(en) Leah J. Wilson, Adam Linley, Dean E. Hammond et Fiona E. Hood, « New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome », Cancer Research, vol. 78, no 1, , p. 15–29 (ISSN0008-5472 et 1538-7445, DOI10.1158/0008-5472.CAN-17-2291, lire en ligne, consulté le )
(en) Alexander Drilon, Salvatore Siena, Sai-Hong Ignatius Ou et Manish Patel, « Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1) », Cancer Discovery, vol. 7, no 4, , p. 400–409 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-16-1237, lire en ligne, consulté le )
(en) Alexander Drilon, Sai-Hong Ignatius Ou, Byoung Chul Cho et Dong-Wan Kim, « Repotrectinib (TPX-0005) Is a Next-Generation ROS1/TRK/ALK Inhibitor That Potently Inhibits ROS1/TRK/ALK Solvent- Front Mutations », Cancer Discovery, vol. 8, no 10, , p. 1227–1236 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-18-0484, lire en ligne, consulté le )
acs.org
pubs.acs.org
(en) J. Jean Cui, Michelle Tran-Dubé, Hong Shen et Mitchell Nambu, « Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK) », Journal of Medicinal Chemistry, vol. 54, no 18, , p. 6342–6363 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm2007613, lire en ligne, consulté le )
(en) Thomas H. Marsilje, Wei Pei, Bei Chen et Wenshuo Lu, « Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro- N 2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)- N 4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials », Journal of Medicinal Chemistry, vol. 56, no 14, , p. 5675–5690 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm400402q, lire en ligne, consulté le )
ascopubs.org
(en) Daniel B. Costa, Alice T. Shaw, Sai-Hong I. Ou et Benjamin J. Solomon, « Clinical Experience With Crizotinib in Patients With Advanced ALK -Rearranged Non–Small-Cell Lung Cancer and Brain Metastases », Journal of Clinical Oncology, vol. 33, no 17, , p. 1881–1888 (ISSN0732-183X et 1527-7755, PMID25624436, PMCIDPMC4451171, DOI10.1200/JCO.2014.59.0539, lire en ligne, consulté le )
Philippe L Bedard, David M Hyman, Matthew S Davids et Lillian L Siu, « Small molecules, big impact: 20 years of targeted therapy in oncology », The Lancet, vol. 395, no 10229, , p. 1078–1088 (ISSN0140-6736, DOI10.1016/s0140-6736(20)30164-1, lire en ligne, consulté le )
Yeuan Ting Lee, Yi Jer Tan et Chern Ein Oon, « Molecular targeted therapy: Treating cancer with specificity », European Journal of Pharmacology, vol. 834, , p. 188–196 (ISSN0014-2999, DOI10.1016/j.ejphar.2018.07.034, lire en ligne, consulté le )
Yeuan Ting Lee, Yi Jer Tan et Chern Ein Oon, « Molecular targeted therapy: Treating cancer with specificity », European Journal of Pharmacology, vol. 834, , p. 188–196 (ISSN0014-2999, DOI10.1016/j.ejphar.2018.07.034, lire en ligne, consulté le )
Peter Valent, Bernd Groner, Udo Schumacher et Giulio Superti-Furga, « Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine », Journal of Innate Immunity, vol. 8, no 2, , p. 111–120 (ISSN1662-811X, PMID26845587, PMCIDPMC6738855, DOI10.1159/000443526, lire en ligne, consulté le )
(en) Leah J. Wilson, Adam Linley, Dean E. Hammond et Fiona E. Hood, « New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome », Cancer Research, vol. 78, no 1, , p. 15–29 (ISSN0008-5472 et 1538-7445, DOI10.1158/0008-5472.CAN-17-2291, lire en ligne, consulté le )
Robert Roskoski, « Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes », Pharmacological Research, vol. 103, , p. 26–48 (ISSN1043-6618, DOI10.1016/j.phrs.2015.10.021, lire en ligne, consulté le )
(en) Toshinori Iwahara, Jiro Fujimoto, Duanzhi Wen et Rod Cupples, « Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system », Oncogene, vol. 14, no 4, , p. 439–449 (ISSN1476-5594, DOI10.1038/sj.onc.1200849, lire en ligne, consulté le )
D.T. McManus, M.A. Catherwood, P.D. Carey et R.J.G. Cuthbert, « ALK-positive diffuse large B-cell lymphoma of the stomach associated with a clathrin-ALK rearrangement », Human Pathology, vol. 35, no 10, , p. 1285–1288 (ISSN0046-8177, DOI10.1016/j.humpath.2004.06.001, lire en ligne, consulté le )
(en) Melissa H. Cessna, Holly Zhou, Warren G. Sanger et Sherrie L. Perkins, « Expression of ALK1 and p80 in Inflammatory Myofibroblastic Tumor and Its Mesenchymal Mimics: A Study of 135 Cases », Modern Pathology, vol. 15, no 9, , p. 931–938 (ISSN1530-0285, DOI10.1097/01.MP.0000026615.04130.1F, lire en ligne, consulté le )
(en) Manabu Soda, Young Lim Choi, Munehiro Enomoto et Shuji Takada, « Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer », Nature, vol. 448, no 7153, , p. 561–566 (ISSN1476-4687, DOI10.1038/nature05945, lire en ligne, consulté le )
(en) J. Jean Cui, Michelle Tran-Dubé, Hong Shen et Mitchell Nambu, « Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK) », Journal of Medicinal Chemistry, vol. 54, no 18, , p. 6342–6363 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm2007613, lire en ligne, consulté le )
(en) Alice T. Shaw, Dong-Wan Kim, Kazuhiko Nakagawa et Takashi Seto, « Crizotinib versus Chemotherapy in Advanced ALK -Positive Lung Cancer », New England Journal of Medicine, vol. 368, no 25, , p. 2385–2394 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa1214886, lire en ligne, consulté le )
(en) Benjamin J. Solomon, Tony Mok, Dong-Wan Kim et Yi-Long Wu, « First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer », New England Journal of Medicine, vol. 371, no 23, , p. 2167–2177 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa1408440, lire en ligne, consulté le )
(en) Daniel B. Costa, Alice T. Shaw, Sai-Hong I. Ou et Benjamin J. Solomon, « Clinical Experience With Crizotinib in Patients With Advanced ALK -Rearranged Non–Small-Cell Lung Cancer and Brain Metastases », Journal of Clinical Oncology, vol. 33, no 17, , p. 1881–1888 (ISSN0732-183X et 1527-7755, PMID25624436, PMCIDPMC4451171, DOI10.1200/JCO.2014.59.0539, lire en ligne, consulté le )
(en) Thomas H. Marsilje, Wei Pei, Bei Chen et Wenshuo Lu, « Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro- N 2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)- N 4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials », Journal of Medicinal Chemistry, vol. 56, no 14, , p. 5675–5690 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm400402q, lire en ligne, consulté le )
(en) Alexander Drilon, Salvatore Siena, Sai-Hong Ignatius Ou et Manish Patel, « Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1) », Cancer Discovery, vol. 7, no 4, , p. 400–409 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-16-1237, lire en ligne, consulté le )
J. Sachdev, H.T. Arkenau, J.R. Infante et M.M. Mita, « 506 Phase (Ph) 1/2a study of TSR-011, a potent inhibitor of ALK and TRK, in advanced solid tumors including crizotinib-resistant ALK positive non-small cell lung cancer », European Journal of Cancer, vol. 50, , p. 165 (ISSN0959-8049, DOI10.1016/s0959-8049(14)70632-x, lire en ligne, consulté le )
(en) Alexander Drilon, Sai-Hong Ignatius Ou, Byoung Chul Cho et Dong-Wan Kim, « Repotrectinib (TPX-0005) Is a Next-Generation ROS1/TRK/ALK Inhibitor That Potently Inhibits ROS1/TRK/ALK Solvent- Front Mutations », Cancer Discovery, vol. 8, no 10, , p. 1227–1236 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-18-0484, lire en ligne, consulté le )
(en) David W. Threadgill, Andrzej A. Dlugosz, Laura A. Hansen et Tamar Tennenbaum, « Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype », Science, vol. 269, no 5221, , p. 230–234 (ISSN0036-8075 et 1095-9203, DOI10.1126/science.7618084, lire en ligne, consulté le )
(en) Carl P. Blobel, « ADAMs: key components in EGFR signalling and development », Nature Reviews Molecular Cell Biology, vol. 6, no 1, , p. 32–43 (ISSN1471-0080, DOI10.1038/nrm1548, lire en ligne, consulté le )
David S. Salomon, Ralf Brandt, Fortunato Ciardiello et Nicola Normanno, « Epidermal growth factor-related peptides and their receptors in human malignancies », Critical Reviews in Oncology/Hematology, vol. 19, no 3, , p. 183–232 (ISSN1040-8428, DOI10.1016/1040-8428(94)00144-I, lire en ligne, consulté le )
Giulio Metro, Giovanna Finocchiaro, Luca Toschi et Stefania Bartolini, « Epidermal Growth Factor Receptor (EGFR) Targeted Therapies in Non- Small Cell Lung Cancer (NSCLC) », Reviews on Recent Clinical Trials, vol. 1, no 1, , p. 1–13 (ISSN1574-8871, DOI10.2174/157488706775246157, lire en ligne, consulté le )
(en) Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et Sarada Gurubhagavatula, « Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib », New England Journal of Medicine, vol. 350, no 21, , p. 2129–2139 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa040938, lire en ligne, consulté le )
(en) Paolo Maione, Paola Claudia Sacco, Assunta Sgambato et Francesca Casaluce, « Overcoming resistance to targeted therapies in NSCLC: current approaches and clinical application », Therapeutic Advances in Medical Oncology, vol. 7, no 5, , p. 263–273 (ISSN1758-8359 et 1758-8359, PMID26327924, PMCIDPMC4543855, DOI10.1177/1758834015595048, lire en ligne, consulté le )
(en) Joshua Z. Drago, Shanu Modi et Sarat Chandarlapaty, « Unlocking the potential of antibody–drug conjugates for cancer therapy », Nature Reviews Clinical Oncology, vol. 18, no 6, , p. 327–344 (ISSN1759-4782, DOI10.1038/s41571-021-00470-8, lire en ligne, consulté le )
(en) Kyoji Tsuchikama et Zhiqiang An, « Antibody-drug conjugates: recent advances in conjugation and linker chemistries », Protein & Cell, vol. 9, no 1, , p. 33–46 (ISSN1674-8018, DOI10.1007/s13238-016-0323-0, lire en ligne, consulté le )
Philippe L Bedard, David M Hyman, Matthew S Davids et Lillian L Siu, « Small molecules, big impact: 20 years of targeted therapy in oncology », The Lancet, vol. 395, no 10229, , p. 1078–1088 (ISSN0140-6736, DOI10.1016/s0140-6736(20)30164-1, lire en ligne, consulté le )
Yeuan Ting Lee, Yi Jer Tan et Chern Ein Oon, « Molecular targeted therapy: Treating cancer with specificity », European Journal of Pharmacology, vol. 834, , p. 188–196 (ISSN0014-2999, DOI10.1016/j.ejphar.2018.07.034, lire en ligne, consulté le )
Peter Valent, Bernd Groner, Udo Schumacher et Giulio Superti-Furga, « Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine », Journal of Innate Immunity, vol. 8, no 2, , p. 111–120 (ISSN1662-811X, PMID26845587, PMCIDPMC6738855, DOI10.1159/000443526, lire en ligne, consulté le )
Robert Roskoski, « Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes », Pharmacological Research, vol. 103, , p. 26–48 (ISSN1043-6618, DOI10.1016/j.phrs.2015.10.021, lire en ligne, consulté le )
D.T. McManus, M.A. Catherwood, P.D. Carey et R.J.G. Cuthbert, « ALK-positive diffuse large B-cell lymphoma of the stomach associated with a clathrin-ALK rearrangement », Human Pathology, vol. 35, no 10, , p. 1285–1288 (ISSN0046-8177, DOI10.1016/j.humpath.2004.06.001, lire en ligne, consulté le )
J. Sachdev, H.T. Arkenau, J.R. Infante et M.M. Mita, « 506 Phase (Ph) 1/2a study of TSR-011, a potent inhibitor of ALK and TRK, in advanced solid tumors including crizotinib-resistant ALK positive non-small cell lung cancer », European Journal of Cancer, vol. 50, , p. 165 (ISSN0959-8049, DOI10.1016/s0959-8049(14)70632-x, lire en ligne, consulté le )
(en) Kyoji Tsuchikama et Zhiqiang An, « Antibody-drug conjugates: recent advances in conjugation and linker chemistries », Protein & Cell, vol. 9, no 1, , p. 33–46 (ISSN1674-8018, DOI10.1007/s13238-016-0323-0, lire en ligne, consulté le )
inserm.fr
Inserm, « Thérapie ciblée », sur www.inserm.fr (consulté le )
issn.org
portal.issn.org
Philippe L Bedard, David M Hyman, Matthew S Davids et Lillian L Siu, « Small molecules, big impact: 20 years of targeted therapy in oncology », The Lancet, vol. 395, no 10229, , p. 1078–1088 (ISSN0140-6736, DOI10.1016/s0140-6736(20)30164-1, lire en ligne, consulté le )
Yeuan Ting Lee, Yi Jer Tan et Chern Ein Oon, « Molecular targeted therapy: Treating cancer with specificity », European Journal of Pharmacology, vol. 834, , p. 188–196 (ISSN0014-2999, DOI10.1016/j.ejphar.2018.07.034, lire en ligne, consulté le )
Yeuan Ting Lee, Yi Jer Tan et Chern Ein Oon, « Molecular targeted therapy: Treating cancer with specificity », European Journal of Pharmacology, vol. 834, , p. 188–196 (ISSN0014-2999, DOI10.1016/j.ejphar.2018.07.034, lire en ligne, consulté le )
Peter Valent, Bernd Groner, Udo Schumacher et Giulio Superti-Furga, « Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine », Journal of Innate Immunity, vol. 8, no 2, , p. 111–120 (ISSN1662-811X, PMID26845587, PMCIDPMC6738855, DOI10.1159/000443526, lire en ligne, consulté le )
(en) Leah J. Wilson, Adam Linley, Dean E. Hammond et Fiona E. Hood, « New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome », Cancer Research, vol. 78, no 1, , p. 15–29 (ISSN0008-5472 et 1538-7445, DOI10.1158/0008-5472.CAN-17-2291, lire en ligne, consulté le )
Robert Roskoski, « Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes », Pharmacological Research, vol. 103, , p. 26–48 (ISSN1043-6618, DOI10.1016/j.phrs.2015.10.021, lire en ligne, consulté le )
(en) Toshinori Iwahara, Jiro Fujimoto, Duanzhi Wen et Rod Cupples, « Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system », Oncogene, vol. 14, no 4, , p. 439–449 (ISSN1476-5594, DOI10.1038/sj.onc.1200849, lire en ligne, consulté le )
D.T. McManus, M.A. Catherwood, P.D. Carey et R.J.G. Cuthbert, « ALK-positive diffuse large B-cell lymphoma of the stomach associated with a clathrin-ALK rearrangement », Human Pathology, vol. 35, no 10, , p. 1285–1288 (ISSN0046-8177, DOI10.1016/j.humpath.2004.06.001, lire en ligne, consulté le )
(en) Melissa H. Cessna, Holly Zhou, Warren G. Sanger et Sherrie L. Perkins, « Expression of ALK1 and p80 in Inflammatory Myofibroblastic Tumor and Its Mesenchymal Mimics: A Study of 135 Cases », Modern Pathology, vol. 15, no 9, , p. 931–938 (ISSN1530-0285, DOI10.1097/01.MP.0000026615.04130.1F, lire en ligne, consulté le )
(en) Manabu Soda, Young Lim Choi, Munehiro Enomoto et Shuji Takada, « Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer », Nature, vol. 448, no 7153, , p. 561–566 (ISSN1476-4687, DOI10.1038/nature05945, lire en ligne, consulté le )
(en) J. Jean Cui, Michelle Tran-Dubé, Hong Shen et Mitchell Nambu, « Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK) », Journal of Medicinal Chemistry, vol. 54, no 18, , p. 6342–6363 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm2007613, lire en ligne, consulté le )
(en) Alice T. Shaw, Dong-Wan Kim, Kazuhiko Nakagawa et Takashi Seto, « Crizotinib versus Chemotherapy in Advanced ALK -Positive Lung Cancer », New England Journal of Medicine, vol. 368, no 25, , p. 2385–2394 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa1214886, lire en ligne, consulté le )
(en) Benjamin J. Solomon, Tony Mok, Dong-Wan Kim et Yi-Long Wu, « First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer », New England Journal of Medicine, vol. 371, no 23, , p. 2167–2177 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa1408440, lire en ligne, consulté le )
(en) Daniel B. Costa, Alice T. Shaw, Sai-Hong I. Ou et Benjamin J. Solomon, « Clinical Experience With Crizotinib in Patients With Advanced ALK -Rearranged Non–Small-Cell Lung Cancer and Brain Metastases », Journal of Clinical Oncology, vol. 33, no 17, , p. 1881–1888 (ISSN0732-183X et 1527-7755, PMID25624436, PMCIDPMC4451171, DOI10.1200/JCO.2014.59.0539, lire en ligne, consulté le )
(en) Thomas H. Marsilje, Wei Pei, Bei Chen et Wenshuo Lu, « Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro- N 2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)- N 4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials », Journal of Medicinal Chemistry, vol. 56, no 14, , p. 5675–5690 (ISSN0022-2623 et 1520-4804, DOI10.1021/jm400402q, lire en ligne, consulté le )
(en) Alexander Drilon, Salvatore Siena, Sai-Hong Ignatius Ou et Manish Patel, « Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1) », Cancer Discovery, vol. 7, no 4, , p. 400–409 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-16-1237, lire en ligne, consulté le )
J. Sachdev, H.T. Arkenau, J.R. Infante et M.M. Mita, « 506 Phase (Ph) 1/2a study of TSR-011, a potent inhibitor of ALK and TRK, in advanced solid tumors including crizotinib-resistant ALK positive non-small cell lung cancer », European Journal of Cancer, vol. 50, , p. 165 (ISSN0959-8049, DOI10.1016/s0959-8049(14)70632-x, lire en ligne, consulté le )
(en) Alexander Drilon, Sai-Hong Ignatius Ou, Byoung Chul Cho et Dong-Wan Kim, « Repotrectinib (TPX-0005) Is a Next-Generation ROS1/TRK/ALK Inhibitor That Potently Inhibits ROS1/TRK/ALK Solvent- Front Mutations », Cancer Discovery, vol. 8, no 10, , p. 1227–1236 (ISSN2159-8274 et 2159-8290, DOI10.1158/2159-8290.CD-18-0484, lire en ligne, consulté le )
(en) David W. Threadgill, Andrzej A. Dlugosz, Laura A. Hansen et Tamar Tennenbaum, « Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype », Science, vol. 269, no 5221, , p. 230–234 (ISSN0036-8075 et 1095-9203, DOI10.1126/science.7618084, lire en ligne, consulté le )
(en) Carl P. Blobel, « ADAMs: key components in EGFR signalling and development », Nature Reviews Molecular Cell Biology, vol. 6, no 1, , p. 32–43 (ISSN1471-0080, DOI10.1038/nrm1548, lire en ligne, consulté le )
David S. Salomon, Ralf Brandt, Fortunato Ciardiello et Nicola Normanno, « Epidermal growth factor-related peptides and their receptors in human malignancies », Critical Reviews in Oncology/Hematology, vol. 19, no 3, , p. 183–232 (ISSN1040-8428, DOI10.1016/1040-8428(94)00144-I, lire en ligne, consulté le )
Giulio Metro, Giovanna Finocchiaro, Luca Toschi et Stefania Bartolini, « Epidermal Growth Factor Receptor (EGFR) Targeted Therapies in Non- Small Cell Lung Cancer (NSCLC) », Reviews on Recent Clinical Trials, vol. 1, no 1, , p. 1–13 (ISSN1574-8871, DOI10.2174/157488706775246157, lire en ligne, consulté le )
(en) Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et Sarada Gurubhagavatula, « Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib », New England Journal of Medicine, vol. 350, no 21, , p. 2129–2139 (ISSN0028-4793 et 1533-4406, DOI10.1056/NEJMoa040938, lire en ligne, consulté le )
(en) Paolo Maione, Paola Claudia Sacco, Assunta Sgambato et Francesca Casaluce, « Overcoming resistance to targeted therapies in NSCLC: current approaches and clinical application », Therapeutic Advances in Medical Oncology, vol. 7, no 5, , p. 263–273 (ISSN1758-8359 et 1758-8359, PMID26327924, PMCIDPMC4543855, DOI10.1177/1758834015595048, lire en ligne, consulté le )
(en) Joshua Z. Drago, Shanu Modi et Sarat Chandarlapaty, « Unlocking the potential of antibody–drug conjugates for cancer therapy », Nature Reviews Clinical Oncology, vol. 18, no 6, , p. 327–344 (ISSN1759-4782, DOI10.1038/s41571-021-00470-8, lire en ligne, consulté le )
(en) Kyoji Tsuchikama et Zhiqiang An, « Antibody-drug conjugates: recent advances in conjugation and linker chemistries », Protein & Cell, vol. 9, no 1, , p. 33–46 (ISSN1674-8018, DOI10.1007/s13238-016-0323-0, lire en ligne, consulté le )
(en) C. Cunningham et J. Nemunaitis, « A phase I trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9, 2001 », Human Gene Therapy, vol. 12, no 12, , p. 1594–1596 (ISSN1043-0342, PMID11529249, résumé).
(en) Toshinori Iwahara, Jiro Fujimoto, Duanzhi Wen et Rod Cupples, « Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system », Oncogene, vol. 14, no 4, , p. 439–449 (ISSN1476-5594, DOI10.1038/sj.onc.1200849, lire en ligne, consulté le )
(en) Melissa H. Cessna, Holly Zhou, Warren G. Sanger et Sherrie L. Perkins, « Expression of ALK1 and p80 in Inflammatory Myofibroblastic Tumor and Its Mesenchymal Mimics: A Study of 135 Cases », Modern Pathology, vol. 15, no 9, , p. 931–938 (ISSN1530-0285, DOI10.1097/01.MP.0000026615.04130.1F, lire en ligne, consulté le )
(en) Manabu Soda, Young Lim Choi, Munehiro Enomoto et Shuji Takada, « Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer », Nature, vol. 448, no 7153, , p. 561–566 (ISSN1476-4687, DOI10.1038/nature05945, lire en ligne, consulté le )
(en) Carl P. Blobel, « ADAMs: key components in EGFR signalling and development », Nature Reviews Molecular Cell Biology, vol. 6, no 1, , p. 32–43 (ISSN1471-0080, DOI10.1038/nrm1548, lire en ligne, consulté le )
(en) Joshua Z. Drago, Shanu Modi et Sarat Chandarlapaty, « Unlocking the potential of antibody–drug conjugates for cancer therapy », Nature Reviews Clinical Oncology, vol. 18, no 6, , p. 327–344 (ISSN1759-4782, DOI10.1038/s41571-021-00470-8, lire en ligne, consulté le )
nejm.org
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