«Opportunities and challenges in phenotypic drug discovery: an industry perspective». Nature Reviews. Drug Discovery16 (8): 531-543. 2017. PMID28685762. doi:10.1038/nrd.2017.111. «Novelty of target and MoA [Mechanism of Action] is the second major potential advantage of PDD [Phenotypic Drug Discovery]. In addition to identifying novel targets, PDD can contribute to improvements over existing therapies by identifying novel physiology for a known target, exploring ‘undrugged’ targets that belong to well known drug target classes or discovering novel MoAs, including new ways of interfering with difficult-to-drug targets.»
«Target identification for biologically active small molecules using chemical biology approaches». Archives of Pharmacal Research39 (9): 1193-201. 2016. PMID27387321. doi:10.1007/s12272-016-0791-z.
«Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery». Archives of Pharmacal Research38 (9): 1627-41. 2015. PMID26040984. doi:10.1007/s12272-015-0618-3.
«Evolutionary conservation of human drug targets in organisms used for environmental risk assessments». Environmental Science & Technology42 (15): 5807-5813. August 2008. PMID18754513. doi:10.1021/es8005173.
«Ethinyloestradiol — an undesired fish contraceptive?». Aquatic Toxicology45 (2–3): 91-97. April 1999. doi:10.1016/S0166-445X(98)00112-X.
«Repeating history: pharmaceuticals in the environment». Environmental Science & Technology41 (24): 8211-7. 2007. PMID18200843. doi:10.1021/es072658j.
«Opportunities and challenges in phenotypic drug discovery: an industry perspective». Nature Reviews. Drug Discovery16 (8): 531-543. 2017. PMID28685762. doi:10.1038/nrd.2017.111. «Novelty of target and MoA [Mechanism of Action] is the second major potential advantage of PDD [Phenotypic Drug Discovery]. In addition to identifying novel targets, PDD can contribute to improvements over existing therapies by identifying novel physiology for a known target, exploring ‘undrugged’ targets that belong to well known drug target classes or discovering novel MoAs, including new ways of interfering with difficult-to-drug targets.»
«Target identification for biologically active small molecules using chemical biology approaches». Archives of Pharmacal Research39 (9): 1193-201. 2016. PMID27387321. doi:10.1007/s12272-016-0791-z.
«Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery». Archives of Pharmacal Research38 (9): 1627-41. 2015. PMID26040984. doi:10.1007/s12272-015-0618-3.
«Evolutionary conservation of human drug targets in organisms used for environmental risk assessments». Environmental Science & Technology42 (15): 5807-5813. August 2008. PMID18754513. doi:10.1021/es8005173.
«Repeating history: pharmaceuticals in the environment». Environmental Science & Technology41 (24): 8211-7. 2007. PMID18200843. doi:10.1021/es072658j.