Receptor activated solely by a synthetic ligand (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Receptor activated solely by a synthetic ligand" in English language version.

refsWebsite

Global rank English rank

39nih.gov

4^th place

21doi.org

2^nd place

11worldcat.org

5^th place

5harvard.edu

18^th place

17^th place

3hellobio.com

low place

2semanticscholar.org

11^th place

8^th place

1nature.com

234^th place

397^th place

1creativecommons.org

1,010^th place

612^th place

1pressbooks.pub

low place

1jstor.org

26^th place

20^th place

creativecommons.org (Global: 1,010^th place; English: 612^th place)

This article incorporates text available under the CC BY 4.0 license. Ju, William (November 1, 2023). Neuroscience. Toronto: University of Toronto. 3.4 Chemogenic methods to examine the brain behaviour.

doi.org (Global: 2^nd place; English: 2^nd place)

Roth BL (February 2016). "DREADDs for Neuroscientists". Neuron. 89 (4): 683–94. doi:10.1016/j.neuron.2016.01.040. PMC 4759656. PMID 26889809.
Campbell, Erin J.; Marchant, Nathan J. (April 2018). "The use of chemogenetics in behavioural neuroscience: receptor variants, targeting approaches and caveats". British Journal of Pharmacology. 175 (7): 994–1003. doi:10.1111/bph.14146. ISSN 1476-5381. PMC 5843707. PMID 29338070.
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–8. doi:10.1038/nmeth.1232. PMC 2703467. PMID 18668035.
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL (March 2007). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–8. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. PMC 1829280. PMID 17360345.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Vardy, Eyal; Robinson, J. Elliott; Li, Chia; Olsen, Reid H. J.; DiBerto, Jeffrey F.; Giguere, Patrick M.; Sassano, Flori M.; Huang, Xi-Ping; Zhu, Hu (2015-05-20). "A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior". Neuron. 86 (4): 936–946. doi:10.1016/j.neuron.2015.03.065. ISSN 1097-4199. PMC 4441592. PMID 25937170.
Conklin, Bruce R.; Hsiao, Edward C.; Claeysen, Sylvie; Dumuis, Aline; Srinivasan, Supriya; Forsayeth, John R.; Guettier, Jean-Marc; Chang, W. C.; Pei, Ying (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–678. doi:10.1038/nmeth.1232. ISSN 1548-7105. PMC 2703467. PMID 18668035.
Wess, Jürgen; Nakajima, Kenichiro; Jain, Shalini (July 2013). "Novel designer receptors to probe GPCR signaling and physiology". Trends in Pharmacological Sciences. 34 (7): 385–392. doi:10.1016/j.tips.2013.04.006. ISSN 1873-3735. PMC 3758874. PMID 23769625.
Gomez, Juan L.; Bonaventura, Jordi; Lesniak, Wojciech; Mathews, William B.; Sysa-Shah, Polina; Rodriguez, Lionel A.; Ellis, Randall J.; Richie, Christopher T.; Harvey, Brandon K. (August 4, 2017). "Chemogenetics revealed: DREADD occupancy and activation via converted clozapine". Science. 357 (6350): 503–507. Bibcode:2017Sci...357..503G. doi:10.1126/science.aan2475. ISSN 1095-9203. PMC 7309169. PMID 28774929.
Thompson, Karen J.; Khajehali, Elham; Bradley, Sophie J.; Navarrete, Jovana S.; Huang, Xi Ping; Slocum, Samuel; Jin, Jian; Liu, Jing; Xiong, Yan (2018-09-14). "DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo". ACS Pharmacology & Translational Science. 1 (1): 61–72. doi:10.1021/acsptsci.8b00012. PMC 6407913. PMID 30868140.
Chen, Xin; Choo, Hyunah; Huang, Xi-Ping; Yang, Xiaobao; Stone, Orrin; Roth, Bryan L.; Jin, Jian (2015-03-18). "The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs". ACS Chemical Neuroscience. 6 (3): 476–484. doi:10.1021/cn500325v. ISSN 1948-7193. PMC 4368042. PMID 25587888.
Nagai, Yuji; Miyakawa, Naohisa; Takuwa, Hiroyuki; Hori, Yukiko; Oyama, Kei; Ji, Bin; Takahashi, Manami; Huang, Xi-Ping; Slocum, Samuel T.; DiBerto, Jeffrey F.; Xiong, Yan (September 2020). "Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys". Nature Neuroscience. 23 (9): 1157–1167. doi:10.1038/s41593-020-0661-3. ISSN 1546-1726. PMID 32632286. S2CID 220375204.
Marchant, Nathan J.; Whitaker, Leslie R.; Bossert, Jennifer M.; Harvey, Brandon K.; Hope, Bruce T.; Kaganovsky, Konstantin; Adhikary, Sweta; Prisinzano, Thomas E.; Vardy, Eyal (January 2016). "Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats". Neuropsychopharmacology. 41 (2): 402–409. doi:10.1038/npp.2015.149. ISSN 1740-634X. PMC 5130116. PMID 26019014.
Urban DJ, Roth BL (2015-01-06). "DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility". Annual Review of Pharmacology and Toxicology. 55 (1): 399–417. doi:10.1146/annurev-pharmtox-010814-124803. PMID 25292433.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Zhu H, Roth BL (May 2014). "Silencing synapses with DREADDs". Neuron. 82 (4): 723–5. doi:10.1016/j.neuron.2014.05.002. PMC 4109642. PMID 24853931.
Guettier, Jean-Marc; Gautam, Dinesh; Scarselli, Marco; Ruiz de Azua, Inigo; Li, Jian Hua; Rosemond, Erica; Ma, Xiaochao; Gonzalez, Frank J.; Armbruster, Blaine N.; Lu, Huiyan; Roth, Bryan L.; Wess, Jürgen (2009-11-10). "A chemical-genetic approach to study G protein regulation of beta cell function in vivo". Proceedings of the National Academy of Sciences of the United States of America. 106 (45): 19197–19202. doi:10.1073/pnas.0906593106. ISSN 1091-6490. PMC 2767362. PMID 19858481.
Smith RS, Hu R, DeSouza A, Eberly CL, Krahe K, Chan W, Araneda RC (July 2015). "Differential Muscarinic Modulation in the Olfactory Bulb". The Journal of Neuroscience. 35 (30): 10773–85. doi:10.1523/JNEUROSCI.0099-15.2015. PMC 4518052. PMID 26224860.
Ferguson SM, Eskenazi D, Ishikawa M, Wanat MJ, Phillips PE, Dong Y, Roth BL, Neumaier JF (January 2011). "Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization". Nature Neuroscience. 14 (1): 22–4. doi:10.1038/nn.2703. PMC 3058296. PMID 21131952.
Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR (January 1998). "Controlling signaling with a specifically designed Gi-coupled receptor". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 352–7. Bibcode:1998PNAS...95..352C. doi:10.1073/pnas.95.1.352. JSTOR 44466. PMC 18222. PMID 9419379.
Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ (March 2005). "The receptors and coding logic for bitter taste". Nature. 434 (7030): 225–9. Bibcode:2005Natur.434..225M. doi:10.1038/nature03352. PMID 15759003. S2CID 4383273.

harvard.edu (Global: 18^th place; English: 17^th place)

ui.adsabs.harvard.edu

Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL (March 2007). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–8. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. PMC 1829280. PMID 17360345.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Gomez, Juan L.; Bonaventura, Jordi; Lesniak, Wojciech; Mathews, William B.; Sysa-Shah, Polina; Rodriguez, Lionel A.; Ellis, Randall J.; Richie, Christopher T.; Harvey, Brandon K. (August 4, 2017). "Chemogenetics revealed: DREADD occupancy and activation via converted clozapine". Science. 357 (6350): 503–507. Bibcode:2017Sci...357..503G. doi:10.1126/science.aan2475. ISSN 1095-9203. PMC 7309169. PMID 28774929.
Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR (January 1998). "Controlling signaling with a specifically designed Gi-coupled receptor". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 352–7. Bibcode:1998PNAS...95..352C. doi:10.1073/pnas.95.1.352. JSTOR 44466. PMC 18222. PMID 9419379.
Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ (March 2005). "The receptors and coding logic for bitter taste". Nature. 434 (7030): 225–9. Bibcode:2005Natur.434..225M. doi:10.1038/nature03352. PMID 15759003. S2CID 4383273.

hellobio.com (Global: low place; English: low place)

"DREADD ligands (CNO / SalB) for neuroscience research". HelloBio.com. Retrieved 2018-12-05.
"Stability of Water-Soluble DREADD Ligands in Solution - A Technical Review". HelloBio.com. Retrieved 2018-12-05.
"Clozapine N-oxide (CNO) freebase stability and storage". HelloBio.com. Retrieved 2018-12-05.

jstor.org (Global: 26^th place; English: 20^th place)

Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR (January 1998). "Controlling signaling with a specifically designed Gi-coupled receptor". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 352–7. Bibcode:1998PNAS...95..352C. doi:10.1073/pnas.95.1.352. JSTOR 44466. PMC 18222. PMID 9419379.

nature.com (Global: 234^th place; English: 397^th place)

Nagai, Yuji; Miyakawa, Naohisa; Takuwa, Hiroyuki; Hori, Yukiko; Oyama, Kei; Ji, Bin; Takahashi, Manami; Huang, Xi-Ping; Slocum, Samuel T.; DiBerto, Jeffrey F.; Xiong, Yan (September 2020). "Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys". Nature Neuroscience. 23 (9): 1157–1167. doi:10.1038/s41593-020-0661-3. ISSN 1546-1726. PMID 32632286. S2CID 220375204.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Roth BL (February 2016). "DREADDs for Neuroscientists". Neuron. 89 (4): 683–94. doi:10.1016/j.neuron.2016.01.040. PMC 4759656. PMID 26889809.
Campbell, Erin J.; Marchant, Nathan J. (April 2018). "The use of chemogenetics in behavioural neuroscience: receptor variants, targeting approaches and caveats". British Journal of Pharmacology. 175 (7): 994–1003. doi:10.1111/bph.14146. ISSN 1476-5381. PMC 5843707. PMID 29338070.
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–8. doi:10.1038/nmeth.1232. PMC 2703467. PMID 18668035.
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL (March 2007). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–8. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. PMC 1829280. PMID 17360345.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Vardy, Eyal; Robinson, J. Elliott; Li, Chia; Olsen, Reid H. J.; DiBerto, Jeffrey F.; Giguere, Patrick M.; Sassano, Flori M.; Huang, Xi-Ping; Zhu, Hu (2015-05-20). "A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior". Neuron. 86 (4): 936–946. doi:10.1016/j.neuron.2015.03.065. ISSN 1097-4199. PMC 4441592. PMID 25937170.
Conklin, Bruce R.; Hsiao, Edward C.; Claeysen, Sylvie; Dumuis, Aline; Srinivasan, Supriya; Forsayeth, John R.; Guettier, Jean-Marc; Chang, W. C.; Pei, Ying (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–678. doi:10.1038/nmeth.1232. ISSN 1548-7105. PMC 2703467. PMID 18668035.
Wess, Jürgen; Nakajima, Kenichiro; Jain, Shalini (July 2013). "Novel designer receptors to probe GPCR signaling and physiology". Trends in Pharmacological Sciences. 34 (7): 385–392. doi:10.1016/j.tips.2013.04.006. ISSN 1873-3735. PMC 3758874. PMID 23769625.
Gomez, Juan L.; Bonaventura, Jordi; Lesniak, Wojciech; Mathews, William B.; Sysa-Shah, Polina; Rodriguez, Lionel A.; Ellis, Randall J.; Richie, Christopher T.; Harvey, Brandon K. (August 4, 2017). "Chemogenetics revealed: DREADD occupancy and activation via converted clozapine". Science. 357 (6350): 503–507. Bibcode:2017Sci...357..503G. doi:10.1126/science.aan2475. ISSN 1095-9203. PMC 7309169. PMID 28774929.
Thompson, Karen J.; Khajehali, Elham; Bradley, Sophie J.; Navarrete, Jovana S.; Huang, Xi Ping; Slocum, Samuel; Jin, Jian; Liu, Jing; Xiong, Yan (2018-09-14). "DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo". ACS Pharmacology & Translational Science. 1 (1): 61–72. doi:10.1021/acsptsci.8b00012. PMC 6407913. PMID 30868140.
Chen, Xin; Choo, Hyunah; Huang, Xi-Ping; Yang, Xiaobao; Stone, Orrin; Roth, Bryan L.; Jin, Jian (2015-03-18). "The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs". ACS Chemical Neuroscience. 6 (3): 476–484. doi:10.1021/cn500325v. ISSN 1948-7193. PMC 4368042. PMID 25587888.
Nagai, Yuji; Miyakawa, Naohisa; Takuwa, Hiroyuki; Hori, Yukiko; Oyama, Kei; Ji, Bin; Takahashi, Manami; Huang, Xi-Ping; Slocum, Samuel T.; DiBerto, Jeffrey F.; Xiong, Yan (September 2020). "Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys". Nature Neuroscience. 23 (9): 1157–1167. doi:10.1038/s41593-020-0661-3. ISSN 1546-1726. PMID 32632286. S2CID 220375204.
Marchant, Nathan J.; Whitaker, Leslie R.; Bossert, Jennifer M.; Harvey, Brandon K.; Hope, Bruce T.; Kaganovsky, Konstantin; Adhikary, Sweta; Prisinzano, Thomas E.; Vardy, Eyal (January 2016). "Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats". Neuropsychopharmacology. 41 (2): 402–409. doi:10.1038/npp.2015.149. ISSN 1740-634X. PMC 5130116. PMID 26019014.
Urban DJ, Roth BL (2015-01-06). "DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility". Annual Review of Pharmacology and Toxicology. 55 (1): 399–417. doi:10.1146/annurev-pharmtox-010814-124803. PMID 25292433.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Zhu H, Roth BL (May 2014). "Silencing synapses with DREADDs". Neuron. 82 (4): 723–5. doi:10.1016/j.neuron.2014.05.002. PMC 4109642. PMID 24853931.
Guettier, Jean-Marc; Gautam, Dinesh; Scarselli, Marco; Ruiz de Azua, Inigo; Li, Jian Hua; Rosemond, Erica; Ma, Xiaochao; Gonzalez, Frank J.; Armbruster, Blaine N.; Lu, Huiyan; Roth, Bryan L.; Wess, Jürgen (2009-11-10). "A chemical-genetic approach to study G protein regulation of beta cell function in vivo". Proceedings of the National Academy of Sciences of the United States of America. 106 (45): 19197–19202. doi:10.1073/pnas.0906593106. ISSN 1091-6490. PMC 2767362. PMID 19858481.
Smith RS, Hu R, DeSouza A, Eberly CL, Krahe K, Chan W, Araneda RC (July 2015). "Differential Muscarinic Modulation in the Olfactory Bulb". The Journal of Neuroscience. 35 (30): 10773–85. doi:10.1523/JNEUROSCI.0099-15.2015. PMC 4518052. PMID 26224860.
Ferguson SM, Eskenazi D, Ishikawa M, Wanat MJ, Phillips PE, Dong Y, Roth BL, Neumaier JF (January 2011). "Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization". Nature Neuroscience. 14 (1): 22–4. doi:10.1038/nn.2703. PMC 3058296. PMID 21131952.
Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR (January 1998). "Controlling signaling with a specifically designed Gi-coupled receptor". Proceedings of the National Academy of Sciences of the United States of America. 95 (1): 352–7. Bibcode:1998PNAS...95..352C. doi:10.1073/pnas.95.1.352. JSTOR 44466. PMC 18222. PMID 9419379.
Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ (March 2005). "The receptors and coding logic for bitter taste". Nature. 434 (7030): 225–9. Bibcode:2005Natur.434..225M. doi:10.1038/nature03352. PMID 15759003. S2CID 4383273.

ncbi.nlm.nih.gov

Roth BL (February 2016). "DREADDs for Neuroscientists". Neuron. 89 (4): 683–94. doi:10.1016/j.neuron.2016.01.040. PMC 4759656. PMID 26889809.
Campbell, Erin J.; Marchant, Nathan J. (April 2018). "The use of chemogenetics in behavioural neuroscience: receptor variants, targeting approaches and caveats". British Journal of Pharmacology. 175 (7): 994–1003. doi:10.1111/bph.14146. ISSN 1476-5381. PMC 5843707. PMID 29338070.
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–8. doi:10.1038/nmeth.1232. PMC 2703467. PMID 18668035.
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL (March 2007). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–8. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. PMC 1829280. PMID 17360345.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. Bibcode:2007PNAS..104.5163A. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Vardy, Eyal; Robinson, J. Elliott; Li, Chia; Olsen, Reid H. J.; DiBerto, Jeffrey F.; Giguere, Patrick M.; Sassano, Flori M.; Huang, Xi-Ping; Zhu, Hu (2015-05-20). "A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior". Neuron. 86 (4): 936–946. doi:10.1016/j.neuron.2015.03.065. ISSN 1097-4199. PMC 4441592. PMID 25937170.
Conklin, Bruce R.; Hsiao, Edward C.; Claeysen, Sylvie; Dumuis, Aline; Srinivasan, Supriya; Forsayeth, John R.; Guettier, Jean-Marc; Chang, W. C.; Pei, Ying (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–678. doi:10.1038/nmeth.1232. ISSN 1548-7105. PMC 2703467. PMID 18668035.
Wess, Jürgen; Nakajima, Kenichiro; Jain, Shalini (July 2013). "Novel designer receptors to probe GPCR signaling and physiology". Trends in Pharmacological Sciences. 34 (7): 385–392. doi:10.1016/j.tips.2013.04.006. ISSN 1873-3735. PMC 3758874. PMID 23769625.
Gomez, Juan L.; Bonaventura, Jordi; Lesniak, Wojciech; Mathews, William B.; Sysa-Shah, Polina; Rodriguez, Lionel A.; Ellis, Randall J.; Richie, Christopher T.; Harvey, Brandon K. (August 4, 2017). "Chemogenetics revealed: DREADD occupancy and activation via converted clozapine". Science. 357 (6350): 503–507. Bibcode:2017Sci...357..503G. doi:10.1126/science.aan2475. ISSN 1095-9203. PMC 7309169. PMID 28774929.
Thompson, Karen J.; Khajehali, Elham; Bradley, Sophie J.; Navarrete, Jovana S.; Huang, Xi Ping; Slocum, Samuel; Jin, Jian; Liu, Jing; Xiong, Yan (2018-09-14). "DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo". ACS Pharmacology & Translational Science. 1 (1): 61–72. doi:10.1021/acsptsci.8b00012. PMC 6407913. PMID 30868140.
Chen, Xin; Choo, Hyunah; Huang, Xi-Ping; Yang, Xiaobao; Stone, Orrin; Roth, Bryan L.; Jin, Jian (2015-03-18). "The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs". ACS Chemical Neuroscience. 6 (3): 476–484. doi:10.1021/cn500325v. ISSN 1948-7193. PMC 4368042. PMID 25587888.
Marchant, Nathan J.; Whitaker, Leslie R.; Bossert, Jennifer M.; Harvey, Brandon K.; Hope, Bruce T.; Kaganovsky, Konstantin; Adhikary, Sweta; Prisinzano, Thomas E.; Vardy, Eyal (January 2016). "Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats". Neuropsychopharmacology. 41 (2): 402–409. doi:10.1038/npp.2015.149. ISSN 1740-634X. PMC 5130116. PMID 26019014.
Armbruster, Blaine N.; Li, Xiang; Pausch, Mark H.; Herlitze, Stefan; Roth, Bryan L. (2007-03-20). "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand". Proceedings of the National Academy of Sciences of the United States of America. 104 (12): 5163–5168. doi:10.1073/pnas.0700293104. ISSN 0027-8424. PMC 1829280. PMID 17360345.
Zhu H, Roth BL (May 2014). "Silencing synapses with DREADDs". Neuron. 82 (4): 723–5. doi:10.1016/j.neuron.2014.05.002. PMC 4109642. PMID 24853931.
Guettier, Jean-Marc; Gautam, Dinesh; Scarselli, Marco; Ruiz de Azua, Inigo; Li, Jian Hua; Rosemond, Erica; Ma, Xiaochao; Gonzalez, Frank J.; Armbruster, Blaine N.; Lu, Huiyan; Roth, Bryan L.; Wess, Jürgen (2009-11-10). "A chemical-genetic approach to study G protein regulation of beta cell function in vivo". Proceedings of the National Academy of Sciences of the United States of America. 106 (45): 19197–19202. doi:10.1073/pnas.0906593106. ISSN 1091-6490. PMC 2767362. PMID 19858481.
Smith RS, Hu R, DeSouza A, Eberly CL, Krahe K, Chan W, Araneda RC (July 2015). "Differential Muscarinic Modulation in the Olfactory Bulb". The Journal of Neuroscience. 35 (30): 10773–85. doi:10.1523/JNEUROSCI.0099-15.2015. PMC 4518052. PMID 26224860.
Ferguson SM, Eskenazi D, Ishikawa M, Wanat MJ, Phillips PE, Dong Y, Roth BL, Neumaier JF (January 2011). "Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization". Nature Neuroscience. 14 (1): 22–4. doi:10.1038/nn.2703. PMC 3058296. PMID 21131952.
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Receptor activated solely by a synthetic ligand (English Wikipedia)

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