Stem cell theory of aging (English Wikipedia)

Wallenfang MR, Nayak R, DiNardo S (2006). "Dynamics of the male germline stem cell population during aging of Drosophila melanogaster". Aging Cell. 5 (4): 297–304. doi:10.1111/j.1474-9726.2006.00221.x. PMID 16800845. S2CID 23514768.
Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas M, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Luscher T, Pelicci P, Anversa P, Leri A, Kajstura J (2006). "Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene". Circ. Res. 99 (1): 42–52. doi:10.1161/01.RES.0000231289.63468.08. PMID 16763167.
Bodmer F, Crouch DJ (2020). "Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing". Journal of Theoretical Biology. 489: 110153. Bibcode:2020JThBi.48910153B. doi:10.1016/j.jtbi.2020.110153. PMID 31935413. S2CID 210814272.
Behrens A, van Deursen JM, Rudolph KL, Schumacher B (2014). "Impact of genomic damage and ageing on stem cell function". Nat. Cell Biol. 16 (3): 201–7. doi:10.1038/ncb2928. PMC 4214082. PMID 24576896.
Mahla RS (2016). "Stem cells application in regenerative medicine and disease threpeutics". International Journal of Cell Biology. 2016 (7): 19. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (2007). "Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age". Nature. 447 (7145): 725–9. Bibcode:2007Natur.447..725R. doi:10.1038/nature05862. PMID 17554309. S2CID 4416445.
Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ (2014). "Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle". Cell Stem Cell. 15 (1): 37–50. doi:10.1016/j.stem.2014.04.016. PMC 4082747. PMID 24813857.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ (2007). "DNA repair is limiting for haematopoietic stem cells during ageing". Nature. 447 (7145): 686–90. Bibcode:2007Natur.447..686N. doi:10.1038/nature05875. PMID 17554302. S2CID 4332976.
Mitchell, Emily; Spencer Chapman, Michael; Williams, Nicholas; Dawson, Kevin J.; Mende, Nicole; Calderbank, Emily F.; Jung, Hyunchul; Mitchell, Thomas; Coorens, Tim H. H.; Spencer, David H.; Machado, Heather; Lee-Six, Henry; Davies, Megan; Hayler, Daniel; Fabre, Margarete A.; Mahbubani, Krishnaa; Abascal, Federico; Cagan, Alex; Vassiliou, George S.; Baxter, Joanna; Martincorena, Inigo; Stratton, Michael R.; Kent, David G.; Chatterjee, Krishna; Parsy, Kourosh Saeb; Green, Anthony R.; Nangalia, Jyoti; Laurenti, Elisa; Campbell, Peter J. (June 2022). "Clonal dynamics of haematopoiesis across the human lifespan". Nature. 606 (7913): 343–350. Bibcode:2022Natur.606..343M. doi:10.1038/s41586-022-04786-y. ISSN 1476-4687. PMC 9177428. PMID 35650442.
Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan; Chavkin, Nicholas W.; Wang, Ying; Sano, Miho; Mattisson, Jonas; Hata, Atsushi; Danielsson, Marcus; Miura-Yura, Emiri; Zaghlool, Ammar; Evans, Megan A.; Fall, Tove; De Hoyos, Henry N.; Sundström, Johan; Yura, Yoshimitsu; Kour, Anupreet; Arai, Yohei; Thel, Mark C.; Arai, Yuka; Mychaleckyj, Josyf C.; Hirschi, Karen K.; Forsberg, Lars A.; Walsh, Kenneth (15 July 2022). "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality". Science. 377 (6603): 292–297. Bibcode:2022Sci...377..292S. doi:10.1126/science.abn3100. ISSN 0036-8075. PMC 9437978. PMID 35857592.
Lei M, Chuong CM (2016). "STEM CELLS. Aging, alopecia, and stem cells". Science. 351 (6273): 559–60. Bibcode:2016Sci...351..559L. doi:10.1126/science.aaf1635. PMID 26912687.
Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK (2016). "Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis". Science. 351 (6273): aad4395. doi:10.1126/science.aad4395. PMID 26912707. S2CID 5078019.
Liang Y, Zant G (2008). "Aging stem cells, latexin, and longevity". Experimental Cell Research. 314 (9): 1962–1972. doi:10.1016/j.yexcr.2008.01.032. PMC 2471873. PMID 18374916.

harvard.edu

ui.adsabs.harvard.edu

Bodmer F, Crouch DJ (2020). "Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing". Journal of Theoretical Biology. 489: 110153. Bibcode:2020JThBi.48910153B. doi:10.1016/j.jtbi.2020.110153. PMID 31935413. S2CID 210814272.
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (2007). "Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age". Nature. 447 (7145): 725–9. Bibcode:2007Natur.447..725R. doi:10.1038/nature05862. PMID 17554309. S2CID 4416445.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ (2007). "DNA repair is limiting for haematopoietic stem cells during ageing". Nature. 447 (7145): 686–90. Bibcode:2007Natur.447..686N. doi:10.1038/nature05875. PMID 17554302. S2CID 4332976.
Mitchell, Emily; Spencer Chapman, Michael; Williams, Nicholas; Dawson, Kevin J.; Mende, Nicole; Calderbank, Emily F.; Jung, Hyunchul; Mitchell, Thomas; Coorens, Tim H. H.; Spencer, David H.; Machado, Heather; Lee-Six, Henry; Davies, Megan; Hayler, Daniel; Fabre, Margarete A.; Mahbubani, Krishnaa; Abascal, Federico; Cagan, Alex; Vassiliou, George S.; Baxter, Joanna; Martincorena, Inigo; Stratton, Michael R.; Kent, David G.; Chatterjee, Krishna; Parsy, Kourosh Saeb; Green, Anthony R.; Nangalia, Jyoti; Laurenti, Elisa; Campbell, Peter J. (June 2022). "Clonal dynamics of haematopoiesis across the human lifespan". Nature. 606 (7913): 343–350. Bibcode:2022Natur.606..343M. doi:10.1038/s41586-022-04786-y. ISSN 1476-4687. PMC 9177428. PMID 35650442.
Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan; Chavkin, Nicholas W.; Wang, Ying; Sano, Miho; Mattisson, Jonas; Hata, Atsushi; Danielsson, Marcus; Miura-Yura, Emiri; Zaghlool, Ammar; Evans, Megan A.; Fall, Tove; De Hoyos, Henry N.; Sundström, Johan; Yura, Yoshimitsu; Kour, Anupreet; Arai, Yohei; Thel, Mark C.; Arai, Yuka; Mychaleckyj, Josyf C.; Hirschi, Karen K.; Forsberg, Lars A.; Walsh, Kenneth (15 July 2022). "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality". Science. 377 (6603): 292–297. Bibcode:2022Sci...377..292S. doi:10.1126/science.abn3100. ISSN 0036-8075. PMC 9437978. PMID 35857592.
Lei M, Chuong CM (2016). "STEM CELLS. Aging, alopecia, and stem cells". Science. 351 (6273): 559–60. Bibcode:2016Sci...351..559L. doi:10.1126/science.aaf1635. PMID 26912687.

nih.gov

pubmed.ncbi.nlm.nih.gov

Wallenfang MR, Nayak R, DiNardo S (2006). "Dynamics of the male germline stem cell population during aging of Drosophila melanogaster". Aging Cell. 5 (4): 297–304. doi:10.1111/j.1474-9726.2006.00221.x. PMID 16800845. S2CID 23514768.
Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas M, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Luscher T, Pelicci P, Anversa P, Leri A, Kajstura J (2006). "Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene". Circ. Res. 99 (1): 42–52. doi:10.1161/01.RES.0000231289.63468.08. PMID 16763167.
Bodmer F, Crouch DJ (2020). "Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing". Journal of Theoretical Biology. 489: 110153. Bibcode:2020JThBi.48910153B. doi:10.1016/j.jtbi.2020.110153. PMID 31935413. S2CID 210814272.
Behrens A, van Deursen JM, Rudolph KL, Schumacher B (2014). "Impact of genomic damage and ageing on stem cell function". Nat. Cell Biol. 16 (3): 201–7. doi:10.1038/ncb2928. PMC 4214082. PMID 24576896.
Mahla RS (2016). "Stem cells application in regenerative medicine and disease threpeutics". International Journal of Cell Biology. 2016 (7): 19. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (2007). "Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age". Nature. 447 (7145): 725–9. Bibcode:2007Natur.447..725R. doi:10.1038/nature05862. PMID 17554309. S2CID 4416445.
Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ (2014). "Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle". Cell Stem Cell. 15 (1): 37–50. doi:10.1016/j.stem.2014.04.016. PMC 4082747. PMID 24813857.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ (2007). "DNA repair is limiting for haematopoietic stem cells during ageing". Nature. 447 (7145): 686–90. Bibcode:2007Natur.447..686N. doi:10.1038/nature05875. PMID 17554302. S2CID 4332976.
Mitchell, Emily; Spencer Chapman, Michael; Williams, Nicholas; Dawson, Kevin J.; Mende, Nicole; Calderbank, Emily F.; Jung, Hyunchul; Mitchell, Thomas; Coorens, Tim H. H.; Spencer, David H.; Machado, Heather; Lee-Six, Henry; Davies, Megan; Hayler, Daniel; Fabre, Margarete A.; Mahbubani, Krishnaa; Abascal, Federico; Cagan, Alex; Vassiliou, George S.; Baxter, Joanna; Martincorena, Inigo; Stratton, Michael R.; Kent, David G.; Chatterjee, Krishna; Parsy, Kourosh Saeb; Green, Anthony R.; Nangalia, Jyoti; Laurenti, Elisa; Campbell, Peter J. (June 2022). "Clonal dynamics of haematopoiesis across the human lifespan". Nature. 606 (7913): 343–350. Bibcode:2022Natur.606..343M. doi:10.1038/s41586-022-04786-y. ISSN 1476-4687. PMC 9177428. PMID 35650442.
Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan; Chavkin, Nicholas W.; Wang, Ying; Sano, Miho; Mattisson, Jonas; Hata, Atsushi; Danielsson, Marcus; Miura-Yura, Emiri; Zaghlool, Ammar; Evans, Megan A.; Fall, Tove; De Hoyos, Henry N.; Sundström, Johan; Yura, Yoshimitsu; Kour, Anupreet; Arai, Yohei; Thel, Mark C.; Arai, Yuka; Mychaleckyj, Josyf C.; Hirschi, Karen K.; Forsberg, Lars A.; Walsh, Kenneth (15 July 2022). "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality". Science. 377 (6603): 292–297. Bibcode:2022Sci...377..292S. doi:10.1126/science.abn3100. ISSN 0036-8075. PMC 9437978. PMID 35857592.
Lei M, Chuong CM (2016). "STEM CELLS. Aging, alopecia, and stem cells". Science. 351 (6273): 559–60. Bibcode:2016Sci...351..559L. doi:10.1126/science.aaf1635. PMID 26912687.
Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK (2016). "Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis". Science. 351 (6273): aad4395. doi:10.1126/science.aad4395. PMID 26912707. S2CID 5078019.
Liang Y, Zant G (2008). "Aging stem cells, latexin, and longevity". Experimental Cell Research. 314 (9): 1962–1972. doi:10.1016/j.yexcr.2008.01.032. PMC 2471873. PMID 18374916.

ncbi.nlm.nih.gov

Behrens A, van Deursen JM, Rudolph KL, Schumacher B (2014). "Impact of genomic damage and ageing on stem cell function". Nat. Cell Biol. 16 (3): 201–7. doi:10.1038/ncb2928. PMC 4214082. PMID 24576896.
Mahla RS (2016). "Stem cells application in regenerative medicine and disease threpeutics". International Journal of Cell Biology. 2016 (7): 19. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.
Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ (2014). "Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle". Cell Stem Cell. 15 (1): 37–50. doi:10.1016/j.stem.2014.04.016. PMC 4082747. PMID 24813857.
Mitchell, Emily; Spencer Chapman, Michael; Williams, Nicholas; Dawson, Kevin J.; Mende, Nicole; Calderbank, Emily F.; Jung, Hyunchul; Mitchell, Thomas; Coorens, Tim H. H.; Spencer, David H.; Machado, Heather; Lee-Six, Henry; Davies, Megan; Hayler, Daniel; Fabre, Margarete A.; Mahbubani, Krishnaa; Abascal, Federico; Cagan, Alex; Vassiliou, George S.; Baxter, Joanna; Martincorena, Inigo; Stratton, Michael R.; Kent, David G.; Chatterjee, Krishna; Parsy, Kourosh Saeb; Green, Anthony R.; Nangalia, Jyoti; Laurenti, Elisa; Campbell, Peter J. (June 2022). "Clonal dynamics of haematopoiesis across the human lifespan". Nature. 606 (7913): 343–350. Bibcode:2022Natur.606..343M. doi:10.1038/s41586-022-04786-y. ISSN 1476-4687. PMC 9177428. PMID 35650442.
Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan; Chavkin, Nicholas W.; Wang, Ying; Sano, Miho; Mattisson, Jonas; Hata, Atsushi; Danielsson, Marcus; Miura-Yura, Emiri; Zaghlool, Ammar; Evans, Megan A.; Fall, Tove; De Hoyos, Henry N.; Sundström, Johan; Yura, Yoshimitsu; Kour, Anupreet; Arai, Yohei; Thel, Mark C.; Arai, Yuka; Mychaleckyj, Josyf C.; Hirschi, Karen K.; Forsberg, Lars A.; Walsh, Kenneth (15 July 2022). "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality". Science. 377 (6603): 292–297. Bibcode:2022Sci...377..292S. doi:10.1126/science.abn3100. ISSN 0036-8075. PMC 9437978. PMID 35857592.
Liang Y, Zant G (2008). "Aging stem cells, latexin, and longevity". Experimental Cell Research. 314 (9): 1962–1972. doi:10.1016/j.yexcr.2008.01.032. PMC 2471873. PMID 18374916.

nhlbi.nih.gov

"Aplastic Anemia | NHLBI, NIH". Nhlbi.nih.gov. 18 January 2019. Retrieved 19 February 2022.

nytimes.com

Kolata, Gina (14 July 2022). "As Y Chromosomes Vanish With Age, Heart Risks May Grow". The New York Times. Retrieved 21 August 2022.

sciencedirect.com

Bodmer F, Crouch DJ (2020). "Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing". Journal of Theoretical Biology. 489: 110153. Bibcode:2020JThBi.48910153B. doi:10.1016/j.jtbi.2020.110153. PMID 31935413. S2CID 210814272.

semanticscholar.org

api.semanticscholar.org

Wallenfang MR, Nayak R, DiNardo S (2006). "Dynamics of the male germline stem cell population during aging of Drosophila melanogaster". Aging Cell. 5 (4): 297–304. doi:10.1111/j.1474-9726.2006.00221.x. PMID 16800845. S2CID 23514768.
Bodmer F, Crouch DJ (2020). "Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing". Journal of Theoretical Biology. 489: 110153. Bibcode:2020JThBi.48910153B. doi:10.1016/j.jtbi.2020.110153. PMID 31935413. S2CID 210814272.
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (2007). "Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age". Nature. 447 (7145): 725–9. Bibcode:2007Natur.447..725R. doi:10.1038/nature05862. PMID 17554309. S2CID 4416445.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ (2007). "DNA repair is limiting for haematopoietic stem cells during ageing". Nature. 447 (7145): 686–90. Bibcode:2007Natur.447..686N. doi:10.1038/nature05875. PMID 17554302. S2CID 4332976.
Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK (2016). "Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis". Science. 351 (6273): aad4395. doi:10.1126/science.aad4395. PMID 26912707. S2CID 5078019.

theguardian.com

"Research may reveal why people can suddenly become frail in their 70s". The Guardian. 1 June 2022. Retrieved 18 July 2022.

web.archive.org

"Bone Marrow in Aging: Changes? Yes; Clinical Malfunction? Not So Clear". Archived from the original on 9 December 2018.

worldcat.org

search.worldcat.org

Mitchell, Emily; Spencer Chapman, Michael; Williams, Nicholas; Dawson, Kevin J.; Mende, Nicole; Calderbank, Emily F.; Jung, Hyunchul; Mitchell, Thomas; Coorens, Tim H. H.; Spencer, David H.; Machado, Heather; Lee-Six, Henry; Davies, Megan; Hayler, Daniel; Fabre, Margarete A.; Mahbubani, Krishnaa; Abascal, Federico; Cagan, Alex; Vassiliou, George S.; Baxter, Joanna; Martincorena, Inigo; Stratton, Michael R.; Kent, David G.; Chatterjee, Krishna; Parsy, Kourosh Saeb; Green, Anthony R.; Nangalia, Jyoti; Laurenti, Elisa; Campbell, Peter J. (June 2022). "Clonal dynamics of haematopoiesis across the human lifespan". Nature. 606 (7913): 343–350. Bibcode:2022Natur.606..343M. doi:10.1038/s41586-022-04786-y. ISSN 1476-4687. PMC 9177428. PMID 35650442.
Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan; Chavkin, Nicholas W.; Wang, Ying; Sano, Miho; Mattisson, Jonas; Hata, Atsushi; Danielsson, Marcus; Miura-Yura, Emiri; Zaghlool, Ammar; Evans, Megan A.; Fall, Tove; De Hoyos, Henry N.; Sundström, Johan; Yura, Yoshimitsu; Kour, Anupreet; Arai, Yohei; Thel, Mark C.; Arai, Yuka; Mychaleckyj, Josyf C.; Hirschi, Karen K.; Forsberg, Lars A.; Walsh, Kenneth (15 July 2022). "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality". Science. 377 (6603): 292–297. Bibcode:2022Sci...377..292S. doi:10.1126/science.abn3100. ISSN 0036-8075. PMC 9437978. PMID 35857592.