« Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor », The Journal of Pharmacology and Experimental Therapeutics, vol. 283, no 2, , p. 636–47 (PMID9353380, lire en ligne)
« S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride », The Journal of Pharmacology and Experimental Therapeutics, vol. 287, no 1, , p. 167–86 (PMID9765336, lire en ligne)
molpharm.aspetjournals.org
« Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor », Molecular Pharmacology, vol. 50, no 6, , p. 1658–64 (PMID8967990, lire en ligne)
« Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders », Medical Science Monitor, vol. 17, no 9, , RA215–20 (PMID21873960, PMCID3560519, DOI10.12659/MSM.881925)
« Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder », Molecular Psychiatry, vol. 3, no 5, , p. 427–30 (PMID9774776, DOI10.1038/sj.mp.4000457)
« Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake », Brain Research Reviews, vol. 62, no 2, , p. 147–64 (PMID19931559, DOI10.1016/j.brainresrev.2009.10.007, S2CID37635456)
« Targeted D4 dopamine receptors: implications for drug discovery and therapeutic development », Current Drug Targets, vol. 14, no 4, , p. 507–12 (PMID23469923, DOI10.2174/1389450111314040012)
« Distribution of a novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients », Biological Psychiatry, vol. 34, no 7, , p. 459–64 (PMID8268330, DOI10.1016/0006-3223(93)90236-7, S2CID34841647)
« Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data », Biological Psychiatry, vol. 63, no 2, , p. 197–206 (PMID17574217, DOI10.1016/j.biopsych.2007.04.006, S2CID28997438)
« Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes », European Journal of Pharmacology, vol. 562, no 3, , p. 165–73 (PMID17350612, DOI10.1016/j.ejphar.2007.01.055)
« Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder », The American Journal of Psychiatry, vol. 158, no 7, , p. 1052–7 (PMID11431226, DOI10.1176/appi.ajp.158.7.1052)
« Abnormal early stages of task stimulus processing in children with attention-deficit hyperactivity disorder--evidence from event-related gamma oscillations », Clinical Neurophysiology, vol. 112, no 6, , p. 1096–108 (PMID11377270, DOI10.1016/s1388-2457(01)00524-7, S2CID19789570)
« DRD4 and DAT1 polymorphisms modulate human gamma band responses », Cerebral Cortex, vol. 17, no 5, , p. 1007–19 (PMID16751296, DOI10.1093/cercor/bhl011)
« The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus », American Journal of Human Genetics, vol. 74, no 5, , p. 931–44 (PMID15077199, PMCID1181986, DOI10.1086/420854)
« Population Migration and the Variation of Dopamine D4 Receptor (DRD4) Allele Frequencies Around the Globe », Evolution and Human Behavior, vol. 20, no 5, , p. 309–24 (DOI10.1016/S1090-5138(99)00015-X, S2CID12754148, lire en ligne)
« Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya », BMC Evolutionary Biology, vol. 8, , p. 173 (PMID18544160, PMCID2440754, DOI10.1186/1471-2148-8-173)
« Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking », Nature Genetics, vol. 12, no 1, , p. 78–80 (PMID8528256, DOI10.1038/ng0196-78, S2CID27276401)
« Drd4 gene polymorphisms are associated with personality variation in a passerine bird », Proceedings: Biological Sciences, vol. 274, no 1619, , p. 1685–91 (PMID17472912, PMCID1914334, DOI10.1098/rspb.2007.0337)
« Polymorphisms of the Dopamine D4 Receptor Gene in Stabled Horses are Related to Differences in Behavioral Response to Frustration », Animals, vol. 3, no 3, , p. 663–9 (PMID26479526, PMCID4494454, DOI10.3390/ani3030663)
« Association of polymorphisms in the dopamine D4 receptor gene and the activity-impulsivity endophenotype in dogs », Animal Genetics, vol. 38, no 6, , p. 629–33 (PMID17986156, DOI10.1111/j.1365-2052.2007.01657.x)
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« Facilitatory effect of the dopamine D4 receptor agonist PD168,077 on memory consolidation of an inhibitory avoidance learned response in C57BL/6J mice », Behavioural Brain Research, vol. 142, nos 1–2, , p. 41–52 (PMID12798264, DOI10.1016/s0166-4328(02)00371-6, S2CID21960608)
« A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats », Pharmacology Biochemistry and Behavior, vol. 82, no 1, , p. 148–55 (PMID16154186, DOI10.1016/j.pbb.2005.08.002, S2CID31796938)
« Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat », Behavioural Pharmacology, vol. 19, no 8, , p. 765–76 (PMID19020411, DOI10.1097/FBP.0b013e32831c3b06, S2CID36272297)
« Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys », Psychopharmacology, vol. 142, no 1, , p. 78–84 (PMID10102786, DOI10.1007/s002130050865, S2CID24469748)
« The selective dopamine D4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys », Neuropsychopharmacology, vol. 23, no 4, , p. 405–10 (PMID10989267, DOI10.1016/S0893-133X(00)00133-0)
« Enhancement of gamma activity after selective activation of dopamine D4 receptors in freely moving rats and in a neurodevelopmental model of schizophrenia », Brain Structure & Function, vol. 219, no 6, , p. 2173–80 (PMID23839116, PMCID3859720, DOI10.1007/s00429-013-0607-6)
« Behavioral and neurophysiological effects of Ro 10-5824, a dopamine D4 receptor partial agonist, in common marmosets », Psychopharmacology, vol. 232, no 17, , p. 3287–95 (PMID26041337, DOI10.1007/s00213-015-3978-y, S2CID17141380)
« Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 47, no 15, , p. 3853–64 (PMID15239663, DOI10.1021/jm030505a)
« Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 49, no 25, , p. 7450–65 (PMID17149874, DOI10.1021/jm060662k)
« Cyanoindole derivatives as highly selective dopamine D(4) receptor partial agonists: solid-phase synthesis, binding assays, and functional experiments », Journal of Medicinal Chemistry, vol. 43, no 23, , p. 4563–9 (PMID11087581, DOI10.1021/jm0009989)
« 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 49, no 17, , p. 5093–109 (PMID16913699, DOI10.1021/jm060279f)
« 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist », Journal of Medicinal Chemistry, vol. 49, no 13, , p. 3938–47 (PMID16789750, DOI10.1021/jm060166w)
« 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist », Neuropharmacology, vol. 49, no 1, , p. 112–21 (PMID15992586, DOI10.1016/j.neuropharm.2005.02.004, S2CID7529599)
« Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET », Journal of Medicinal Chemistry, vol. 51, no 6, , p. 1800–10 (PMID18307287, DOI10.1021/jm701375u)
« 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor », Journal of Medicinal Chemistry, vol. 39, no 10, , p. 1941–2 (PMID8642550, DOI10.1021/jm9600712)
« Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity », ACS Medicinal Chemistry Letters, vol. 5, no 9, , p. 1060–4 (PMID25221667, PMCID4160761, DOI10.1021/ml500267c)
« Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapine », Journal of Medicinal Chemistry, vol. 44, no 8, , p. 1151–7 (PMID11312915, DOI10.1021/jm001055e)
escholarship.org
« Population Migration and the Variation of Dopamine D4 Receptor (DRD4) Allele Frequencies Around the Globe », Evolution and Human Behavior, vol. 20, no 5, , p. 309–24 (DOI10.1016/S1090-5138(99)00015-X, S2CID12754148, lire en ligne)
« Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders », Medical Science Monitor, vol. 17, no 9, , RA215–20 (PMID21873960, PMCID3560519, DOI10.12659/MSM.881925)
« Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder », Molecular Psychiatry, vol. 1, no 2, , p. 121–4 (PMID9118321)
« Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder », Molecular Psychiatry, vol. 3, no 5, , p. 427–30 (PMID9774776, DOI10.1038/sj.mp.4000457)
« Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake », Brain Research Reviews, vol. 62, no 2, , p. 147–64 (PMID19931559, DOI10.1016/j.brainresrev.2009.10.007, S2CID37635456)
« Targeted D4 dopamine receptors: implications for drug discovery and therapeutic development », Current Drug Targets, vol. 14, no 4, , p. 507–12 (PMID23469923, DOI10.2174/1389450111314040012)
« Distribution of a novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients », Biological Psychiatry, vol. 34, no 7, , p. 459–64 (PMID8268330, DOI10.1016/0006-3223(93)90236-7, S2CID34841647)
« Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data », Biological Psychiatry, vol. 63, no 2, , p. 197–206 (PMID17574217, DOI10.1016/j.biopsych.2007.04.006, S2CID28997438)
« Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes », European Journal of Pharmacology, vol. 562, no 3, , p. 165–73 (PMID17350612, DOI10.1016/j.ejphar.2007.01.055)
« Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder », The American Journal of Psychiatry, vol. 158, no 7, , p. 1052–7 (PMID11431226, DOI10.1176/appi.ajp.158.7.1052)
« Abnormal early stages of task stimulus processing in children with attention-deficit hyperactivity disorder--evidence from event-related gamma oscillations », Clinical Neurophysiology, vol. 112, no 6, , p. 1096–108 (PMID11377270, DOI10.1016/s1388-2457(01)00524-7, S2CID19789570)
« DRD4 and DAT1 polymorphisms modulate human gamma band responses », Cerebral Cortex, vol. 17, no 5, , p. 1007–19 (PMID16751296, DOI10.1093/cercor/bhl011)
« The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus », American Journal of Human Genetics, vol. 74, no 5, , p. 931–44 (PMID15077199, PMCID1181986, DOI10.1086/420854)
« Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya », BMC Evolutionary Biology, vol. 8, , p. 173 (PMID18544160, PMCID2440754, DOI10.1186/1471-2148-8-173)
« Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking », Nature Genetics, vol. 12, no 1, , p. 78–80 (PMID8528256, DOI10.1038/ng0196-78, S2CID27276401)
« Drd4 gene polymorphisms are associated with personality variation in a passerine bird », Proceedings: Biological Sciences, vol. 274, no 1619, , p. 1685–91 (PMID17472912, PMCID1914334, DOI10.1098/rspb.2007.0337)
« Polymorphisms of the Dopamine D4 Receptor Gene in Stabled Horses are Related to Differences in Behavioral Response to Frustration », Animals, vol. 3, no 3, , p. 663–9 (PMID26479526, PMCID4494454, DOI10.3390/ani3030663)
« Association of polymorphisms in the dopamine D4 receptor gene and the activity-impulsivity endophenotype in dogs », Animal Genetics, vol. 38, no 6, , p. 629–33 (PMID17986156, DOI10.1111/j.1365-2052.2007.01657.x)
« Facilitatory effect of the dopamine D4 receptor agonist PD168,077 on memory consolidation of an inhibitory avoidance learned response in C57BL/6J mice », Behavioural Brain Research, vol. 142, nos 1–2, , p. 41–52 (PMID12798264, DOI10.1016/s0166-4328(02)00371-6, S2CID21960608)
« A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats », Pharmacology Biochemistry and Behavior, vol. 82, no 1, , p. 148–55 (PMID16154186, DOI10.1016/j.pbb.2005.08.002, S2CID31796938)
« Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat », Behavioural Pharmacology, vol. 19, no 8, , p. 765–76 (PMID19020411, DOI10.1097/FBP.0b013e32831c3b06, S2CID36272297)
« Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys », Psychopharmacology, vol. 142, no 1, , p. 78–84 (PMID10102786, DOI10.1007/s002130050865, S2CID24469748)
« The selective dopamine D4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys », Neuropsychopharmacology, vol. 23, no 4, , p. 405–10 (PMID10989267, DOI10.1016/S0893-133X(00)00133-0)
« Enhancement of gamma activity after selective activation of dopamine D4 receptors in freely moving rats and in a neurodevelopmental model of schizophrenia », Brain Structure & Function, vol. 219, no 6, , p. 2173–80 (PMID23839116, PMCID3859720, DOI10.1007/s00429-013-0607-6)
« Behavioral and neurophysiological effects of Ro 10-5824, a dopamine D4 receptor partial agonist, in common marmosets », Psychopharmacology, vol. 232, no 17, , p. 3287–95 (PMID26041337, DOI10.1007/s00213-015-3978-y, S2CID17141380)
« Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 47, no 15, , p. 3853–64 (PMID15239663, DOI10.1021/jm030505a)
« Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 49, no 25, , p. 7450–65 (PMID17149874, DOI10.1021/jm060662k)
« Cyanoindole derivatives as highly selective dopamine D(4) receptor partial agonists: solid-phase synthesis, binding assays, and functional experiments », Journal of Medicinal Chemistry, vol. 43, no 23, , p. 4563–9 (PMID11087581, DOI10.1021/jm0009989)
« 1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction », Journal of Medicinal Chemistry, vol. 49, no 17, , p. 5093–109 (PMID16913699, DOI10.1021/jm060279f)
« 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist », Journal of Medicinal Chemistry, vol. 49, no 13, , p. 3938–47 (PMID16789750, DOI10.1021/jm060166w)
« 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist », Neuropharmacology, vol. 49, no 1, , p. 112–21 (PMID15992586, DOI10.1016/j.neuropharm.2005.02.004, S2CID7529599)
« Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET », Journal of Medicinal Chemistry, vol. 51, no 6, , p. 1800–10 (PMID18307287, DOI10.1021/jm701375u)
« 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor », Journal of Medicinal Chemistry, vol. 39, no 10, , p. 1941–2 (PMID8642550, DOI10.1021/jm9600712)
« Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor », The Journal of Pharmacology and Experimental Therapeutics, vol. 283, no 2, , p. 636–47 (PMID9353380, lire en ligne)
« Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor », Molecular Pharmacology, vol. 50, no 6, , p. 1658–64 (PMID8967990, lire en ligne)
« Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity », ACS Medicinal Chemistry Letters, vol. 5, no 9, , p. 1060–4 (PMID25221667, PMCID4160761, DOI10.1021/ml500267c)
« S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride », The Journal of Pharmacology and Experimental Therapeutics, vol. 287, no 1, , p. 167–86 (PMID9765336, lire en ligne)
« Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapine », Journal of Medicinal Chemistry, vol. 44, no 8, , p. 1151–7 (PMID11312915, DOI10.1021/jm001055e)
« Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake », Brain Research Reviews, vol. 62, no 2, , p. 147–64 (PMID19931559, DOI10.1016/j.brainresrev.2009.10.007, S2CID37635456)
« Distribution of a novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients », Biological Psychiatry, vol. 34, no 7, , p. 459–64 (PMID8268330, DOI10.1016/0006-3223(93)90236-7, S2CID34841647)
« Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data », Biological Psychiatry, vol. 63, no 2, , p. 197–206 (PMID17574217, DOI10.1016/j.biopsych.2007.04.006, S2CID28997438)
« Abnormal early stages of task stimulus processing in children with attention-deficit hyperactivity disorder--evidence from event-related gamma oscillations », Clinical Neurophysiology, vol. 112, no 6, , p. 1096–108 (PMID11377270, DOI10.1016/s1388-2457(01)00524-7, S2CID19789570)
« Population Migration and the Variation of Dopamine D4 Receptor (DRD4) Allele Frequencies Around the Globe », Evolution and Human Behavior, vol. 20, no 5, , p. 309–24 (DOI10.1016/S1090-5138(99)00015-X, S2CID12754148, lire en ligne)
« Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking », Nature Genetics, vol. 12, no 1, , p. 78–80 (PMID8528256, DOI10.1038/ng0196-78, S2CID27276401)
« Facilitatory effect of the dopamine D4 receptor agonist PD168,077 on memory consolidation of an inhibitory avoidance learned response in C57BL/6J mice », Behavioural Brain Research, vol. 142, nos 1–2, , p. 41–52 (PMID12798264, DOI10.1016/s0166-4328(02)00371-6, S2CID21960608)
« A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats », Pharmacology Biochemistry and Behavior, vol. 82, no 1, , p. 148–55 (PMID16154186, DOI10.1016/j.pbb.2005.08.002, S2CID31796938)
« Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat », Behavioural Pharmacology, vol. 19, no 8, , p. 765–76 (PMID19020411, DOI10.1097/FBP.0b013e32831c3b06, S2CID36272297)
« Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys », Psychopharmacology, vol. 142, no 1, , p. 78–84 (PMID10102786, DOI10.1007/s002130050865, S2CID24469748)
« Behavioral and neurophysiological effects of Ro 10-5824, a dopamine D4 receptor partial agonist, in common marmosets », Psychopharmacology, vol. 232, no 17, , p. 3287–95 (PMID26041337, DOI10.1007/s00213-015-3978-y, S2CID17141380)