Analysis of information sources in references of the Wikipedia article "Pattern hair loss" in English language version.
The European AGA risk alleles, however, are fixed in the East Asian sample (including 57K) and their frequencies therefore do not correlate with the AGA frequencies. As AGA might be regarded as a secondary sexual characteristic, rather than a disorder, it is possible that the hair loss itself was under enhanced sexual selection by identifying the older male leader comparable to the silver-backed gorilla (Randall 2007). The reported lower prevalence of AGA in Africans might then be explained by the importance of scalp hair for the protection against the tropical sun which outweighed the enhanced sexual selection (Randall 2007). Since the causative variant has not yet been identified, the lower prevalence of AGA in Asia and presumably in Africa might indicate a higher frequency of the functional AGA allele in the European population, either due to its origin on a Europe-specific background or differences in population demography. Alleles of 21 SNPs between AR and EDA2R are more frequent in Europeans than in East Asians and Africans (Supplementary Table 1).
Male pattern baldness is androgen dependent, since it does not occur in castrates, unless they are given testosterone (Hamilton 1942), nor in XY individuals with androgen insensitivity due to non-functional androgen receptors (see Chapter 3). The genetic involvement in androgenetic alopecia is also pronounced.
{{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link){{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link){{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)The European AGA risk alleles, however, are fixed in the East Asian sample (including 57K) and their frequencies therefore do not correlate with the AGA frequencies. As AGA might be regarded as a secondary sexual characteristic, rather than a disorder, it is possible that the hair loss itself was under enhanced sexual selection by identifying the older male leader comparable to the silver-backed gorilla (Randall 2007). The reported lower prevalence of AGA in Africans might then be explained by the importance of scalp hair for the protection against the tropical sun which outweighed the enhanced sexual selection (Randall 2007). Since the causative variant has not yet been identified, the lower prevalence of AGA in Asia and presumably in Africa might indicate a higher frequency of the functional AGA allele in the European population, either due to its origin on a Europe-specific background or differences in population demography. Alleles of 21 SNPs between AR and EDA2R are more frequent in Europeans than in East Asians and Africans (Supplementary Table 1).
{{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link){{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link){{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)The European AGA risk alleles, however, are fixed in the East Asian sample (including 57K) and their frequencies therefore do not correlate with the AGA frequencies. As AGA might be regarded as a secondary sexual characteristic, rather than a disorder, it is possible that the hair loss itself was under enhanced sexual selection by identifying the older male leader comparable to the silver-backed gorilla (Randall 2007). The reported lower prevalence of AGA in Africans might then be explained by the importance of scalp hair for the protection against the tropical sun which outweighed the enhanced sexual selection (Randall 2007). Since the causative variant has not yet been identified, the lower prevalence of AGA in Asia and presumably in Africa might indicate a higher frequency of the functional AGA allele in the European population, either due to its origin on a Europe-specific background or differences in population demography. Alleles of 21 SNPs between AR and EDA2R are more frequent in Europeans than in East Asians and Africans (Supplementary Table 1).
{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link){{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link)The European AGA risk alleles, however, are fixed in the East Asian sample (including 57K) and their frequencies therefore do not correlate with the AGA frequencies. As AGA might be regarded as a secondary sexual characteristic, rather than a disorder, it is possible that the hair loss itself was under enhanced sexual selection by identifying the older male leader comparable to the silver-backed gorilla (Randall 2007). The reported lower prevalence of AGA in Africans might then be explained by the importance of scalp hair for the protection against the tropical sun which outweighed the enhanced sexual selection (Randall 2007). Since the causative variant has not yet been identified, the lower prevalence of AGA in Asia and presumably in Africa might indicate a higher frequency of the functional AGA allele in the European population, either due to its origin on a Europe-specific background or differences in population demography. Alleles of 21 SNPs between AR and EDA2R are more frequent in Europeans than in East Asians and Africans (Supplementary Table 1).