(en) Clotilde Théry, Laurence Zitvogel et Sebastian Amigorena, « Exosomes: composition, biogenesis and function », Nature Reviews Immunology, vol. 2, no 8, , p. 569–579 (ISSN1474-1741, DOI10.1038/nri855, lire en ligne, consulté le )
(en) Killian O’Brien, Koen Breyne, Stefano Ughetto et Louise C. Laurent, « RNA delivery by extracellular vesicles in mammalian cells and its applications », Nature Reviews Molecular Cell Biology, vol. 21, no 10, , p. 585–606 (ISSN1471-0080, PMID32457507, PMCIDPMC7249041, DOI10.1038/s41580-020-0251-y, lire en ligne, consulté le )
(en) Pasquale Sansone, Claudia Savini, Ivana Kurelac et Qing Chang, « Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer », Proceedings of the National Academy of Sciences, vol. 114, no 43, (ISSN0027-8424 et 1091-6490, PMID29073103, PMCIDPMC5664494, DOI10.1073/pnas.1704862114, lire en ligne, consulté le )
(en) Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et Sujuan Yang, « Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer », Nature, (ISSN1476-4687, DOI10.1038/nature22341, lire en ligne, consulté le )
Clotilde Théry, Matias Ostrowski et Ingrid S. Zeelenberg, « Des vésicules sécrétées in vivo permettent d’améliorer la réponse immune anti-tumorale », médecine/sciences, vol. 24, nos 6-7, , p. 581–583 (ISSN0767-0974 et 1958-5381, DOI10.1051/medsci/20082467581, lire en ligne, consulté le )
doi.org
Miranda, A.M., Lasiecka, Z.M., Xu, Y. et al. Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures. Nat Commun 9, 291 (2018). https://doi.org/10.1038/s41467-017-02533-w
(en) Clotilde Théry, Laurence Zitvogel et Sebastian Amigorena, « Exosomes: composition, biogenesis and function », Nature Reviews Immunology, vol. 2, no 8, , p. 569–579 (ISSN1474-1741, DOI10.1038/nri855, lire en ligne, consulté le )
(en) Killian O’Brien, Koen Breyne, Stefano Ughetto et Louise C. Laurent, « RNA delivery by extracellular vesicles in mammalian cells and its applications », Nature Reviews Molecular Cell Biology, vol. 21, no 10, , p. 585–606 (ISSN1471-0080, PMID32457507, PMCIDPMC7249041, DOI10.1038/s41580-020-0251-y, lire en ligne, consulté le )
(en) Pasquale Sansone, Claudia Savini, Ivana Kurelac et Qing Chang, « Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer », Proceedings of the National Academy of Sciences, vol. 114, no 43, (ISSN0027-8424 et 1091-6490, PMID29073103, PMCIDPMC5664494, DOI10.1073/pnas.1704862114, lire en ligne, consulté le )
(en) Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et Sujuan Yang, « Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer », Nature, (ISSN1476-4687, DOI10.1038/nature22341, lire en ligne, consulté le )
Clotilde Théry, Matias Ostrowski et Ingrid S. Zeelenberg, « Des vésicules sécrétées in vivo permettent d’améliorer la réponse immune anti-tumorale », médecine/sciences, vol. 24, nos 6-7, , p. 581–583 (ISSN0767-0974 et 1958-5381, DOI10.1051/medsci/20082467581, lire en ligne, consulté le )
Vingtdeux, V. et al. Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies. J. Biol. Chem. 282, 18197–18205 (2007) lire en ligne« We showed recently that the amyloid intracellular domain (AICD), which is released by γ-secretase cleavage of APP C-terminal fragments (CTFs), is strongly increased in cells treated with alkalizing drugs[…]We demonstrate that APP, APP-CTFs, and AICD are integrated and secreted within exosomes in differentiated neuroblastoma and primary neuronal culture cells. Together with recent data
showing that amyloid- is also found in exosomes, our data show that multivesicular bodies are essential organelles for APP metabolism and that all APP metabolites can be secreted in the extracellular space ».
medecinesciences.org
Clotilde Théry, Matias Ostrowski et Ingrid S. Zeelenberg, « Des vésicules sécrétées in vivo permettent d’améliorer la réponse immune anti-tumorale », médecine/sciences, vol. 24, nos 6-7, , p. 581–583 (ISSN0767-0974 et 1958-5381, DOI10.1051/medsci/20082467581, lire en ligne, consulté le )
nature.com
(en) Clotilde Théry, Laurence Zitvogel et Sebastian Amigorena, « Exosomes: composition, biogenesis and function », Nature Reviews Immunology, vol. 2, no 8, , p. 569–579 (ISSN1474-1741, DOI10.1038/nri855, lire en ligne, consulté le )
(en) Killian O’Brien, Koen Breyne, Stefano Ughetto et Louise C. Laurent, « RNA delivery by extracellular vesicles in mammalian cells and its applications », Nature Reviews Molecular Cell Biology, vol. 21, no 10, , p. 585–606 (ISSN1471-0080, PMID32457507, PMCIDPMC7249041, DOI10.1038/s41580-020-0251-y, lire en ligne, consulté le )
(en) Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et Sujuan Yang, « Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer », Nature, (ISSN1476-4687, DOI10.1038/nature22341, lire en ligne, consulté le )
(en) Killian O’Brien, Koen Breyne, Stefano Ughetto et Louise C. Laurent, « RNA delivery by extracellular vesicles in mammalian cells and its applications », Nature Reviews Molecular Cell Biology, vol. 21, no 10, , p. 585–606 (ISSN1471-0080, PMID32457507, PMCIDPMC7249041, DOI10.1038/s41580-020-0251-y, lire en ligne, consulté le )
(en) Pasquale Sansone, Claudia Savini, Ivana Kurelac et Qing Chang, « Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer », Proceedings of the National Academy of Sciences, vol. 114, no 43, (ISSN0027-8424 et 1091-6490, PMID29073103, PMCIDPMC5664494, DOI10.1073/pnas.1704862114, lire en ligne, consulté le )
(en) Pasquale Sansone, Claudia Savini, Ivana Kurelac et Qing Chang, « Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer », Proceedings of the National Academy of Sciences, vol. 114, no 43, (ISSN0027-8424 et 1091-6490, PMID29073103, PMCIDPMC5664494, DOI10.1073/pnas.1704862114, lire en ligne, consulté le )
(en) Emily Mullin, « Scientists are genetically engineering the body’s natural nanoparticles to fight pancreatic cancer », MIT Technology Review, (lire en ligne, consulté le )