Pirfenidone (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Pirfenidone" in English language version.

refsWebsite

Global rank English rank

39nih.gov

4^th place

30doi.org

2^nd place

20web.archive.org

1^st place

3fda.gov

447^th place

338^th place

2guildlink.com.au

low place

2europa.eu

68^th place

117^th place

2semanticscholar.org

11^th place

8^th place

1tga.gov.au

3,984^th place

2,622^nd place

1canada.ca

1,712^th place

1,063^rd place

1medicines.org.uk

3,823^rd place

2,387^th place

1gene.com

low place

1kitoscell.com

low place

1chestnet.org

low place

1patentdocs.org

low place

1swissinfo.ch

1,485^th place

1,650^th place

1harvard.edu

18^th place

17^th place

1worldcat.org

5^th place

1intermune.com

low place

1medpagetoday.com

9,274^th place

5,856^th place

1clinicaltrials.gov

5,225^th place

4,062^nd place

1evaluatepharma.com

low place

1xj-storage.jp

low place

canada.ca

health-products.canada.ca

"Esbriet Product information". Health Canada. 25 April 2012. Archived from the original on 8 January 2023. Retrieved 8 January 2023.

chestnet.org

journal.publications.chestnet.org

Phillips R, Wang T, Blatt LM, Seiwert S (2005). "Pirfenidone mediates differential effects on lipopolysaccharide-induced cytokine expression in human peripheral mononuclear cells". Chest. 128 (4): 169S. doi:10.1378/chest.128.4_meetingabstracts.169s-a. Archived from the original on 3 March 2016. Retrieved 16 March 2013.

clinicaltrials.gov

"Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF)". Nct01366209. U.S. National Institutes of Health: ClinicalTrials.gov. 8 March 2017. Archived from the original on 30 January 2016. Retrieved 9 March 2012.

doi.org

Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Di Sario A, Bendia E, Svegliati Baroni G, Ridolfi F, Casini A, Ceni E, et al. (November 2002). "Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production". Journal of Hepatology. 37 (5): 584–591. doi:10.1016/S0168-8278(02)00245-3. PMID 12399223.
Lin X, Yu M, Wu K, Yuan H, Zhong H (August 2009). "Effects of pirfenidone on proliferation, migration, and collagen contraction of human Tenon's fibroblasts in vitro". Investigative Ophthalmology & Visual Science. 50 (8): 3763–3770. doi:10.1167/iovs.08-2815. PMID 19264889.
Lee BS, Margolin SB, Nowak RA (January 1998). "Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production". The Journal of Clinical Endocrinology and Metabolism. 83 (1): 219–223. doi:10.1210/jcem.83.1.4503. PMID 9435445.
Ozes ON, Blatt LM (2006). "Development of a high throughput collagen assay using a cellular model of idiopathic pulmonary fibrosis". Chest. 130 (4): 230S. doi:10.1378/chest.130.4_meetingabstracts.230s-a.
Nakayama S, Mukae H, Sakamoto N, Kakugawa T, Yoshioka S, Soda H, et al. (January 2008). "Pirfenidone inhibits the expression of HSP47 in TGF-beta1-stimulated human lung fibroblasts". Life Sciences. 82 (3–4): 210–217. doi:10.1016/j.lfs.2007.11.003. PMID 18093617.
Phillips R, Wang T, Blatt LM, Seiwert S (2005). "Pirfenidone mediates differential effects on lipopolysaccharide-induced cytokine expression in human peripheral mononuclear cells". Chest. 128 (4): 169S. doi:10.1378/chest.128.4_meetingabstracts.169s-a. Archived from the original on 3 March 2016. Retrieved 16 March 2013.
Grattendick KJ, Nakashima JM, Feng L, Giri SN, Margolin SB (May 2008). "Effects of three anti-TNF-alpha drugs: etanercept, infliximab and pirfenidone on release of TNF-alpha in medium and TNF-alpha associated with the cell in vitro". International Immunopharmacology. 8 (5): 679–687. doi:10.1016/j.intimp.2008.01.013. PMID 18387510.
Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Kakugawa T, Mukae H, Hayashi T, Ishii H, Abe K, Fujii T, et al. (July 2004). "Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis". European Respiratory Journal. 24 (1): 57–65. doi:10.1183/09031936.04.00120803. PMID 15293605.
Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, et al. (August 2008). "Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis". European Journal of Pharmacology. 590 (1–3): 400–8. doi:10.1016/j.ejphar.2008.06.046. PMID 18598692.
Card JW, Racz WJ, Brien JF, Margolin SB, Massey TE (September 2003). "Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity". Toxicological Sciences. 75 (1): 169–80. doi:10.1093/toxsci/kfg167. PMID 12832656.
Liu H, Drew P, Gaugler AC, Cheng Y, Visner GA (June 2005). "Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway". Am. J. Transplant. 5 (6): 1256–63. doi:10.1111/j.1600-6143.2005.00876.x. PMID 15888029. S2CID 24236706.
Hirano A, Kanehiro A, Ono K, Ito W, Yoshida A, Okada C, et al. (September 2006). "Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge". American Journal of Respiratory Cell and Molecular Biology. 35 (3): 366–77. doi:10.1165/rcmb.2005-0452OC. PMC 2643289. PMID 16675785.
Iyer SN, Margolin SB, Hyde DM, Giri SN (1998). "Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin-hamster model". Experimental Lung Research. 24 (1): 119–32. doi:10.3109/01902149809046058. PMID 9457473.
Lee KW, Everett TH, Rahmutula D, Guerra JM, Wilson E, Ding C, et al. (October 2006). "Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure". Circulation. 114 (16): 1703–12. doi:10.1161/CIRCULATIONAHA.106.624320. PMC 2129103. PMID 17030685.
Nguyen DT, Ding C, Wilson E, Marcus GM, Olgin JE (October 2010). "Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias". Heart Rhythm. 7 (10): 1438–45. doi:10.1016/j.hrthm.2010.04.030. PMID 20433946.
Mirkovic S, Seymour AM, Fenning A, Strachan A, Margolin SB, Taylor SM, et al. (February 2002). "Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats". British Journal of Pharmacology. 135 (4): 961–8. doi:10.1038/sj.bjp.0704539. PMC 1573203. PMID 11861324.
Shimizu T, Kuroda T, Hata S, Fukagawa M, Margolin SB, Kurokawa K (July 1998). "Pirfenidone improves renal function and fibrosis in the post-obstructed kidney". Kidney International. 54 (1): 99–109. doi:10.1046/j.1523-1755.1998.00962.x. PMID 9648068.
Takakuta K, Fujimori A, Chikanishi T, Tanokura A, Iwatsuki Y, Yamamoto M, et al. (March 2010). "Renoprotective properties of pirfenidone in subtotally nephrectomized rats". European Journal of Pharmacology. 629 (1–3): 118–24. doi:10.1016/j.ejphar.2009.12.011. PMID 20006961.
Salazar-Montes A, Ruiz-Corro L, López-Reyes A, Castrejón-Gómez E, Armendáriz-Borunda J (October 2008). "Potent antioxidant role of pirfenidone in experimental cirrhosis". European Journal of Pharmacology. 595 (1–3): 69–77. doi:10.1016/j.ejphar.2008.06.110. PMID 18652820.
García L, Hernández I, Sandoval A, Salazar A, Garcia J, Vera J, et al. (December 2002). "Pirfenidone effectively reverses experimental liver fibrosis". Journal of Hepatology. 37 (6): 797–805. doi:10.1016/S0168-8278(02)00272-6. PMID 12445421.
Zhou C, Liu F, Gallo PH, Baratz ME, Kathju S, Satish L (November 2016). "Anti-fibrotic action of pirfenidone in Dupuytren's disease-derived fibroblasts". BMC Musculoskeletal Disorders. 17 (1): 469. doi:10.1186/s12891-016-1326-y. PMC 5106805. PMID 27835939.
Manjusha P, Prasana JC, Muthu S, Raajaraman BR (5 March 2020). "Density functional studies and spectroscopic analysis (FT-IR, FT-Raman, UV–visible, and NMR)with molecular docking approach on an antifibrotic drug Pirfenidone". Journal of Molecular Structure. 1203: 127394. Bibcode:2020JMoSt120327394M. doi:10.1016/j.molstruc.2019.127394. ISSN 0022-2860.
Stougaard J, Lomholt S, Ommen P, Kelsen J, Kragstrup TW (2018). "The antifibrotic drug pirfenidone inhibits spondyloarthritis fibroblast-like synoviocytes and osteoblasts in vitro". BMC Rheumatology. 2: 33. doi:10.1186/s41927-018-0040-9. PMC 6390625. PMID 30886983.
Taniguchi H, Ebina M, Kondoh Y, et al. (April 2010). "Pirfenidone in idiopathic pulmonary fibrosis". European Respiratory Journal. 35 (4): 821–9. doi:10.1183/09031936.00005209. PMID 19996196.
Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, et al. (May 2011). "Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials". Lancet. 377 (9779): 1760–9. doi:10.1016/S0140-6736(11)60405-4. PMID 21571362. S2CID 10119356.
Spagnolo P, Del Giovane C, Luppi F, Cerri S, Balduzzi S, Walters EH, et al. (2010). "Non-steroid agents for idiopathic pulmonary fibrosis". Cochrane Database of Systematic Reviews (9): CD003134. doi:10.1002/14651858.CD003134.pub2. PMID 20824834.
Macías-Barragán J, Sandoval-Rodríguez A, Navarro-Partida J, Armendáriz-Borunda J (September 2010). "The multifaceted role of pirfenidone and its novel targets". Fibrogenesis & Tissue Repair. 3: 16. doi:10.1186/1755-1536-3-16. PMC 2944211. PMID 20809935.
García L, Hernández I, Sandoval A, Salazar A, Garcia J, Vera J, et al. (December 2002). "Pirfenidone effectively reverses experimental liver fibrosis". Journal of Hepatology. 37 (6): 797–805. doi:10.1016/s0168-8278(02)00272-6. PMID 12445421.

europa.eu

ema.europa.eu

"Esbriet EPAR". European Medicines Agency. 17 September 2018. Archived from the original on 24 November 2020. Retrieved 19 June 2020.
"Esbriet 267 mg hard capsules" (PDF). Summary of product characteristics. European Medicines Agency. Archived (PDF) from the original on 18 March 2018. Retrieved 9 March 2012.

evaluatepharma.com

"China SFDA Approves F647/pirfenidone for the Treatment of Idiopathic Pulmonary Fibrosis". Press Release. EvaluatePharma. 22 September 2011. Archived from the original on 14 December 2019. Retrieved 9 March 2012.

fda.gov

accessdata.fda.gov

"Drug Approval Package: Esbriet (pirfenidone) Capsules NDA #022535". U.S. Food and Drug Administration. 24 December 1999. Archived from the original on 3 January 2021. Retrieved 19 June 2020.
"Esbriet (pirfenidone) Film-coated Tablets". U.S. Food and Drug Administration. 21 February 2018. Archived from the original on 22 May 2020. Retrieved 19 June 2020.

fda.gov

"2022 First Generic Drug Approvals". U.S. Food and Drug Administration (FDA). 3 March 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.

gene.com

"InterMune: Pirfenidone". InterMune. Archived from the original on 21 October 2020. Retrieved 17 December 2015.

guildlink.com.au

"Esbriet® (pirfenidone) Film coated tablets". Roche Products Pty Limited. medsinfo.com.au. Archived from the original on 8 January 2023. Retrieved 8 January 2023.
"Esbriet® (pirfenidone) Capsules". Roche Products Pty Limited. medsinfo.com.au. Archived from the original on 8 January 2023. Retrieved 8 January 2023.

harvard.edu

ui.adsabs.harvard.edu

Manjusha P, Prasana JC, Muthu S, Raajaraman BR (5 March 2020). "Density functional studies and spectroscopic analysis (FT-IR, FT-Raman, UV–visible, and NMR)with molecular docking approach on an antifibrotic drug Pirfenidone". Journal of Molecular Structure. 1203: 127394. Bibcode:2020JMoSt120327394M. doi:10.1016/j.molstruc.2019.127394. ISSN 0022-2860.

intermune.com

"Genentech: Esbriet® (pirfenidone) - Information for Patients". Archived from the original on 13 February 2014.

kitoscell.com

".::KitosCell Gel, Primer Biomodulador::". www.kitoscell.com. Archived from the original on 2 May 2021. Retrieved 18 June 2014.

medicines.org.uk

"Esbriet 267 mg hard capsules". electronic Medicines Compendium. Intermune UK & I Ltd. 3 January 2014. Archived from the original on 12 October 2013. Retrieved 6 March 2014.

medpagetoday.com

Frieden J (10 May 2010). "FDA Nixes Pirfenidone for Now, Wants New Trial". MedPage Today. Archived from the original on 17 January 2021. Retrieved 9 March 2012.

nih.gov

pubmed.ncbi.nlm.nih.gov

Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Di Sario A, Bendia E, Svegliati Baroni G, Ridolfi F, Casini A, Ceni E, et al. (November 2002). "Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production". Journal of Hepatology. 37 (5): 584–591. doi:10.1016/S0168-8278(02)00245-3. PMID 12399223.
Hewitson TD, Kelynack KJ, Tait MG, Martic M, Jones CL, Margolin SB, et al. (2001). "Pirfenidone reduces in vitro rat renal fibroblast activation and mitogenesis". Journal of Nephrology. 14 (6): 453–460. PMID 11783601.
Lin X, Yu M, Wu K, Yuan H, Zhong H (August 2009). "Effects of pirfenidone on proliferation, migration, and collagen contraction of human Tenon's fibroblasts in vitro". Investigative Ophthalmology & Visual Science. 50 (8): 3763–3770. doi:10.1167/iovs.08-2815. PMID 19264889.
Lee BS, Margolin SB, Nowak RA (January 1998). "Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production". The Journal of Clinical Endocrinology and Metabolism. 83 (1): 219–223. doi:10.1210/jcem.83.1.4503. PMID 9435445.
Nakayama S, Mukae H, Sakamoto N, Kakugawa T, Yoshioka S, Soda H, et al. (January 2008). "Pirfenidone inhibits the expression of HSP47 in TGF-beta1-stimulated human lung fibroblasts". Life Sciences. 82 (3–4): 210–217. doi:10.1016/j.lfs.2007.11.003. PMID 18093617.
Grattendick KJ, Nakashima JM, Feng L, Giri SN, Margolin SB (May 2008). "Effects of three anti-TNF-alpha drugs: etanercept, infliximab and pirfenidone on release of TNF-alpha in medium and TNF-alpha associated with the cell in vitro". International Immunopharmacology. 8 (5): 679–687. doi:10.1016/j.intimp.2008.01.013. PMID 18387510.
Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Kakugawa T, Mukae H, Hayashi T, Ishii H, Abe K, Fujii T, et al. (July 2004). "Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis". European Respiratory Journal. 24 (1): 57–65. doi:10.1183/09031936.04.00120803. PMID 15293605.
Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, et al. (August 2008). "Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis". European Journal of Pharmacology. 590 (1–3): 400–8. doi:10.1016/j.ejphar.2008.06.046. PMID 18598692.
Card JW, Racz WJ, Brien JF, Margolin SB, Massey TE (September 2003). "Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity". Toxicological Sciences. 75 (1): 169–80. doi:10.1093/toxsci/kfg167. PMID 12832656.
Liu H, Drew P, Gaugler AC, Cheng Y, Visner GA (June 2005). "Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway". Am. J. Transplant. 5 (6): 1256–63. doi:10.1111/j.1600-6143.2005.00876.x. PMID 15888029. S2CID 24236706.
Hirano A, Kanehiro A, Ono K, Ito W, Yoshida A, Okada C, et al. (September 2006). "Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge". American Journal of Respiratory Cell and Molecular Biology. 35 (3): 366–77. doi:10.1165/rcmb.2005-0452OC. PMC 2643289. PMID 16675785.
Iyer SN, Wild JS, Schiedt MJ, Hyde DM, Margolin SB, Giri SN (June 1995). "Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters". Journal of Laboratory and Clinical Medicine. 125 (6): 779–85. PMID 7539478.
Iyer SN, Margolin SB, Hyde DM, Giri SN (1998). "Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin-hamster model". Experimental Lung Research. 24 (1): 119–32. doi:10.3109/01902149809046058. PMID 9457473.
Iyer SN, Gurujeyalakshmi G, Giri SN (April 1999). "Effects of pirfenidone on procollagen gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis". Journal of Pharmacology and Experimental Therapeutics. 289 (1): 211–8. PMID 10087006.
Lee KW, Everett TH, Rahmutula D, Guerra JM, Wilson E, Ding C, et al. (October 2006). "Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure". Circulation. 114 (16): 1703–12. doi:10.1161/CIRCULATIONAHA.106.624320. PMC 2129103. PMID 17030685.
Nguyen DT, Ding C, Wilson E, Marcus GM, Olgin JE (October 2010). "Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias". Heart Rhythm. 7 (10): 1438–45. doi:10.1016/j.hrthm.2010.04.030. PMID 20433946.
Mirkovic S, Seymour AM, Fenning A, Strachan A, Margolin SB, Taylor SM, et al. (February 2002). "Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats". British Journal of Pharmacology. 135 (4): 961–8. doi:10.1038/sj.bjp.0704539. PMC 1573203. PMID 11861324.
Shimizu T, Kuroda T, Hata S, Fukagawa M, Margolin SB, Kurokawa K (July 1998). "Pirfenidone improves renal function and fibrosis in the post-obstructed kidney". Kidney International. 54 (1): 99–109. doi:10.1046/j.1523-1755.1998.00962.x. PMID 9648068.
Takakuta K, Fujimori A, Chikanishi T, Tanokura A, Iwatsuki Y, Yamamoto M, et al. (March 2010). "Renoprotective properties of pirfenidone in subtotally nephrectomized rats". European Journal of Pharmacology. 629 (1–3): 118–24. doi:10.1016/j.ejphar.2009.12.011. PMID 20006961.
Salazar-Montes A, Ruiz-Corro L, López-Reyes A, Castrejón-Gómez E, Armendáriz-Borunda J (October 2008). "Potent antioxidant role of pirfenidone in experimental cirrhosis". European Journal of Pharmacology. 595 (1–3): 69–77. doi:10.1016/j.ejphar.2008.06.110. PMID 18652820.
García L, Hernández I, Sandoval A, Salazar A, Garcia J, Vera J, et al. (December 2002). "Pirfenidone effectively reverses experimental liver fibrosis". Journal of Hepatology. 37 (6): 797–805. doi:10.1016/S0168-8278(02)00272-6. PMID 12445421.
Zhou C, Liu F, Gallo PH, Baratz ME, Kathju S, Satish L (November 2016). "Anti-fibrotic action of pirfenidone in Dupuytren's disease-derived fibroblasts". BMC Musculoskeletal Disorders. 17 (1): 469. doi:10.1186/s12891-016-1326-y. PMC 5106805. PMID 27835939.
Stougaard J, Lomholt S, Ommen P, Kelsen J, Kragstrup TW (2018). "The antifibrotic drug pirfenidone inhibits spondyloarthritis fibroblast-like synoviocytes and osteoblasts in vitro". BMC Rheumatology. 2: 33. doi:10.1186/s41927-018-0040-9. PMC 6390625. PMID 30886983.
Taniguchi H, Ebina M, Kondoh Y, et al. (April 2010). "Pirfenidone in idiopathic pulmonary fibrosis". European Respiratory Journal. 35 (4): 821–9. doi:10.1183/09031936.00005209. PMID 19996196.
Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, et al. (May 2011). "Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials". Lancet. 377 (9779): 1760–9. doi:10.1016/S0140-6736(11)60405-4. PMID 21571362. S2CID 10119356.
Spagnolo P, Del Giovane C, Luppi F, Cerri S, Balduzzi S, Walters EH, et al. (2010). "Non-steroid agents for idiopathic pulmonary fibrosis". Cochrane Database of Systematic Reviews (9): CD003134. doi:10.1002/14651858.CD003134.pub2. PMID 20824834.
Macías-Barragán J, Sandoval-Rodríguez A, Navarro-Partida J, Armendáriz-Borunda J (September 2010). "The multifaceted role of pirfenidone and its novel targets". Fibrogenesis & Tissue Repair. 3: 16. doi:10.1186/1755-1536-3-16. PMC 2944211. PMID 20809935.
García L, Hernández I, Sandoval A, Salazar A, Garcia J, Vera J, et al. (December 2002). "Pirfenidone effectively reverses experimental liver fibrosis". Journal of Hepatology. 37 (6): 797–805. doi:10.1016/s0168-8278(02)00272-6. PMID 12445421.

ncbi.nlm.nih.gov

Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Schaefer CJ, Ruhrmund DW, Pan L, Seiwert SD, Kossen K (June 2011). "Antifibrotic activities of pirfenidone in animal models". European Respiratory Review. 20 (120): 85–97. doi:10.1183/09059180.00001111. PMC 9487788. PMID 21632796.
Hirano A, Kanehiro A, Ono K, Ito W, Yoshida A, Okada C, et al. (September 2006). "Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge". American Journal of Respiratory Cell and Molecular Biology. 35 (3): 366–77. doi:10.1165/rcmb.2005-0452OC. PMC 2643289. PMID 16675785.
Lee KW, Everett TH, Rahmutula D, Guerra JM, Wilson E, Ding C, et al. (October 2006). "Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure". Circulation. 114 (16): 1703–12. doi:10.1161/CIRCULATIONAHA.106.624320. PMC 2129103. PMID 17030685.
Mirkovic S, Seymour AM, Fenning A, Strachan A, Margolin SB, Taylor SM, et al. (February 2002). "Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats". British Journal of Pharmacology. 135 (4): 961–8. doi:10.1038/sj.bjp.0704539. PMC 1573203. PMID 11861324.
Zhou C, Liu F, Gallo PH, Baratz ME, Kathju S, Satish L (November 2016). "Anti-fibrotic action of pirfenidone in Dupuytren's disease-derived fibroblasts". BMC Musculoskeletal Disorders. 17 (1): 469. doi:10.1186/s12891-016-1326-y. PMC 5106805. PMID 27835939.
Stougaard J, Lomholt S, Ommen P, Kelsen J, Kragstrup TW (2018). "The antifibrotic drug pirfenidone inhibits spondyloarthritis fibroblast-like synoviocytes and osteoblasts in vitro". BMC Rheumatology. 2: 33. doi:10.1186/s41927-018-0040-9. PMC 6390625. PMID 30886983.
Macías-Barragán J, Sandoval-Rodríguez A, Navarro-Partida J, Armendáriz-Borunda J (September 2010). "The multifaceted role of pirfenidone and its novel targets". Fibrogenesis & Tissue Repair. 3: 16. doi:10.1186/1755-1536-3-16. PMC 2944211. PMID 20809935.

dailymed.nlm.nih.gov

"Esbriet- pirfenidone capsule Esbriet- pirfenidone tablet, coated". DailyMed. 14 December 2022. Archived from the original on 8 January 2023. Retrieved 8 January 2023.

patentdocs.org

"InterMune Buys out License Agreement for Pirfenidone". Patent Docs. Archived from the original on 14 May 2019. Retrieved 2 November 2016.

semanticscholar.org

api.semanticscholar.org

Liu H, Drew P, Gaugler AC, Cheng Y, Visner GA (June 2005). "Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway". Am. J. Transplant. 5 (6): 1256–63. doi:10.1111/j.1600-6143.2005.00876.x. PMID 15888029. S2CID 24236706.
Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, et al. (May 2011). "Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials". Lancet. 377 (9779): 1760–9. doi:10.1016/S0140-6736(11)60405-4. PMID 21571362. S2CID 10119356.

swissinfo.ch

"Swiss pharma giants Roche and Novartis fight over patent in US court". Swissinfo. 2 August 2023. Retrieved 3 August 2023.

tga.gov.au

"Prescription medicines: registration of new chemical entities in Australia, 2016". Therapeutic Goods Administration (TGA). 21 June 2022. Archived from the original on 10 April 2023. Retrieved 10 April 2023.

web.archive.org

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Manjusha P, Prasana JC, Muthu S, Raajaraman BR (5 March 2020). "Density functional studies and spectroscopic analysis (FT-IR, FT-Raman, UV–visible, and NMR)with molecular docking approach on an antifibrotic drug Pirfenidone". Journal of Molecular Structure. 1203: 127394. Bibcode:2020JMoSt120327394M. doi:10.1016/j.molstruc.2019.127394. ISSN 0022-2860.

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