Analysis of information sources in references of the Wikipedia article "PiHKAL" in English language version.
Last modified:
Prior to its use being criminalised, mescaline (4) also played a significant role in the development of the synthetic phenethylamines by inspiring the investigations of medicinal chemist Alexander Shulgin. Shulgin synthesised at least 179 phenethylamines, which he then tested either alone on himself or along with his wife and close friends, referred to as the 'research group'.[85 ] This work established some structure–psychoactivity relationships for phenethylamines in humans and resulted in the discovery of a number of substituted phenethylamines that remain important, such as the 'classic hallucinogens' DOM (2,5-dimethoxy-4-methylamphetamine; 40) and 2C-B (2,5-dimethoxy-4-bromophenethylamine; 44, Fig. 10), and entactogens MDEA (3,4-methylenedioxy-N-ethylamphetamine; 38) and MBDB (N-methyl-1-(benzodioxol-5-yl)butan-2-amine; 36, Fig. 9). Alexander (Sasha) and Ann Shulgin's book Phenethylamines I have known and loved (PiHKAL)[85] is a seminal work that contains frank and detailed descriptions of the subjective effects of phenethylamines and remains extremely valuable to current phenethylamine research.
Prior to its use being criminalised, mescaline (4) also played a significant role in the development of the synthetic phenethylamines by inspiring the investigations of medicinal chemist Alexander Shulgin. Shulgin synthesised at least 179 phenethylamines, which he then tested either alone on himself or along with his wife and close friends, referred to as the 'research group'.[85 ] This work established some structure–psychoactivity relationships for phenethylamines in humans and resulted in the discovery of a number of substituted phenethylamines that remain important, such as the 'classic hallucinogens' DOM (2,5-dimethoxy-4-methylamphetamine; 40) and 2C-B (2,5-dimethoxy-4-bromophenethylamine; 44, Fig. 10), and entactogens MDEA (3,4-methylenedioxy-N-ethylamphetamine; 38) and MBDB (N-methyl-1-(benzodioxol-5-yl)butan-2-amine; 36, Fig. 9). Alexander (Sasha) and Ann Shulgin's book Phenethylamines I have known and loved (PiHKAL)[85] is a seminal work that contains frank and detailed descriptions of the subjective effects of phenethylamines and remains extremely valuable to current phenethylamine research.
More ambitious explorations of subjective effects elicited by a series of new psychoactive substances developed by Shulgin were conducted by his close associate and psychologist, Myron Stolaroff. Following SEs with LSD in the mid-1950s, Stolaroff became involved in scientific research on psychedelics. After the control of most psychedelic drugs in the 1970s, Stolaroff conducted SEs with newly synthesized psychedelics 2C-B, 2C-E, 2C-T-2, 2C-T-7, 2C-T4, 2C-T-21, and MEM but also MDMA. Besides Shulgin, Stolaroff was the first who systematically explored the psychological states and their possible uses but under noncontrolled conditions (Stolaroff 1994). He understood his research as an attempt "to make the unconscious conscious" and to give some "guidelines for the proper and safe use of psychedelic drugs in therapy and for spiritual growth" (Stolaroff 1994, pp. 13–14).
More ambitious explorations of subjective effects elicited by a series of new psychoactive substances developed by Shulgin were conducted by his close associate and psychologist, Myron Stolaroff. Following SEs with LSD in the mid-1950s, Stolaroff became involved in scientific research on psychedelics. After the control of most psychedelic drugs in the 1970s, Stolaroff conducted SEs with newly synthesized psychedelics 2C-B, 2C-E, 2C-T-2, 2C-T-7, 2C-T4, 2C-T-21, and MEM but also MDMA. Besides Shulgin, Stolaroff was the first who systematically explored the psychological states and their possible uses but under noncontrolled conditions (Stolaroff 1994). He understood his research as an attempt "to make the unconscious conscious" and to give some "guidelines for the proper and safe use of psychedelic drugs in therapy and for spiritual growth" (Stolaroff 1994, pp. 13–14).
{{cite AV media}}: CS1 maint: bot: original URL status unknown (link){{cite book}}: CS1 maint: bot: original URL status unknown (link)Prior to its use being criminalised, mescaline (4) also played a significant role in the development of the synthetic phenethylamines by inspiring the investigations of medicinal chemist Alexander Shulgin. Shulgin synthesised at least 179 phenethylamines, which he then tested either alone on himself or along with his wife and close friends, referred to as the 'research group'.[85 ] This work established some structure–psychoactivity relationships for phenethylamines in humans and resulted in the discovery of a number of substituted phenethylamines that remain important, such as the 'classic hallucinogens' DOM (2,5-dimethoxy-4-methylamphetamine; 40) and 2C-B (2,5-dimethoxy-4-bromophenethylamine; 44, Fig. 10), and entactogens MDEA (3,4-methylenedioxy-N-ethylamphetamine; 38) and MBDB (N-methyl-1-(benzodioxol-5-yl)butan-2-amine; 36, Fig. 9). Alexander (Sasha) and Ann Shulgin's book Phenethylamines I have known and loved (PiHKAL)[85] is a seminal work that contains frank and detailed descriptions of the subjective effects of phenethylamines and remains extremely valuable to current phenethylamine research.
{{cite book}}: CS1 maint: bot: original URL status unknown (link)