Vortioxetine (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Vortioxetine" in English language version.

refsWebsite

Global rank English rank

52nih.gov

4^th place

39doi.org

2^nd place

17semanticscholar.org

11^th place

8^th place

7web.archive.org

1^st place

6tga.gov.au

3,984^th place

2,622^nd place

3fda.gov

447^th place

338^th place

2europa.eu

68^th place

117^th place

2clincalc.com

3,912^th place

2,496^th place

1webmd.com

1,169^th place

1,075^th place

1in.gov.br

3,151^st place

5,932^nd place

1canada.ca

1,712^th place

1,063^rd place

1medicines.org.uk

3,823^rd place

2,387^th place

1drugs.com

399^th place

333^rd place

1handle.net

102^nd place

76^th place

1glgroup.com

low place

1firstwordpharma.com

low place

1springer.com

274^th place

309^th place

canada.ca

"Product monograph brand safety updates". Health Canada. 6 June 2024. Retrieved 8 June 2024.

clincalc.com

"The Top 300 of 2020". ClinCalc. Retrieved 7 October 2022.
"Vortioxetine - Drug Usage Statistics". ClinCalc. Retrieved 7 October 2022.

doi.org

Chen G, Højer AM, Areberg J, Nomikos G (June 2018). "Vortioxetine: Clinical Pharmacokinetics and Drug Interactions". Clinical Pharmacokinetics. 57 (6): 673–686. doi:10.1007/s40262-017-0612-7. PMC 5973995. PMID 29189941.
Bundgaard C, Pehrson AL, Sánchez C, Bang-Andersen B (2 January 2015). "Case Study 2". Blood-Brain Barrier in Drug Discovery. Hoboken, NJ: John Wiley & Sons, Inc. pp. 505–520. doi:10.1002/9781118788523.ch23. ISBN 9781118788523.
Keks NA, Hope J, Culhane C (June 2015). "Vortioxetine: A multimodal antidepressant or another selective serotonin reuptake inhibitor?". Australas Psychiatry. 23 (3): 210–3. doi:10.1177/1039856215581297. PMID 25907797. S2CID 21642202.
Zhang J, Mathis MV, Sellers JW, Kordzakhia G, Jackson AJ, Dow A, Yang P, Fossom L, Zhu H, Patel H, Unger EF, Temple RJ (January 2015). "The US Food and Drug Administration's perspective on the new antidepressant vortioxetine". J Clin Psychiatry. 76 (1): 8–14. doi:10.4088/JCP.14r09164. PMID 25562777.
Gibb A, Deeks ED (January 2014). "Vortioxetine: first global approval". Drugs. 74 (1): 135–145. doi:10.1007/s40265-013-0161-9. PMID 24311349. S2CID 5987668.
Long JD (September 2019). "Vortioxetine for Depression in Adults". Issues in Mental Health Nursing. 40 (9). Informa UK Limited: 819–820. doi:10.1080/01612840.2019.1604920. PMID 31225773. S2CID 195192772.
Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JP, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JP, Geddes JR (April 2018). "Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis". Lancet. 391 (10128): 1357–1366. doi:10.1016/S0140-6736(17)32802-7. PMC 5889788. PMID 29477251.
Sowa-Kućma M, Pańczyszyn-Trzewik P, Misztak P, Jaeschke RR, Sendek K, Styczeń K, Datka W, Koperny M (August 2017). "Vortioxetine: A review of the pharmacology and clinical profile of the novel antidepressant". Pharmacol Rep. 69 (4): 595–601. doi:10.1016/j.pharep.2017.01.030. PMID 28499187. S2CID 43104089.
Connolly KR, Thase ME (2016). "Vortioxetine: a New Treatment for Major Depressive Disorder". Expert Opinion on Pharmacotherapy. 17 (3): 421–31. doi:10.1517/14656566.2016.1133588. PMID 26679430. S2CID 40432194. The authors suggest that vortioxetine is currently a good second-line antidepressant option and shows promise, pending additional long-term data, to become a first-line antidepressant option.
Köhler S, Cierpinsky K, Kronenberg G, Adli M (January 2016). "The serotonergic system in the neurobiology of depression: Relevance for novel antidepressants". Journal of Psychopharmacology. 30 (1): 13–22. doi:10.1177/0269881115609072. PMID 26464458. S2CID 21501578.
Kelliny M, Croarkin PE, Moore KM, Bobo WV (2015). "Profile of vortioxetine in the treatment of major depressive disorder: an overview of the primary and secondary literature". Therapeutics and Clinical Risk Management. 11: 1193–212. doi:10.2147/TCRM.S55313. PMC 4542474. PMID 26316764.
Koesters M, Ostuzzi G, Guaiana G, Breilmann J, Barbui C (July 2017). "Vortioxetine for depression in adults". The Cochrane Database of Systematic Reviews. 2017 (7): CD011520. doi:10.1002/14651858.CD011520.pub2. PMC 6483322. PMID 28677828.
Mattingly GW, Ren H, Christensen MC, Katzman MA, Polosan M, Simonsen K, Hammer-Helmich L (2022). "Effectiveness of Vortioxetine in Patients With Major Depressive Disorder in Real-World Clinical Practice: Results of the RELIEVE Study". Frontiers in Psychiatry. 13: 824831. doi:10.3389/fpsyt.2022.824831. PMC 8959350. PMID 35356713.
Pae CU, Wang SM, Han C, Lee SJ, Patkar AA, Masand PS, Serretti A (May 2015). "Vortioxetine, a multimodal antidepressant for generalized anxiety disorder: a systematic review and meta-analysis". Journal of Psychiatric Research. 64: 88–98. doi:10.1016/j.jpsychires.2015.02.017. PMID 25851751.
Fu J, Peng L, Li X (19 April 2016). "The efficacy and safety of multiple doses of vortioxetine for generalized anxiety disorder: a meta-analysis". Neuropsychiatric Disease and Treatment. 12: 951–9. doi:10.2147/NDT.S104050. PMC 4844447. PMID 27143896.
Qin B, Huang G, Yang Q, Zhao M, Chen H, Gao W, Yang M (November 2019). "Vortioxetine treatment for generalised anxiety disorder: a meta-analysis of anxiety, quality of life and safety outcomes". BMJ Open. 9 (11): e033161. doi:10.1136/bmjopen-2019-033161. PMC 6924794. PMID 31784448.
Yee A, Ng CG, Seng LH (2018). "Vortioxetine Treatment for Anxiety Disorder: A Meta-Analysis Study". Current Drug Targets. 19 (12): 1412–1423. doi:10.2174/1389450118666171117131151. PMID 29149828. S2CID 11855728.
Meza N, Leyton F (April 2021). "Vortioxetine for generalised anxiety disorder in adults". Medwave (in Spanish). 21 (3): e8172. doi:10.5867/medwave.2021.03.8171. PMID 34038400.
Kong W, Deng H, Wan J, Zhou Y, Zhou Y, Song B, Wang X (2020). "Comparative Remission Rates and Tolerability of Drugs for Generalised Anxiety Disorder: A Systematic Review and Network Meta-analysis of Double-Blind Randomized Controlled Trials". Front Pharmacol. 11: 580858. doi:10.3389/fphar.2020.580858. PMC 7741609. PMID 33343351.
Jacobsen PL, Mahableshwarkar AR, Serenko M, Chan S, Trivedi MH (May 2015). "A randomized, double-blind, placebo-controlled study of the efficacy and safety of vortioxetine 10 mg and 20 mg in adults with major depressive disorder". J Clin Psychiatry. 76 (5): 575–82. doi:10.4088/JCP.14m09335. PMID 26035185.
Mahableshwarkar AR, Jacobsen PL, Chen Y, Serenko M, Trivedi MH (June 2015). "A randomized, double-blind, duloxetine-referenced study comparing efficacy and tolerability of 2 fixed doses of vortioxetine in the acute treatment of adults with MDD". Psychopharmacology (Berl). 232 (12): 2061–70. doi:10.1007/s00213-014-3839-0. PMC 4432084. PMID 25575488.
Dubovsky SL (May 2014). "Pharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder". Expert Opinion on Drug Metabolism & Toxicology. 10 (5): 759–66. doi:10.1517/17425255.2014.904286. PMID 24684240. S2CID 9721842.
Chokka PR, Hankey JR (January 2018). "Assessment and management of sexual dysfunction in the context of depression". Ther Adv Psychopharmacol. 8 (1): 13–23. doi:10.1177/2045125317720642. PMC 5761906. PMID 29344340.
Fagiolini A, Florea I, Loft H, Christensen MC (March 2021). "Effectiveness of Vortioxetine on Emotional Blunting in Patients with Major Depressive Disorder with inadequate response to SSRI/SNRI treatment". Journal of Affective Disorders. 283: 472–479. doi:10.1016/j.jad.2020.11.106. hdl:11365/1137950. PMID 33516560.
Hughes S, Lacasse J, Fuller RR, Spaulding-Givens J (September 2017). "Adverse effects and treatment satisfaction among online users of four antidepressants". Psychiatry Research. 255: 78–86. doi:10.1016/j.psychres.2017.05.021. PMID 28531820. S2CID 4572360.
Moore N, Bang-Andersen B, Brennum L, Fredriksen K, Hogg S, Mork A, et al. (August 2008). "Lu AA21004: a novel potential treatment for mood disorders". European Neuropsychopharmacology. 18 (Supplement 4): S321. doi:10.1016/S0924-977X(08)70440-1. S2CID 54253895.
Bang-Andersen B, Ruhland T, Jørgensen M, Smith G, Frederiksen K, Jensen KG, et al. (May 2011). "Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder". Journal of Medicinal Chemistry. 54 (9): 3206–3221. doi:10.1021/jm101459g. PMID 21486038.
Sanchez C, Asin KE, Artigas F (January 2015). "Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data". Pharmacology & Therapeutics. 145: 43–57. doi:10.1016/j.pharmthera.2014.07.001. PMID 25016186.
Leiser SC, Iglesias-Bregna D, Westrich L, Pehrson AL, Sanchez C (October 2015). "Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism". Journal of Psychopharmacology. 29 (10): 1092–1105. doi:10.1177/0269881115592347. PMC 4579402. PMID 26174134.
Stenkrona P, Halldin C, Lundberg J (October 2013). "5-HTT and 5-HT(1A) receptor occupancy of the novel substance vortioxetine (Lu AA21004). A PET study in control subjects". European Neuropsychopharmacology. 23 (10): 1190–8. doi:10.1016/j.euroneuro.2013.01.002. PMID 23428337. S2CID 44631551.
Fu J, Chen Y (January 2015). "The efficacy and safety of 5 mg/d Vortioxetine compared to placebo for major depressive disorder: A meta-analysis". Psychopharmacology (Berl). 232 (1): 7–16. doi:10.1007/s00213-014-3633-z. PMID 24871704. S2CID 17263858.
Preskorn SH (January 2012). "The use of biomarkers in psychiatric research: how serotonin transporter occupancy explains the dose-response curves of SSRIs". Journal of Psychiatric Practice. 18 (1): 38–45. doi:10.1097/01.pra.0000410986.61593.46. PMID 22261982. S2CID 30529325.
Matsuno K, Nakamura K, Aritomi Y, Nishimura A (March 2018). "Pharmacokinetics, Safety, and Tolerability of Vortioxetine Following Single- and Multiple-Dose Administration in Healthy Japanese Adults". Clin Pharmacol Drug Dev. 7 (3): 319–331. doi:10.1002/cpdd.381. PMC 5900865. PMID 28941196.
Vieta E, Florea I, Schmidt SN, Areberg J, Ettrup A (July 2019). "Intravenous vortioxetine to accelerate onset of effect in major depressive disorder: a 2-week, randomized, double-blind, placebo-controlled study". Int Clin Psychopharmacol. 34 (4): 153–160. doi:10.1097/YIC.0000000000000271. PMC 6587371. PMID 31094901.
Orsolini L, Tomasetti C, Valchera A, Iasevoli F, Buonaguro EF, Vellante F, et al. (May 2016). "New advances in the treatment of generalized anxiety disorder: the multimodal antidepressant vortioxetine". Expert Review of Neurotherapeutics. 16 (5): 483–95. doi:10.1586/14737175.2016.1173545. PMID 27050932. S2CID 4768865.
Biederman J, Lindsten A, Sluth LB, Petersen ML, Ettrup A, Eriksen HF, Fava M (April 2019). "Vortioxetine for attention deficit hyperactivity disorder in adults: A randomized, double-blind, placebo-controlled, proof-of-concept study". Journal of Psychopharmacology. 33 (4): 511–521. doi:10.1177/0269881119832538. PMID 30843450. S2CID 73498106.
Liebowitz MR, Careri J, Blatt K, Draine A, Morita J, Moran M, Hanover R (December 2017). "Vortioxetine versus placebo in major depressive disorder comorbid with social anxiety disorder". Depression and Anxiety. 34 (12): 1164–1172. doi:10.1002/da.22702. PMID 29166552. S2CID 37489812.
Alcántara Montero A, Pacheco de Vasconcelos SR (July 2021). "Role of vortioxetine in the treatment of neuropathic pain". Revista Espanola de Anestesiologia y Reanimacion. doi:10.1016/j.redar.2021.04.001. PMID 34243960. S2CID 241004816.
Bennabi D, Haffen E, Van Waes V (2019). "Vortioxetine for Cognitive Enhancement in Major Depression: From Animal Models to Clinical Research". Frontiers in Psychiatry. 10: 771. doi:10.3389/fpsyt.2019.00771. PMC 6851880. PMID 31780961.

drugs.com

"Vortioxetine Hydrobromide Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 18 March 2019.

europa.eu

ema.europa.eu

"Brintellix EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 15 January 2021.
"Brintellix". European Medicines Agency. Archived from the original on 26 January 2016. Retrieved 19 January 2016.

fda.gov

"FDA approves new drug to treat major depressive disorder". U.S. Food and Drug Administration Press Announcement. Archived from the original on 3 October 2013.
"Safety Alerts for Human Medical Products - Brintellix (vortioxetine): Drug Safety Communication - Brand Name Change to Trintellix, to Avoid Confusion With Antiplatelet Drug Brilinta (ticagrelor". U.S. Food and Drug Administration (FDA). Archived from the original on 5 May 2016. Retrieved 2 May 2016.

nctr-crs.fda.gov

"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.

firstwordpharma.com

Beaulieu D (5 September 2007). "Lundbeck, Takeda enter strategic alliance for mood disorder, anxiety drugs". First Word Pharma. Archived from the original on 10 October 2016.

glgroup.com

"Lundbeck's "Serotonin Modulator and Stimulator" Lu AA21004: How Novel? How Good? - GLG News". Archived from the original on 24 July 2011.

handle.net

hdl.handle.net

Fagiolini A, Florea I, Loft H, Christensen MC (March 2021). "Effectiveness of Vortioxetine on Emotional Blunting in Patients with Major Depressive Disorder with inadequate response to SSRI/SNRI treatment". Journal of Affective Disorders. 283: 472–479. doi:10.1016/j.jad.2020.11.106. hdl:11365/1137950. PMID 33516560.

in.gov.br

Anvisa (31 March 2023). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.

medicines.org.uk

"Brintellix tablets 5, 10 and 20mg - Summary of Product Characteristics (SmPC)". (emc). 11 April 2022. Retrieved 19 December 2022.

nih.gov

pubmed.ncbi.nlm.nih.gov

Chen G, Højer AM, Areberg J, Nomikos G (June 2018). "Vortioxetine: Clinical Pharmacokinetics and Drug Interactions". Clinical Pharmacokinetics. 57 (6): 673–686. doi:10.1007/s40262-017-0612-7. PMC 5973995. PMID 29189941.
Keks NA, Hope J, Culhane C (June 2015). "Vortioxetine: A multimodal antidepressant or another selective serotonin reuptake inhibitor?". Australas Psychiatry. 23 (3): 210–3. doi:10.1177/1039856215581297. PMID 25907797. S2CID 21642202.
Zhang J, Mathis MV, Sellers JW, Kordzakhia G, Jackson AJ, Dow A, Yang P, Fossom L, Zhu H, Patel H, Unger EF, Temple RJ (January 2015). "The US Food and Drug Administration's perspective on the new antidepressant vortioxetine". J Clin Psychiatry. 76 (1): 8–14. doi:10.4088/JCP.14r09164. PMID 25562777.
Gibb A, Deeks ED (January 2014). "Vortioxetine: first global approval". Drugs. 74 (1): 135–145. doi:10.1007/s40265-013-0161-9. PMID 24311349. S2CID 5987668.
Long JD (September 2019). "Vortioxetine for Depression in Adults". Issues in Mental Health Nursing. 40 (9). Informa UK Limited: 819–820. doi:10.1080/01612840.2019.1604920. PMID 31225773. S2CID 195192772.
Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JP, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JP, Geddes JR (April 2018). "Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis". Lancet. 391 (10128): 1357–1366. doi:10.1016/S0140-6736(17)32802-7. PMC 5889788. PMID 29477251.
Sowa-Kućma M, Pańczyszyn-Trzewik P, Misztak P, Jaeschke RR, Sendek K, Styczeń K, Datka W, Koperny M (August 2017). "Vortioxetine: A review of the pharmacology and clinical profile of the novel antidepressant". Pharmacol Rep. 69 (4): 595–601. doi:10.1016/j.pharep.2017.01.030. PMID 28499187. S2CID 43104089.
Connolly KR, Thase ME (2016). "Vortioxetine: a New Treatment for Major Depressive Disorder". Expert Opinion on Pharmacotherapy. 17 (3): 421–31. doi:10.1517/14656566.2016.1133588. PMID 26679430. S2CID 40432194. The authors suggest that vortioxetine is currently a good second-line antidepressant option and shows promise, pending additional long-term data, to become a first-line antidepressant option.
Köhler S, Cierpinsky K, Kronenberg G, Adli M (January 2016). "The serotonergic system in the neurobiology of depression: Relevance for novel antidepressants". Journal of Psychopharmacology. 30 (1): 13–22. doi:10.1177/0269881115609072. PMID 26464458. S2CID 21501578.
Kelliny M, Croarkin PE, Moore KM, Bobo WV (2015). "Profile of vortioxetine in the treatment of major depressive disorder: an overview of the primary and secondary literature". Therapeutics and Clinical Risk Management. 11: 1193–212. doi:10.2147/TCRM.S55313. PMC 4542474. PMID 26316764.
Koesters M, Ostuzzi G, Guaiana G, Breilmann J, Barbui C (July 2017). "Vortioxetine for depression in adults". The Cochrane Database of Systematic Reviews. 2017 (7): CD011520. doi:10.1002/14651858.CD011520.pub2. PMC 6483322. PMID 28677828.
Mattingly GW, Ren H, Christensen MC, Katzman MA, Polosan M, Simonsen K, Hammer-Helmich L (2022). "Effectiveness of Vortioxetine in Patients With Major Depressive Disorder in Real-World Clinical Practice: Results of the RELIEVE Study". Frontiers in Psychiatry. 13: 824831. doi:10.3389/fpsyt.2022.824831. PMC 8959350. PMID 35356713.
Pae CU, Wang SM, Han C, Lee SJ, Patkar AA, Masand PS, Serretti A (May 2015). "Vortioxetine, a multimodal antidepressant for generalized anxiety disorder: a systematic review and meta-analysis". Journal of Psychiatric Research. 64: 88–98. doi:10.1016/j.jpsychires.2015.02.017. PMID 25851751.
Fu J, Peng L, Li X (19 April 2016). "The efficacy and safety of multiple doses of vortioxetine for generalized anxiety disorder: a meta-analysis". Neuropsychiatric Disease and Treatment. 12: 951–9. doi:10.2147/NDT.S104050. PMC 4844447. PMID 27143896.
Qin B, Huang G, Yang Q, Zhao M, Chen H, Gao W, Yang M (November 2019). "Vortioxetine treatment for generalised anxiety disorder: a meta-analysis of anxiety, quality of life and safety outcomes". BMJ Open. 9 (11): e033161. doi:10.1136/bmjopen-2019-033161. PMC 6924794. PMID 31784448.
Yee A, Ng CG, Seng LH (2018). "Vortioxetine Treatment for Anxiety Disorder: A Meta-Analysis Study". Current Drug Targets. 19 (12): 1412–1423. doi:10.2174/1389450118666171117131151. PMID 29149828. S2CID 11855728.
Meza N, Leyton F (April 2021). "Vortioxetine for generalised anxiety disorder in adults". Medwave (in Spanish). 21 (3): e8172. doi:10.5867/medwave.2021.03.8171. PMID 34038400.
Kong W, Deng H, Wan J, Zhou Y, Zhou Y, Song B, Wang X (2020). "Comparative Remission Rates and Tolerability of Drugs for Generalised Anxiety Disorder: A Systematic Review and Network Meta-analysis of Double-Blind Randomized Controlled Trials". Front Pharmacol. 11: 580858. doi:10.3389/fphar.2020.580858. PMC 7741609. PMID 33343351.
Jacobsen PL, Mahableshwarkar AR, Serenko M, Chan S, Trivedi MH (May 2015). "A randomized, double-blind, placebo-controlled study of the efficacy and safety of vortioxetine 10 mg and 20 mg in adults with major depressive disorder". J Clin Psychiatry. 76 (5): 575–82. doi:10.4088/JCP.14m09335. PMID 26035185.
Mahableshwarkar AR, Jacobsen PL, Chen Y, Serenko M, Trivedi MH (June 2015). "A randomized, double-blind, duloxetine-referenced study comparing efficacy and tolerability of 2 fixed doses of vortioxetine in the acute treatment of adults with MDD". Psychopharmacology (Berl). 232 (12): 2061–70. doi:10.1007/s00213-014-3839-0. PMC 4432084. PMID 25575488.
Dubovsky SL (May 2014). "Pharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder". Expert Opinion on Drug Metabolism & Toxicology. 10 (5): 759–66. doi:10.1517/17425255.2014.904286. PMID 24684240. S2CID 9721842.
Chokka PR, Hankey JR (January 2018). "Assessment and management of sexual dysfunction in the context of depression". Ther Adv Psychopharmacol. 8 (1): 13–23. doi:10.1177/2045125317720642. PMC 5761906. PMID 29344340.
Fagiolini A, Florea I, Loft H, Christensen MC (March 2021). "Effectiveness of Vortioxetine on Emotional Blunting in Patients with Major Depressive Disorder with inadequate response to SSRI/SNRI treatment". Journal of Affective Disorders. 283: 472–479. doi:10.1016/j.jad.2020.11.106. hdl:11365/1137950. PMID 33516560.
Hughes S, Lacasse J, Fuller RR, Spaulding-Givens J (September 2017). "Adverse effects and treatment satisfaction among online users of four antidepressants". Psychiatry Research. 255: 78–86. doi:10.1016/j.psychres.2017.05.021. PMID 28531820. S2CID 4572360.
Bang-Andersen B, Ruhland T, Jørgensen M, Smith G, Frederiksen K, Jensen KG, et al. (May 2011). "Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder". Journal of Medicinal Chemistry. 54 (9): 3206–3221. doi:10.1021/jm101459g. PMID 21486038.
Sanchez C, Asin KE, Artigas F (January 2015). "Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data". Pharmacology & Therapeutics. 145: 43–57. doi:10.1016/j.pharmthera.2014.07.001. PMID 25016186.
Leiser SC, Iglesias-Bregna D, Westrich L, Pehrson AL, Sanchez C (October 2015). "Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism". Journal of Psychopharmacology. 29 (10): 1092–1105. doi:10.1177/0269881115592347. PMC 4579402. PMID 26174134.
Stenkrona P, Halldin C, Lundberg J (October 2013). "5-HTT and 5-HT(1A) receptor occupancy of the novel substance vortioxetine (Lu AA21004). A PET study in control subjects". European Neuropsychopharmacology. 23 (10): 1190–8. doi:10.1016/j.euroneuro.2013.01.002. PMID 23428337. S2CID 44631551.
Fu J, Chen Y (January 2015). "The efficacy and safety of 5 mg/d Vortioxetine compared to placebo for major depressive disorder: A meta-analysis". Psychopharmacology (Berl). 232 (1): 7–16. doi:10.1007/s00213-014-3633-z. PMID 24871704. S2CID 17263858.
Preskorn SH (January 2012). "The use of biomarkers in psychiatric research: how serotonin transporter occupancy explains the dose-response curves of SSRIs". Journal of Psychiatric Practice. 18 (1): 38–45. doi:10.1097/01.pra.0000410986.61593.46. PMID 22261982. S2CID 30529325.
Matsuno K, Nakamura K, Aritomi Y, Nishimura A (March 2018). "Pharmacokinetics, Safety, and Tolerability of Vortioxetine Following Single- and Multiple-Dose Administration in Healthy Japanese Adults". Clin Pharmacol Drug Dev. 7 (3): 319–331. doi:10.1002/cpdd.381. PMC 5900865. PMID 28941196.
Vieta E, Florea I, Schmidt SN, Areberg J, Ettrup A (July 2019). "Intravenous vortioxetine to accelerate onset of effect in major depressive disorder: a 2-week, randomized, double-blind, placebo-controlled study". Int Clin Psychopharmacol. 34 (4): 153–160. doi:10.1097/YIC.0000000000000271. PMC 6587371. PMID 31094901.
Orsolini L, Tomasetti C, Valchera A, Iasevoli F, Buonaguro EF, Vellante F, et al. (May 2016). "New advances in the treatment of generalized anxiety disorder: the multimodal antidepressant vortioxetine". Expert Review of Neurotherapeutics. 16 (5): 483–95. doi:10.1586/14737175.2016.1173545. PMID 27050932. S2CID 4768865.
Biederman J, Lindsten A, Sluth LB, Petersen ML, Ettrup A, Eriksen HF, Fava M (April 2019). "Vortioxetine for attention deficit hyperactivity disorder in adults: A randomized, double-blind, placebo-controlled, proof-of-concept study". Journal of Psychopharmacology. 33 (4): 511–521. doi:10.1177/0269881119832538. PMID 30843450. S2CID 73498106.
Liebowitz MR, Careri J, Blatt K, Draine A, Morita J, Moran M, Hanover R (December 2017). "Vortioxetine versus placebo in major depressive disorder comorbid with social anxiety disorder". Depression and Anxiety. 34 (12): 1164–1172. doi:10.1002/da.22702. PMID 29166552. S2CID 37489812.
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