References analysis of the Wikipedia article "Renin inhibitor" in the English version

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Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP (March 2005). "Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients". Circulation. 111 (8): 1012–8. doi:10.1161/01.CIR.0000156466.02908.ED. PMID 15723979.

Nakano, Stephanie J.; Everitt, Melanie D. (2018). "Neurohormonal Axis and Natriuretic Peptides in Heart Failure". Heart Failure in the Child and Young Adult. Elsevier. pp. 75–86. doi:10.1016/b978-0-12-802393-8.00006-5. ISBN 978-0-12-802393-8.

Nussberger, Jürg (2005). "Renin Inhibitors". Hypertension. Elsevier. pp. 754–764. doi:10.1016/b978-0-7216-0258-5.50162-9. ISBN 978-0-7216-0258-5.

Lambers Heerspink, Hiddo J.; Fioretto, Paola; de Zeeuw, Dick (2014). "Pathogenesis, Pathophysiology, and Treatment of Diabetic Nephropathy". National Kidney Foundation Primer on Kidney Diseases. Elsevier. pp. 222–234. doi:10.1016/b978-1-4557-4617-0.00025-x. ISBN 978-1-4557-4617-0.

Jensen, C.; Herold, P.; Brunner, H. R. (2008). "Aliskiren: The first renin inhibitor for clinical treatment". Nature Reviews Drug Discovery. 7 (5): 399–410. doi:10.1038/nrd2550. PMID 18340340. S2CID 19633316.

Gross, F.; Lazar, J.; Orth, H. (1972). "Inhibition of the renin–angiotensinogen reaction by pepstatin". Science. 175 (22): 656. Bibcode:1972Sci...175..656G. doi:10.1126/science.175.4022.656. PMID 4109853. S2CID 8348522.

Ferrario, C. M.; Iyer, S. N. (1998). "angiotensin-(1-7): A bioactive fragment of the renin–angiotensin system". Regulatory Peptides. 78 (1–3): 13–18. doi:10.1016/s0167-0115(98)00134-7. PMID 9879742. S2CID 739207.

Phillips, M. I.; Schmidt-Ott, K. M. (1999). "The Discovery of Renin 100 Years Ago". News in Physiological Sciences. 14 (6): 271–274. doi:10.1152/physiologyonline.1999.14.6.271. PMID 11390864.

Webb, R. L.; Schiering, N.; Sedrani, R.; Maibaum, J. R. (2010). "Direct Renin Inhibitors as a New Therapy for Hypertension". Journal of Medicinal Chemistry. 53 (21): 7490–7520. doi:10.1021/jm901885s. PMID 20731374.

Wood, J. M.; Gulati, N.; Forgiarini, P.; Fuhrer, W.; Hofbauer, K. G. (1985). "Effects of a specific and long-acting renin inhibitor in the marmoset". Hypertension. 7 (5): 797–803. doi:10.1161/01.hyp.7.5.797. PMID 3928488.

Szelke, M.; Leckie, B.; Hallett, A.; Jones, D. M.; Sueiras, J.; Atrash, B.; Lever, A. F. (1982). "Potent new inhibitors of human renin". Nature. 299 (5883): 555–557. Bibcode:1982Natur.299..555S. doi:10.1038/299555a0. PMID 6750410. S2CID 4306900.

Segall, L.; Covic, A.; Goldsmith, D. J. A. (2007). "Direct renin inhibitors: The dawn of a new era, or just a variation on a theme?". Nephrology Dialysis Transplantation. 22 (9): 2435–2439. doi:10.1093/ndt/gfm363. PMID 17556409.

Nussberger, J.; Wuerzner, G.; Jensen, C.; Brunner, H. R. (2002). "Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): Comparison with enalapril". Hypertension. 39 (1): E1–E8. doi:10.1161/hy0102.102293. PMID 11799102.

Musini, VM; Fortin, PM; Bassett, K; Wright, JM (2008). "Blood pressure lowering efficacy of renin inhibitors for primary hypertension". Cochrane Database of Systematic Reviews. 4 (4): CD007066. doi:10.1002/14651858.CD007066.pub2. PMID 18843743.

Weir MR (September 2007). "Effects of renin–angiotensin system inhibition on end-organ protection: can we do better?". Clin Ther. 29 (9): 1803–24. doi:10.1016/j.clinthera.2007.09.019. PMID 18035185.

Castrop H, Höcherl K, Kurtz A, Schweda F, Todorov V, Wagner C (April 2010). "Physiology of kidney renin". Physiol. Rev. 90 (2): 607–73. CiteSeerX 10.1.1.455.1972. doi:10.1152/physrev.00011.2009. PMID 20393195.

Tice, C. M.; Xu, Z.; Yuan, J.; Simpson, R. D.; Cacatian, S. T.; Flaherty, P. T.; Zhao, W.; Guo, J.; Ishchenko, A.; Singh, S. B.; Wu, Z.; Scott, B. B.; Bukhtiyarov, Y.; Berbaum, J.; Mason, J.; Panemangalore, R.; Cappiello, M. G.; Müller, D.; Harrison, R. K.; McGeehan, G. M.; Dillard, L. W.; Baldwin, J. J.; Claremon, D. A. (2009). "Design and optimization of renin inhibitors: Orally bioavailable alkyl amines". Bioorganic & Medicinal Chemistry Letters. 19 (13): 3541–3545. doi:10.1016/j.bmcl.2009.04.140. PMID 19457666.

Ferrario, C. M. (2006). "Role of angiotensin II in cardiovascular disease therapeutic implications of more than a century of research". Journal of the Renin-Angiotensin-Aldosterone System. 7 (1): 3–14. doi:10.3317/jraas.2006.003. PMID 17083068.

Brown, M. J. (2006). "Direct renin inhibition — a new way of targeting the renin system". Journal of the Renin-Angiotensin-Aldosterone System. 7 (2 suppl): S7–S11. doi:10.3317/jraas.2006.035. S2CID 73232791.

Rahuel, J.; Rasetti, V.; Maibaum, J.; Rüeger, H.; Göschke, R.; Cohen, N. C.; Stutz, S.; Cumin, F.; Fuhrer, W.; Wood, J. M.; Grütter, M. G. (2000). "Structure-based drug design: The discovery of novel nonpeptide orally active inhibitors of human renin". Chemistry & Biology. 7 (7): 493–504. doi:10.1016/S1074-5521(00)00134-4. PMID 10903938.

Hsueh, W. A.; Wyne, K. (2011). "Renin–angiotensin–Aldosterone System in Diabetes and Hypertension". The Journal of Clinical Hypertension. 13 (4): 224–237. doi:10.1111/j.1751-7176.2011.00449.x. PMC 8673350. PMID 21466617. S2CID 23032701.

Moser M, Izzo JL (2003). "Plasma renin measurement in the management of hypertension: the V and R hypothesis". The Journal of Clinical Hypertension. 5 (6): 373–6. doi:10.1111/j.1524-6175.2003.02870.x. PMC 8099254. PMID 14688491. S2CID 221263755.

Müller, D. N.; Derer, W.; Dechend, R. (2008). "Aliskiren—mode of action and preclinical data". Journal of Molecular Medicine. 86 (6): 659–662. doi:10.1007/s00109-008-0330-6. PMID 18443751. S2CID 23697321.

Weir, M.; Bush, C.; Anderson, D.; Zhang, J.; Keefe, D.; Satlin, A. (2007). "Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: A pooled analysis". Journal of the American Society of Hypertension. 1 (4): 264–277. doi:10.1016/j.jash.2007.04.004. PMID 20409858.

Gao D, Ning N, Niu X, Wei J, Sun P, Hao G (May 2011). "Aliskiren vs. angiotensin receptor blockers in hypertension: meta-analysis of randomized controlled trials". Am. J. Hypertens. 24 (5): 613–21. doi:10.1038/ajh.2011.3. PMID 21293386.

Staessen, J. A.; Li, Y.; Richart, T. (2006). "Oral renin inhibitors". The Lancet. 368 (9545): 1449–1456. doi:10.1016/S0140-6736(06)69442-7. PMID 17055947. S2CID 20729350.

Umezawa, H.; Aoyagi, T.; Morishima, H.; Matsuzaki, M.; Hamada, M.; Takeuchi, T. (1970). "Pepstatin, a new pepsin inhibitor produced by Actinomycetes". The Journal of Antibiotics. 23 (5): 259–262. doi:10.7164/antibiotics.23.259. PMID 4912600.

Fisher, N. D. L.; Hollenberg, N. K. (2005). "Renin Inhibition: What Are the Therapeutic Opportunities?". Journal of the American Society of Nephrology. 16 (3): 592–599. doi:10.1681/ASN.2004100874. PMID 15703270.

Bonnevie, O.; Svendsen, L. B.; Holst-Christensen, J.; Johansen, T. S.; Søltoft, J.; Christiansen, P. M. (1979). "Double-blind randomised clinical trial of a pepsin-inhibitory pentapeptide (pepstatin) in the treatment of duodenal ulcer". Gut. 20 (7): 624–628. doi:10.1136/gut.20.7.624. PMC 1412504. PMID 385457.

Marciniszyn Jr, J.; Hartsuck, J. A.; Tang, J. (1976). "Mode of inhibition of acid proteases by pepstatin". The Journal of Biological Chemistry. 251 (22): 7088–7094. doi:10.1016/S0021-9258(17)32945-9. PMID 993206.

Eid, M.; Evin, G.; Castro, B.; Menard, J.; Corvol, P. (1981). "New renin inhibitors homologous with pepstatin". The Biochemical Journal. 197 (2): 465–471. doi:10.1042/bj1970465. PMC 1163147. PMID 7034718.

Cumin, F.; Evin, G.; Fehrentz, J. A.; Seyer, R.; Castro, B.; Menard, J.; et al. (1985). "Inhibition of human renin by synthetic peptides derived from its prosegment". J Biol Chem. 260 (16): 9154–9157. doi:10.1016/S0021-9258(17)39344-4. PMID 3894354.

Szelke, M.; Leckie, B. J.; Tree, M.; Brown, A.; Grant, J.; Hallett, A.; et al. (1982). "H-77: a potent new renin inhibitor. In vitro and in vivo studies". Hypertension. 4 (3 Pt 2): 59–69. doi:10.1161/01.HYP.4.3_Pt_2.59. PMID 7040240.

Tree, M.; Atrash, B.; Donovan, B.; Gamble, J.; Hallett, A.; Hughes, M.; Jones, D. M.; Leckie, B.; Lever, A. F.; Morton, J. J.; Szelke, M. (1983). "New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon". Journal of Hypertension. 1 (4): 399–403. doi:10.1097/00004872-198312000-00013. PMID 6398331.

Webb, D. J.; Manhem, P. J.; Ball, S. G.; Inglis, G.; Leckie, B. J.; Lever, A. F.; Morton, J. J.; Robertson, J. I.; Murray, G. D.; Ménard, J.; Hallett, A.; Jones, D. M.; Szelke, M. (1985). "A study of the renin inhibitor H142 in man". Journal of Hypertension. 3 (6): 653–658. doi:10.1097/00004872-198512000-00013. PMID 3910726.

Riccioni, Graziano (2013-06-14). "The role of direct renin inhibitors in the treatment of the hypertensive diabetic patient". Therapeutic Advances in Endocrinology and Metabolism. 4 (5). SAGE Publications: 139–145. doi:10.1177/2042018813490779. ISSN 2042-0188. PMC 3799297. PMID 24143271.

Claude Cohen, N. (2007). "Structure-Based Drug Design and the Discovery of Aliskiren (Tekturna): Perseverance and Creativity to Overcome a R&D Pipeline Challenge". Chemical Biology & Drug Design. 70 (6): 557–565. doi:10.1111/j.1747-0285.2007.00599.x. PMID 17999663. S2CID 221550002.

Gradman, A. H.; Kad, R. (2008). "Renin inhibition in hypertension. [Review]". J Am Coll Cardiol. 51 (5): 519–528. doi:10.1016/j.jacc.2007.10.027. PMID 18237679.

Lunney, E. A.; Hamilton, H. W.; Hodges, J. C.; Kaltenbronn, J. S.; Repine, J. T.; Badasso, M.; Cooper, J. B.; Dealwis, C.; Wallace, B. A.; Lowther, W. T. (1993). "Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors". Journal of Medicinal Chemistry. 36 (24): 3809–3820. doi:10.1021/jm00076a008. PMID 8254610.

Matter, H.; Scheiper, B.; Steinhagen, H.; Böcskei, Z.; Fleury, V. R.; McCort, G. (2011). "Structure-based design and optimization of potent renin inhibitors on 5- or 7-azaindole-scaffolds". Bioorganic & Medicinal Chemistry Letters. 21 (18): 5487–5492. doi:10.1016/j.bmcl.2011.06.112. PMID 21840215.

Yuan, J.; Simpson, R. D.; Zhao, W.; Tice, C. M.; Xu, Z.; Cacatian, S.; Jia, L.; Flaherty, P. T.; Guo, J.; Ishchenko, A.; Wu, Z.; McKeever, B. M.; Scott, B. B.; Bukhtiyarov, Y.; Berbaum, J.; Panemangalore, R.; Bentley, R.; Doe, C. P.; Harrison, R. K.; McGeehan, G. M.; Singh, S. B.; Dillard, L. W.; Baldwin, J. J.; Claremon, D. A. (2011). "Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket". Bioorganic & Medicinal Chemistry Letters. 21 (16): 4836–4843. doi:10.1016/j.bmcl.2011.06.043. PMID 21741239.

Wood, J. M.; Maibaum, J.; Rahuel, J.; Grütter, M. G.; Cohen, N. C.; Rasetti, V.; Rüger, H.; Göschke, R.; Stutz, S.; Fuhrer, W.; Schilling, W.; Rigollier, P.; Yamaguchi, Y.; Cumin, F.; Baum, H. P.; Schnell, C. R.; Herold, P.; Mah, R.; Jensen, C.; O'Brien, E.; Stanton, A.; Bedigian, M. P. (2003). "Structure-based design of aliskiren, a novel orally effective renin inhibitor". Biochemical and Biophysical Research Communications. 308 (4): 698–705. doi:10.1016/S0006-291X(03)01451-7. PMID 12927775.

Politi, A.; Durdagi, S.; Moutevelis-Minakakis, P.; Kokotos, G.; Mavromoustakos, T. (2010). "Development of accurate binding affinity predictions of novel renin inhibitors through molecular docking studies". Journal of Molecular Graphics and Modelling. 29 (3): 425–435. doi:10.1016/j.jmgm.2010.08.003. PMID 20855222.

Akahane, K.; Umeyama, H.; Nakagawa, S.; Moriguchi, I.; Hirose, S.; Iizuka, K.; Murakami, K. (1985). "Three-dimensional structure of human renin". Hypertension. 7 (1): 3–12. doi:10.1161/01.hyp.7.1.3. PMID 3884499.

Wu, Y.; Shi, C.; Sun, X.; Wu, X.; Sun, H. (2011). "Synthesis, biological evaluation and docking studies of octane–carboxamide based renin inhibitors with extended segments toward S3′ site of renin". Bioorganic & Medicinal Chemistry. 19 (14): 4238–4249. doi:10.1016/j.bmc.2011.05.059. PMID 21708467.

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Phillips, M. I.; Schmidt-Ott, K. M. (1999). "The Discovery of Renin 100 Years Ago". News in Physiological Sciences. 14 (6): 271–274. doi:10.1152/physiologyonline.1999.14.6.271. PMID 11390864.

Staessen, J. A.; Li, Y.; Richart, T. (2006). "Oral renin inhibitors". The Lancet. 368 (9545): 1449–1456. doi:10.1016/S0140-6736(06)69442-7. PMID 17055947. S2CID 20729350.

Svendsen, L. B.; Christiansen, P. M.; Bonnevie, O. (1979). "Gastric ulcer therapy with a pepsin-inactivating peptide, pepstatin: A double-blind randomized clinical trial". Scandinavian Journal of Gastroenterology. 14 (8): 929–932. PMID 394302.

Winiecka, I.; Dudkiewicz-Wilczyńska, J.; Roman, I.; Paruszewski, R. (2010). "New potential renin inhibitors with dipeptide replacements in the molecule". Acta Poloniae Pharmaceutica. 67 (4): 367–374. PMID 20635532.

Gradman, A. H.; Kad, R. (2008). "Renin inhibition in hypertension. [Review]". J Am Coll Cardiol. 51 (5): 519–528. doi:10.1016/j.jacc.2007.10.027. PMID 18237679.

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Staessen, J. A.; Li, Y.; Richart, T. (2006). "Oral renin inhibitors". The Lancet. 368 (9545): 1449–1456. doi:10.1016/S0140-6736(06)69442-7. PMID 17055947. S2CID 20729350.

Renin inhibitor (English Wikipedia)

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