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Cheng Y, Prusoff WH (decembro de 1973). "Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction". Biochemical Pharmacology22 (23): 3099–108. PMID4202581. doi:10.1016/0006-2952(73)90196-2.
Hoetelmans RM. "IC50 versus EC50". PK-PD relationships for anti-retroviral drugs. Amsterdam: Slotervaart Hospital. Arquivado dende o orixinal o 2017-05-28 – vía U.S. Food and Drug Administration.