Trospium chloride (English Wikipedia)

US 6974820 which cites US 3480626 and Bertholdt H, Pfleger R, Schulz W (1967). "[On azoniaspire-compounds. 2. Preparation of esterified azoniaspire-compounds of nortropan-3-alpha- or 3-beta-ol (1)]". Arzneimittelforschung. 17 (6): 719–26. PMID 5632538.

doi.org

Biastre K, Burnakis T (February 2009). "Trospium chloride treatment of overactive bladder". Ann Pharmacother. 43 (2): 283–95. doi:10.1345/aph.1L160. PMID 19193592. S2CID 20102756.
Pak RW, Petrou SP, Staskin DR (December 2003). "Trospium chloride : a quaternary amine with unique pharmacologic properties". Curr Urol Rep. 4 (6): 436–40. doi:10.1007/s11934-003-0023-1. PMID 14622495. S2CID 4512769.
Liu T (2020). "BindingDB BDBM50540489 Flotros::IP-631::IP631::Regurin::Regurin xl::Sanctura::Sanctura xr::Spasmo-lyt::Trospium chloride::Uraplex". Journal of Medicinal Chemistry. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602. Retrieved 28 October 2024.
Del Bello F, Bonifazi A, Giorgioni G, Piergentili A, Sabbieti MG, Agas D, et al. (June 2020). "Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus". J Med Chem. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602.
Peretto I, Petrillo P, Imbimbo BP (November 2009). "Medicinal chemistry and therapeutic potential of muscarinic M3 antagonists". Med Res Rev. 29 (6): 867–902. doi:10.1002/med.20158. PMID 19399831.
Pak RW, Petrou SP, Staskin DR (December 2003). "Trospium chloride: a quaternary amine with unique pharmacologic properties". Curr Urol Rep. 4 (6): 436–440. doi:10.1007/s11934-003-0023-1. PMID 14622495.
Rosa GM, Bauckneht M, Scala C, Tafi E, Leone Roberti Maggiore U, Ferrero S, et al. (November 2013). "Cardiovascular effects of antimuscarinic agents in overactive bladder". Expert Opin Drug Saf. 12 (6): 815–827. doi:10.1517/14740338.2013.813016. PMID 23800037.
Doroshyenko O, Jetter A, Odenthal KP, Fuhr U (2005). "Clinical pharmacokinetics of trospium chloride". Clin Pharmacokinet. 44 (7): 701–20. doi:10.2165/00003088-200544070-00003. PMID 15966754. S2CID 10968270.

drugs.com

"International brands of trospium". Drugs.com. Retrieved 13 May 2016.

espacenet.com

worldwide.espacenet.com

DE patent 1194422, Bertholdt H, Pfleger R, Schulz W, "[Verfahren zur Herstellung von Azoniaspironortropanderivaten] (A process for preparing azonia-spirono-tropane derivatives)", issued 10 June 1965, assigned to Dr. Robert Pfleger Chemische Fabrik GmbH

evaluategroup.com

"Indevus and PLIVA Sign Co-Promotion and Licensing Agreement for SANCTURA -Trospium Chloride". Indevus Press Release. 7 April 2004. Archived from the original on 27 August 2021. Retrieved 14 May 2016.

fda.gov

accessdata.fda.gov

FDA "Trospium chloride label" (PDF). U.S. Food and Drug Administration. January 2011.
"ANDA 091289 approval letter" (PDF). U.S. Food and Drug Administration. 12 October 2012.

firstwordpharma.com

Osterweil N (28 May 2004). "FDA approves Indevus' Sanctura". for First Word Pharma.

forbes.com

Herper M (25 September 2002). "A Biotech Phoenix Could Be Rising". Forbes.

lexology.com

"Court takes a permissive approach to parallel importers within the EU". Lexology. 6 March 2015.

medicines.org.uk

"Regurin XL 60mg". UK eMC. 3 July 2015.

mhra.gov.uk

"Trospium Chloride 20mg Film-Coated Tablets, Public Assessment Report" (PDF). Medicines and Healthcare products Regulatory Agency. 7 April 2011.

modernmedicine.com

urologytimes.modernmedicine.com

"Novartis, P&G enter agreement for OAB drug". Urology Times. 21 July 2005.

nih.gov

pubmed.ncbi.nlm.nih.gov

Biastre K, Burnakis T (February 2009). "Trospium chloride treatment of overactive bladder". Ann Pharmacother. 43 (2): 283–95. doi:10.1345/aph.1L160. PMID 19193592. S2CID 20102756.
Pak RW, Petrou SP, Staskin DR (December 2003). "Trospium chloride : a quaternary amine with unique pharmacologic properties". Curr Urol Rep. 4 (6): 436–40. doi:10.1007/s11934-003-0023-1. PMID 14622495. S2CID 4512769.
Liu T (2020). "BindingDB BDBM50540489 Flotros::IP-631::IP631::Regurin::Regurin xl::Sanctura::Sanctura xr::Spasmo-lyt::Trospium chloride::Uraplex". Journal of Medicinal Chemistry. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602. Retrieved 28 October 2024.
Del Bello F, Bonifazi A, Giorgioni G, Piergentili A, Sabbieti MG, Agas D, et al. (June 2020). "Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus". J Med Chem. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602.
Peretto I, Petrillo P, Imbimbo BP (November 2009). "Medicinal chemistry and therapeutic potential of muscarinic M3 antagonists". Med Res Rev. 29 (6): 867–902. doi:10.1002/med.20158. PMID 19399831.
Pak RW, Petrou SP, Staskin DR (December 2003). "Trospium chloride: a quaternary amine with unique pharmacologic properties". Curr Urol Rep. 4 (6): 436–440. doi:10.1007/s11934-003-0023-1. PMID 14622495.
Rosa GM, Bauckneht M, Scala C, Tafi E, Leone Roberti Maggiore U, Ferrero S, et al. (November 2013). "Cardiovascular effects of antimuscarinic agents in overactive bladder". Expert Opin Drug Saf. 12 (6): 815–827. doi:10.1517/14740338.2013.813016. PMID 23800037.
Doroshyenko O, Jetter A, Odenthal KP, Fuhr U (2005). "Clinical pharmacokinetics of trospium chloride". Clin Pharmacokinet. 44 (7): 701–20. doi:10.2165/00003088-200544070-00003. PMID 15966754. S2CID 10968270.
US 6974820 which cites US 3480626 and Bertholdt H, Pfleger R, Schulz W (1967). "[On azoniaspire-compounds. 2. Preparation of esterified azoniaspire-compounds of nortropan-3-alpha- or 3-beta-ol (1)]". Arzneimittelforschung. 17 (6): 719–26. PMID 5632538.

ncbi.nlm.nih.gov

Liu T (2020). "BindingDB BDBM50540489 Flotros::IP-631::IP631::Regurin::Regurin xl::Sanctura::Sanctura xr::Spasmo-lyt::Trospium chloride::Uraplex". Journal of Medicinal Chemistry. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602. Retrieved 28 October 2024.
Del Bello F, Bonifazi A, Giorgioni G, Piergentili A, Sabbieti MG, Agas D, et al. (June 2020). "Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus". J Med Chem. 63 (11): 5763–5782. doi:10.1021/acs.jmedchem.9b02100. PMC 8007111. PMID 32374602.

prnewswire.com

"Watson's Generic Sanctura XR Receives FDA Approval". Watson Press Release. 12 October 2012.

sec.gov

"Indevus Pharmaceuticals, Inc., Formerly Interneuron, to Begin Trading on Nasdaq". Indevus Press Release. 2 April 2002.
"Indevus Announces FDA Approval Of Sanctura". Indevus Press Release. 28 May 2004.
"Indevus Announces Allergan as New Partner for Sanctura Brand". Indevus Press Release. 19 September 2007.

semanticscholar.org

api.semanticscholar.org

Biastre K, Burnakis T (February 2009). "Trospium chloride treatment of overactive bladder". Ann Pharmacother. 43 (2): 283–95. doi:10.1345/aph.1L160. PMID 19193592. S2CID 20102756.
Pak RW, Petrou SP, Staskin DR (December 2003). "Trospium chloride : a quaternary amine with unique pharmacologic properties". Curr Urol Rep. 4 (6): 436–40. doi:10.1007/s11934-003-0023-1. PMID 14622495. S2CID 4512769.
Doroshyenko O, Jetter A, Odenthal KP, Fuhr U (2005). "Clinical pharmacokinetics of trospium chloride". Clin Pharmacokinet. 44 (7): 701–20. doi:10.2165/00003088-200544070-00003. PMID 15966754. S2CID 10968270.

springer.com

adisinsight.springer.com

"Trospium chloride". AdisInsight. Springer Nature Switzerland AG.

thepharmaletter.com

"Indevus' Sanctura XR approved by US FDA". The Pharma Letter. 13 August 2007.

upi.com

"Alkermes, Indevus testing COPD drug". UPI. 25 April 2007.

web.archive.org

"Indevus and PLIVA Sign Co-Promotion and Licensing Agreement for SANCTURA -Trospium Chloride". Indevus Press Release. 7 April 2004. Archived from the original on 27 August 2021. Retrieved 14 May 2016.