Derbalah, Abdallah; Karpick, Hayley Christine; Maize, Holly; Skersick, Preston; Cottrell, Mackenzie; Rao, Gauri G. (2022-07-01). "Role of islatravir in HIV treatment and prevention: an update". Current Opinion in HIV and AIDS. 17 (4): 240–246. doi:10.1097/COH.0000000000000740. ISSN1746-6318. PMID35762379. S2CID250078665.
Shafer, RW; Kozal, MJ; Winters, MA; Iversen, AK; Katzenstein, DA; Ragni, MV; Meyer, WA III; Gupta, P; et al. (1994). "Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations". The Journal of Infectious Diseases. 169 (4): 722–9. doi:10.1093/infdis/169.4.722. PMID8133086.
Maeda, Y; Venzon, DJ; Mitsuya, H (1998). "Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance". The Journal of Infectious Diseases. 177 (5): 1207–13. doi:10.1086/515282. PMID9593005.
Arion, D; Kaushik, N; McCormick, S; Borkow, G; Parniak, MA (1998). "Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase". Biochemistry. 37 (45): 15908–17. doi:10.1021/bi981200e. PMID9843396.
De Clercq, E (1998). "The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection". Antiviral Research. 38 (3): 153–79. doi:10.1016/S0166-3542(98)00025-4. PMID9754886.
Das, Kalyan; Sarafianos, SG; Clark Jr, AD; Boyer, PL; Hughes, SH; Arnold, E (2007). "Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097". J Mol Biol. 365 (1): 77–89. doi:10.1016/j.jmb.2006.08.097. PMID17056061.
Hsiou, Y; Ding, J; Das, K; Clark Jr, AD; Boyer, PL; Lewi, P; Janssen, PA; Kleim, JP; et al. (2001). "The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance". Journal of Molecular Biology. 309 (2): 437–45. doi:10.1006/jmbi.2001.4648. PMID11371163. S2CID3109889.
Ren, J; Nichols, C; Bird, L; Chamberlain, P; Weaver, K; Short, S; Stuart, DI; Stammers, DK (2001). "Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors". Journal of Molecular Biology. 312 (4): 795–805. doi:10.1006/jmbi.2001.4988. PMID11575933.
Das, K; Ding, J; Hsiou, Y; Clark Jr, AD; Moereels, H; Koymans, L; Andries, K; Pauwels, R; et al. (1996). "Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant". Journal of Molecular Biology. 264 (5): 1085–100. doi:10.1006/jmbi.1996.0698. PMID9000632.
Hsiou, Y; Das, K; Ding, J; Clark Jr, AD; Kleim, JP; Rösner, M; Winkler, I; Riess, G; et al. (1998). "Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance". Journal of Molecular Biology. 284 (2): 313–23. doi:10.1006/jmbi.1998.2171. PMID9813120.
Ren, J; Esnouf, R; Garman, E; Somers, D; Ross, C; Kirby, I; Keeling, J; Darby, G; et al. (1995). "High resolution structures of HIV-1 RT from four RT-inhibitor complexes". Nature Structural Biology. 2 (4): 293–302. doi:10.1038/nsb0495-293. PMID7540934. S2CID34618424.
Derbalah, Abdallah; Karpick, Hayley Christine; Maize, Holly; Skersick, Preston; Cottrell, Mackenzie; Rao, Gauri G. (2022-07-01). "Role of islatravir in HIV treatment and prevention: an update". Current Opinion in HIV and AIDS. 17 (4): 240–246. doi:10.1097/COH.0000000000000740. ISSN1746-6318. PMID35762379. S2CID250078665.
Shafer, RW; Kozal, MJ; Winters, MA; Iversen, AK; Katzenstein, DA; Ragni, MV; Meyer, WA III; Gupta, P; et al. (1994). "Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations". The Journal of Infectious Diseases. 169 (4): 722–9. doi:10.1093/infdis/169.4.722. PMID8133086.
Maeda, Y; Venzon, DJ; Mitsuya, H (1998). "Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance". The Journal of Infectious Diseases. 177 (5): 1207–13. doi:10.1086/515282. PMID9593005.
Arion, D; Kaushik, N; McCormick, S; Borkow, G; Parniak, MA (1998). "Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase". Biochemistry. 37 (45): 15908–17. doi:10.1021/bi981200e. PMID9843396.
De Clercq, E (1998). "The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection". Antiviral Research. 38 (3): 153–79. doi:10.1016/S0166-3542(98)00025-4. PMID9754886.
Johnson, VA; Brun-Vezinet, F; Clotet, B; Gunthard, HF; Kuritzkes, DR; Pillay, D; Schapiro, JM; Richman, DD (2009). "Update of the drug resistance mutations in HIV-1: December 2009". Topics in HIV Medicine. 17 (5): 138–45. PMID20068260.
Das, Kalyan; Sarafianos, SG; Clark Jr, AD; Boyer, PL; Hughes, SH; Arnold, E (2007). "Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097". J Mol Biol. 365 (1): 77–89. doi:10.1016/j.jmb.2006.08.097. PMID17056061.
Hsiou, Y; Ding, J; Das, K; Clark Jr, AD; Boyer, PL; Lewi, P; Janssen, PA; Kleim, JP; et al. (2001). "The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance". Journal of Molecular Biology. 309 (2): 437–45. doi:10.1006/jmbi.2001.4648. PMID11371163. S2CID3109889.
Ren, J; Nichols, C; Bird, L; Chamberlain, P; Weaver, K; Short, S; Stuart, DI; Stammers, DK (2001). "Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors". Journal of Molecular Biology. 312 (4): 795–805. doi:10.1006/jmbi.2001.4988. PMID11575933.
Das, K; Ding, J; Hsiou, Y; Clark Jr, AD; Moereels, H; Koymans, L; Andries, K; Pauwels, R; et al. (1996). "Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant". Journal of Molecular Biology. 264 (5): 1085–100. doi:10.1006/jmbi.1996.0698. PMID9000632.
Hsiou, Y; Das, K; Ding, J; Clark Jr, AD; Kleim, JP; Rösner, M; Winkler, I; Riess, G; et al. (1998). "Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance". Journal of Molecular Biology. 284 (2): 313–23. doi:10.1006/jmbi.1998.2171. PMID9813120.
Ren, J; Esnouf, R; Garman, E; Somers, D; Ross, C; Kirby, I; Keeling, J; Darby, G; et al. (1995). "High resolution structures of HIV-1 RT from four RT-inhibitor complexes". Nature Structural Biology. 2 (4): 293–302. doi:10.1038/nsb0495-293. PMID7540934. S2CID34618424.
Derbalah, Abdallah; Karpick, Hayley Christine; Maize, Holly; Skersick, Preston; Cottrell, Mackenzie; Rao, Gauri G. (2022-07-01). "Role of islatravir in HIV treatment and prevention: an update". Current Opinion in HIV and AIDS. 17 (4): 240–246. doi:10.1097/COH.0000000000000740. ISSN1746-6318. PMID35762379. S2CID250078665.
Derbalah, Abdallah; Karpick, Hayley Christine; Maize, Holly; Skersick, Preston; Cottrell, Mackenzie; Rao, Gauri G. (2022-07-01). "Role of islatravir in HIV treatment and prevention: an update". Current Opinion in HIV and AIDS. 17 (4): 240–246. doi:10.1097/COH.0000000000000740. ISSN1746-6318. PMID35762379. S2CID250078665.