PFKFB3 (English Wikipedia)
Analysis of information sources in references of the Wikipedia article "PFKFB3" in English language version.
refsWebsite
Global rank
English rank
18th place
17th place
11th place
8th place
1,626th place
1,007th place
102nd place
76th place
1,010th place
612th place
5,225th place
4,062nd place
1st place
1st place
clinicaltrials.gov (Global: 5,225th place; English: 4,062nd place)
creativecommons.org (Global: 1,010th place; English: 612th place)
- Burmistrova O, Olias-Arjona A, Lapresa R, Jimenez-Blasco D, Eremeeva T, Shishov D, et al. (August 2019). "Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice". Scientific Reports. 9 (1): 11670. Bibcode:2019NatSR...911670B. doi:10.1038/s41598-019-48196-z. PMC 6691133. PMID 31406177.
Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
doi.org (Global: 2nd place; English: 2nd place)
- Nicholl J, Hamilton JA, Sutherland GR, Sutherland RL, Watts CK (April 1997). "The third human isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) map position 10p14-p15". Chromosome Research. 5 (2): 150. doi:10.1023/A:1018482511456. PMID 9146922. S2CID 34088792.
- Manzano A, Rosa JL, Ventura F, Pérez JX, Nadal M, Estivill X, et al. (Mar 1999). "Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2, 6-bisphosphatase gene (PFKFB3)". Cytogenetics and Cell Genetics. 83 (3–4): 214–7. doi:10.1159/000015181. PMID 10072580. S2CID 23221556.
- Mahlknecht U, Chesney J, Hoelzer D, Bucala R (October 2003). "Cloning and chromosomal characterization of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 gene (PFKFB3, iPFK2)". International Journal of Oncology. 23 (4): 883–91. doi:10.3892/ijo.23.4.883. PMID 12963966.
- Kessler R, Eschrich K (March 2001). "Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain". Brain Research. Molecular Brain Research. 87 (2): 190–5. doi:10.1016/s0169-328x(01)00014-6. PMID 11245921.
- Navarro-Sabaté A, Manzano A, Riera L, Rosa JL, Ventura F, Bartrons R (February 2001). "The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure". Gene. 264 (1): 131–8. doi:10.1016/S0378-1119(00)00591-6. PMID 11245987.
- Kim SG, Manes NP, El-Maghrabi MR, Lee YH (February 2006). "Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy". The Journal of Biological Chemistry. 281 (5): 2939–44. doi:10.1074/jbc.M511019200. PMID 16316985.
- Sakakibara R, Kato M, Okamura N, Nakagawa T, Komada Y, Tominaga N, et al. (July 1997). "Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase". Journal of Biochemistry. 122 (1): 122–8. doi:10.1093/oxfordjournals.jbchem.a021719. PMID 9276680.
- Magistretti PJ, Sorg O, Yu N, Martin JL, Pellerin L (1993). "Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells". Dev Neurosci. 15 (3–51): 306–12. doi:10.1159/000111349. PMID 7805583.
- Herrero-Mendez A, Almeida A, Fernández E, Maestre C, Moncada S, Bolaños JP (June 2009). "The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1". Nat Cell Biol. 11 (6): 747–52. doi:10.1038/ncb1881. PMID 19448625. S2CID 19519317.
- Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolaños JP (October 2012). "Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration". Cell Death Differ. 19 (10): 1582–9. doi:10.1038/cdd.2012.33. PMC 3438489. PMID 22421967.
- Burmistrova O, Olias-Arjona A, Lapresa R, Jimenez-Blasco D, Eremeeva T, Shishov D, et al. (August 2019). "Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice". Scientific Reports. 9 (1): 11670. Bibcode:2019NatSR...911670B. doi:10.1038/s41598-019-48196-z. PMC 6691133. PMID 31406177. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
- Warburg O (February 1956). "On the origin of cancer cells". Science. 123 (3191): 309–14. Bibcode:1956Sci...123..309W. doi:10.1126/science.123.3191.309. PMID 13298683.
- Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, et al. (March 2014). "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway". Nature Communications. 5: 3480. Bibcode:2014NatCo...5.3480Y. doi:10.1038/ncomms4480. PMC 3959213. PMID 24633012.
- Minchenko A, Leshchinsky I, Opentanova I, Sang N, Srinivas V, Armstead V, Caro J (February 2002). "Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect". The Journal of Biological Chemistry. 277 (8): 6183–7. doi:10.1074/jbc.M110978200. PMC 4518871. PMID 11744734.
- Obach M, Navarro-Sabaté A, Caro J, Kong X, Duran J, Gómez M, et al. (December 2004). "6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia". The Journal of Biological Chemistry. 279 (51): 53562–70. doi:10.1074/jbc.M406096200. hdl:2445/181308. PMID 15466858.
- Yalcin A, Clem BF, Simmons A, Lane A, Nelson K, Clem AL, et al. (September 2009). "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases". The Journal of Biological Chemistry. 284 (36): 24223–32. doi:10.1074/jbc.M109.016816. PMC 2782016. PMID 19473963.
- Yalcin A, Clem BF, Imbert-Fernandez Y, Ozcan SC, Peker S, O'Neal J, et al. (July 2014). "6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27". Cell Death & Disease. 5 (7): e1337. doi:10.1038/cddis.2014.292. PMC 4123086. PMID 25032860.
- Savvidis C, Koutsilieris M (December 2012). "Circadian rhythm disruption in cancer biology". Molecular Medicine. 18 (1): 1249–60. doi:10.2119/molmed.2012.00077. PMC 3521792. PMID 22811066.
- Chen L, Zhao J, Tang Q, Li H, Zhang C, Yu R, et al. (April 2016). "PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs". Scientific Reports. 6 24324. Bibcode:2016NatSR...624324C. doi:10.1038/srep24324. PMC 4832144. PMID 27079271.
- Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, et al. (April 2015). "Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3". Journal of Medicinal Chemistry. 58 (8): 3611–25. doi:10.1021/acs.jmedchem.5b00352. PMID 25849762.
- Novellasdemunt L, Obach M, Millán-Ariño L, Manzano A, Ventura F, Rosa JL, et al. (March 2012). "Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells". The Biochemical Journal. 442 (2): 345–56. doi:10.1042/BJ20111418. hdl:10261/87967. PMID 22115192.
- De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, et al. (August 2013). "Role of PFKFB3-driven glycolysis in vessel sprouting". Cell. 154 (3): 651–63. doi:10.1016/j.cell.2013.06.037. PMID 23911327.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Clem BF, O'Neal J, Tapolsky G, Clem AL, Imbert-Fernandez Y, Kerr DA, et al. (August 2013). "Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer". Molecular Cancer Therapeutics. 12 (8): 1461–70. doi:10.1158/1535-7163.MCT-13-0097. PMC 3742633. PMID 23674815.
- Gustafsson NM, Färnegårdh K, Bonagas N, Ninou AH, Groth P, Wiita E, et al. (September 2018). "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination". Nature Communications. 9 (1): 3872. Bibcode:2018NatCo...9.3872G. doi:10.1038/s41467-018-06287-x. PMC 6155239. PMID 30250201.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Yang Z, Goronzy JJ, Weyand CM (February 2014). "The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy". Autophagy. 10 (2): 382–3. doi:10.4161/auto.27345. PMC 5079104. PMID 24351650.
- Yang Z, Fujii H, Mohan SV, Goronzy JJ, Weyand CM (September 2013). "Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells". The Journal of Experimental Medicine. 210 (10): 2119–34. doi:10.1084/jem.20130252. PMC 3782046. PMID 24043759.
- Trefely S, Khoo PS, Krycer JR, Chaudhuri R, Fazakerley DJ, Parker BL, et al. (October 2015). "Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway". The Journal of Biological Chemistry. 290 (43): 25834–46. doi:10.1074/jbc.M115.658815. PMC 4646237. PMID 26342081.
- Atsumi T, Nishio T, Niwa H, Takeuchi J, Bando H, Shimizu C, et al. (December 2005). "Expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation". Diabetes. 54 (12): 3349–57. doi:10.2337/diabetes.54.12.3349. PMID 16306349.
- Novellasdemunt L, Bultot L, Manzano A, Ventura F, Rosa JL, Vertommen D, et al. (June 2013). "PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli". The Biochemical Journal. 452 (3): 531–43. doi:10.1042/bj20121886. PMID 23548149.
- Bolaños JP (June 2013). "Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3". The Biochemical Journal. 452 (3): e7-9. doi:10.1042/bj20130560. PMID 23725459.
ensembl.org (Global: 1,626th place; English: 1,007th place)
May2017.archive.ensembl.org
- GRCh38: Ensembl release 89: ENSG00000170525 – Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000026773 – Ensembl, May 2017
handle.net (Global: 102nd place; English: 76th place)
hdl.handle.net
- Obach M, Navarro-Sabaté A, Caro J, Kong X, Duran J, Gómez M, et al. (December 2004). "6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia". The Journal of Biological Chemistry. 279 (51): 53562–70. doi:10.1074/jbc.M406096200. hdl:2445/181308. PMID 15466858.
- Novellasdemunt L, Obach M, Millán-Ariño L, Manzano A, Ventura F, Rosa JL, et al. (March 2012). "Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells". The Biochemical Journal. 442 (2): 345–56. doi:10.1042/BJ20111418. hdl:10261/87967. PMID 22115192.
harvard.edu (Global: 18th place; English: 17th place)
ui.adsabs.harvard.edu
- Burmistrova O, Olias-Arjona A, Lapresa R, Jimenez-Blasco D, Eremeeva T, Shishov D, et al. (August 2019). "Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice". Scientific Reports. 9 (1): 11670. Bibcode:2019NatSR...911670B. doi:10.1038/s41598-019-48196-z. PMC 6691133. PMID 31406177. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
- Warburg O (February 1956). "On the origin of cancer cells". Science. 123 (3191): 309–14. Bibcode:1956Sci...123..309W. doi:10.1126/science.123.3191.309. PMID 13298683.
- Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, et al. (March 2014). "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway". Nature Communications. 5: 3480. Bibcode:2014NatCo...5.3480Y. doi:10.1038/ncomms4480. PMC 3959213. PMID 24633012.
- Chen L, Zhao J, Tang Q, Li H, Zhang C, Yu R, et al. (April 2016). "PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs". Scientific Reports. 6 24324. Bibcode:2016NatSR...624324C. doi:10.1038/srep24324. PMC 4832144. PMID 27079271.
- Gustafsson NM, Färnegårdh K, Bonagas N, Ninou AH, Groth P, Wiita E, et al. (September 2018). "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination". Nature Communications. 9 (1): 3872. Bibcode:2018NatCo...9.3872G. doi:10.1038/s41467-018-06287-x. PMC 6155239. PMID 30250201.
nih.gov (Global: 4th place; English: 4th place)
pubmed.ncbi.nlm.nih.gov
- Nicholl J, Hamilton JA, Sutherland GR, Sutherland RL, Watts CK (April 1997). "The third human isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) map position 10p14-p15". Chromosome Research. 5 (2): 150. doi:10.1023/A:1018482511456. PMID 9146922. S2CID 34088792.
- Manzano A, Rosa JL, Ventura F, Pérez JX, Nadal M, Estivill X, et al. (Mar 1999). "Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2, 6-bisphosphatase gene (PFKFB3)". Cytogenetics and Cell Genetics. 83 (3–4): 214–7. doi:10.1159/000015181. PMID 10072580. S2CID 23221556.
- Mahlknecht U, Chesney J, Hoelzer D, Bucala R (October 2003). "Cloning and chromosomal characterization of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 gene (PFKFB3, iPFK2)". International Journal of Oncology. 23 (4): 883–91. doi:10.3892/ijo.23.4.883. PMID 12963966.
- Kessler R, Eschrich K (March 2001). "Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain". Brain Research. Molecular Brain Research. 87 (2): 190–5. doi:10.1016/s0169-328x(01)00014-6. PMID 11245921.
- Navarro-Sabaté A, Manzano A, Riera L, Rosa JL, Ventura F, Bartrons R (February 2001). "The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure". Gene. 264 (1): 131–8. doi:10.1016/S0378-1119(00)00591-6. PMID 11245987.
- Kim SG, Manes NP, El-Maghrabi MR, Lee YH (February 2006). "Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy". The Journal of Biological Chemistry. 281 (5): 2939–44. doi:10.1074/jbc.M511019200. PMID 16316985.
- Sakakibara R, Kato M, Okamura N, Nakagawa T, Komada Y, Tominaga N, et al. (July 1997). "Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase". Journal of Biochemistry. 122 (1): 122–8. doi:10.1093/oxfordjournals.jbchem.a021719. PMID 9276680.
- Magistretti PJ, Sorg O, Yu N, Martin JL, Pellerin L (1993). "Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells". Dev Neurosci. 15 (3–51): 306–12. doi:10.1159/000111349. PMID 7805583.
- Herrero-Mendez A, Almeida A, Fernández E, Maestre C, Moncada S, Bolaños JP (June 2009). "The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1". Nat Cell Biol. 11 (6): 747–52. doi:10.1038/ncb1881. PMID 19448625. S2CID 19519317.
- Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolaños JP (October 2012). "Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration". Cell Death Differ. 19 (10): 1582–9. doi:10.1038/cdd.2012.33. PMC 3438489. PMID 22421967.
- Burmistrova O, Olias-Arjona A, Lapresa R, Jimenez-Blasco D, Eremeeva T, Shishov D, et al. (August 2019). "Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice". Scientific Reports. 9 (1): 11670. Bibcode:2019NatSR...911670B. doi:10.1038/s41598-019-48196-z. PMC 6691133. PMID 31406177. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
- Warburg O (February 1956). "On the origin of cancer cells". Science. 123 (3191): 309–14. Bibcode:1956Sci...123..309W. doi:10.1126/science.123.3191.309. PMID 13298683.
- Atsumi T, Chesney J, Metz C, Leng L, Donnelly S, Makita Z, et al. (October 2002). "High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers". Cancer Research. 62 (20): 5881–7. PMID 12384552.
- Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, et al. (March 2014). "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway". Nature Communications. 5: 3480. Bibcode:2014NatCo...5.3480Y. doi:10.1038/ncomms4480. PMC 3959213. PMID 24633012.
- Minchenko A, Leshchinsky I, Opentanova I, Sang N, Srinivas V, Armstead V, Caro J (February 2002). "Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect". The Journal of Biological Chemistry. 277 (8): 6183–7. doi:10.1074/jbc.M110978200. PMC 4518871. PMID 11744734.
- Obach M, Navarro-Sabaté A, Caro J, Kong X, Duran J, Gómez M, et al. (December 2004). "6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia". The Journal of Biological Chemistry. 279 (51): 53562–70. doi:10.1074/jbc.M406096200. hdl:2445/181308. PMID 15466858.
- Yalcin A, Clem BF, Simmons A, Lane A, Nelson K, Clem AL, et al. (September 2009). "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases". The Journal of Biological Chemistry. 284 (36): 24223–32. doi:10.1074/jbc.M109.016816. PMC 2782016. PMID 19473963.
- Yalcin A, Clem BF, Imbert-Fernandez Y, Ozcan SC, Peker S, O'Neal J, et al. (July 2014). "6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27". Cell Death & Disease. 5 (7): e1337. doi:10.1038/cddis.2014.292. PMC 4123086. PMID 25032860.
- Savvidis C, Koutsilieris M (December 2012). "Circadian rhythm disruption in cancer biology". Molecular Medicine. 18 (1): 1249–60. doi:10.2119/molmed.2012.00077. PMC 3521792. PMID 22811066.
- Chen L, Zhao J, Tang Q, Li H, Zhang C, Yu R, et al. (April 2016). "PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs". Scientific Reports. 6 24324. Bibcode:2016NatSR...624324C. doi:10.1038/srep24324. PMC 4832144. PMID 27079271.
- Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, et al. (April 2015). "Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3". Journal of Medicinal Chemistry. 58 (8): 3611–25. doi:10.1021/acs.jmedchem.5b00352. PMID 25849762.
- Novellasdemunt L, Obach M, Millán-Ariño L, Manzano A, Ventura F, Rosa JL, et al. (March 2012). "Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells". The Biochemical Journal. 442 (2): 345–56. doi:10.1042/BJ20111418. hdl:10261/87967. PMID 22115192.
- De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, et al. (August 2013). "Role of PFKFB3-driven glycolysis in vessel sprouting". Cell. 154 (3): 651–63. doi:10.1016/j.cell.2013.06.037. PMID 23911327.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Clem BF, O'Neal J, Tapolsky G, Clem AL, Imbert-Fernandez Y, Kerr DA, et al. (August 2013). "Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer". Molecular Cancer Therapeutics. 12 (8): 1461–70. doi:10.1158/1535-7163.MCT-13-0097. PMC 3742633. PMID 23674815.
- Gustafsson NM, Färnegårdh K, Bonagas N, Ninou AH, Groth P, Wiita E, et al. (September 2018). "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination". Nature Communications. 9 (1): 3872. Bibcode:2018NatCo...9.3872G. doi:10.1038/s41467-018-06287-x. PMC 6155239. PMID 30250201.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Yang Z, Goronzy JJ, Weyand CM (February 2014). "The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy". Autophagy. 10 (2): 382–3. doi:10.4161/auto.27345. PMC 5079104. PMID 24351650.
- Yang Z, Fujii H, Mohan SV, Goronzy JJ, Weyand CM (September 2013). "Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells". The Journal of Experimental Medicine. 210 (10): 2119–34. doi:10.1084/jem.20130252. PMC 3782046. PMID 24043759.
- Trefely S, Khoo PS, Krycer JR, Chaudhuri R, Fazakerley DJ, Parker BL, et al. (October 2015). "Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway". The Journal of Biological Chemistry. 290 (43): 25834–46. doi:10.1074/jbc.M115.658815. PMC 4646237. PMID 26342081.
- Atsumi T, Nishio T, Niwa H, Takeuchi J, Bando H, Shimizu C, et al. (December 2005). "Expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation". Diabetes. 54 (12): 3349–57. doi:10.2337/diabetes.54.12.3349. PMID 16306349.
- Novellasdemunt L, Bultot L, Manzano A, Ventura F, Rosa JL, Vertommen D, et al. (June 2013). "PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli". The Biochemical Journal. 452 (3): 531–43. doi:10.1042/bj20121886. PMID 23548149.
- Bolaños JP (June 2013). "Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3". The Biochemical Journal. 452 (3): e7-9. doi:10.1042/bj20130560. PMID 23725459.
ncbi.nlm.nih.gov
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3".
- Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolaños JP (October 2012). "Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration". Cell Death Differ. 19 (10): 1582–9. doi:10.1038/cdd.2012.33. PMC 3438489. PMID 22421967.
- Burmistrova O, Olias-Arjona A, Lapresa R, Jimenez-Blasco D, Eremeeva T, Shishov D, et al. (August 2019). "Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice". Scientific Reports. 9 (1): 11670. Bibcode:2019NatSR...911670B. doi:10.1038/s41598-019-48196-z. PMC 6691133. PMID 31406177. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
- Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, et al. (March 2014). "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway". Nature Communications. 5: 3480. Bibcode:2014NatCo...5.3480Y. doi:10.1038/ncomms4480. PMC 3959213. PMID 24633012.
- Minchenko A, Leshchinsky I, Opentanova I, Sang N, Srinivas V, Armstead V, Caro J (February 2002). "Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect". The Journal of Biological Chemistry. 277 (8): 6183–7. doi:10.1074/jbc.M110978200. PMC 4518871. PMID 11744734.
- Yalcin A, Clem BF, Simmons A, Lane A, Nelson K, Clem AL, et al. (September 2009). "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases". The Journal of Biological Chemistry. 284 (36): 24223–32. doi:10.1074/jbc.M109.016816. PMC 2782016. PMID 19473963.
- Yalcin A, Clem BF, Imbert-Fernandez Y, Ozcan SC, Peker S, O'Neal J, et al. (July 2014). "6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27". Cell Death & Disease. 5 (7): e1337. doi:10.1038/cddis.2014.292. PMC 4123086. PMID 25032860.
- Savvidis C, Koutsilieris M (December 2012). "Circadian rhythm disruption in cancer biology". Molecular Medicine. 18 (1): 1249–60. doi:10.2119/molmed.2012.00077. PMC 3521792. PMID 22811066.
- Chen L, Zhao J, Tang Q, Li H, Zhang C, Yu R, et al. (April 2016). "PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs". Scientific Reports. 6 24324. Bibcode:2016NatSR...624324C. doi:10.1038/srep24324. PMC 4832144. PMID 27079271.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Clem BF, O'Neal J, Tapolsky G, Clem AL, Imbert-Fernandez Y, Kerr DA, et al. (August 2013). "Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer". Molecular Cancer Therapeutics. 12 (8): 1461–70. doi:10.1158/1535-7163.MCT-13-0097. PMC 3742633. PMID 23674815.
- Gustafsson NM, Färnegårdh K, Bonagas N, Ninou AH, Groth P, Wiita E, et al. (September 2018). "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination". Nature Communications. 9 (1): 3872. Bibcode:2018NatCo...9.3872G. doi:10.1038/s41467-018-06287-x. PMC 6155239. PMID 30250201.
- Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, et al. (January 2014). "Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism". Cancer & Metabolism. 2 (1): 2. doi:10.1186/2049-3002-2-2. PMC 3913946. PMID 24451478.
- Yang Z, Goronzy JJ, Weyand CM (February 2014). "The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy". Autophagy. 10 (2): 382–3. doi:10.4161/auto.27345. PMC 5079104. PMID 24351650.
- Yang Z, Fujii H, Mohan SV, Goronzy JJ, Weyand CM (September 2013). "Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells". The Journal of Experimental Medicine. 210 (10): 2119–34. doi:10.1084/jem.20130252. PMC 3782046. PMID 24043759.
- Trefely S, Khoo PS, Krycer JR, Chaudhuri R, Fazakerley DJ, Parker BL, et al. (October 2015). "Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway". The Journal of Biological Chemistry. 290 (43): 25834–46. doi:10.1074/jbc.M115.658815. PMC 4646237. PMID 26342081.
semanticscholar.org (Global: 11th place; English: 8th place)
api.semanticscholar.org
- Nicholl J, Hamilton JA, Sutherland GR, Sutherland RL, Watts CK (April 1997). "The third human isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) map position 10p14-p15". Chromosome Research. 5 (2): 150. doi:10.1023/A:1018482511456. PMID 9146922. S2CID 34088792.
- Manzano A, Rosa JL, Ventura F, Pérez JX, Nadal M, Estivill X, et al. (Mar 1999). "Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2, 6-bisphosphatase gene (PFKFB3)". Cytogenetics and Cell Genetics. 83 (3–4): 214–7. doi:10.1159/000015181. PMID 10072580. S2CID 23221556.
- Herrero-Mendez A, Almeida A, Fernández E, Maestre C, Moncada S, Bolaños JP (June 2009). "The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1". Nat Cell Biol. 11 (6): 747–52. doi:10.1038/ncb1881. PMID 19448625. S2CID 19519317.
web.archive.org (Global: 1st place; English: 1st place)
- "Disappointing cancer drug trials jeopardize future of local biotech firm - Insider Louisville". Archived from the original on 2019-08-16. Retrieved 2019-08-16.