105 (3): 235–6, discussion 236–7. doi:10.1034/j.1600-0447.2002.2c257a.x. PMID 11939979. S2CID 5965031.
Lambert MT, Copeland LA, Sampson N, Duffy SA (July 2006). "New-onset type-2 diabetes associated with atypical antipsychotic medications". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30 (5): 919–923. doi:10.1016/j.pnpbp.2006.02.007. PMID 16581171. S2CID 24739534.
Fulbright AR, Breedlove KT (2006). "Complete Resolution of Olanzapine-Induced Diabetic Ketoacidosis". Journal of Pharmacy Practice. 19 (4): 255–8. doi:10.1177/0897190006294180. S2CID 73047103.
Chiu CC, Chen CH, Chen BY, Yu SH, Lu ML (August 2010). "The time-dependent change of insulin secretion in schizophrenic patients treated with olanzapine". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34 (6): 866–870. doi:10.1016/j.pnpbp.2010.04.003. PMID 20394794. S2CID 22445875.
de Haan L, van Amelsvoort T, Rosien K, Linszen D (September 2004). "Weight loss after switching from conventional olanzapine tablets to orally disintegrating olanzapine tablets". Psychopharmacology. 175 (3): 389–390. doi:10.1007/s00213-004-1951-2. PMID 15322727. S2CID 38751442.
Luedecke D, Schöttle D, Karow A, Lambert M, Naber D (January 2015). "Post-injection delirium/sedation syndrome in patients treated with olanzapine pamoate: mechanism, incidence, and management". CNS Drugs. 29 (1): 41–46. doi:10.1007/s40263-014-0216-9. PMID 25424243. S2CID 10928442.
Moncrieff J (July 2006). "Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse". Acta Psychiatrica Scandinavica. 114 (1): 3–13. doi:10.1111/j.1600-0447.2006.00787.x. PMID 16774655. S2CID 6267180.
Schwenger E, Dumontet J, Ensom MH (July 2011). "Does olanzapine warrant clinical pharmacokinetic monitoring in schizophrenia?". Clinical Pharmacokinetics. 50 (7): 415–428. doi:10.2165/11587240-000000000-00000. PMID 21651311. S2CID 21097041.
Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, et al. (March 1996). "Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding". Psychopharmacology. 124 (1–2): 57–73. doi:10.1007/bf02245606. PMID 8935801. S2CID 12028979.
Bymaster FP, Nelson DL, DeLapp NW, Falcone JF, Eckols K, Truex LL, et al. (May 1999). "Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro". Schizophrenia Research. 37 (1): 107–122. doi:10.1016/s0920-9964(98)00146-7. PMID 10227113. S2CID 19891653.
Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL (October 2003). "Muscarinic mechanisms of antipsychotic atypicality". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27 (7): 1125–1143. doi:10.1016/j.pnpbp.2003.09.008. PMID 14642972. S2CID 28536368.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, et al. (December 2005). "Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist". The Journal of Pharmacology and Experimental Therapeutics. 315 (3): 1278–1287. doi:10.1124/jpet.105.092155. PMID 16135699. S2CID 2247093.
Kapur S, Zipursky RB, Remington G, Jones C, DaSilva J, Wilson AA, et al. (July 1998). "5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation". The American Journal of Psychiatry. 155 (7): 921–928. doi:10.1176/ajp.155.7.921. PMID 9659858. S2CID 23678989.
Kessler RM, Ansari MS, Riccardi P, Li R, Jayathilake K, Dawant B, et al. (December 2005). "Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol". Neuropsychopharmacology. 30 (12): 2283–2289. doi:10.1038/sj.npp.1300836. PMID 16123775. S2CID 19688114.
Wang JS, Zhu HJ, Markowitz JS, Donovan JL, DeVane CL (September 2006). "Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein". Psychopharmacology. 187 (4): 415–423. doi:10.1007/s00213-006-0437-9. PMID 16810505. S2CID 13365903.
Weston-Green K, Huang XF, Deng C (December 2013). "Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor". CNS Drugs. 27 (12): 1069–1080. doi:10.1007/s40263-013-0115-5. PMID 24114586. S2CID 5133679.
Reynolds GP, Hill MJ, Kirk SL (July 2006). "The 5-HT2C receptor and antipsychotic-induced weight gain - mechanisms and genetics". Journal of Psychopharmacology. 20 (4 Suppl): 15–18. doi:10.1177/1359786806066040. PMID 16785265. S2CID 19934754.
Hershenberg R, Gros DF, Brawman-Mintzer O (June 2014). "Role of atypical antipsychotics in the treatment of generalized anxiety disorder". CNS Drugs. 28 (6): 519–533. doi:10.1007/s40263-014-0162-6. PMID 24794100. S2CID 23429449.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, et al. (December 2017). "European guideline for the diagnosis and treatment of insomnia". Journal of Sleep Research. 26 (6): 675–700. doi:10.1111/jsr.12594. PMID 28875581. S2CID 10136993.
Yoshida K, Takeuchi H (March 2021). "Dose-dependent effects of antipsychotics on efficacy and adverse effects in schizophrenia". Behavioural Brain Research. 402: 113098. doi:10.1016/j.bbr.2020.113098. PMID 33417992. S2CID 230507941.
Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, et al. (August 2019). "British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update". Journal of Psychopharmacology. 33 (8): 923–947. doi:10.1177/0269881119855343. PMID 31271339. S2CID 195797603.
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller TJ, Woods SW, et al. (May 2003). "The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design". Schizophrenia Research. 61 (1): 7–18. doi:10.1016/S0920-9964(02)00439-5. PMID 12648731. S2CID 1118339.

shareholder.com

files.shareholder.com

"Lilly 2008 Annual Report" (PDF). Lilly. 2009. Archived from the original (PDF) on 1 October 2011. Retrieved 6 August 2009.

soton.ac.uk

eprints.soton.ac.uk

Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, et al. (August 2019). "British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update". Journal of Psychopharmacology. 33 (8): 923–947. doi:10.1177/0269881119855343. PMID 31271339. S2CID 195797603.

stutteringhelp.org

Scott L (Winter 2006). "Genetic and Neurological Factors in Stuttering". Stuttering Foundation of America.

tga.gov.au

ebs.tga.gov.au

"Product Information Olanzapine Sandoz 2.5mg/5mg/7.5mg/10mg/15mg/20mg Film-coated Tablets" (PDF). TGA eBusiness Services. Sandoz Pty Ltd. 8 June 2012. Retrieved 26 November 2013.

thezyprexapapers.com

Gottstein J (2021). The Zyreza Papers. Samizdat Health Writer's Cooperative 2021. Retrieved 26 October 2021.

timesonline.co.uk

Pagnamenta R (23 January 2007). "Eli Lilly was concerned by Zyprexa side-effects from 1998". The Times (London). Archived from the original on 20 February 2007.

unc.edu

pdsp.unc.edu

Roth BL, Driscol J. "PDSP K_i Database". Psychoactive Drug Screening Program (PDSP). University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. Retrieved 14 August 2017.

cdr.lib.unc.edu

McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T, Woods SW, et al. (May 2006). "Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis". The American Journal of Psychiatry. 163 (5): 790–799. doi:10.1176/appi.ajp.163.5.790. PMID 16648318.

web.archive.org

Anvisa (31 March 2023). "RDC Nº 784 – Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 – Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.
"The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
"Important Safety Information for Olanzapine". Zyprexa package insert. Eli Lilly & Company. 2007. Archived from the original on 23 November 2007. Retrieved 3 December 2007. Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. [...] ZYPREXA (olanzapine) is not approved for the treatment of elderly patients with dementia-related psychosis.
AstraZeneca Pharmaceuticals (4 April 2006). "Efficacy and Tolerability of Olanzapine, Quetiapine and Risperidone in the Treatment of First Episode Psychosis: A Randomised Double Blind 52 Week Comparison". AstraZeneca Clinical Trials. AstraZeneca PLC. Archived from the original on 13 November 2007. Retrieved 3 December 2007. At week 12, the olanzapine-treated group had more weight gain, a higher increase in [ body mass index ], and a higher proportion of patients with a BMI increase of at least 1 unit compared with the quetiapine and risperidone groups (p<=0.01).
"NIMH study to guide treatment choices for schizophrenia" (Press release). National Institute of Mental Health. 19 September 2005. Archived from the original on 15 October 2007. Retrieved 18 December 2006.
"Symbyax (Olanzapine and fluoxetine) drug overdose and contraindication information". RxList: The Internet Drug Index. WebMD. 2007. Archived from the original on 14 December 2007. Retrieved 3 December 2007.
Horn JR, Hansten P (1 December 2008). "Drug Transporters: The Final Frontier for Drug Interactions". Pharmacy Times. Archived from the original on 11 February 2017. Retrieved 9 February 2017.
"Lilly 2008 Annual Report" (PDF). Lilly. 2009. Archived from the original (PDF) on 1 October 2011. Retrieved 6 August 2009.
Pagnamenta R (23 January 2007). "Eli Lilly was concerned by Zyprexa side-effects from 1998". The Times (London). Archived from the original on 20 February 2007.
"Lilly settles Zyprexa suit for $1.42 billion". NBCNews.com. Associated Press. 15 January 2009. Archived from the original on 31 January 2021.

worldcat.org

search.worldcat.org

Gupta S, Lakshmanan DA, Khastgir U, Nair R (2017). "Management of antipsychotic-induced hyperprolactinaemia". BJPsych Advances. 23 (4): 278–286. doi:10.1192/apt.bp.115.014928. ISSN 2056-4678. S2CID 80025501.

zyprexa.com

"Important Safety Information for Olanzapine". Zyprexa package insert. Eli Lilly & Company. 2007. Archived from the original on 23 November 2007. Retrieved 3 December 2007. Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. [...] ZYPREXA (olanzapine) is not approved for the treatment of elderly patients with dementia-related psychosis.