Semapimod (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Semapimod" in English language version.

refsWebsite

Global rank English rank

21nih.gov

4^th place

13doi.org

2^nd place

3semanticscholar.org

11^th place

8^th place

2harvard.edu

18^th place

17^th place

1jimmunol.org

low place

1jleukbio.org

low place

1psu.edu

207^th place

136^th place

doi.org

Bianchi M, Ulrich P, Bloom O, Meistrell M, Zimmerman GA, Schmidtmayerova H, et al. (March 1995). "An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality". Molecular Medicine. 1 (3): 254–66. doi:10.1007/BF03401550. PMC 2229913. PMID 8529104.
Bianchi M, Bloom O, Raabe T, Cohen PS, Chesney J, Sherry B, et al. (March 1996). "Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone". The Journal of Experimental Medicine. 183 (3): 927–36. doi:10.1084/jem.183.3.927. PMC 2192362. PMID 8642296.
Martiney JA, Rajan AJ, Charles PC, Cerami A, Ulrich PC, Macphail S, et al. (June 1998). "Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent" (Free full text). Journal of Immunology. 160 (11): 5588–95. doi:10.4049/jimmunol.160.11.5588. PMID 9605164. S2CID 12503616.
Hauber I, Bevec D, Heukeshoven J, Krätzer F, Horn F, Choidas A, et al. (January 2005). "Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy". The Journal of Clinical Investigation (Free full text). 115 (1): 76–85. doi:10.1172/JCI21949. PMC 539192. PMID 15630446.
Specht S, Sarite SR, Hauber I, Hauber J, Görbig UF, Meier C, et al. (May 2008). "The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase". Parasitology Research. 102 (6): 1177–84. doi:10.1007/s00436-008-0891-x. PMID 18256853. S2CID 27771876.
Cohen PS, Nakshatri H, Dennis J, Caragine T, Bianchi M, Cerami A, Tracey KJ (April 1996). "CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency". Proceedings of the National Academy of Sciences of the United States of America. 93 (9): 3967–71. Bibcode:1996PNAS...93.3967C. doi:10.1073/pnas.93.9.3967. PMC 39469. PMID 8632999.
Cohen PS, Schmidtmayerova H, Dennis J, Dubrovsky L, Sherry B, Wang H, et al. (May 1997). "The critical role of p38 MAP kinase in T cell HIV-1 replication". Molecular Medicine. 3 (5): 339–46. doi:10.1007/BF03401812. PMC 2230081. PMID 9205949.
Tracey KJ (February 2007). "Physiology and immunology of the cholinergic antiinflammatory pathway". The Journal of Clinical Investigation (Free full text). 117 (2): 289–96. doi:10.1172/JCI30555. PMC 1783813. PMID 17273548.
Oke SL, Tracey KJ (March 2008). "From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex" (Free full text). Journal of Leukocyte Biology. 83 (3): 512–7. CiteSeerX 10.1.1.527.419. doi:10.1189/jlb.0607363. PMID 18065685. S2CID 612157.
Kemeny MM, Botchkina GI, Ochani M, Bianchi M, Urmacher C, Tracey KJ (April 1998). "The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy". Proceedings of the National Academy of Sciences of the United States of America. 95 (8): 4561–6. Bibcode:1998PNAS...95.4561K. doi:10.1073/pnas.95.8.4561. PMC 22529. PMID 9539777.
Hommes D, van den Blink B, Plasse T, Bartelsman J, Xu C, Macpherson B, et al. (January 2002). "Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease". Gastroenterology. 122 (1): 7–14. doi:10.1053/gast.2002.30770. PMID 11781274.
van Westerloo DJ, Rauws EA, Hommes D, de Vos AF, van der Poll T, Powers BL, et al. (August 2008). "Pre-ERCP infusion of semapimod, a mitogen-activated protein kinases inhibitor, lowers post-ERCP hyperamylasemia but not pancreatitis incidence". Gastrointestinal Endoscopy. 68 (2): 246–54. doi:10.1016/j.gie.2008.01.034. PMID 18455169.
Ulrich P, Cerami A (January 1984). "Trypanocidal 1,3-arylene diketone bis(guanylhydrazone)s. Structure-activity relationships among substituted and heterocyclic analogues". Journal of Medicinal Chemistry. 27 (1): 35–40. doi:10.1021/jm00367a007. PMID 6690682.

harvard.edu

ui.adsabs.harvard.edu

Cohen PS, Nakshatri H, Dennis J, Caragine T, Bianchi M, Cerami A, Tracey KJ (April 1996). "CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency". Proceedings of the National Academy of Sciences of the United States of America. 93 (9): 3967–71. Bibcode:1996PNAS...93.3967C. doi:10.1073/pnas.93.9.3967. PMC 39469. PMID 8632999.
Kemeny MM, Botchkina GI, Ochani M, Bianchi M, Urmacher C, Tracey KJ (April 1998). "The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy". Proceedings of the National Academy of Sciences of the United States of America. 95 (8): 4561–6. Bibcode:1998PNAS...95.4561K. doi:10.1073/pnas.95.8.4561. PMC 22529. PMID 9539777.

jimmunol.org

Martiney JA, Rajan AJ, Charles PC, Cerami A, Ulrich PC, Macphail S, et al. (June 1998). "Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent" (Free full text). Journal of Immunology. 160 (11): 5588–95. doi:10.4049/jimmunol.160.11.5588. PMID 9605164. S2CID 12503616.

jleukbio.org

Oke SL, Tracey KJ (March 2008). "From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex" (Free full text). Journal of Leukocyte Biology. 83 (3): 512–7. CiteSeerX 10.1.1.527.419. doi:10.1189/jlb.0607363. PMID 18065685. S2CID 612157.

nih.gov

pubmed.ncbi.nlm.nih.gov

Bianchi M, Ulrich P, Bloom O, Meistrell M, Zimmerman GA, Schmidtmayerova H, et al. (March 1995). "An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality". Molecular Medicine. 1 (3): 254–66. doi:10.1007/BF03401550. PMC 2229913. PMID 8529104.
Bianchi M, Bloom O, Raabe T, Cohen PS, Chesney J, Sherry B, et al. (March 1996). "Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone". The Journal of Experimental Medicine. 183 (3): 927–36. doi:10.1084/jem.183.3.927. PMC 2192362. PMID 8642296.
Martiney JA, Rajan AJ, Charles PC, Cerami A, Ulrich PC, Macphail S, et al. (June 1998). "Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent" (Free full text). Journal of Immunology. 160 (11): 5588–95. doi:10.4049/jimmunol.160.11.5588. PMID 9605164. S2CID 12503616.
Hauber I, Bevec D, Heukeshoven J, Krätzer F, Horn F, Choidas A, et al. (January 2005). "Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy". The Journal of Clinical Investigation (Free full text). 115 (1): 76–85. doi:10.1172/JCI21949. PMC 539192. PMID 15630446.
Specht S, Sarite SR, Hauber I, Hauber J, Görbig UF, Meier C, et al. (May 2008). "The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase". Parasitology Research. 102 (6): 1177–84. doi:10.1007/s00436-008-0891-x. PMID 18256853. S2CID 27771876.
Cohen PS, Nakshatri H, Dennis J, Caragine T, Bianchi M, Cerami A, Tracey KJ (April 1996). "CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency". Proceedings of the National Academy of Sciences of the United States of America. 93 (9): 3967–71. Bibcode:1996PNAS...93.3967C. doi:10.1073/pnas.93.9.3967. PMC 39469. PMID 8632999.
Cohen PS, Schmidtmayerova H, Dennis J, Dubrovsky L, Sherry B, Wang H, et al. (May 1997). "The critical role of p38 MAP kinase in T cell HIV-1 replication". Molecular Medicine. 3 (5): 339–46. doi:10.1007/BF03401812. PMC 2230081. PMID 9205949.
Tracey KJ (February 2007). "Physiology and immunology of the cholinergic antiinflammatory pathway". The Journal of Clinical Investigation (Free full text). 117 (2): 289–96. doi:10.1172/JCI30555. PMC 1783813. PMID 17273548.
Oke SL, Tracey KJ (March 2008). "From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex" (Free full text). Journal of Leukocyte Biology. 83 (3): 512–7. CiteSeerX 10.1.1.527.419. doi:10.1189/jlb.0607363. PMID 18065685. S2CID 612157.
Kemeny MM, Botchkina GI, Ochani M, Bianchi M, Urmacher C, Tracey KJ (April 1998). "The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy". Proceedings of the National Academy of Sciences of the United States of America. 95 (8): 4561–6. Bibcode:1998PNAS...95.4561K. doi:10.1073/pnas.95.8.4561. PMC 22529. PMID 9539777.
Atkins MB, Redman B, Mier J, Gollob J, Weber J, Sosman J, et al. (March 2001). "A phase I study of CNI-1493, an inhibitor of cytokine release, in combination with high-dose interleukin-2 in patients with renal cancer and melanoma". Clinical Cancer Research. 7 (3): 486–92. PMID 11297238.
Hommes D, van den Blink B, Plasse T, Bartelsman J, Xu C, Macpherson B, et al. (January 2002). "Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease". Gastroenterology. 122 (1): 7–14. doi:10.1053/gast.2002.30770. PMID 11781274.
van Westerloo DJ, Rauws EA, Hommes D, de Vos AF, van der Poll T, Powers BL, et al. (August 2008). "Pre-ERCP infusion of semapimod, a mitogen-activated protein kinases inhibitor, lowers post-ERCP hyperamylasemia but not pancreatitis incidence". Gastrointestinal Endoscopy. 68 (2): 246–54. doi:10.1016/j.gie.2008.01.034. PMID 18455169.
Ulrich P, Cerami A (January 1984). "Trypanocidal 1,3-arylene diketone bis(guanylhydrazone)s. Structure-activity relationships among substituted and heterocyclic analogues". Journal of Medicinal Chemistry. 27 (1): 35–40. doi:10.1021/jm00367a007. PMID 6690682.

ncbi.nlm.nih.gov

Bianchi M, Ulrich P, Bloom O, Meistrell M, Zimmerman GA, Schmidtmayerova H, et al. (March 1995). "An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality". Molecular Medicine. 1 (3): 254–66. doi:10.1007/BF03401550. PMC 2229913. PMID 8529104.
Bianchi M, Bloom O, Raabe T, Cohen PS, Chesney J, Sherry B, et al. (March 1996). "Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone". The Journal of Experimental Medicine. 183 (3): 927–36. doi:10.1084/jem.183.3.927. PMC 2192362. PMID 8642296.
Hauber I, Bevec D, Heukeshoven J, Krätzer F, Horn F, Choidas A, et al. (January 2005). "Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy". The Journal of Clinical Investigation (Free full text). 115 (1): 76–85. doi:10.1172/JCI21949. PMC 539192. PMID 15630446.
Cohen PS, Nakshatri H, Dennis J, Caragine T, Bianchi M, Cerami A, Tracey KJ (April 1996). "CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency". Proceedings of the National Academy of Sciences of the United States of America. 93 (9): 3967–71. Bibcode:1996PNAS...93.3967C. doi:10.1073/pnas.93.9.3967. PMC 39469. PMID 8632999.
Cohen PS, Schmidtmayerova H, Dennis J, Dubrovsky L, Sherry B, Wang H, et al. (May 1997). "The critical role of p38 MAP kinase in T cell HIV-1 replication". Molecular Medicine. 3 (5): 339–46. doi:10.1007/BF03401812. PMC 2230081. PMID 9205949.
Tracey KJ (February 2007). "Physiology and immunology of the cholinergic antiinflammatory pathway". The Journal of Clinical Investigation (Free full text). 117 (2): 289–96. doi:10.1172/JCI30555. PMC 1783813. PMID 17273548.
Kemeny MM, Botchkina GI, Ochani M, Bianchi M, Urmacher C, Tracey KJ (April 1998). "The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy". Proceedings of the National Academy of Sciences of the United States of America. 95 (8): 4561–6. Bibcode:1998PNAS...95.4561K. doi:10.1073/pnas.95.8.4561. PMC 22529. PMID 9539777.

psu.edu

citeseerx.ist.psu.edu

Oke SL, Tracey KJ (March 2008). "From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex" (Free full text). Journal of Leukocyte Biology. 83 (3): 512–7. CiteSeerX 10.1.1.527.419. doi:10.1189/jlb.0607363. PMID 18065685. S2CID 612157.

semanticscholar.org

api.semanticscholar.org

Martiney JA, Rajan AJ, Charles PC, Cerami A, Ulrich PC, Macphail S, et al. (June 1998). "Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent" (Free full text). Journal of Immunology. 160 (11): 5588–95. doi:10.4049/jimmunol.160.11.5588. PMID 9605164. S2CID 12503616.
Specht S, Sarite SR, Hauber I, Hauber J, Görbig UF, Meier C, et al. (May 2008). "The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase". Parasitology Research. 102 (6): 1177–84. doi:10.1007/s00436-008-0891-x. PMID 18256853. S2CID 27771876.
Oke SL, Tracey KJ (March 2008). "From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex" (Free full text). Journal of Leukocyte Biology. 83 (3): 512–7. CiteSeerX 10.1.1.527.419. doi:10.1189/jlb.0607363. PMID 18065685. S2CID 612157.