PDK2 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "PDK2" in English language version.

Last modified: 18:15:22, 16 July 2025 (UTC)

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1818nih.gov

5^th place

1111doi.org

2^nd place

62ensembl.org

630^th place

326^th place

doi.org (Global: 2^nd place; English: 2^nd place)

Gudi R, Bowker-Kinley MM, Kedishvili NY, Zhao Y, Popov KM (Dec 1995). "Diversity of the pyruvate dehydrogenase kinase gene family in humans". The Journal of Biological Chemistry. 270 (48): 28989–28994. doi:10.1074/jbc.270.48.28989. PMID 7499431.
Knoechel TR, Tucker AD, Robinson CM, Phillips C, Taylor W, Bungay PJ, et al. (Jan 2006). "Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands". Biochemistry. 45 (2): 402–415. doi:10.1021/bi051402s. PMID 16401071.
Klyuyeva A, Tuganova A, Popov KM (Aug 2008). "Allosteric coupling in pyruvate dehydrogenase kinase 2". Biochemistry. 47 (32): 8358–8366. doi:10.1021/bi800631h. PMC 2568900. PMID 18627174.
Li J, Kato M, Chuang DT (Dec 2009). "Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate". The Journal of Biological Chemistry. 284 (49): 34458–34467. doi:10.1074/jbc.M109.065557. PMC 2797213. PMID 19833728.
Kolobova E, Tuganova A, Boulatnikov I, Popov KM (Aug 2001). "Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites". The Biochemical Journal. 358 (Pt 1): 69–77. doi:10.1042/0264-6021:3580069. PMC 1222033. PMID 11485553.
Dunford EC, Herbst EA, Jeoung NH, Gittings W, Inglis JG, Vandenboom R, et al. (Jun 2011). "PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300 (6): R1487–R1493. doi:10.1152/ajpregu.00498.2010. PMID 21411764.
Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, et al. (12 October 2012). "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species". The Journal of Biological Chemistry. 287 (42): 35153–35160. doi:10.1074/jbc.m112.400002. PMC 3471752. PMID 22910903.
Degenhardt T, Saramaki A, Malinen M, Rieck M, Vaisanen S, Huotari A, et al. (14 September 2007). "Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta". Journal of Molecular Biology. 372 (2): 341–355. doi:10.1016/j.jmb.2007.06.091. PMID 17669420.
Bajotto G, Murakami T, Nagasaki M, Qin B, Matsuo Y, Maeda K, et al. (March 2006). "Increased expression of hepatic pyruvate dehydrogenase kinases 2 and 4 in young and middle-aged Otsuka Long-Evans Tokushima Fatty rats: induction by elevated levels of free fatty acids". Metabolism: Clinical and Experimental. 55 (3): 317–323. doi:10.1016/j.metabol.2005.09.014. PMID 16483874.
Contractor T, Harris CR (15 January 2012). "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2". Cancer Research. 72 (2): 560–567. doi:10.1158/0008-5472.can-11-1215. PMID 22123926.
Sutendra G, Dromparis P, Kinnaird A, Stenson TH, Haromy A, Parker JM, et al. (28 March 2013). "Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer". Oncogene. 32 (13): 1638–1650. doi:10.1038/onc.2012.198. PMID 22614004.

ensembl.org (Global: 630^th place; English: 326^th place)

may2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000005882 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000038967 – Ensembl, May 2017

nih.gov (Global: 5^th place; English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Gudi R, Bowker-Kinley MM, Kedishvili NY, Zhao Y, Popov KM (Dec 1995). "Diversity of the pyruvate dehydrogenase kinase gene family in humans". The Journal of Biological Chemistry. 270 (48): 28989–28994. doi:10.1074/jbc.270.48.28989. PMID 7499431.
Knoechel TR, Tucker AD, Robinson CM, Phillips C, Taylor W, Bungay PJ, et al. (Jan 2006). "Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands". Biochemistry. 45 (2): 402–415. doi:10.1021/bi051402s. PMID 16401071.
Klyuyeva A, Tuganova A, Popov KM (Aug 2008). "Allosteric coupling in pyruvate dehydrogenase kinase 2". Biochemistry. 47 (32): 8358–8366. doi:10.1021/bi800631h. PMC 2568900. PMID 18627174.
Li J, Kato M, Chuang DT (Dec 2009). "Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate". The Journal of Biological Chemistry. 284 (49): 34458–34467. doi:10.1074/jbc.M109.065557. PMC 2797213. PMID 19833728.
Kolobova E, Tuganova A, Boulatnikov I, Popov KM (Aug 2001). "Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites". The Biochemical Journal. 358 (Pt 1): 69–77. doi:10.1042/0264-6021:3580069. PMC 1222033. PMID 11485553.
Dunford EC, Herbst EA, Jeoung NH, Gittings W, Inglis JG, Vandenboom R, et al. (Jun 2011). "PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300 (6): R1487–R1493. doi:10.1152/ajpregu.00498.2010. PMID 21411764.
Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, et al. (12 October 2012). "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species". The Journal of Biological Chemistry. 287 (42): 35153–35160. doi:10.1074/jbc.m112.400002. PMC 3471752. PMID 22910903.
Degenhardt T, Saramaki A, Malinen M, Rieck M, Vaisanen S, Huotari A, et al. (14 September 2007). "Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta". Journal of Molecular Biology. 372 (2): 341–355. doi:10.1016/j.jmb.2007.06.091. PMID 17669420.
Bajotto G, Murakami T, Nagasaki M, Qin B, Matsuo Y, Maeda K, et al. (March 2006). "Increased expression of hepatic pyruvate dehydrogenase kinases 2 and 4 in young and middle-aged Otsuka Long-Evans Tokushima Fatty rats: induction by elevated levels of free fatty acids". Metabolism: Clinical and Experimental. 55 (3): 317–323. doi:10.1016/j.metabol.2005.09.014. PMID 16483874.
Contractor T, Harris CR (15 January 2012). "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2". Cancer Research. 72 (2): 560–567. doi:10.1158/0008-5472.can-11-1215. PMID 22123926.
Sutendra G, Dromparis P, Kinnaird A, Stenson TH, Haromy A, Parker JM, et al. (28 March 2013). "Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer". Oncogene. 32 (13): 1638–1650. doi:10.1038/onc.2012.198. PMID 22614004.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: PDK2 pyruvate dehydrogenase kinase, isozyme 2".
Klyuyeva A, Tuganova A, Popov KM (Aug 2008). "Allosteric coupling in pyruvate dehydrogenase kinase 2". Biochemistry. 47 (32): 8358–8366. doi:10.1021/bi800631h. PMC 2568900. PMID 18627174.
Li J, Kato M, Chuang DT (Dec 2009). "Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate". The Journal of Biological Chemistry. 284 (49): 34458–34467. doi:10.1074/jbc.M109.065557. PMC 2797213. PMID 19833728.
Kolobova E, Tuganova A, Boulatnikov I, Popov KM (Aug 2001). "Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites". The Biochemical Journal. 358 (Pt 1): 69–77. doi:10.1042/0264-6021:3580069. PMC 1222033. PMID 11485553.
Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, et al. (12 October 2012). "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species". The Journal of Biological Chemistry. 287 (42): 35153–35160. doi:10.1074/jbc.m112.400002. PMC 3471752. PMID 22910903.