National Industrial Chemicals Notification And Assesment Scheme – Full Public Report:SPLENDA/SUCRALOSE (PDF) (”The notified chemical was not teratogenic or neurotoxic and had no effect on reproduction, insulin secretion and carbohydrate metabolism. Sucralose was found to induce a reduction in thymus weight in rats dosed orally with 3000 mg/kg bw/day.”) industrialchemicals.gov.au. 2003. Viitattu 10.11.2023.
nih.gov
ncbi.nlm.nih.gov
Sasaki YF ym.: The comet assay with 8 mouse organs: results with 39 currently used food additives. (”Among the five tested sweeteners, sodium cyclamate induced a statistically significant DNA damage increase in the glandular stomach, colon, kidney, and urinary bladder, saccharin in the colon, sodium saccharin in the glandular stomach and colon, and sucralose in the glandular stomach, colon, and lung. The lowest dose that induced DNA damage was 1 000 mg/kg for saccharin and its sodium salt and 2 000 mg/kg for sodium cyclamate and sucralose.”) Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Määritä ajankohta!Artikkelin verkkoversio.