Rogers, AR; Bohlender, RJ; Huff, CD (2017). «Early history of Neanderthals and Denisovans». Proc Natl Acad Sci U S A114 (37): 9859-9863. PMC5604018. PMID28784789. doi:10.1073/PNAS.1706426114.;
see also:
Jordana Cepelewicz, Genetics Spills Secrets From Neanderthals' Lost History, Quanta Magazine, 18 September 2017.
"The dating of that schism between the Neanderthals and the Denisovans is surprising because previous research had pegged it as much more recent: a 2016 study, for instance, set it at only 450,000 years ago. An earlier separation means we should expect to find many more fossils of both eventually. It also changes the interpretation of some fossils that have been found. Take the large-brained hominid bones belonging to a species called Homo heidelbergensis, which lived in Europe and Asia around 600,000 years ago. Paleoanthropologists have disagreed about how they relate to other human groups, some positing they were ancestors of both modern humans and Neanderthals, others that they were a nonancestral species replaced by the Neanderthals, who spread across Europe."
Zeberg, Hugo; Pääbo, Svante (30 de septiembre de 2020). «The major genetic risk factor for severe COVID-19 is inherited from Neandertals». Nature587 (7835): 610-612. PMID32998156. doi:10.1038/s41586-020-2818-3. «[...] the risk is conferred by a genomic segment of around 50 kilobases in size that is inherited from Neanderthals and is carried by around 50% of people in south Asia and around 16% of people in Europe.»
Pratas, D; Hosseini, M; Silva, R; Pinho, A; Ferreira, P (June 20–23, 2017). Visualization of Distinct DNA Regions of the Modern Human Relatively to a Neanderthal Genome. Lecture Notes in Computer Science 10255. pp. 235-42. ISBN978-3-319-58837-7. doi:10.1007/978-3-319-58838-4_26.
Ding, Q (31 de agosto de 2014). «Neanderthal origin of the haplotypes carrying the functional variant Val92Met in the MC1R in modern humans.». Molecular Biology and Evolution31 (8): 1994-2003. PMID24916031. doi:10.1093/molbev/msu180.
Lowery, Robert K.; Uribe, Gabriel; Jimenez, Eric B.; Weiss, Mark A.; Herrera, Kristian J.; Regueiro, Maria; Herrera, Rene J. (2013). «Neanderthal and Denisova genetic affinities with contemporary humans: Introgression versus common ancestral polymorphisms». Gene530 (1): 83-94. ISSN0378-1119. PMID23872234. doi:10.1016/j.gene.2013.06.005.
"Specifically, genes in the LCP [lipid catabolic process] term had the greatest excess of NLS in populations of European descent, with an average NLS frequency of 20.8±2.6% versus 5.9±0.08% genome wide (two-sided t-test, P<0.0001, n=379 Europeans and n=246 Africans). Further, among examined out-of-Africa human populations, the excess of NLS [Neanderthal-like genomic sites] in LCP genes was only observed in individuals of European descent: the average NLS frequency in Asians is 6.7±0.7% in LCP genes versus 6.2±0.06% genome wide."
Khrameeva, Ekaterina E.; Bozek, Katarzyna; He, Liu; Yan, Zheng; Jiang, Xi; Wei, Yuning; Tang, Kun; Gelfand, Mikhail S. et al. (2014). «Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans». Nature Communications5: 3584. Bibcode:2014NatCo...5.3584K. PMC3988804. PMID24690587. doi:10.1038/ncomms4584.Se sugiere usar |número-autores= (ayuda).
"Specifically, genes in the LCP [lipid catabolic process] term had the greatest excess of NLS in populations of European descent, with an average NLS frequency of 20.8±2.6% versus 5.9±0.08% genome wide (two-sided t-test, P<0.0001, n=379 Europeans and n=246 Africans). Further, among examined out-of-Africa human populations, the excess of NLS [Neanderthal-like genomic sites] in LCP genes was only observed in individuals of European descent: the average NLS frequency in Asians is 6.7±0.7% in LCP genes versus 6.2±0.06% genome wide."
Khrameeva, Ekaterina E.; Bozek, Katarzyna; He, Liu; Yan, Zheng; Jiang, Xi; Wei, Yuning; Tang, Kun; Gelfand, Mikhail S. et al. (2014). «Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans». Nature Communications5: 3584. Bibcode:2014NatCo...5.3584K. PMC3988804. PMID24690587. doi:10.1038/ncomms4584.Se sugiere usar |número-autores= (ayuda).
Lowery, Robert K.; Uribe, Gabriel; Jimenez, Eric B.; Weiss, Mark A.; Herrera, Kristian J.; Regueiro, Maria; Herrera, Rene J. (2013). «Neanderthal and Denisova genetic affinities with contemporary humans: Introgression versus common ancestral polymorphisms». Gene530 (1): 83-94. ISSN0378-1119. PMID23872234. doi:10.1016/j.gene.2013.06.005.
Rogers, AR; Bohlender, RJ; Huff, CD (2017). «Early history of Neanderthals and Denisovans». Proc Natl Acad Sci U S A114 (37): 9859-9863. PMC5604018. PMID28784789. doi:10.1073/PNAS.1706426114.;
see also:
Jordana Cepelewicz, Genetics Spills Secrets From Neanderthals' Lost History, Quanta Magazine, 18 September 2017.
"The dating of that schism between the Neanderthals and the Denisovans is surprising because previous research had pegged it as much more recent: a 2016 study, for instance, set it at only 450,000 years ago. An earlier separation means we should expect to find many more fossils of both eventually. It also changes the interpretation of some fossils that have been found. Take the large-brained hominid bones belonging to a species called Homo heidelbergensis, which lived in Europe and Asia around 600,000 years ago. Paleoanthropologists have disagreed about how they relate to other human groups, some positing they were ancestors of both modern humans and Neanderthals, others that they were a nonancestral species replaced by the Neanderthals, who spread across Europe."
Zeberg, Hugo; Pääbo, Svante (30 de septiembre de 2020). «The major genetic risk factor for severe COVID-19 is inherited from Neandertals». Nature587 (7835): 610-612. PMID32998156. doi:10.1038/s41586-020-2818-3. «[...] the risk is conferred by a genomic segment of around 50 kilobases in size that is inherited from Neanderthals and is carried by around 50% of people in south Asia and around 16% of people in Europe.»
Ding, Q (31 de agosto de 2014). «Neanderthal origin of the haplotypes carrying the functional variant Val92Met in the MC1R in modern humans.». Molecular Biology and Evolution31 (8): 1994-2003. PMID24916031. doi:10.1093/molbev/msu180.
Lowery, Robert K.; Uribe, Gabriel; Jimenez, Eric B.; Weiss, Mark A.; Herrera, Kristian J.; Regueiro, Maria; Herrera, Rene J. (2013). «Neanderthal and Denisova genetic affinities with contemporary humans: Introgression versus common ancestral polymorphisms». Gene530 (1): 83-94. ISSN0378-1119. PMID23872234. doi:10.1016/j.gene.2013.06.005.
"Specifically, genes in the LCP [lipid catabolic process] term had the greatest excess of NLS in populations of European descent, with an average NLS frequency of 20.8±2.6% versus 5.9±0.08% genome wide (two-sided t-test, P<0.0001, n=379 Europeans and n=246 Africans). Further, among examined out-of-Africa human populations, the excess of NLS [Neanderthal-like genomic sites] in LCP genes was only observed in individuals of European descent: the average NLS frequency in Asians is 6.7±0.7% in LCP genes versus 6.2±0.06% genome wide."
Khrameeva, Ekaterina E.; Bozek, Katarzyna; He, Liu; Yan, Zheng; Jiang, Xi; Wei, Yuning; Tang, Kun; Gelfand, Mikhail S. et al. (2014). «Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans». Nature Communications5: 3584. Bibcode:2014NatCo...5.3584K. PMC3988804. PMID24690587. doi:10.1038/ncomms4584.Se sugiere usar |número-autores= (ayuda).
Rogers, AR; Bohlender, RJ; Huff, CD (2017). «Early history of Neanderthals and Denisovans». Proc Natl Acad Sci U S A114 (37): 9859-9863. PMC5604018. PMID28784789. doi:10.1073/PNAS.1706426114.;
see also:
Jordana Cepelewicz, Genetics Spills Secrets From Neanderthals' Lost History, Quanta Magazine, 18 September 2017.
"The dating of that schism between the Neanderthals and the Denisovans is surprising because previous research had pegged it as much more recent: a 2016 study, for instance, set it at only 450,000 years ago. An earlier separation means we should expect to find many more fossils of both eventually. It also changes the interpretation of some fossils that have been found. Take the large-brained hominid bones belonging to a species called Homo heidelbergensis, which lived in Europe and Asia around 600,000 years ago. Paleoanthropologists have disagreed about how they relate to other human groups, some positing they were ancestors of both modern humans and Neanderthals, others that they were a nonancestral species replaced by the Neanderthals, who spread across Europe."
