Sign In

Login

Password

Forgot Password ? Sign Up

Mdm2 (Spanish Wikipedia)

Analysis of information sources in references of the Wikipedia article "Mdm2" in Spanish language version.

refsWebsite
Global rank Spanish rank
48nih.gov
4th place
4th place
32doi.org
2nd place
2nd place
28issn.org
57th place
3rd place
1archive.org
6th place
5th place

archive.org (Global: 6th place; Spanish: 5th place)

doi.org (Global: 2nd place; Spanish: 2nd place)

dx.doi.org

  • Chène, Patrick (2003-02). «Inhibiting the p53–MDM2 interaction: an important target for cancer therapy». Nature Reviews Cancer 3 (2): 102-109. ISSN 1474-175X. doi:10.1038/nrc991. Consultado el 7 de diciembre de 2025. 
  • Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA (2004). «In vivo activation of the p53 pathway by small-molecule antagonists of MDM2». Science 6: 844-848. PMID 14704432. doi:10.1126/science.1092472. 
  • Ofir-Rosenfeld, Yaara; Boggs Kristy, Michael Dan, Kastan Michael B, Oren Moshe (Oct. de 2008). «Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26». Mol. Cell (United States) 32 (2): 180-9. PMID 18951086. doi:10.1016/j.molcel.2008.08.031. 
  • Ochocka, Anna Maria; Kampanis Petros, Nicol Samantha, Allende-Vega Nerea, Cox Miranda, Marcar Lynnette, Milne Diane, Fuller-Pace Frances, Meek David (Feb. de 2009). «FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53». FEBS Lett. (Netherlands) 583 (4): 621-6. PMID 19166840. doi:10.1016/j.febslet.2009.01.009. 
  • Legube, Gaëlle; Linares Laetitia K, Lemercier Claudie, Scheffner Martin, Khochbin Saadi, Trouche Didier (Apr. de 2002). «Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation». EMBO J. (England) 21 (7): 1704-12. ISSN 0261-4189. PMID 11927554. doi:10.1093/emboj/21.7.1704. 
  • Dai, Mu-Shui; Sun Xiao-Xin, Lu Hua (Jul. de 2008). «Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2». Mol. Cell. Biol. (United States) 28 (13): 4365-76. PMID 18426907. doi:10.1128/MCB.01662-07. 
  • Zhang, Zhuo; Zhang Ruiwen (Mar. de 2008). «Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation». EMBO J. (England) 27 (6): 852-64. PMID 18309296. doi:10.1038/emboj.2008.25. 
  • Sehat, Bita; Andersson Sandra, Girnita Leonard, Larsson Olle (Jul. de 2008). «Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis». Cancer Res. (United States) 68 (14): 5669-77. PMID 18632619. doi:10.1158/0008-5472.CAN-07-6364. 
  • Chang, Lufen; Zhou Bingsen, Hu Shuya, Guo Robin, Liu Xiyong, Jones Stephen N, Yen Yun (Nov. de 2008). «ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage». Proc. Natl. Acad. Sci. U.S.A. (United States) 105 (47): 18519-24. PMID 19015526. doi:10.1073/pnas.0803313105. 
  • Brenkman, Arjan B; de Keizer Peter L J, van den Broek Niels J F, Jochemsen A G, Burgering Boudewijn M Th (2008). «Mdm2 induces mono-ubiquitination of FOXO4». PLoS ONE (United States) 3 (7): e2819. PMID 18665269. doi:10.1371/journal.pone.0002819. 
  • Goldberg, Zehavit; Vogt Sionov Ronit, Berger Michael, Zwang Yaara, Perets Ruth, Van Etten Richard A, Oren Moshe, Taya Yoichi, Haupt Ygal (Jul. de 2002). «Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation». EMBO J. (England) 21 (14): 3715-27. ISSN 0261-4189. PMID 12110584. doi:10.1093/emboj/cdf384. 
  • Chen, Deng; Zhang Jianbing, Li Mao, Rayburn Elizabeth R, Wang Hui, Zhang Ruiwen (Feb. de 2009). «RYBP stabilizes p53 by modulating MDM2». EMBO Rep. (England) 10 (2): 166-72. PMID 19098711. doi:10.1038/embor.2008.231. 
  • Chen, Delin; Li Muyang, Luo Jianyuan, Gu Wei (Apr. de 2003). «Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function». J. Biol. Chem. (United States) 278 (16): 13595-8. ISSN 0021-9258. PMID 12606552. doi:10.1074/jbc.C200694200. 
  • Jin, Yetao; Zeng Shelya X, Dai Mu-Shui, Yang Xiang-Jiao, Lu Hua (Aug. de 2002). «MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation». J. Biol. Chem. (United States) 277 (34): 30838-43. ISSN 0021-9258. PMID 12068014. doi:10.1074/jbc.M204078200. 
  • Bálint, E; Bates S, Vousden K H (Jul. de 1999). «Mdm2 binds p73 alpha without targeting degradation». Oncogene (ENGLAND) 18 (27): 3923-9. ISSN 0950-9232. PMID 10435614. doi:10.1038/sj.onc.1202781. 
  • Colaluca, Ivan N; Tosoni Daniela, Nuciforo Paolo, Senic-Matuglia Francesca, Galimberti Viviana, Viale Giuseppe, Pece Salvatore, Di Fiore Pier Paolo (Jan. de 2008). «NUMB controls p53 tumour suppressor activity». Nature (England) 451 (7174): 76-80. PMID 18172499. doi:10.1038/nature06412. 
  • Haupt Y, Maya R, Kazaz A, Oren M (mayo de 1997). «Mdm2 promotes the rapid degradation of p53». Nature 387 (6630): 296-9. PMID 9153395. doi:10.1038/387296a0. 
  • Clark, Paula A; Llanos Susana, Peters Gordon (Jul. de 2002). «Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2». Oncogene (England) 21 (29): 4498-507. ISSN 0950-9232. PMID 12085228. doi:10.1038/sj.onc.1205558. 
  • Qiu W, Wu J, Walsh EM, et al. (julio de 2008). «Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells». Oncogene 27 (29): 4034-43. PMID 18332869. doi:10.1038/onc.2008.43. 
  • Kadakia, Madhavi; Brown Thomas L, McGorry Molly M, Berberich Steven J (Dec. de 2002). «MdmX inhibits Smad transactivation». Oncogene (England) 21 (57): 8776-85. ISSN 0950-9232. PMID 12483531. doi:10.1038/sj.onc.1205993. 
  • Badciong, James C; Haas Arthur L (Dec. de 2002). «MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination». J. Biol. Chem. (United States) 277 (51): 49668-75. ISSN 0021-9258. PMID 12393902. doi:10.1074/jbc.M208593200. 
  • Linke, K; Mace P D, Smith C A, Vaux D L, Silke J, Day C L (mayo. de 2008). «Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans». Cell Death Differ. (England) 15 (5): 841-8. ISSN 1350-9047. PMID 18219319. doi:10.1038/sj.cdd.4402309. 
  • Bernardi, Rosa; Scaglioni Pier Paolo, Bergmann Stephan, Horn Henning F, Vousden Karen H, Pandolfi Pier Paolo (Jul. de 2004). «PML regulates p53 stability by sequestering Mdm2 to the nucleolus». Nat. Cell Biol. (England) 6 (7): 665-72. ISSN 1465-7392. PMID 15195100. doi:10.1038/ncb1147. 
  • Zhu, Hongyan; Wu Liqing, Maki Carl G (Dec. de 2003). «MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53». J. Biol. Chem. (United States) 278 (49): 49286-92. ISSN 0021-9258. PMID 14507915. doi:10.1074/jbc.M308302200. 
  • Kurki S, Latonen L, Laiho M (octubre de 2003). «Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization». J. Cell. Sci. 116 (Pt 19): 3917-25. PMID 12915590. doi:10.1242/jcs.00714. 
  • Wei, Xiaolong; Yu Zhong Kang, Ramalingam Arivudainambi, Grossman Steven R, Yu Jiang H, Bloch Donald B, Maki Carl G (Aug. de 2003). «Physical and functional interactions between PML and MDM2». J. Biol. Chem. (United States) 278 (31): 29288-97. ISSN 0021-9258. PMID 12759344. doi:10.1074/jbc.M212215200. 
  • Maguire, Maria; Nield Paul C, Devling Timothy, Jenkins Rosalind E, Park B Kevin, Polański Radoslaw, Vlatković Nikolina, Boyd Mark T (mayo. de 2008). «MDM2 regulates dihydrofolate reductase activity through monoubiquitination». Cancer Res. (United States) 68 (9): 3232-42. PMID 18451149. doi:10.1158/0008-5472.CAN-07-5271. 
  • Wang, Ping; Gao Hua, Ni Yanxiang, Wang Beibei, Wu Yalan, Ji Lili, Qin Linhua, Ma Lan, Pei Gang (Feb. de 2003). «Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2». J. Biol. Chem. (United States) 278 (8): 6363-70. ISSN 0021-9258. PMID 12488444. doi:10.1074/jbc.M210350200. 
  • Wang, Ping; Wu Yalan, Ge Xin, Ma Lan, Pei Gang (Mar. de 2003). «Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus». J. Biol. Chem. (United States) 278 (13): 11648-53. ISSN 0021-9258. PMID 12538596. doi:10.1074/jbc.M208109200. 
  • Shenoy, Sudha K; Xiao Kunhong, Venkataramanan Vidya, Snyder Peter M, Freedman Neil J, Weissman Allan M (Aug. de 2008). «Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor». J. Biol. Chem. (United States) 283 (32): 22166-76. ISSN 0021-9258. PMID 18544533. doi:10.1074/jbc.M709668200. 
  • Song, Min Sup; Song Su Jung, Kim So Yeon, Oh Hyun Jung, Lim Dae-Sik (Jul. de 2008). «The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex». EMBO J. (England) 27 (13): 1863-74. PMID 18566590. doi:10.1038/emboj.2008.115. 

doi.org

issn.org (Global: 57th place; Spanish: 3rd place)

portal.issn.org

  • Chène, Patrick (2003-02). «Inhibiting the p53–MDM2 interaction: an important target for cancer therapy». Nature Reviews Cancer 3 (2): 102-109. ISSN 1474-175X. doi:10.1038/nrc991. Consultado el 7 de diciembre de 2025. 
  • Ito, Akihiro; Kawaguchi Yoshiharu, Lai Chun-Hsiang, Kovacs Jeffrey J, Higashimoto Yuichiro, Appella Ettore, Yao Tso-Pang (Nov. de 2002). «MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation». EMBO J. (England) 21 (22): 6236-45. ISSN 0261-4189. PMID 12426395. 
  • Zhao, Lili; Samuels Tina, Winckler Sarah, Korgaonkar Chandrashekhar, Tompkins Van, Horne Mary C, Quelle Dawn E (Jan. de 2003). «Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways». Mol. Cancer Res. (United States) 1 (3): 195-206. ISSN 1541-7786. PMID 12556559. 
  • Legube, Gaëlle; Linares Laetitia K, Lemercier Claudie, Scheffner Martin, Khochbin Saadi, Trouche Didier (Apr. de 2002). «Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation». EMBO J. (England) 21 (7): 1704-12. ISSN 0261-4189. PMID 11927554. doi:10.1093/emboj/21.7.1704. 
  • Zhang, Yanping; Wolf Gabrielle White, Bhat Krishna, Jin Aiwen, Allio Theresa, Burkhart William A, Xiong Yue (Dec. de 2003). «Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway». Mol. Cell. Biol. (United States) 23 (23): 8902-12. ISSN 0270-7306. PMID 14612427. 
  • Marechal, V; Elenbaas B, Piette J, Nicolas J C, Levine A J (Nov. de 1994). «The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes». Mol. Cell. Biol. (UNITED STATES) 14 (11): 7414-20. ISSN 0270-7306. PMID 7935455. 
  • Goldberg, Zehavit; Vogt Sionov Ronit, Berger Michael, Zwang Yaara, Perets Ruth, Van Etten Richard A, Oren Moshe, Taya Yoichi, Haupt Ygal (Jul. de 2002). «Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation». EMBO J. (England) 21 (14): 3715-27. ISSN 0261-4189. PMID 12110584. doi:10.1093/emboj/cdf384. 
  • Chen, Delin; Li Muyang, Luo Jianyuan, Gu Wei (Apr. de 2003). «Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function». J. Biol. Chem. (United States) 278 (16): 13595-8. ISSN 0021-9258. PMID 12606552. doi:10.1074/jbc.C200694200. 
  • Ravi, R; Mookerjee B, Bhujwalla Z M, Sutter C H, Artemov D, Zeng Q, Dillehay L E, Madan A, Semenza G L, Bedi A (Jan. de 2000). «Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha». Genes Dev. (UNITED STATES) 14 (1): 34-44. ISSN 0890-9369. PMID 10640274. 
  • Jin, Yetao; Zeng Shelya X, Dai Mu-Shui, Yang Xiang-Jiao, Lu Hua (Aug. de 2002). «MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation». J. Biol. Chem. (United States) 277 (34): 30838-43. ISSN 0021-9258. PMID 12068014. doi:10.1074/jbc.M204078200. 
  • Léveillard, T; Wasylyk B (Dec. de 1997). «The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter». J. Biol. Chem. (UNITED STATES) 272 (49): 30651-61. ISSN 0021-9258. PMID 9388200. 
  • Thut, C J; Goodrich J A, Tjian R (Aug. de 1997). «Repression of p53-mediated transcription by MDM2: a dual mechanism». Genes Dev. (UNITED STATES) 11 (15): 1974-86. ISSN 0890-9369. PMID 9271120. 
  • Bálint, E; Bates S, Vousden K H (Jul. de 1999). «Mdm2 binds p73 alpha without targeting degradation». Oncogene (ENGLAND) 18 (27): 3923-9. ISSN 0950-9232. PMID 10435614. doi:10.1038/sj.onc.1202781. 
  • Zeng, X; Chen L, Jost C A, Maya R, Keller D, Wang X, Kaelin W G, Oren M, Chen J, Lu H (mayo. de 1999). «MDM2 suppresses p73 function without promoting p73 degradation». Mol. Cell. Biol. (UNITED STATES) 19 (5): 3257-66. ISSN 0270-7306. PMID 10207051. 
  • Mirnezami, Alexander H; Campbell Sandra J, Darley Matthew, Primrose John N, Johnson Peter W M, Blaydes Jeremy P (Jul. de 2003). «Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription». Curr. Biol. (England) 13 (14): 1234-9. ISSN 0960-9822. PMID 12867035. 
  • Yogosawa, Satomi; Miyauchi Yasuhiro, Honda Reiko, Tanaka Hirofumi, Yasuda Hideyo (Mar. de 2003). «Mammalian Numb is a target protein of Mdm2, ubiquitin ligase». Biochem. Biophys. Res. Commun. (United States) 302 (4): 869-72. ISSN 0006-291X. PMID 12646252. 
  • Clark, Paula A; Llanos Susana, Peters Gordon (Jul. de 2002). «Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2». Oncogene (England) 21 (29): 4498-507. ISSN 0950-9232. PMID 12085228. doi:10.1038/sj.onc.1205558. 
  • Pomerantz, J; Schreiber-Agus N, Liégeois N J, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee H W, Cordon-Cardo C, DePinho R A (Mar. de 1998). «The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53». Cell (UNITED STATES) 92 (6): 713-23. ISSN 0092-8674. PMID 9529248. 
  • Kadakia, Madhavi; Brown Thomas L, McGorry Molly M, Berberich Steven J (Dec. de 2002). «MdmX inhibits Smad transactivation». Oncogene (England) 21 (57): 8776-85. ISSN 0950-9232. PMID 12483531. doi:10.1038/sj.onc.1205993. 
  • Tanimura, S; Ohtsuka S; Mitsui K; Shirouzu K; Yoshimura A; Ohtsubo M (Mar. de 1999). «MDM2 interacts with MDMX through their RING finger domains». FEBS Lett. (NETHERLANDS) 447 (1): 5-9. ISSN 0014-5793. PMID 10218570. 
  • Badciong, James C; Haas Arthur L (Dec. de 2002). «MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination». J. Biol. Chem. (United States) 277 (51): 49668-75. ISSN 0021-9258. PMID 12393902. doi:10.1074/jbc.M208593200. 
  • Linke, K; Mace P D, Smith C A, Vaux D L, Silke J, Day C L (mayo. de 2008). «Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans». Cell Death Differ. (England) 15 (5): 841-8. ISSN 1350-9047. PMID 18219319. doi:10.1038/sj.cdd.4402309. 
  • Bernardi, Rosa; Scaglioni Pier Paolo, Bergmann Stephan, Horn Henning F, Vousden Karen H, Pandolfi Pier Paolo (Jul. de 2004). «PML regulates p53 stability by sequestering Mdm2 to the nucleolus». Nat. Cell Biol. (England) 6 (7): 665-72. ISSN 1465-7392. PMID 15195100. doi:10.1038/ncb1147. 
  • Zhu, Hongyan; Wu Liqing, Maki Carl G (Dec. de 2003). «MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53». J. Biol. Chem. (United States) 278 (49): 49286-92. ISSN 0021-9258. PMID 14507915. doi:10.1074/jbc.M308302200. 
  • Wei, Xiaolong; Yu Zhong Kang, Ramalingam Arivudainambi, Grossman Steven R, Yu Jiang H, Bloch Donald B, Maki Carl G (Aug. de 2003). «Physical and functional interactions between PML and MDM2». J. Biol. Chem. (United States) 278 (31): 29288-97. ISSN 0021-9258. PMID 12759344. doi:10.1074/jbc.M212215200. 
  • Wang, Ping; Gao Hua, Ni Yanxiang, Wang Beibei, Wu Yalan, Ji Lili, Qin Linhua, Ma Lan, Pei Gang (Feb. de 2003). «Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2». J. Biol. Chem. (United States) 278 (8): 6363-70. ISSN 0021-9258. PMID 12488444. doi:10.1074/jbc.M210350200. 
  • Wang, Ping; Wu Yalan, Ge Xin, Ma Lan, Pei Gang (Mar. de 2003). «Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus». J. Biol. Chem. (United States) 278 (13): 11648-53. ISSN 0021-9258. PMID 12538596. doi:10.1074/jbc.M208109200. 
  • Shenoy, Sudha K; Xiao Kunhong, Venkataramanan Vidya, Snyder Peter M, Freedman Neil J, Weissman Allan M (Aug. de 2008). «Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor». J. Biol. Chem. (United States) 283 (32): 22166-76. ISSN 0021-9258. PMID 18544533. doi:10.1074/jbc.M709668200. 

nih.gov (Global: 4th place; Spanish: 4th place)

ncbi.nlm.nih.gov

  • Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA (2004). «In vivo activation of the p53 pathway by small-molecule antagonists of MDM2». Science 6: 844-848. PMID 14704432. doi:10.1126/science.1092472. 
  • Ito, Akihiro; Kawaguchi Yoshiharu, Lai Chun-Hsiang, Kovacs Jeffrey J, Higashimoto Yuichiro, Appella Ettore, Yao Tso-Pang (Nov. de 2002). «MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation». EMBO J. (England) 21 (22): 6236-45. ISSN 0261-4189. PMID 12426395. 
  • Ofir-Rosenfeld, Yaara; Boggs Kristy, Michael Dan, Kastan Michael B, Oren Moshe (Oct. de 2008). «Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26». Mol. Cell (United States) 32 (2): 180-9. PMID 18951086. doi:10.1016/j.molcel.2008.08.031. 
  • Ochocka, Anna Maria; Kampanis Petros, Nicol Samantha, Allende-Vega Nerea, Cox Miranda, Marcar Lynnette, Milne Diane, Fuller-Pace Frances, Meek David (Feb. de 2009). «FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53». FEBS Lett. (Netherlands) 583 (4): 621-6. PMID 19166840. doi:10.1016/j.febslet.2009.01.009. 
  • Zhao, Lili; Samuels Tina, Winckler Sarah, Korgaonkar Chandrashekhar, Tompkins Van, Horne Mary C, Quelle Dawn E (Jan. de 2003). «Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways». Mol. Cancer Res. (United States) 1 (3): 195-206. ISSN 1541-7786. PMID 12556559. 
  • Legube, Gaëlle; Linares Laetitia K, Lemercier Claudie, Scheffner Martin, Khochbin Saadi, Trouche Didier (Apr. de 2002). «Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation». EMBO J. (England) 21 (7): 1704-12. ISSN 0261-4189. PMID 11927554. doi:10.1093/emboj/21.7.1704. 
  • Dai, Mu-Shui; Sun Xiao-Xin, Lu Hua (Jul. de 2008). «Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2». Mol. Cell. Biol. (United States) 28 (13): 4365-76. PMID 18426907. doi:10.1128/MCB.01662-07. 
  • Ivanchuk, Stacey M; Mondal Soma, Rutka James T (Jun. de 2008). «p14ARF interacts with DAXX: effects on HDM2 and p53». Cell Cycle (United States) 7 (12): 1836-50. PMID 18583933. 
  • Zhang, Zhuo; Zhang Ruiwen (Mar. de 2008). «Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation». EMBO J. (England) 27 (6): 852-64. PMID 18309296. doi:10.1038/emboj.2008.25. 
  • Sehat, Bita; Andersson Sandra, Girnita Leonard, Larsson Olle (Jul. de 2008). «Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis». Cancer Res. (United States) 68 (14): 5669-77. PMID 18632619. doi:10.1158/0008-5472.CAN-07-6364. 
  • Chang, Lufen; Zhou Bingsen, Hu Shuya, Guo Robin, Liu Xiyong, Jones Stephen N, Yen Yun (Nov. de 2008). «ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage». Proc. Natl. Acad. Sci. U.S.A. (United States) 105 (47): 18519-24. PMID 19015526. doi:10.1073/pnas.0803313105. 
  • Brenkman, Arjan B; de Keizer Peter L J, van den Broek Niels J F, Jochemsen A G, Burgering Boudewijn M Th (2008). «Mdm2 induces mono-ubiquitination of FOXO4». PLoS ONE (United States) 3 (7): e2819. PMID 18665269. doi:10.1371/journal.pone.0002819. 
  • Zhang, Yanping; Wolf Gabrielle White, Bhat Krishna, Jin Aiwen, Allio Theresa, Burkhart William A, Xiong Yue (Dec. de 2003). «Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway». Mol. Cell. Biol. (United States) 23 (23): 8902-12. ISSN 0270-7306. PMID 14612427. 
  • Marechal, V; Elenbaas B, Piette J, Nicolas J C, Levine A J (Nov. de 1994). «The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes». Mol. Cell. Biol. (UNITED STATES) 14 (11): 7414-20. ISSN 0270-7306. PMID 7935455. 
  • Goldberg, Zehavit; Vogt Sionov Ronit, Berger Michael, Zwang Yaara, Perets Ruth, Van Etten Richard A, Oren Moshe, Taya Yoichi, Haupt Ygal (Jul. de 2002). «Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation». EMBO J. (England) 21 (14): 3715-27. ISSN 0261-4189. PMID 12110584. doi:10.1093/emboj/cdf384. 
  • Chen, Deng; Zhang Jianbing, Li Mao, Rayburn Elizabeth R, Wang Hui, Zhang Ruiwen (Feb. de 2009). «RYBP stabilizes p53 by modulating MDM2». EMBO Rep. (England) 10 (2): 166-72. PMID 19098711. doi:10.1038/embor.2008.231. 
  • Chen, Delin; Li Muyang, Luo Jianyuan, Gu Wei (Apr. de 2003). «Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function». J. Biol. Chem. (United States) 278 (16): 13595-8. ISSN 0021-9258. PMID 12606552. doi:10.1074/jbc.C200694200. 
  • Ravi, R; Mookerjee B, Bhujwalla Z M, Sutter C H, Artemov D, Zeng Q, Dillehay L E, Madan A, Semenza G L, Bedi A (Jan. de 2000). «Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha». Genes Dev. (UNITED STATES) 14 (1): 34-44. ISSN 0890-9369. PMID 10640274. 
  • Jin, Yetao; Zeng Shelya X, Dai Mu-Shui, Yang Xiang-Jiao, Lu Hua (Aug. de 2002). «MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation». J. Biol. Chem. (United States) 277 (34): 30838-43. ISSN 0021-9258. PMID 12068014. doi:10.1074/jbc.M204078200. 
  • Léveillard, T; Wasylyk B (Dec. de 1997). «The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter». J. Biol. Chem. (UNITED STATES) 272 (49): 30651-61. ISSN 0021-9258. PMID 9388200. 
  • Thut, C J; Goodrich J A, Tjian R (Aug. de 1997). «Repression of p53-mediated transcription by MDM2: a dual mechanism». Genes Dev. (UNITED STATES) 11 (15): 1974-86. ISSN 0890-9369. PMID 9271120. 
  • Bálint, E; Bates S, Vousden K H (Jul. de 1999). «Mdm2 binds p73 alpha without targeting degradation». Oncogene (ENGLAND) 18 (27): 3923-9. ISSN 0950-9232. PMID 10435614. doi:10.1038/sj.onc.1202781. 
  • Zeng, X; Chen L, Jost C A, Maya R, Keller D, Wang X, Kaelin W G, Oren M, Chen J, Lu H (mayo. de 1999). «MDM2 suppresses p73 function without promoting p73 degradation». Mol. Cell. Biol. (UNITED STATES) 19 (5): 3257-66. ISSN 0270-7306. PMID 10207051. 
  • Mirnezami, Alexander H; Campbell Sandra J, Darley Matthew, Primrose John N, Johnson Peter W M, Blaydes Jeremy P (Jul. de 2003). «Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription». Curr. Biol. (England) 13 (14): 1234-9. ISSN 0960-9822. PMID 12867035. 
  • Yogosawa, Satomi; Miyauchi Yasuhiro, Honda Reiko, Tanaka Hirofumi, Yasuda Hideyo (Mar. de 2003). «Mammalian Numb is a target protein of Mdm2, ubiquitin ligase». Biochem. Biophys. Res. Commun. (United States) 302 (4): 869-72. ISSN 0006-291X. PMID 12646252. 
  • Colaluca, Ivan N; Tosoni Daniela, Nuciforo Paolo, Senic-Matuglia Francesca, Galimberti Viviana, Viale Giuseppe, Pece Salvatore, Di Fiore Pier Paolo (Jan. de 2008). «NUMB controls p53 tumour suppressor activity». Nature (England) 451 (7174): 76-80. PMID 18172499. doi:10.1038/nature06412. 
  • Haupt Y, Maya R, Kazaz A, Oren M (mayo de 1997). «Mdm2 promotes the rapid degradation of p53». Nature 387 (6630): 296-9. PMID 9153395. doi:10.1038/387296a0. 
  • Honda R, Tanaka H, Yasuda H (diciembre de 1997). «Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53». FEBS Lett. 420 (1): 25-7. PMID 9450543. 
  • Zhang Y, Xiong Y, Yarbrough WG (marzo de 1998). «ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways». Cell 92 (6): 725-34. PMID 9529249. 
  • Clark, Paula A; Llanos Susana, Peters Gordon (Jul. de 2002). «Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2». Oncogene (England) 21 (29): 4498-507. ISSN 0950-9232. PMID 12085228. doi:10.1038/sj.onc.1205558. 
  • Pomerantz, J; Schreiber-Agus N, Liégeois N J, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee H W, Cordon-Cardo C, DePinho R A (Mar. de 1998). «The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53». Cell (UNITED STATES) 92 (6): 713-23. ISSN 0092-8674. PMID 9529248. 
  • Okamoto, K; Li H; Jensen MR; Zhang T; Taya Y; Thorgeirsson SS; Prives C. (Apr. de 2002). «Cyclin G recruits PP2A to dephosphorylate Mdm2». Mol Cell (UNITED STATES) 9 (4): 761-71. PMID 11983168. 
  • Qiu W, Wu J, Walsh EM, et al. (julio de 2008). «Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells». Oncogene 27 (29): 4034-43. PMID 18332869. doi:10.1038/onc.2008.43. 
  • Grossman SR, Perez M, Kung AL, et al. (octubre de 1998). «p300/MDM2 complexes participate in MDM2-mediated p53 degradation». Mol. Cell 2 (4): 405-15. PMID 9809062. 
  • Kadakia, Madhavi; Brown Thomas L, McGorry Molly M, Berberich Steven J (Dec. de 2002). «MdmX inhibits Smad transactivation». Oncogene (England) 21 (57): 8776-85. ISSN 0950-9232. PMID 12483531. doi:10.1038/sj.onc.1205993. 
  • Tanimura, S; Ohtsuka S; Mitsui K; Shirouzu K; Yoshimura A; Ohtsubo M (Mar. de 1999). «MDM2 interacts with MDMX through their RING finger domains». FEBS Lett. (NETHERLANDS) 447 (1): 5-9. ISSN 0014-5793. PMID 10218570. 
  • Badciong, James C; Haas Arthur L (Dec. de 2002). «MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination». J. Biol. Chem. (United States) 277 (51): 49668-75. ISSN 0021-9258. PMID 12393902. doi:10.1074/jbc.M208593200. 
  • Linke, K; Mace P D, Smith C A, Vaux D L, Silke J, Day C L (mayo. de 2008). «Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans». Cell Death Differ. (England) 15 (5): 841-8. ISSN 1350-9047. PMID 18219319. doi:10.1038/sj.cdd.4402309. 
  • Bernardi, Rosa; Scaglioni Pier Paolo, Bergmann Stephan, Horn Henning F, Vousden Karen H, Pandolfi Pier Paolo (Jul. de 2004). «PML regulates p53 stability by sequestering Mdm2 to the nucleolus». Nat. Cell Biol. (England) 6 (7): 665-72. ISSN 1465-7392. PMID 15195100. doi:10.1038/ncb1147. 
  • Zhu, Hongyan; Wu Liqing, Maki Carl G (Dec. de 2003). «MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53». J. Biol. Chem. (United States) 278 (49): 49286-92. ISSN 0021-9258. PMID 14507915. doi:10.1074/jbc.M308302200. 
  • Kurki S, Latonen L, Laiho M (octubre de 2003). «Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization». J. Cell. Sci. 116 (Pt 19): 3917-25. PMID 12915590. doi:10.1242/jcs.00714. 
  • Wei, Xiaolong; Yu Zhong Kang, Ramalingam Arivudainambi, Grossman Steven R, Yu Jiang H, Bloch Donald B, Maki Carl G (Aug. de 2003). «Physical and functional interactions between PML and MDM2». J. Biol. Chem. (United States) 278 (31): 29288-97. ISSN 0021-9258. PMID 12759344. doi:10.1074/jbc.M212215200. 
  • Maguire, Maria; Nield Paul C, Devling Timothy, Jenkins Rosalind E, Park B Kevin, Polański Radoslaw, Vlatković Nikolina, Boyd Mark T (mayo. de 2008). «MDM2 regulates dihydrofolate reductase activity through monoubiquitination». Cancer Res. (United States) 68 (9): 3232-42. PMID 18451149. doi:10.1158/0008-5472.CAN-07-5271. 
  • Wang, Ping; Gao Hua, Ni Yanxiang, Wang Beibei, Wu Yalan, Ji Lili, Qin Linhua, Ma Lan, Pei Gang (Feb. de 2003). «Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2». J. Biol. Chem. (United States) 278 (8): 6363-70. ISSN 0021-9258. PMID 12488444. doi:10.1074/jbc.M210350200. 
  • Wang, Ping; Wu Yalan, Ge Xin, Ma Lan, Pei Gang (Mar. de 2003). «Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus». J. Biol. Chem. (United States) 278 (13): 11648-53. ISSN 0021-9258. PMID 12538596. doi:10.1074/jbc.M208109200. 
  • Shenoy, Sudha K; Xiao Kunhong, Venkataramanan Vidya, Snyder Peter M, Freedman Neil J, Weissman Allan M (Aug. de 2008). «Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor». J. Biol. Chem. (United States) 283 (32): 22166-76. ISSN 0021-9258. PMID 18544533. doi:10.1074/jbc.M709668200. 
  • Song, Min Sup; Song Su Jung, Kim So Yeon, Oh Hyun Jung, Lim Dae-Sik (Jul. de 2008). «The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex». EMBO J. (England) 27 (13): 1863-74. PMID 18566590. doi:10.1038/emboj.2008.115. 
  • Yang, Wensheng; Dicker David T, Chen Jiandong, El-Deiry Wafik S (Mar. de 2008). «CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2». Cell Cycle (United States) 7 (5): 670-82. PMID 18382127.