Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH, « Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 », Immunity, vol. 3, no 5, , p. 541–7 (PMID7584144, DOI10.1016/1074-7613(95)90125-6, lire en ligne)
doi.org
dx.doi.org
(en) Nicholas L Syn, Michele W L Teng, Tony S K Mok et Ross A Soo, « De-novo and acquired resistance to immune checkpoint targeting », The Lancet Oncology, vol. 18, no 12, , e731–e741 (PMID29208439, DOI10.1016/s1470-2045(17)30607-1, lire en ligne)
Brunet JF, Denizot F, Luciani MF, Roux-Dosseto M, Suzan M, Mattei MG, Golstein P, « A new member of the immunoglobulin superfamily--CTLA-4 », Nature, vol. 328, no 6127, , p. 267–70 (PMID3496540, DOI10.1038/328267a0)
Dariavach P, Mattéi MG, Golstein P, Lefranc MP, « Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains », Eur. J. Immunol., vol. 18, no 12, , p. 1901–5 (PMID3220103, DOI10.1002/eji.1830181206)
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW, « Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 », Science, vol. 270, no 5238, , p. 985–8 (PMID7481803, DOI10.1126/science.270.5238.985, JSTOR2888113)
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH, « Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 », Immunity, vol. 3, no 5, , p. 541–7 (PMID7584144, DOI10.1016/1074-7613(95)90125-6, lire en ligne)
Krummel MF, Allison JP, « CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation », J. Exp. Med., vol. 182, no 2, , p. 459–65 (PMID7543139, PMCID2192127, DOI10.1084/jem.182.2.459)
Walunas TL, Bakker CY, Bluestone JA, « CTLA-4 ligation blocks CD28-dependent T cell activation », J. Exp. Med., vol. 183, no 6, , p. 2541–50 (PMID8676075, PMCID2192609, DOI10.1084/jem.183.6.2541)
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA, « CTLA-4 can function as a negative regulator of T cell activation », Immunity, vol. 1, no 5, , p. 405–13 (PMID7882171, DOI10.1016/1074-7613(94)90071-x)
Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP, « CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones », Nature, vol. 356, no 6370, , p. 607–9 (PMID1313950, DOI10.1038/356607a0)
Magistrelli G, Jeannin P, Herbault N, Benoit De Coignac A, Gauchat JF, Bonnefoy JY, Delneste Y, « A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells », Eur. J. Immunol., vol. 29, no 11, , p. 3596–602 (PMID10556814, DOI10.1002/(SICI)1521-4141(199911)29:11<3596::AID-IMMU3596>3.0.CO;2-Y)
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA, « Molecular basis of T cell inactivation by CTLA-4 », Science, vol. 282, no 5397, , p. 2263–6 (PMID9856951, DOI10.1126/science.282.5397.2263)
Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, Baker J, Jeffery LE, Kaur S, Briggs Z, Hou TZ, Futter CE, Anderson G, Walker LS, Sansom DM, « Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4 », Science, vol. 332, no 6029, , p. 600–3 (PMID21474713, PMCID3198051, DOI10.1126/science.1202947)
Chen J, Ganguly A, Mucsi AD, Meng J, Yan J, Detampel P, Munro F, Zhang Z, Wu M, Hari A, Stenner MD, Zheng W, Kubes P, Xia T, Amrein MW, Qi H, Shi Y, « Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy », The Journal of Experimental Medicine, vol. 214, no 2, , p. 327–338 (PMID28082358, PMCID5294852, DOI10.1084/jem.20160620)
elsevier.com
linkinghub.elsevier.com
(en) Nicholas L Syn, Michele W L Teng, Tony S K Mok et Ross A Soo, « De-novo and acquired resistance to immune checkpoint targeting », The Lancet Oncology, vol. 18, no 12, , e731–e741 (PMID29208439, DOI10.1016/s1470-2045(17)30607-1, lire en ligne)
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW, « Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 », Science, vol. 270, no 5238, , p. 985–8 (PMID7481803, DOI10.1126/science.270.5238.985, JSTOR2888113)
(en) Nicholas L Syn, Michele W L Teng, Tony S K Mok et Ross A Soo, « De-novo and acquired resistance to immune checkpoint targeting », The Lancet Oncology, vol. 18, no 12, , e731–e741 (PMID29208439, DOI10.1016/s1470-2045(17)30607-1, lire en ligne)
Brunet JF, Denizot F, Luciani MF, Roux-Dosseto M, Suzan M, Mattei MG, Golstein P, « A new member of the immunoglobulin superfamily--CTLA-4 », Nature, vol. 328, no 6127, , p. 267–70 (PMID3496540, DOI10.1038/328267a0)
Dariavach P, Mattéi MG, Golstein P, Lefranc MP, « Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains », Eur. J. Immunol., vol. 18, no 12, , p. 1901–5 (PMID3220103, DOI10.1002/eji.1830181206)
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW, « Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 », Science, vol. 270, no 5238, , p. 985–8 (PMID7481803, DOI10.1126/science.270.5238.985, JSTOR2888113)
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH, « Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 », Immunity, vol. 3, no 5, , p. 541–7 (PMID7584144, DOI10.1016/1074-7613(95)90125-6, lire en ligne)
Krummel MF, Allison JP, « CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation », J. Exp. Med., vol. 182, no 2, , p. 459–65 (PMID7543139, PMCID2192127, DOI10.1084/jem.182.2.459)
Walunas TL, Bakker CY, Bluestone JA, « CTLA-4 ligation blocks CD28-dependent T cell activation », J. Exp. Med., vol. 183, no 6, , p. 2541–50 (PMID8676075, PMCID2192609, DOI10.1084/jem.183.6.2541)
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA, « CTLA-4 can function as a negative regulator of T cell activation », Immunity, vol. 1, no 5, , p. 405–13 (PMID7882171, DOI10.1016/1074-7613(94)90071-x)
Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP, « CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones », Nature, vol. 356, no 6370, , p. 607–9 (PMID1313950, DOI10.1038/356607a0)
Magistrelli G, Jeannin P, Herbault N, Benoit De Coignac A, Gauchat JF, Bonnefoy JY, Delneste Y, « A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells », Eur. J. Immunol., vol. 29, no 11, , p. 3596–602 (PMID10556814, DOI10.1002/(SICI)1521-4141(199911)29:11<3596::AID-IMMU3596>3.0.CO;2-Y)
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA, « Molecular basis of T cell inactivation by CTLA-4 », Science, vol. 282, no 5397, , p. 2263–6 (PMID9856951, DOI10.1126/science.282.5397.2263)
Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, Baker J, Jeffery LE, Kaur S, Briggs Z, Hou TZ, Futter CE, Anderson G, Walker LS, Sansom DM, « Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4 », Science, vol. 332, no 6029, , p. 600–3 (PMID21474713, PMCID3198051, DOI10.1126/science.1202947)
Chen J, Ganguly A, Mucsi AD, Meng J, Yan J, Detampel P, Munro F, Zhang Z, Wu M, Hari A, Stenner MD, Zheng W, Kubes P, Xia T, Amrein MW, Qi H, Shi Y, « Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy », The Journal of Experimental Medicine, vol. 214, no 2, , p. 327–338 (PMID28082358, PMCID5294852, DOI10.1084/jem.20160620)