PI3K/AKT/mTOR pathway (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "PI3K/AKT/mTOR pathway" in English language version.

refsWebsite

Global rank English rank

56nih.gov

4^th place

38doi.org

2^nd place

15worldcat.org

5^th place

13semanticscholar.org

11^th place

8^th place

4harvard.edu

18^th place

17^th place

1aacrjournals.org

8,869^th place

8,487^th place

1fda.gov

447^th place

338^th place

1ucl.ac.uk

1,306^th place

885^th place

aacrjournals.org

cancerres.aacrjournals.org

Bono, Johann de; Arkenau, Hendrik-Tobias; Mateo, Joaquin; Infante, Jeffrey R.; Burris, Howard A.; Bang, Yung-Jue; Eder, Joseph; Sharma, Sunil; Chung, Hyun C.; Decordova, Shaun; Swales, Karen E. (2015-08-01). "Abstract CT328: Exploratory genetic analysis of tumors from a phase I/II dose escalation study of GSK2636771 in patients (pts) with PTEN deficient advanced tumors". Cancer Research. 75 (15 Supplement): CT328. doi:10.1158/1538-7445.AM2015-CT328. ISSN 0008-5472.

doi.org

King D, Yeomanson D, Bryant HE (May 2015). "PI3King the lock: targeting the PI3K/Akt/mTOR pathway as a novel therapeutic strategy in neuroblastoma". Journal of Pediatric Hematology/Oncology. 37 (4): 245–51. doi:10.1097/MPH.0000000000000329. PMID 25811750. S2CID 42323379.
Peltier J, O'Neill A, Schaffer DV (September 2007). "PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation". Developmental Neurobiology. 67 (10): 1348–61. doi:10.1002/dneu.20506. PMID 17638387. S2CID 16337839.
Rafalski VA, Brunet A (February 2011). "Energy metabolism in adult neural stem cell fate". Progress in Neurobiology. 93 (2): 182–203. doi:10.1016/j.pneurobio.2010.10.007. PMID 21056618. S2CID 16305263.
Man HY, Wang Q, Lu WY, Ju W, Ahmadian G, Liu L, et al. (May 2003). "Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons". Neuron. 38 (4): 611–24. doi:10.1016/s0896-6273(03)00228-9. PMID 12765612. S2CID 17419450.
Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, et al. (2011). "Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF". PLOS ONE. 6 (8): e23414. Bibcode:2011PLoSO...623414O. doi:10.1371/journal.pone.0023414. PMC 3160859. PMID 21887250.
Garcia-Galiano D, Borges BC, Allen SJ, Elias CF (2019). "PI3K signalling in leptin receptor cells: Role in growth and reproduction". Journal of Neuroendocrinology. 31 (5): e12685. doi:10.1111/jne.12685. PMC 6533139. PMID 30618188.
Wyatt LA, Filbin MT, Keirstead HS (August 2014). "PTEN inhibition enhances neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells". The Journal of Comparative Neurology. 522 (12): 2741–55. doi:10.1002/cne.23580. PMID 24610700. S2CID 205683500.
Sui L, Wang J, Li BM (October 2008). "Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex". Learning & Memory. 15 (10): 762–76. doi:10.1101/lm.1067808. PMID 18832563.
Aziz AU, Farid S, Qin K, Wang H, Liu B (February 2018). "PIM Kinases and Their Relevance to the PI3K/AKT/mTOR Pathway in the Regulation of Ovarian Cancer". Biomolecules. 8 (1): 7. doi:10.3390/biom8010007. PMC 5871976. PMID 29401696.
Ciccone, Marcia A.; Maoz, Asaf; Casabar, Jennifer K.; Machida, Hiroko; Mabuchi, Seiji; Matsuo, Koji (July 2016). "Clinical outcome of treatment with serine-threonine kinase inhibitors in recurrent epithelial ovarian cancer: a systematic review of literature". Expert Opinion on Investigational Drugs. 25 (7): 781–796. doi:10.1080/13543784.2016.1181748. ISSN 1744-7658. PMC 7534810. PMID 27101098. S2CID 28717797.
Maoz, Asaf; Ciccone, Marcia A.; Matsuzaki, Shinya; Coleman, Robert L.; Matsuo, Koji (2019-11-22). "Emerging serine-threonine kinase inhibitors for treating ovarian cancer". Expert Opinion on Emerging Drugs. 24 (4): 239–253. doi:10.1080/14728214.2019.1696773. ISSN 1744-7623. PMC 7526049. PMID 31755325. S2CID 208227849.
Raphael J, Desautels D, Pritchard KI, Petkova E, Shah PS (March 2018). "Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis". European Journal of Cancer. 91: 38–46. doi:10.1016/j.ejca.2017.12.010. PMID 29331750.
Costa RL, Han HS, Gradishar WJ (June 2018). "Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review". Breast Cancer Research and Treatment. 169 (3): 397–406. doi:10.1007/s10549-018-4697-y. PMID 29417298. S2CID 19888056.
Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, et al. (October 2008). "NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations". Cancer Research. 68 (19): 8022–30. doi:10.1158/0008-5472.CAN-08-1385. PMID 18829560.
Liu ST, Hui G, Mathis C, Chamie K, Pantuck AJ, Drakaki A (April 2018). "The Current Status and Future Role of the Phosphoinositide 3 Kinase/AKT Signaling Pathway in Urothelial Cancer: An Old Pathway in the New Immunotherapy Era". Clinical Genitourinary Cancer. 16 (2): e269–e276. doi:10.1016/j.clgc.2017.10.011. PMID 29199023. S2CID 4533538.
Winkler DG, Faia KL, DiNitto JP, Ali JA, White KF, Brophy EE, et al. (November 2013). "PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models". Chemistry & Biology. 20 (11): 1364–74. doi:10.1016/j.chembiol.2013.09.017. PMID 24211136.
Park, Soonbum; Kim, Young Sik; Kim, Davis Yeon; So, Insuk; Jeon, Ju-Hong (December 2018). "PI3K pathway in prostate cancer: All resistant roads lead to PI3K". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1870 (2): 198–206. doi:10.1016/j.bbcan.2018.09.001. ISSN 1879-2561. PMID 30300679. S2CID 52947672.
Carver, Brett S.; Chapinski, Caren; Wongvipat, John; Hieronymus, Haley; Chen, Yu; Chandarlapaty, Sarat; Arora, Vivek K.; Le, Carl; Koutcher, Jason; Scher, Howard; Scardino, Peter T. (2011-05-17). "Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer". Cancer Cell. 19 (5): 575–586. doi:10.1016/j.ccr.2011.04.008. ISSN 1878-3686. PMC 3142785. PMID 21575859.
Zahari, Muhammad Saddiq; Wu, Xinyan; Blair, Brian G.; Pinto, Sneha M.; Nirujogi, Raja S.; Jelinek, Christine A.; Malhotra, Radhika; Kim, Min-Sik; Park, Ben Ho; Pandey, Akhilesh (2015-09-04). "Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome". Journal of Proteome Research. 14 (9): 3882–3891. doi:10.1021/acs.jproteome.5b00302. ISSN 1535-3907. PMC 4641567. PMID 26267517.
Pearson, Helen B.; Li, Jason; Meniel, Valerie S.; Fennell, Christina M.; Waring, Paul; Montgomery, Karen G.; Rebello, Richard J.; Macpherson, Arthi A.; Koushyar, Sarah; Furic, Luc; Cullinane, Carleen (June 2018). "Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth". Cancer Discovery. 8 (6): 764–779. doi:10.1158/2159-8290.CD-17-0867. ISSN 2159-8290. PMID 29581176.
Agell, Laia; Hernández, Silvia; Salido, Marta; de Muga, Silvia; Juanpere, Nuria; Arumí-Uria, Montserrat; Menendez, Silvia; Lorenzo, Marta; Lorente, José A.; Serrano, Sergio; Lloreta, Josep (March 2011). "PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events". Modern Pathology. 24 (3): 443–452. doi:10.1038/modpathol.2010.208. ISSN 1530-0285. PMID 21113138. S2CID 27405431.
Simpson, Benjamin S.; Camacho, Niedzica; Luxton, Hayley J.; Pye, Hayley; Finn, Ron; Heavey, Susan; Pitt, Jason; Moore, Caroline M.; Whitaker, Hayley C. (2020-08-14). "Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype". Communications Biology. 3 (1): 440. doi:10.1038/s42003-020-01175-x. ISSN 2399-3642. PMC 7429505. PMID 32796921. S2CID 221118233.
Bono, Johann de; Arkenau, Hendrik-Tobias; Mateo, Joaquin; Infante, Jeffrey R.; Burris, Howard A.; Bang, Yung-Jue; Eder, Joseph; Sharma, Sunil; Chung, Hyun C.; Decordova, Shaun; Swales, Karen E. (2015-08-01). "Abstract CT328: Exploratory genetic analysis of tumors from a phase I/II dose escalation study of GSK2636771 in patients (pts) with PTEN deficient advanced tumors". Cancer Research. 75 (15 Supplement): CT328. doi:10.1158/1538-7445.AM2015-CT328. ISSN 0008-5472.
Huck BR, Mochalkin I (July 2017). "Recent progress towards clinically relevant ATP-competitive Akt inhibitors". Bioorganic & Medicinal Chemistry Letters. 27 (13): 2838–2848. doi:10.1016/j.bmcl.2017.04.090. PMID 28506751.
Chakrabarty A, Sánchez V, Kuba MG, Rinehart C, Arteaga CL (February 2012). "Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors". Proceedings of the National Academy of Sciences of the United States of America. 109 (8): 2718–23. Bibcode:2012PNAS..109.2718C. doi:10.1073/pnas.1018001108. PMC 3286932. PMID 21368164.
Cappellen D, Gil Diez de Medina S, Chopin D, Thiery JP, Radvanyi F (June 1997). "Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder". Oncogene. 14 (25): 3059–66. doi:10.1038/sj.onc.1201154. PMID 9223669.
Heavey, Susan; O'Byrne, Kenneth J.; Gately, Kathy (April 2014). "Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC". Cancer Treatment Reviews. 40 (3): 445–456. doi:10.1016/j.ctrv.2013.08.006. ISSN 1532-1967. PMID 24055012.
Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Young, Vincent; Ryan, Ronan; Nicholson, Siobhan; Leonard, Niamh; McVeigh, Niall; Barr, Martin; O'Byrne, Kenneth; Gately, Kathy (2016-11-29). "In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC". Oncotarget. 7 (48): 79526–79543. doi:10.18632/oncotarget.12755. ISSN 1949-2553. PMC 5346733. PMID 27765909.
Luszczak, Sabina; Kumar, Christopher; Sathyadevan, Vignesh Krishna; Simpson, Benjamin S.; Gately, Kathy A.; Whitaker, Hayley C.; Heavey, Susan (2020). "PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer". Signal Transduction and Targeted Therapy. 5: 7. doi:10.1038/s41392-020-0109-y. ISSN 2059-3635. PMC 6992635. PMID 32025342.
Malone, Tom; Schäfer, Lea; Simon, Nathalie; Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Moore, Gillian; Gately, Kathy (March 2020). "Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer" (PDF). Pharmacology & Therapeutics. 207: 107454. doi:10.1016/j.pharmthera.2019.107454. ISSN 1879-016X. PMID 31836451. S2CID 209357486.
Heavey, Susan; Dowling, Paul; Moore, Gillian; Barr, Martin P.; Kelly, Niamh; Maher, Stephen G.; Cuffe, Sinead; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (26 January 2018). "Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines". Scientific Reports. 8 (1): 1652. Bibcode:2018NatSR...8.1652H. doi:10.1038/s41598-018-19688-1. ISSN 2045-2322. PMC 5786033. PMID 29374181.
Heavey, Susan; Godwin, Peter; Baird, Anne-Marie; Barr, Martin P.; Umezawa, Kazuo; Cuffe, Sinéad; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (October 2014). "Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC". Cancer Biology & Therapy. 15 (10): 1367–1377. doi:10.4161/cbt.29841. ISSN 1555-8576. PMC 4130730. PMID 25025901.
Schmid AC, Byrne RD, Vilar R, Woscholski R (May 2004). "Bisperoxovanadium compounds are potent PTEN inhibitors". FEBS Letters. 566 (1–3): 35–8. doi:10.1016/j.febslet.2004.03.102. PMID 15147864.
Mihai C, Bao S, Lai JP, Ghadiali SN, Knoell DL (February 2012). "PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration". American Journal of Physiology. Lung Cellular and Molecular Physiology. 302 (3): L287-99. doi:10.1152/ajplung.00037.2011. PMC 3289272. PMID 22037358.
Lai JP, Dalton JT, Knoell DL (December 2007). "Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair". British Journal of Pharmacology. 152 (8): 1172–84. doi:10.1038/sj.bjp.0707501. PMC 2189995. PMID 17922022.
Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, Chen J, Xu XM (2012). "Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury". PLOS ONE. 7 (1): e30012. Bibcode:2012PLoSO...730012W. doi:10.1371/journal.pone.0030012. PMC 3254642. PMID 22253859.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, et al. (December 2016). "Novel genetic loci underlying human intracranial volume identified through genome-wide association". Nature Neuroscience. 19 (12): 1569–1582. doi:10.1038/nn.4398. PMC 5227112. PMID 27694991.
Martin NP, Marron Fernandez de Velasco E, Mizuno F, Scappini EL, Gloss B, Erxleben C, et al. (September 2014). "A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo". Endocrinology. 155 (9): 3713–24. doi:10.1210/en.2013-2058. PMC 4138568. PMID 24932806.

fda.gov

"duvelisib (COPIKTRA, Verastem, Inc.) for adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)". U.S. Food and Drug Administration. Retrieved 23 October 2018.

harvard.edu

ui.adsabs.harvard.edu

Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, et al. (2011). "Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF". PLOS ONE. 6 (8): e23414. Bibcode:2011PLoSO...623414O. doi:10.1371/journal.pone.0023414. PMC 3160859. PMID 21887250.
Chakrabarty A, Sánchez V, Kuba MG, Rinehart C, Arteaga CL (February 2012). "Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors". Proceedings of the National Academy of Sciences of the United States of America. 109 (8): 2718–23. Bibcode:2012PNAS..109.2718C. doi:10.1073/pnas.1018001108. PMC 3286932. PMID 21368164.
Heavey, Susan; Dowling, Paul; Moore, Gillian; Barr, Martin P.; Kelly, Niamh; Maher, Stephen G.; Cuffe, Sinead; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (26 January 2018). "Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines". Scientific Reports. 8 (1): 1652. Bibcode:2018NatSR...8.1652H. doi:10.1038/s41598-018-19688-1. ISSN 2045-2322. PMC 5786033. PMID 29374181.
Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, Chen J, Xu XM (2012). "Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury". PLOS ONE. 7 (1): e30012. Bibcode:2012PLoSO...730012W. doi:10.1371/journal.pone.0030012. PMC 3254642. PMID 22253859.

nih.gov

pubmed.ncbi.nlm.nih.gov

King D, Yeomanson D, Bryant HE (May 2015). "PI3King the lock: targeting the PI3K/Akt/mTOR pathway as a novel therapeutic strategy in neuroblastoma". Journal of Pediatric Hematology/Oncology. 37 (4): 245–51. doi:10.1097/MPH.0000000000000329. PMID 25811750. S2CID 42323379.
Peltier J, O'Neill A, Schaffer DV (September 2007). "PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation". Developmental Neurobiology. 67 (10): 1348–61. doi:10.1002/dneu.20506. PMID 17638387. S2CID 16337839.
Rafalski VA, Brunet A (February 2011). "Energy metabolism in adult neural stem cell fate". Progress in Neurobiology. 93 (2): 182–203. doi:10.1016/j.pneurobio.2010.10.007. PMID 21056618. S2CID 16305263.
Man HY, Wang Q, Lu WY, Ju W, Ahmadian G, Liu L, et al. (May 2003). "Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons". Neuron. 38 (4): 611–24. doi:10.1016/s0896-6273(03)00228-9. PMID 12765612. S2CID 17419450.
Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, et al. (2011). "Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF". PLOS ONE. 6 (8): e23414. Bibcode:2011PLoSO...623414O. doi:10.1371/journal.pone.0023414. PMC 3160859. PMID 21887250.
Garcia-Galiano D, Borges BC, Allen SJ, Elias CF (2019). "PI3K signalling in leptin receptor cells: Role in growth and reproduction". Journal of Neuroendocrinology. 31 (5): e12685. doi:10.1111/jne.12685. PMC 6533139. PMID 30618188.
Wyatt LA, Filbin MT, Keirstead HS (August 2014). "PTEN inhibition enhances neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells". The Journal of Comparative Neurology. 522 (12): 2741–55. doi:10.1002/cne.23580. PMID 24610700. S2CID 205683500.
Sui L, Wang J, Li BM (October 2008). "Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex". Learning & Memory. 15 (10): 762–76. doi:10.1101/lm.1067808. PMID 18832563.
Aziz AU, Farid S, Qin K, Wang H, Liu B (February 2018). "PIM Kinases and Their Relevance to the PI3K/AKT/mTOR Pathway in the Regulation of Ovarian Cancer". Biomolecules. 8 (1): 7. doi:10.3390/biom8010007. PMC 5871976. PMID 29401696.
Ciccone, Marcia A.; Maoz, Asaf; Casabar, Jennifer K.; Machida, Hiroko; Mabuchi, Seiji; Matsuo, Koji (July 2016). "Clinical outcome of treatment with serine-threonine kinase inhibitors in recurrent epithelial ovarian cancer: a systematic review of literature". Expert Opinion on Investigational Drugs. 25 (7): 781–796. doi:10.1080/13543784.2016.1181748. ISSN 1744-7658. PMC 7534810. PMID 27101098. S2CID 28717797.
Maoz, Asaf; Ciccone, Marcia A.; Matsuzaki, Shinya; Coleman, Robert L.; Matsuo, Koji (2019-11-22). "Emerging serine-threonine kinase inhibitors for treating ovarian cancer". Expert Opinion on Emerging Drugs. 24 (4): 239–253. doi:10.1080/14728214.2019.1696773. ISSN 1744-7623. PMC 7526049. PMID 31755325. S2CID 208227849.
Raphael J, Desautels D, Pritchard KI, Petkova E, Shah PS (March 2018). "Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis". European Journal of Cancer. 91: 38–46. doi:10.1016/j.ejca.2017.12.010. PMID 29331750.
Costa RL, Han HS, Gradishar WJ (June 2018). "Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review". Breast Cancer Research and Treatment. 169 (3): 397–406. doi:10.1007/s10549-018-4697-y. PMID 29417298. S2CID 19888056.
Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, et al. (October 2008). "NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations". Cancer Research. 68 (19): 8022–30. doi:10.1158/0008-5472.CAN-08-1385. PMID 18829560.
Liu ST, Hui G, Mathis C, Chamie K, Pantuck AJ, Drakaki A (April 2018). "The Current Status and Future Role of the Phosphoinositide 3 Kinase/AKT Signaling Pathway in Urothelial Cancer: An Old Pathway in the New Immunotherapy Era". Clinical Genitourinary Cancer. 16 (2): e269–e276. doi:10.1016/j.clgc.2017.10.011. PMID 29199023. S2CID 4533538.
Winkler DG, Faia KL, DiNitto JP, Ali JA, White KF, Brophy EE, et al. (November 2013). "PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models". Chemistry & Biology. 20 (11): 1364–74. doi:10.1016/j.chembiol.2013.09.017. PMID 24211136.
Park, Soonbum; Kim, Young Sik; Kim, Davis Yeon; So, Insuk; Jeon, Ju-Hong (December 2018). "PI3K pathway in prostate cancer: All resistant roads lead to PI3K". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1870 (2): 198–206. doi:10.1016/j.bbcan.2018.09.001. ISSN 1879-2561. PMID 30300679. S2CID 52947672.
Carver, Brett S.; Chapinski, Caren; Wongvipat, John; Hieronymus, Haley; Chen, Yu; Chandarlapaty, Sarat; Arora, Vivek K.; Le, Carl; Koutcher, Jason; Scher, Howard; Scardino, Peter T. (2011-05-17). "Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer". Cancer Cell. 19 (5): 575–586. doi:10.1016/j.ccr.2011.04.008. ISSN 1878-3686. PMC 3142785. PMID 21575859.
Zahari, Muhammad Saddiq; Wu, Xinyan; Blair, Brian G.; Pinto, Sneha M.; Nirujogi, Raja S.; Jelinek, Christine A.; Malhotra, Radhika; Kim, Min-Sik; Park, Ben Ho; Pandey, Akhilesh (2015-09-04). "Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome". Journal of Proteome Research. 14 (9): 3882–3891. doi:10.1021/acs.jproteome.5b00302. ISSN 1535-3907. PMC 4641567. PMID 26267517.
Pearson, Helen B.; Li, Jason; Meniel, Valerie S.; Fennell, Christina M.; Waring, Paul; Montgomery, Karen G.; Rebello, Richard J.; Macpherson, Arthi A.; Koushyar, Sarah; Furic, Luc; Cullinane, Carleen (June 2018). "Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth". Cancer Discovery. 8 (6): 764–779. doi:10.1158/2159-8290.CD-17-0867. ISSN 2159-8290. PMID 29581176.
Agell, Laia; Hernández, Silvia; Salido, Marta; de Muga, Silvia; Juanpere, Nuria; Arumí-Uria, Montserrat; Menendez, Silvia; Lorenzo, Marta; Lorente, José A.; Serrano, Sergio; Lloreta, Josep (March 2011). "PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events". Modern Pathology. 24 (3): 443–452. doi:10.1038/modpathol.2010.208. ISSN 1530-0285. PMID 21113138. S2CID 27405431.
Simpson, Benjamin S.; Camacho, Niedzica; Luxton, Hayley J.; Pye, Hayley; Finn, Ron; Heavey, Susan; Pitt, Jason; Moore, Caroline M.; Whitaker, Hayley C. (2020-08-14). "Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype". Communications Biology. 3 (1): 440. doi:10.1038/s42003-020-01175-x. ISSN 2399-3642. PMC 7429505. PMID 32796921. S2CID 221118233.
Greenwell IB, Ip A, Cohen JB (November 2017). "PI3K Inhibitors: Understanding Toxicity Mechanisms and Management". Oncology. 31 (11): 821–8. PMID 29179250.
Huck BR, Mochalkin I (July 2017). "Recent progress towards clinically relevant ATP-competitive Akt inhibitors". Bioorganic & Medicinal Chemistry Letters. 27 (13): 2838–2848. doi:10.1016/j.bmcl.2017.04.090. PMID 28506751.
Chakrabarty A, Sánchez V, Kuba MG, Rinehart C, Arteaga CL (February 2012). "Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors". Proceedings of the National Academy of Sciences of the United States of America. 109 (8): 2718–23. Bibcode:2012PNAS..109.2718C. doi:10.1073/pnas.1018001108. PMC 3286932. PMID 21368164.
Cappellen D, Gil Diez de Medina S, Chopin D, Thiery JP, Radvanyi F (June 1997). "Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder". Oncogene. 14 (25): 3059–66. doi:10.1038/sj.onc.1201154. PMID 9223669.
Heavey, Susan; O'Byrne, Kenneth J.; Gately, Kathy (April 2014). "Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC". Cancer Treatment Reviews. 40 (3): 445–456. doi:10.1016/j.ctrv.2013.08.006. ISSN 1532-1967. PMID 24055012.
Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Young, Vincent; Ryan, Ronan; Nicholson, Siobhan; Leonard, Niamh; McVeigh, Niall; Barr, Martin; O'Byrne, Kenneth; Gately, Kathy (2016-11-29). "In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC". Oncotarget. 7 (48): 79526–79543. doi:10.18632/oncotarget.12755. ISSN 1949-2553. PMC 5346733. PMID 27765909.
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Malone, Tom; Schäfer, Lea; Simon, Nathalie; Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Moore, Gillian; Gately, Kathy (March 2020). "Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer" (PDF). Pharmacology & Therapeutics. 207: 107454. doi:10.1016/j.pharmthera.2019.107454. ISSN 1879-016X. PMID 31836451. S2CID 209357486.
Heavey, Susan; Dowling, Paul; Moore, Gillian; Barr, Martin P.; Kelly, Niamh; Maher, Stephen G.; Cuffe, Sinead; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (26 January 2018). "Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines". Scientific Reports. 8 (1): 1652. Bibcode:2018NatSR...8.1652H. doi:10.1038/s41598-018-19688-1. ISSN 2045-2322. PMC 5786033. PMID 29374181.
Heavey, Susan; Godwin, Peter; Baird, Anne-Marie; Barr, Martin P.; Umezawa, Kazuo; Cuffe, Sinéad; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (October 2014). "Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC". Cancer Biology & Therapy. 15 (10): 1367–1377. doi:10.4161/cbt.29841. ISSN 1555-8576. PMC 4130730. PMID 25025901.
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Lai JP, Dalton JT, Knoell DL (December 2007). "Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair". British Journal of Pharmacology. 152 (8): 1172–84. doi:10.1038/sj.bjp.0707501. PMC 2189995. PMID 17922022.
Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, Chen J, Xu XM (2012). "Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury". PLOS ONE. 7 (1): e30012. Bibcode:2012PLoSO...730012W. doi:10.1371/journal.pone.0030012. PMC 3254642. PMID 22253859.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, et al. (December 2016). "Novel genetic loci underlying human intracranial volume identified through genome-wide association". Nature Neuroscience. 19 (12): 1569–1582. doi:10.1038/nn.4398. PMC 5227112. PMID 27694991.
Martin NP, Marron Fernandez de Velasco E, Mizuno F, Scappini EL, Gloss B, Erxleben C, et al. (September 2014). "A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo". Endocrinology. 155 (9): 3713–24. doi:10.1210/en.2013-2058. PMC 4138568. PMID 24932806.

ncbi.nlm.nih.gov

Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, et al. (2011). "Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF". PLOS ONE. 6 (8): e23414. Bibcode:2011PLoSO...623414O. doi:10.1371/journal.pone.0023414. PMC 3160859. PMID 21887250.
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Carver, Brett S.; Chapinski, Caren; Wongvipat, John; Hieronymus, Haley; Chen, Yu; Chandarlapaty, Sarat; Arora, Vivek K.; Le, Carl; Koutcher, Jason; Scher, Howard; Scardino, Peter T. (2011-05-17). "Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer". Cancer Cell. 19 (5): 575–586. doi:10.1016/j.ccr.2011.04.008. ISSN 1878-3686. PMC 3142785. PMID 21575859.
Zahari, Muhammad Saddiq; Wu, Xinyan; Blair, Brian G.; Pinto, Sneha M.; Nirujogi, Raja S.; Jelinek, Christine A.; Malhotra, Radhika; Kim, Min-Sik; Park, Ben Ho; Pandey, Akhilesh (2015-09-04). "Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome". Journal of Proteome Research. 14 (9): 3882–3891. doi:10.1021/acs.jproteome.5b00302. ISSN 1535-3907. PMC 4641567. PMID 26267517.
Simpson, Benjamin S.; Camacho, Niedzica; Luxton, Hayley J.; Pye, Hayley; Finn, Ron; Heavey, Susan; Pitt, Jason; Moore, Caroline M.; Whitaker, Hayley C. (2020-08-14). "Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype". Communications Biology. 3 (1): 440. doi:10.1038/s42003-020-01175-x. ISSN 2399-3642. PMC 7429505. PMID 32796921. S2CID 221118233.
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Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Young, Vincent; Ryan, Ronan; Nicholson, Siobhan; Leonard, Niamh; McVeigh, Niall; Barr, Martin; O'Byrne, Kenneth; Gately, Kathy (2016-11-29). "In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC". Oncotarget. 7 (48): 79526–79543. doi:10.18632/oncotarget.12755. ISSN 1949-2553. PMC 5346733. PMID 27765909.
Luszczak, Sabina; Kumar, Christopher; Sathyadevan, Vignesh Krishna; Simpson, Benjamin S.; Gately, Kathy A.; Whitaker, Hayley C.; Heavey, Susan (2020). "PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer". Signal Transduction and Targeted Therapy. 5: 7. doi:10.1038/s41392-020-0109-y. ISSN 2059-3635. PMC 6992635. PMID 32025342.
Heavey, Susan; Dowling, Paul; Moore, Gillian; Barr, Martin P.; Kelly, Niamh; Maher, Stephen G.; Cuffe, Sinead; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (26 January 2018). "Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines". Scientific Reports. 8 (1): 1652. Bibcode:2018NatSR...8.1652H. doi:10.1038/s41598-018-19688-1. ISSN 2045-2322. PMC 5786033. PMID 29374181.
Heavey, Susan; Godwin, Peter; Baird, Anne-Marie; Barr, Martin P.; Umezawa, Kazuo; Cuffe, Sinéad; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (October 2014). "Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC". Cancer Biology & Therapy. 15 (10): 1367–1377. doi:10.4161/cbt.29841. ISSN 1555-8576. PMC 4130730. PMID 25025901.
Mihai C, Bao S, Lai JP, Ghadiali SN, Knoell DL (February 2012). "PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration". American Journal of Physiology. Lung Cellular and Molecular Physiology. 302 (3): L287-99. doi:10.1152/ajplung.00037.2011. PMC 3289272. PMID 22037358.
Lai JP, Dalton JT, Knoell DL (December 2007). "Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair". British Journal of Pharmacology. 152 (8): 1172–84. doi:10.1038/sj.bjp.0707501. PMC 2189995. PMID 17922022.
Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, Chen J, Xu XM (2012). "Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury". PLOS ONE. 7 (1): e30012. Bibcode:2012PLoSO...730012W. doi:10.1371/journal.pone.0030012. PMC 3254642. PMID 22253859.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, et al. (December 2016). "Novel genetic loci underlying human intracranial volume identified through genome-wide association". Nature Neuroscience. 19 (12): 1569–1582. doi:10.1038/nn.4398. PMC 5227112. PMID 27694991.
Martin NP, Marron Fernandez de Velasco E, Mizuno F, Scappini EL, Gloss B, Erxleben C, et al. (September 2014). "A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo". Endocrinology. 155 (9): 3713–24. doi:10.1210/en.2013-2058. PMC 4138568. PMID 24932806.

semanticscholar.org

api.semanticscholar.org

King D, Yeomanson D, Bryant HE (May 2015). "PI3King the lock: targeting the PI3K/Akt/mTOR pathway as a novel therapeutic strategy in neuroblastoma". Journal of Pediatric Hematology/Oncology. 37 (4): 245–51. doi:10.1097/MPH.0000000000000329. PMID 25811750. S2CID 42323379.
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Maoz, Asaf; Ciccone, Marcia A.; Matsuzaki, Shinya; Coleman, Robert L.; Matsuo, Koji (2019-11-22). "Emerging serine-threonine kinase inhibitors for treating ovarian cancer". Expert Opinion on Emerging Drugs. 24 (4): 239–253. doi:10.1080/14728214.2019.1696773. ISSN 1744-7623. PMC 7526049. PMID 31755325. S2CID 208227849.
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Agell, Laia; Hernández, Silvia; Salido, Marta; de Muga, Silvia; Juanpere, Nuria; Arumí-Uria, Montserrat; Menendez, Silvia; Lorenzo, Marta; Lorente, José A.; Serrano, Sergio; Lloreta, Josep (March 2011). "PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events". Modern Pathology. 24 (3): 443–452. doi:10.1038/modpathol.2010.208. ISSN 1530-0285. PMID 21113138. S2CID 27405431.
Simpson, Benjamin S.; Camacho, Niedzica; Luxton, Hayley J.; Pye, Hayley; Finn, Ron; Heavey, Susan; Pitt, Jason; Moore, Caroline M.; Whitaker, Hayley C. (2020-08-14). "Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype". Communications Biology. 3 (1): 440. doi:10.1038/s42003-020-01175-x. ISSN 2399-3642. PMC 7429505. PMID 32796921. S2CID 221118233.
Malone, Tom; Schäfer, Lea; Simon, Nathalie; Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Moore, Gillian; Gately, Kathy (March 2020). "Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer" (PDF). Pharmacology & Therapeutics. 207: 107454. doi:10.1016/j.pharmthera.2019.107454. ISSN 1879-016X. PMID 31836451. S2CID 209357486.

ucl.ac.uk

discovery.ucl.ac.uk

Malone, Tom; Schäfer, Lea; Simon, Nathalie; Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Moore, Gillian; Gately, Kathy (March 2020). "Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer" (PDF). Pharmacology & Therapeutics. 207: 107454. doi:10.1016/j.pharmthera.2019.107454. ISSN 1879-016X. PMID 31836451. S2CID 209357486.

worldcat.org

Ciccone, Marcia A.; Maoz, Asaf; Casabar, Jennifer K.; Machida, Hiroko; Mabuchi, Seiji; Matsuo, Koji (July 2016). "Clinical outcome of treatment with serine-threonine kinase inhibitors in recurrent epithelial ovarian cancer: a systematic review of literature". Expert Opinion on Investigational Drugs. 25 (7): 781–796. doi:10.1080/13543784.2016.1181748. ISSN 1744-7658. PMC 7534810. PMID 27101098. S2CID 28717797.
Maoz, Asaf; Ciccone, Marcia A.; Matsuzaki, Shinya; Coleman, Robert L.; Matsuo, Koji (2019-11-22). "Emerging serine-threonine kinase inhibitors for treating ovarian cancer". Expert Opinion on Emerging Drugs. 24 (4): 239–253. doi:10.1080/14728214.2019.1696773. ISSN 1744-7623. PMC 7526049. PMID 31755325. S2CID 208227849.
Park, Soonbum; Kim, Young Sik; Kim, Davis Yeon; So, Insuk; Jeon, Ju-Hong (December 2018). "PI3K pathway in prostate cancer: All resistant roads lead to PI3K". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1870 (2): 198–206. doi:10.1016/j.bbcan.2018.09.001. ISSN 1879-2561. PMID 30300679. S2CID 52947672.
Carver, Brett S.; Chapinski, Caren; Wongvipat, John; Hieronymus, Haley; Chen, Yu; Chandarlapaty, Sarat; Arora, Vivek K.; Le, Carl; Koutcher, Jason; Scher, Howard; Scardino, Peter T. (2011-05-17). "Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer". Cancer Cell. 19 (5): 575–586. doi:10.1016/j.ccr.2011.04.008. ISSN 1878-3686. PMC 3142785. PMID 21575859.
Zahari, Muhammad Saddiq; Wu, Xinyan; Blair, Brian G.; Pinto, Sneha M.; Nirujogi, Raja S.; Jelinek, Christine A.; Malhotra, Radhika; Kim, Min-Sik; Park, Ben Ho; Pandey, Akhilesh (2015-09-04). "Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome". Journal of Proteome Research. 14 (9): 3882–3891. doi:10.1021/acs.jproteome.5b00302. ISSN 1535-3907. PMC 4641567. PMID 26267517.
Pearson, Helen B.; Li, Jason; Meniel, Valerie S.; Fennell, Christina M.; Waring, Paul; Montgomery, Karen G.; Rebello, Richard J.; Macpherson, Arthi A.; Koushyar, Sarah; Furic, Luc; Cullinane, Carleen (June 2018). "Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth". Cancer Discovery. 8 (6): 764–779. doi:10.1158/2159-8290.CD-17-0867. ISSN 2159-8290. PMID 29581176.
Agell, Laia; Hernández, Silvia; Salido, Marta; de Muga, Silvia; Juanpere, Nuria; Arumí-Uria, Montserrat; Menendez, Silvia; Lorenzo, Marta; Lorente, José A.; Serrano, Sergio; Lloreta, Josep (March 2011). "PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events". Modern Pathology. 24 (3): 443–452. doi:10.1038/modpathol.2010.208. ISSN 1530-0285. PMID 21113138. S2CID 27405431.
Simpson, Benjamin S.; Camacho, Niedzica; Luxton, Hayley J.; Pye, Hayley; Finn, Ron; Heavey, Susan; Pitt, Jason; Moore, Caroline M.; Whitaker, Hayley C. (2020-08-14). "Genetic alterations in the 3q26.31-32 locus confer an aggressive prostate cancer phenotype". Communications Biology. 3 (1): 440. doi:10.1038/s42003-020-01175-x. ISSN 2399-3642. PMC 7429505. PMID 32796921. S2CID 221118233.
Bono, Johann de; Arkenau, Hendrik-Tobias; Mateo, Joaquin; Infante, Jeffrey R.; Burris, Howard A.; Bang, Yung-Jue; Eder, Joseph; Sharma, Sunil; Chung, Hyun C.; Decordova, Shaun; Swales, Karen E. (2015-08-01). "Abstract CT328: Exploratory genetic analysis of tumors from a phase I/II dose escalation study of GSK2636771 in patients (pts) with PTEN deficient advanced tumors". Cancer Research. 75 (15 Supplement): CT328. doi:10.1158/1538-7445.AM2015-CT328. ISSN 0008-5472.
Heavey, Susan; O'Byrne, Kenneth J.; Gately, Kathy (April 2014). "Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC". Cancer Treatment Reviews. 40 (3): 445–456. doi:10.1016/j.ctrv.2013.08.006. ISSN 1532-1967. PMID 24055012.
Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Young, Vincent; Ryan, Ronan; Nicholson, Siobhan; Leonard, Niamh; McVeigh, Niall; Barr, Martin; O'Byrne, Kenneth; Gately, Kathy (2016-11-29). "In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC". Oncotarget. 7 (48): 79526–79543. doi:10.18632/oncotarget.12755. ISSN 1949-2553. PMC 5346733. PMID 27765909.
Luszczak, Sabina; Kumar, Christopher; Sathyadevan, Vignesh Krishna; Simpson, Benjamin S.; Gately, Kathy A.; Whitaker, Hayley C.; Heavey, Susan (2020). "PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer". Signal Transduction and Targeted Therapy. 5: 7. doi:10.1038/s41392-020-0109-y. ISSN 2059-3635. PMC 6992635. PMID 32025342.
Malone, Tom; Schäfer, Lea; Simon, Nathalie; Heavey, Susan; Cuffe, Sinead; Finn, Stephen; Moore, Gillian; Gately, Kathy (March 2020). "Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer" (PDF). Pharmacology & Therapeutics. 207: 107454. doi:10.1016/j.pharmthera.2019.107454. ISSN 1879-016X. PMID 31836451. S2CID 209357486.
Heavey, Susan; Dowling, Paul; Moore, Gillian; Barr, Martin P.; Kelly, Niamh; Maher, Stephen G.; Cuffe, Sinead; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (26 January 2018). "Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines". Scientific Reports. 8 (1): 1652. Bibcode:2018NatSR...8.1652H. doi:10.1038/s41598-018-19688-1. ISSN 2045-2322. PMC 5786033. PMID 29374181.
Heavey, Susan; Godwin, Peter; Baird, Anne-Marie; Barr, Martin P.; Umezawa, Kazuo; Cuffe, Sinéad; Finn, Stephen P.; O'Byrne, Kenneth J.; Gately, Kathy (October 2014). "Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC". Cancer Biology & Therapy. 15 (10): 1367–1377. doi:10.4161/cbt.29841. ISSN 1555-8576. PMC 4130730. PMID 25025901.