Baumann, Christian R.; Bassetti, Claudio L. (Agosto de 2005). «Hypocretins (orexins): clinical impact of the discovery of a neurotransmitter». Sleep Medicine Reviews9 (4): 253-268. doi:10.1016/j.smrv.2005.01.005.
Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE (julio de 2004). «Behavioral state instability in orexin knock-out mice». J. Neurosci.24 (28): 6291-300. PMID15254084. doi:10.1523/JNEUROSCI.0586-04.2004.
Deadwyler SA, Porrino L, Siegel JM, Hampson RE (2007). «Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates». J. Neurosci.27 (52): 14239-47. PMID18160631. doi:10.1523/JNEUROSCI.3878-07.2007.
Hallmayer J, Faraco J, Lin L, et al. (junio de 2009). «Narcolepsy is strongly associated with the T-cell receptor alpha locus». Nat. Genet.41 (6): 708-11. PMID19412176. doi:10.1038/ng.372.
J. E. Kang, M. M. Lim, R. J. Bateman, J. J. Lee, L. P. Smyth, J. R. Cirrito, N. Fujiki, S. Nishino and D. M. Holtzman (2009). «Amyloid-{beta} Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle». Science. doi:10.1126/science.1180962.
Acuna-Goycolea C, Li Y, Van Den Pol AN (marzo de 2004). «Group III metabotropic glutamate receptors maintain tonic inhibition of excitatory synaptic input to hypocretin/orexin neurons». J. Neurosci.24 (12): 3013-22. PMID15044540. doi:10.1523/JNEUROSCI.5416-03.2004.
Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T (agosto de 2004). «Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor». J. Neurosci.24 (32): 7159-66. PMID15306649. doi:10.1523/JNEUROSCI.1027-04.2004.
Fu LY, Acuna-Goycolea C, van den Pol AN (octubre de 2004). «Neuropeptide Y inhibits hypocretin/orexin neurons by múltiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system». J. Neurosci.24 (40): 8741-51. PMID15470140. doi:10.1523/JNEUROSCI.2268-04.2004.
Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T (agosto de 2005). «Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor». J. Neurosci.25 (32): 7459-69. PMID16093397. doi:10.1523/JNEUROSCI.1193-05.2005.
Li Y, van den Pol AN (enero de 2005). «Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons». J. Neurosci.25 (1): 173-83. PMID15634779. doi:10.1523/JNEUROSCI.4015-04.2005.
Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T (julio de 2006). «Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner». J. Neurophysiol.96 (1): 284-98. PMID16611835. doi:10.1152/jn.01361.2005.
Ohno K, Sakurai T (enero de 2008). «Orexin neuronal circuitry: role in the regulation of sleep and wakefulness». Front Neuroendocrinol29 (1): 70-87. PMID17910982. doi:10.1016/j.yfrne.2007.08.001.
Bernard R, Lydic R, Baghdoyan HA (octubre de 2003). «Hypocretin-1 causes G protein activation and increases ACh release in rat pons». Eur. J. Neurosci.18 (7): 1775-85. PMID14622212. doi:10.1046/j.1460-9568.2003.02905.x.
Soffin EM, Gill CH, Brough SJ, Jerman JC, Davies CH (junio de 2004). «Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus». Neuropharmacology46 (8): 1168-76. PMID15111023. doi:10.1016/j.neuropharm.2004.02.014.
Lin L, Faraco J, et. al. (1999). «The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene.». Cell98 (3): 365-376. PMID10458611.
Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE (julio de 2004). «Behavioral state instability in orexin knock-out mice». J. Neurosci.24 (28): 6291-300. PMID15254084. doi:10.1523/JNEUROSCI.0586-04.2004.
Deadwyler SA, Porrino L, Siegel JM, Hampson RE (2007). «Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates». J. Neurosci.27 (52): 14239-47. PMID18160631. doi:10.1523/JNEUROSCI.3878-07.2007.
Klein J, Sato A (septiembre de 2000). «The HLA system. Second of two parts». N. Engl. J. Med.343 (11): 782-6. PMID10984567.
Hallmayer J, Faraco J, Lin L, et al. (junio de 2009). «Narcolepsy is strongly associated with the T-cell receptor alpha locus». Nat. Genet.41 (6): 708-11. PMID19412176. doi:10.1038/ng.372.
Gautvik KM, de Lecea L, et. al. (1996). «Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction.». PNAS93 (16): 8733-8738. PMID8710940.
Acuna-Goycolea C, Li Y, Van Den Pol AN (marzo de 2004). «Group III metabotropic glutamate receptors maintain tonic inhibition of excitatory synaptic input to hypocretin/orexin neurons». J. Neurosci.24 (12): 3013-22. PMID15044540. doi:10.1523/JNEUROSCI.5416-03.2004.
Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T (agosto de 2004). «Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor». J. Neurosci.24 (32): 7159-66. PMID15306649. doi:10.1523/JNEUROSCI.1027-04.2004.
Fu LY, Acuna-Goycolea C, van den Pol AN (octubre de 2004). «Neuropeptide Y inhibits hypocretin/orexin neurons by múltiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system». J. Neurosci.24 (40): 8741-51. PMID15470140. doi:10.1523/JNEUROSCI.2268-04.2004.
Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T (agosto de 2005). «Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor». J. Neurosci.25 (32): 7459-69. PMID16093397. doi:10.1523/JNEUROSCI.1193-05.2005.
Li Y, van den Pol AN (enero de 2005). «Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons». J. Neurosci.25 (1): 173-83. PMID15634779. doi:10.1523/JNEUROSCI.4015-04.2005.
Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T (julio de 2006). «Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner». J. Neurophysiol.96 (1): 284-98. PMID16611835. doi:10.1152/jn.01361.2005.
Ohno K, Sakurai T (enero de 2008). «Orexin neuronal circuitry: role in the regulation of sleep and wakefulness». Front Neuroendocrinol29 (1): 70-87. PMID17910982. doi:10.1016/j.yfrne.2007.08.001.
Bernard R, Lydic R, Baghdoyan HA (octubre de 2003). «Hypocretin-1 causes G protein activation and increases ACh release in rat pons». Eur. J. Neurosci.18 (7): 1775-85. PMID14622212. doi:10.1046/j.1460-9568.2003.02905.x.
Soffin EM, Gill CH, Brough SJ, Jerman JC, Davies CH (junio de 2004). «Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus». Neuropharmacology46 (8): 1168-76. PMID15111023. doi:10.1016/j.neuropharm.2004.02.014.
Nishino, Seiji; Sakurai, Takeshi (2006). «History and Overview of Orexin/Hypocretin Research»(PDF [extracto de capítulo]). The orexin/hypocretin system physiology and pathophysiology. Totowa, N.J: Humana Press. p. 3. ISBN978-1-59259-950-9. Consultado el 21 de abril de 2018. «Because these predicted peptides were expressed in the hypothalamus and had similarity to secretin, they named them hypocretin-1 and -2».