Analysis of information sources in references of the Wikipedia article "Rous sarcoma virus" in English language version.
The replication competent strains of Rous sarcoma virus (RSV) are exceptional in that they contain a complete set of replicative genes in addition to the transduced oncogene sequences. In this respect, they differ markedly from all other acutely transforming retroviruses, in which a large part of the replicative genes have been lost during transduction of cellular proto-oncogenes. However, since both the Bryan strain of RSV (Lerner & Hanafusa, 1984) and RSV29 (Dutta et al., 1985), the closest isolate to the original Rous tumour virus, lack the env gene, it is likely that the ancestral virus was also replication defective.– See Vogt PK (2019) for discussion of whether PR2257 constitutes a de novo uptake.
The replication competent strains of Rous sarcoma virus (RSV) are exceptional in that they contain a complete set of replicative genes in addition to the transduced oncogene sequences. In this respect, they differ markedly from all other acutely transforming retroviruses, in which a large part of the replicative genes have been lost during transduction of cellular proto-oncogenes. However, since both the Bryan strain of RSV (Lerner & Hanafusa, 1984) and RSV29 (Dutta et al., 1985), the closest isolate to the original Rous tumour virus, lack the env gene, it is likely that the ancestral virus was also replication defective.– See Vogt PK (2019) for discussion of whether PR2257 constitutes a de novo uptake.