Analysis of information sources in references of the Wikipedia article "SARS-CoV-2 Beta variant" in English language version.
Spatiotemporal phylogeographic analysis suggests that the 501Y.V2 lineage emerged in early August (early July – end August 2020, 95% highest posterior density) in Nelson Mandela Bay.
This variant was first observed in samples from October, and since then more than 300 cases with the 501.V2 variant have been confirmed by whole genome sequencing (WGS) in South Africa
Verder zijn er inmiddels drie gevallen van de Zuid-Afrikaanse variant bekend, een andere besmettelijke mutatie van het coronavirus. (Furthermore, three cases of the South African variant, another contagious mutation of the coronavirus, are now known.)
Another 444 individuals have been found to be carrying the South African variant.
There are 20 known cases of the variant in the country that resulted from seven chains of infection.
Spatiotemporal phylogeographic analysis suggests that the 501Y.V2 lineage emerged in early August (early July – end August 2020, 95% highest posterior density) in Nelson Mandela Bay.
Chief among those is another receptor-binding-domain mutation, called E484K, that de Oliveira's team has identified in the 501Y.V2 variant.
N501Y...has been found in other countries, including the United Kingdom
...the new strain of the COVID-19 virus, known as 501V2 variant, has been detected in Botswana.
Our clinicians have also warned us that things have changed and that younger, previously healthy people are now becoming very sick.
I should note here that there's another strain in South Africa that is bringing on similar concerns. This one has eight mutations in the Spike protein, with three of them (K417N, E484K and N501Y) that may have some functional role.
The South African variant '501.V2' is characterised by N501Y, E484K and K417N mutations in the S protein – so it shares the N501Y mutation with the UK variant, but the other two mutations are not found in the UK variant. Similarly, the South African variant does not contain the 69-70del mutation that is found in the UK variant.
Mittlerweile gebe es sechs Virusnachweise bei sechs Personen aus drei Haushalten, teilte das Ministerium mit. (There are now six virus detections in six people from three households, the ministry said.)
Scientists are particularly concerned about the South African variant, named B1351... ...At least 29 cases in the UK and three in Ireland have been recorded.
Another 444 individuals have been found to be carrying the South African variant.
South Africa will suspend use of the coronavirus vaccine being developed by Oxford University and AstraZeneca after researchers found it provided "minimal protection" against mild to moderate coronavirus infections caused by the new variant first detected in that country.
