(en) « What We Know Today About Alzheimer's Disease », Alzheimer's Association (consulté le ) : « While scientists know Alzheimer's disease involves progressive brain cell failure, the reason cells fail isn't clear. »
alzheimer-adna.com
LA TRISOMIE 21, sur le site alzheimer-adna.com du 21 mars 2006.
(en) Selkoe DJ, « Translating cell biology into therapeutic advances in Alzheimer's disease », Nature, vol. 399, no 6738 Suppl, , A23–31. (PMID10392577, DOI10.1038/19866)
(en) Borchelt DR, Thinakaran G, Eckman CB, Michael K. Levey, Frances Gandy, Tamara Copeland, Cristian-Mihail Jenkins, Grace Price et Sophia Younkin, « Familial Alzheimer's disease-linked presenilin 1 variants elevate βA1-42/1-40 ratio in vitro and in vivo », Neuron, vol. 17, no 5, , p. 1005–1013. (PMID8938131, DOI10.1016/S0896-6273(00)80230-5)
(en) Shioi J, Georgakopoulos A, Mehta P, Zen Kouchi, Claudia M. Litterst, Lia Baki et Nikolaos K. Robakis, « FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta », J Neurochem, vol. 101, no 3, , p. 674–681. (PMID17254019, DOI10.1111/j.1471-4159.2006.04391.x)
(en) Strittmatter WJ, Saunders AM, Schmechel D, M Pericak-Vance, J Enghild, GS Salvesen et AD Roses, « Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease », Proc. Natl. Acad. Sci. USA, vol. 90, no 5, , p. 1977–1981. (PMID8446617, PMCID46003, DOI10.1073/pnas.90.5.1977)
(en) Mahley RW, Weisgraber KH, Huang Y, « Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease », Proc. Natl. Acad. Sci. U.S.A., vol. 103, no 15, , p. 5644–5651. (PMID16567625, PMCID1414631, DOI10.1073/pnas.0600549103)
(en) Hall K, Murrell J, Ogunniyi A, Deeg M, Baiyewu O, Gao S, Gureje O, Dickens J, Evans R, Smith-Gamble V, Unverzagt FW, Shen J, Hendrie H, « Cholesterol, APOE genotype, and Alzheimer disease: An epidemiologic study of Nigerian Yoruba », Neurology, vol. 66, no 2, , p. 223–227. (PMID16434658, PMCID2860622, DOI10.1212/01.wnl.0000194507.39504.17, lire en ligne)
(en) Gureje O, Ogunniyi A, Baiyewu O, Price B, Unverzagt FW, Evans RM, Smith-Gamble V, Lane KA, Gao S, Hall KS, Hendrie HC, Murrell JR, « APOE ε4 Is Not Associated with Alzheimer's Disease in Elderly Nigerians », Ann Neurol, vol. 59, no 1, , p. 182–185. (PMID16278853, PMCID2855121, DOI10.1002/ana.20694, lire en ligne)
(en) R. Guerreiro, A. Wojtas, J. Bras et al., « TREM2 variants in Alzheimer's disease », N Engl J Med., vol. 368, , p. 117-127 (DOI10.1056/NEJMoa1211851)
(en) K. Takahashi, C.D. Rochford et H. Neumann, « Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2 », J Exp Med., vol. 201, , p. 647-657 (DOI10.1084/jem.20041611)
J. Hardy et D. Allsop, « Amyloid Deposition as the Central Event in the Aetiology of Alzheimer's Disease », Trends in Pharmacological Sciences, vol. 12, no 10, , p. 383–88 (PMID1763432, DOI10.1016/0165-6147(91)90609-V)
A. Mudher et S. Lovestone, « Alzheimer's disease-do tauists and baptists finally shake hands? », Trends in Neurosciences, vol. 25, no 1, , p. 22–26 (PMID11801334, DOI10.1016/S0166-2236(00)02031-2)
M. Nistor, M. Don, M. Parekhet al., « Alpha- and Beta-secretase Activity as a Function of Age and Beta-amyloid in Down Syndrome and Normal Brain », Neurobiology of Aging, vol. 28, no 10, , p. 1493–506 (PMID16904243, PMCID3375834, DOI10.1016/j.neurobiolaging.2006.06.023)
T. Polvikoski, R. Sulkava, M. Haltiaet al., « Apolipoprotein E, Dementia, and Cortical Deposition of Beta-amyloid Protein », The New England Journal of Medicine, vol. 333, no 19, , p. 1242–47 (PMID7566000, DOI10.1056/NEJM199511093331902)
Transgenic mice:
D. Games, D. Adams, R. Alessandriniet al., « Alzheimer-type Neuropathology in Transgenic Mice Overexpressing V717F Beta-amyloid Precursor Protein », Nature, vol. 373, no 6514, , p. 523–27 (PMID7845465, DOI10.1038/373523a0)
C. Holmes, D. Boche, D. Wilkinsonet al., « Long-term Effects of Abeta42 Immunisation in Alzheimer's Disease: Follow-up of a Randomised, Placebo-controlled Phase I Trial », Lancet, vol. 372, no 9634, , p. 216–23 (PMID18640458, DOI10.1016/S0140-6736(08)61075-2)
(en) Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, Lövheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA, « Microbes and Alzheimer’s Disease », Journal of Alzheimer's Disease, vol. 51, no 4, , p. 979-984 (PMID26967229, DOI10.3233/JAD-160152, lire en ligne),
(en) Diana Pisa, Ruth Alonso, Alberto Rábano, Izaskun Rodal et Luis Carrasco, « Different Brain Regions are Infected with Fungi in Alzheimer's Disease », Nature Scientific Reports, (PMID26468932, DOI10.1038/srep15015, lire en ligne)
(en) R. Alonso, D. Pisa, A. Rábano et L. Carrasco, « Alzheimer's disease and disseminated mycoses. », European Journal of Clinical Microbiology & Infectious Diseases, vol. 33, no 7, (PMID24452965, DOI10.1007/s10096-013-2045-z)
(en) Jennifer Weuve, Jennifer D'Souza, Todd Beck et Denis A. Evans, « Long‐term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults », Alzheimer's & Dementia, , alz.12191 (ISSN1552-5260 et 1552-5279, DOI10.1002/alz.12191, lire en ligne, consulté le )
(en) Cairns, Dana M., Itzhaki, Ruth F., Kaplan, David L., « Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1 », Journal of Alzheimer's Disease, IOS Press (d), (ISSN1387-2877 et 1875-8908, OCLC41219744, PMID35754275, DOI10.3233/JAD-220287).
(en) Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, Lövheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA, « Microbes and Alzheimer’s Disease », Journal of Alzheimer's Disease, vol. 51, no 4, , p. 979-984 (PMID26967229, DOI10.3233/JAD-160152, lire en ligne),
issn.org
portal.issn.org
(en) Jennifer Weuve, Jennifer D'Souza, Todd Beck et Denis A. Evans, « Long‐term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults », Alzheimer's & Dementia, , alz.12191 (ISSN1552-5260 et 1552-5279, DOI10.1002/alz.12191, lire en ligne, consulté le )
(en) Itzhaki RF, Wozniak MA, « Herpes Simplex Virus Type 1 in Alzheimer's Disease: The Enemy Within », Journal of Alzheimer's Disease, vol. 13, no 4, , p. 393–405 (ISSN1387-2877, PMID18487848, lire en ligne, consulté le )
(en) Cairns, Dana M., Itzhaki, Ruth F., Kaplan, David L., « Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1 », Journal of Alzheimer's Disease, IOS Press (d), (ISSN1387-2877 et 1875-8908, OCLC41219744, PMID35754275, DOI10.3233/JAD-220287).
(en) Itzhaki RF, Wozniak MA, « Herpes Simplex Virus Type 1 in Alzheimer's Disease: The Enemy Within », Journal of Alzheimer's Disease, vol. 13, no 4, , p. 393–405 (ISSN1387-2877, PMID18487848, lire en ligne, consulté le )
nature.com
(en) J.-C. Lambert et al. « Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease » Nature Genetics vol. 41, p. 1094-1099, 2009 (Résumé).
(en) D. Harold et al. « Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease » Nature Genetics vol. 41, p. 1088-1093, 2009 (Résumé).
(en) Diana Pisa, Ruth Alonso, Alberto Rábano, Izaskun Rodal et Luis Carrasco, « Different Brain Regions are Infected with Fungi in Alzheimer's Disease », Nature Scientific Reports, (PMID26468932, DOI10.1038/srep15015, lire en ligne)
nejm.org
(en) T. Jonsson, H. Stefansson, S. Steinberg et al., « Variant of TREM2 associated with the risk of Alzheimer's disease », N Engl J Med., vol. 368, , p. 107-116 (lire en ligne)
(en) H. Neumann et M.J. Daly, « Variant TREM2 as risk factor for Alzheimer's disease », N Engl J Med., vol. 368, , p. 182-184 (résumé)
(en) Selkoe DJ, « Translating cell biology into therapeutic advances in Alzheimer's disease », Nature, vol. 399, no 6738 Suppl, , A23–31. (PMID10392577, DOI10.1038/19866)
(en) Borchelt DR, Thinakaran G, Eckman CB, Michael K. Levey, Frances Gandy, Tamara Copeland, Cristian-Mihail Jenkins, Grace Price et Sophia Younkin, « Familial Alzheimer's disease-linked presenilin 1 variants elevate βA1-42/1-40 ratio in vitro and in vivo », Neuron, vol. 17, no 5, , p. 1005–1013. (PMID8938131, DOI10.1016/S0896-6273(00)80230-5)
(en) Shioi J, Georgakopoulos A, Mehta P, Zen Kouchi, Claudia M. Litterst, Lia Baki et Nikolaos K. Robakis, « FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta », J Neurochem, vol. 101, no 3, , p. 674–681. (PMID17254019, DOI10.1111/j.1471-4159.2006.04391.x)
(en) Strittmatter WJ, Saunders AM, Schmechel D, M Pericak-Vance, J Enghild, GS Salvesen et AD Roses, « Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease », Proc. Natl. Acad. Sci. USA, vol. 90, no 5, , p. 1977–1981. (PMID8446617, PMCID46003, DOI10.1073/pnas.90.5.1977)
(en) Mahley RW, Weisgraber KH, Huang Y, « Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease », Proc. Natl. Acad. Sci. U.S.A., vol. 103, no 15, , p. 5644–5651. (PMID16567625, PMCID1414631, DOI10.1073/pnas.0600549103)
(en) Hall K, Murrell J, Ogunniyi A, Deeg M, Baiyewu O, Gao S, Gureje O, Dickens J, Evans R, Smith-Gamble V, Unverzagt FW, Shen J, Hendrie H, « Cholesterol, APOE genotype, and Alzheimer disease: An epidemiologic study of Nigerian Yoruba », Neurology, vol. 66, no 2, , p. 223–227. (PMID16434658, PMCID2860622, DOI10.1212/01.wnl.0000194507.39504.17, lire en ligne)
(en) Gureje O, Ogunniyi A, Baiyewu O, Price B, Unverzagt FW, Evans RM, Smith-Gamble V, Lane KA, Gao S, Hall KS, Hendrie HC, Murrell JR, « APOE ε4 Is Not Associated with Alzheimer's Disease in Elderly Nigerians », Ann Neurol, vol. 59, no 1, , p. 182–185. (PMID16278853, PMCID2855121, DOI10.1002/ana.20694, lire en ligne)
J. Hardy et D. Allsop, « Amyloid Deposition as the Central Event in the Aetiology of Alzheimer's Disease », Trends in Pharmacological Sciences, vol. 12, no 10, , p. 383–88 (PMID1763432, DOI10.1016/0165-6147(91)90609-V)
A. Mudher et S. Lovestone, « Alzheimer's disease-do tauists and baptists finally shake hands? », Trends in Neurosciences, vol. 25, no 1, , p. 22–26 (PMID11801334, DOI10.1016/S0166-2236(00)02031-2)
M. Nistor, M. Don, M. Parekhet al., « Alpha- and Beta-secretase Activity as a Function of Age and Beta-amyloid in Down Syndrome and Normal Brain », Neurobiology of Aging, vol. 28, no 10, , p. 1493–506 (PMID16904243, PMCID3375834, DOI10.1016/j.neurobiolaging.2006.06.023)
T. Polvikoski, R. Sulkava, M. Haltiaet al., « Apolipoprotein E, Dementia, and Cortical Deposition of Beta-amyloid Protein », The New England Journal of Medicine, vol. 333, no 19, , p. 1242–47 (PMID7566000, DOI10.1056/NEJM199511093331902)
Transgenic mice:
D. Games, D. Adams, R. Alessandriniet al., « Alzheimer-type Neuropathology in Transgenic Mice Overexpressing V717F Beta-amyloid Precursor Protein », Nature, vol. 373, no 6514, , p. 523–27 (PMID7845465, DOI10.1038/373523a0)
C. Holmes, D. Boche, D. Wilkinsonet al., « Long-term Effects of Abeta42 Immunisation in Alzheimer's Disease: Follow-up of a Randomised, Placebo-controlled Phase I Trial », Lancet, vol. 372, no 9634, , p. 216–23 (PMID18640458, DOI10.1016/S0140-6736(08)61075-2)
(en) Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, Lövheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA, « Microbes and Alzheimer’s Disease », Journal of Alzheimer's Disease, vol. 51, no 4, , p. 979-984 (PMID26967229, DOI10.3233/JAD-160152, lire en ligne),
(en) Diana Pisa, Ruth Alonso, Alberto Rábano, Izaskun Rodal et Luis Carrasco, « Different Brain Regions are Infected with Fungi in Alzheimer's Disease », Nature Scientific Reports, (PMID26468932, DOI10.1038/srep15015, lire en ligne)
(en) R. Alonso, D. Pisa, A. Rábano et L. Carrasco, « Alzheimer's disease and disseminated mycoses. », European Journal of Clinical Microbiology & Infectious Diseases, vol. 33, no 7, (PMID24452965, DOI10.1007/s10096-013-2045-z)
(en) Itzhaki RF, Wozniak MA, « Herpes Simplex Virus Type 1 in Alzheimer's Disease: The Enemy Within », Journal of Alzheimer's Disease, vol. 13, no 4, , p. 393–405 (ISSN1387-2877, PMID18487848, lire en ligne, consulté le )
(en) Cairns, Dana M., Itzhaki, Ruth F., Kaplan, David L., « Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1 », Journal of Alzheimer's Disease, IOS Press (d), (ISSN1387-2877 et 1875-8908, OCLC41219744, PMID35754275, DOI10.3233/JAD-220287).
(en) de la Monte SM, Wands JR, « Alzheimer's disease is type 3 diabetes-evidence reviewed », J Diabetes Sci Technol, vol. 2, no 6, , p. 1101-13. (PMID19885299, PMCIDPMC2769828, lire en ligne [PDF])modifier
sagepub.com
dst.sagepub.com
(en) de la Monte SM, Wands JR, « Alzheimer's disease is type 3 diabetes-evidence reviewed », J Diabetes Sci Technol, vol. 2, no 6, , p. 1101-13. (PMID19885299, PMCIDPMC2769828, lire en ligne [PDF])modifier
(en) Cairns, Dana M., Itzhaki, Ruth F., Kaplan, David L., « Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1 », Journal of Alzheimer's Disease, IOS Press (d), (ISSN1387-2877 et 1875-8908, OCLC41219744, PMID35754275, DOI10.3233/JAD-220287).
wikipedia.org
fr.wikipedia.org
(en) de la Monte SM, Wands JR, « Alzheimer's disease is type 3 diabetes-evidence reviewed », J Diabetes Sci Technol, vol. 2, no 6, , p. 1101-13. (PMID19885299, PMCIDPMC2769828, lire en ligne [PDF])modifier
wiley.com
onlinelibrary.wiley.com
(en) Jennifer Weuve, Jennifer D'Souza, Todd Beck et Denis A. Evans, « Long‐term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults », Alzheimer's & Dementia, , alz.12191 (ISSN1552-5260 et 1552-5279, DOI10.1002/alz.12191, lire en ligne, consulté le )
worldcat.org
(en) Cairns, Dana M., Itzhaki, Ruth F., Kaplan, David L., « Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1 », Journal of Alzheimer's Disease, IOS Press (d), (ISSN1387-2877 et 1875-8908, OCLC41219744, PMID35754275, DOI10.3233/JAD-220287).