Krzak G, Willis CM, Smith JA, Pluchino S, Peruzzotti-Jametti L (January 2021). "Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation". Trends in Immunology. 42 (1): 45–58. doi:10.1016/j.it.2020.11.004. PMID33279412. S2CID227522279.
Li YH, Woo SH, Choi DH, Cho EH (August 2015). "Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells". Biochemical and Biophysical Research Communications. 463 (4): 853–8. doi:10.1016/j.bbrc.2015.06.023. PMID26051274.
Chen H, Jin C, Xie L, Wu J (February 2024). "Succinate as a signaling molecule in the mediation of liver diseases". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1870 (2): 166935. doi:10.1016/j.bbadis.2023.166935. PMID37976628. S2CID265270839.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S (May 2019). "SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity". Nature Immunology. 20 (5): 581–592. doi:10.1038/s41590-019-0372-7. hdl:10261/189024. PMID30962591. S2CID102353378.
Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM (November 2008). "Triggering the succinate receptor GPR91 on dendritic cells enhances immunity". Nature Immunology. 9 (11): 1261–9. doi:10.1038/ni.1657. PMID18820681. S2CID23526117.
Bhuniya D, Umrani D, Dave B, Salunke D, Kukreja G, Gundu J, Naykodi M, Shaikh NS, Shitole P, Kurhade S, De S, Majumdar S, Reddy SB, Tambe S, Shejul Y, Chugh A, Palle VP, Mookhtiar KA, Cully D, Vacca J, Chakravarty PK, Nargund RP, Wright SD, Graziano MP, Singh SB, Roy S, Cai TQ (June 2011). "Discovery of a potent and selective small molecule hGPR91 antagonist". Bioorganic & Medicinal Chemistry Letters. 21 (12): 3596–602. doi:10.1016/j.bmcl.2011.04.091. PMID21571530.
Prasad M, Corban MT, Henry TD, Dietz AB, Lerman LO, Lerman A (July 2020). "Promise of autologous CD34+ stem/progenitor cell therapy for treatment of cardiovascular disease". Cardiovascular Research. 116 (8): 1424–1433. doi:10.1093/cvr/cvaa027. PMID32022845.
Hakak Y, Lehmann-Bruinsma K, Phillips S, Le T, Liaw C, Connolly DT, Behan DP (May 2009). "The role of the GPR91 ligand succinate in hematopoiesis". Journal of Leukocyte Biology. 85 (5): 837–43. doi:10.1189/jlb.1008618. PMID19204147. S2CID2248388.
Pu M, Zhang J, Zeng Y, Hong F, Qi W, Yang X, Gao G, Zhou T (February 2023). "Succinate-SUCNR1 induces renal tubular cell apoptosis". American Journal of Physiology. Cell Physiology. 324 (2): C467–C476. doi:10.1152/ajpcell.00327.2022. PMID36622070. S2CID255544096.
Sell EA, Tan LH, Lin C, Bosso JV, Palmer JN, Adappa ND, Lee RJ, Kohanski MA, Reed DR, Cohen NA (August 2023). "Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium". International Forum of Allergy & Rhinology. 13 (8): 1525–1534. doi:10.1002/alr.23104. PMID36565436. S2CID255116741.
McCreath KJ, Espada S, Gálvez BG, Benito M, de Molina A, Sepúlveda P, Cervera AM (April 2015). "Targeted disruption of the SUCNR1 metabolic receptor leads to dichotomous effects on obesity". Diabetes. 64 (4): 1154–67. doi:10.2337/db14-0346. PMID25352636.
Du B, Jia X, Tian W, Yan X, Wang N, Cai D, Li X, Zhang H, Jin M, Wu N, Qiu C, Zhang Q (January 2021). "Associations of SUCNR1, GRK4, CAMK1D gene polymorphisms and the susceptibility of type 2 diabetes mellitus and essential hypertension in a northern Chinese Han population". Journal of Diabetes and Its Complications. 35 (1): 107752. doi:10.1016/j.jdiacomp.2020.107752. PMID33127268. S2CID225126632.
Li Q, Zhu Y, Wang J, Zhang Y, Pan Y, Gu R, Guo X, Wei L (February 2022). "Sedentary behaviors and gestational diabetes mellitus: A systematic review". The Journal of Obstetrics and Gynaecology Research. 48 (2): 285–299. doi:10.1111/jog.15090. PMID34750937. S2CID243863298.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S (August 2023). "Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD". Metabolism: Clinical and Experimental. 145: 155630. doi:10.1016/j.metabol.2023.155630. hdl:10230/59377. PMID37315889.
Joyal JS, Omri S, Sitaras N, Rivera JC, Sapieha P, Chemtob S (August 2012). "Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A". Acta Paediatrica. 101 (8): 819–26. doi:10.1111/j.1651-2227.2012.02692.x. PMID22497252. S2CID38844477.
Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S (October 2008). "The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis". Nature Medicine. 14 (10): 1067–76. doi:10.1038/nm.1873. PMID18836459. S2CID6249205.
Rice JE, Vannucci RC, Brierley JB (February 1981). "The influence of immaturity on hypoxic-ischemic brain damage in the rat". Annals of Neurology. 9 (2): 131–41. doi:10.1002/ana.410090206. PMID7235629. S2CID34124161.
Hamel D, Sanchez M, Duhamel F, Roy O, Honoré JC, Noueihed B, Zhou T, Nadeau-Vallée M, Hou X, Lavoie JC, Mitchell G, Mamer OA, Chemtob S (February 2014). "G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery". Arteriosclerosis, Thrombosis, and Vascular Biology. 34 (2): 285–93. doi:10.1161/ATVBAHA.113.302131. PMID24285580.
Shekher A, Puneet, Awasthee N, Kumar U, Raj R, Kumar D, Gupta SC (January 2023). "Association of altered metabolic profiles and long non-coding RNAs expression with disease severity in breast cancer patients: analysis by 1H NMR spectroscopy and RT-q-PCR". Metabolomics. 19 (2): 8. doi:10.1007/s11306-023-01972-5. PMID36710275. S2CID256362645.
Gravallese EM, Firestein GS (February 2023). "Rheumatoid Arthritis - Common Origins, Divergent Mechanisms". The New England Journal of Medicine. 388 (6): 529–542. doi:10.1056/NEJMra2103726. PMID36780677. S2CID256721972.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S (May 2019). "SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity". Nature Immunology. 20 (5): 581–592. doi:10.1038/s41590-019-0372-7. hdl:10261/189024. PMID30962591. S2CID102353378.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S (August 2023). "Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD". Metabolism: Clinical and Experimental. 145: 155630. doi:10.1016/j.metabol.2023.155630. hdl:10230/59377. PMID37315889.
Krzak G, Willis CM, Smith JA, Pluchino S, Peruzzotti-Jametti L (January 2021). "Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation". Trends in Immunology. 42 (1): 45–58. doi:10.1016/j.it.2020.11.004. PMID33279412. S2CID227522279.
Li YH, Woo SH, Choi DH, Cho EH (August 2015). "Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells". Biochemical and Biophysical Research Communications. 463 (4): 853–8. doi:10.1016/j.bbrc.2015.06.023. PMID26051274.
Chen H, Jin C, Xie L, Wu J (February 2024). "Succinate as a signaling molecule in the mediation of liver diseases". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1870 (2): 166935. doi:10.1016/j.bbadis.2023.166935. PMID37976628. S2CID265270839.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S (May 2019). "SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity". Nature Immunology. 20 (5): 581–592. doi:10.1038/s41590-019-0372-7. hdl:10261/189024. PMID30962591. S2CID102353378.
Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM (November 2008). "Triggering the succinate receptor GPR91 on dendritic cells enhances immunity". Nature Immunology. 9 (11): 1261–9. doi:10.1038/ni.1657. PMID18820681. S2CID23526117.
Bhuniya D, Umrani D, Dave B, Salunke D, Kukreja G, Gundu J, Naykodi M, Shaikh NS, Shitole P, Kurhade S, De S, Majumdar S, Reddy SB, Tambe S, Shejul Y, Chugh A, Palle VP, Mookhtiar KA, Cully D, Vacca J, Chakravarty PK, Nargund RP, Wright SD, Graziano MP, Singh SB, Roy S, Cai TQ (June 2011). "Discovery of a potent and selective small molecule hGPR91 antagonist". Bioorganic & Medicinal Chemistry Letters. 21 (12): 3596–602. doi:10.1016/j.bmcl.2011.04.091. PMID21571530.
Prasad M, Corban MT, Henry TD, Dietz AB, Lerman LO, Lerman A (July 2020). "Promise of autologous CD34+ stem/progenitor cell therapy for treatment of cardiovascular disease". Cardiovascular Research. 116 (8): 1424–1433. doi:10.1093/cvr/cvaa027. PMID32022845.
Hakak Y, Lehmann-Bruinsma K, Phillips S, Le T, Liaw C, Connolly DT, Behan DP (May 2009). "The role of the GPR91 ligand succinate in hematopoiesis". Journal of Leukocyte Biology. 85 (5): 837–43. doi:10.1189/jlb.1008618. PMID19204147. S2CID2248388.
Pu M, Zhang J, Zeng Y, Hong F, Qi W, Yang X, Gao G, Zhou T (February 2023). "Succinate-SUCNR1 induces renal tubular cell apoptosis". American Journal of Physiology. Cell Physiology. 324 (2): C467–C476. doi:10.1152/ajpcell.00327.2022. PMID36622070. S2CID255544096.
Sell EA, Tan LH, Lin C, Bosso JV, Palmer JN, Adappa ND, Lee RJ, Kohanski MA, Reed DR, Cohen NA (August 2023). "Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium". International Forum of Allergy & Rhinology. 13 (8): 1525–1534. doi:10.1002/alr.23104. PMID36565436. S2CID255116741.
McCreath KJ, Espada S, Gálvez BG, Benito M, de Molina A, Sepúlveda P, Cervera AM (April 2015). "Targeted disruption of the SUCNR1 metabolic receptor leads to dichotomous effects on obesity". Diabetes. 64 (4): 1154–67. doi:10.2337/db14-0346. PMID25352636.
Du B, Jia X, Tian W, Yan X, Wang N, Cai D, Li X, Zhang H, Jin M, Wu N, Qiu C, Zhang Q (January 2021). "Associations of SUCNR1, GRK4, CAMK1D gene polymorphisms and the susceptibility of type 2 diabetes mellitus and essential hypertension in a northern Chinese Han population". Journal of Diabetes and Its Complications. 35 (1): 107752. doi:10.1016/j.jdiacomp.2020.107752. PMID33127268. S2CID225126632.
Li Q, Zhu Y, Wang J, Zhang Y, Pan Y, Gu R, Guo X, Wei L (February 2022). "Sedentary behaviors and gestational diabetes mellitus: A systematic review". The Journal of Obstetrics and Gynaecology Research. 48 (2): 285–299. doi:10.1111/jog.15090. PMID34750937. S2CID243863298.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S (August 2023). "Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD". Metabolism: Clinical and Experimental. 145: 155630. doi:10.1016/j.metabol.2023.155630. hdl:10230/59377. PMID37315889.
Joyal JS, Omri S, Sitaras N, Rivera JC, Sapieha P, Chemtob S (August 2012). "Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A". Acta Paediatrica. 101 (8): 819–26. doi:10.1111/j.1651-2227.2012.02692.x. PMID22497252. S2CID38844477.
Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S (October 2008). "The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis". Nature Medicine. 14 (10): 1067–76. doi:10.1038/nm.1873. PMID18836459. S2CID6249205.
Rice JE, Vannucci RC, Brierley JB (February 1981). "The influence of immaturity on hypoxic-ischemic brain damage in the rat". Annals of Neurology. 9 (2): 131–41. doi:10.1002/ana.410090206. PMID7235629. S2CID34124161.
Hamel D, Sanchez M, Duhamel F, Roy O, Honoré JC, Noueihed B, Zhou T, Nadeau-Vallée M, Hou X, Lavoie JC, Mitchell G, Mamer OA, Chemtob S (February 2014). "G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery". Arteriosclerosis, Thrombosis, and Vascular Biology. 34 (2): 285–93. doi:10.1161/ATVBAHA.113.302131. PMID24285580.
Shekher A, Puneet, Awasthee N, Kumar U, Raj R, Kumar D, Gupta SC (January 2023). "Association of altered metabolic profiles and long non-coding RNAs expression with disease severity in breast cancer patients: analysis by 1H NMR spectroscopy and RT-q-PCR". Metabolomics. 19 (2): 8. doi:10.1007/s11306-023-01972-5. PMID36710275. S2CID256362645.
Gravallese EM, Firestein GS (February 2023). "Rheumatoid Arthritis - Common Origins, Divergent Mechanisms". The New England Journal of Medicine. 388 (6): 529–542. doi:10.1056/NEJMra2103726. PMID36780677. S2CID256721972.
ncbi.nlm.nih.gov
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Krzak G, Willis CM, Smith JA, Pluchino S, Peruzzotti-Jametti L (January 2021). "Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation". Trends in Immunology. 42 (1): 45–58. doi:10.1016/j.it.2020.11.004. PMID33279412. S2CID227522279.
Chen H, Jin C, Xie L, Wu J (February 2024). "Succinate as a signaling molecule in the mediation of liver diseases". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1870 (2): 166935. doi:10.1016/j.bbadis.2023.166935. PMID37976628. S2CID265270839.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S (May 2019). "SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity". Nature Immunology. 20 (5): 581–592. doi:10.1038/s41590-019-0372-7. hdl:10261/189024. PMID30962591. S2CID102353378.
Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM (November 2008). "Triggering the succinate receptor GPR91 on dendritic cells enhances immunity". Nature Immunology. 9 (11): 1261–9. doi:10.1038/ni.1657. PMID18820681. S2CID23526117.
Hakak Y, Lehmann-Bruinsma K, Phillips S, Le T, Liaw C, Connolly DT, Behan DP (May 2009). "The role of the GPR91 ligand succinate in hematopoiesis". Journal of Leukocyte Biology. 85 (5): 837–43. doi:10.1189/jlb.1008618. PMID19204147. S2CID2248388.
Pu M, Zhang J, Zeng Y, Hong F, Qi W, Yang X, Gao G, Zhou T (February 2023). "Succinate-SUCNR1 induces renal tubular cell apoptosis". American Journal of Physiology. Cell Physiology. 324 (2): C467–C476. doi:10.1152/ajpcell.00327.2022. PMID36622070. S2CID255544096.
Sell EA, Tan LH, Lin C, Bosso JV, Palmer JN, Adappa ND, Lee RJ, Kohanski MA, Reed DR, Cohen NA (August 2023). "Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium". International Forum of Allergy & Rhinology. 13 (8): 1525–1534. doi:10.1002/alr.23104. PMID36565436. S2CID255116741.
Du B, Jia X, Tian W, Yan X, Wang N, Cai D, Li X, Zhang H, Jin M, Wu N, Qiu C, Zhang Q (January 2021). "Associations of SUCNR1, GRK4, CAMK1D gene polymorphisms and the susceptibility of type 2 diabetes mellitus and essential hypertension in a northern Chinese Han population". Journal of Diabetes and Its Complications. 35 (1): 107752. doi:10.1016/j.jdiacomp.2020.107752. PMID33127268. S2CID225126632.
Li Q, Zhu Y, Wang J, Zhang Y, Pan Y, Gu R, Guo X, Wei L (February 2022). "Sedentary behaviors and gestational diabetes mellitus: A systematic review". The Journal of Obstetrics and Gynaecology Research. 48 (2): 285–299. doi:10.1111/jog.15090. PMID34750937. S2CID243863298.
Joyal JS, Omri S, Sitaras N, Rivera JC, Sapieha P, Chemtob S (August 2012). "Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A". Acta Paediatrica. 101 (8): 819–26. doi:10.1111/j.1651-2227.2012.02692.x. PMID22497252. S2CID38844477.
Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S (October 2008). "The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis". Nature Medicine. 14 (10): 1067–76. doi:10.1038/nm.1873. PMID18836459. S2CID6249205.
Rice JE, Vannucci RC, Brierley JB (February 1981). "The influence of immaturity on hypoxic-ischemic brain damage in the rat". Annals of Neurology. 9 (2): 131–41. doi:10.1002/ana.410090206. PMID7235629. S2CID34124161.
Shekher A, Puneet, Awasthee N, Kumar U, Raj R, Kumar D, Gupta SC (January 2023). "Association of altered metabolic profiles and long non-coding RNAs expression with disease severity in breast cancer patients: analysis by 1H NMR spectroscopy and RT-q-PCR". Metabolomics. 19 (2): 8. doi:10.1007/s11306-023-01972-5. PMID36710275. S2CID256362645.
Gravallese EM, Firestein GS (February 2023). "Rheumatoid Arthritis - Common Origins, Divergent Mechanisms". The New England Journal of Medicine. 388 (6): 529–542. doi:10.1056/NEJMra2103726. PMID36780677. S2CID256721972.