Nicolaes GA, Dahlbäck B (February 2003). "Congenital and acquired activated protein C resistance". Seminars in Vascular Medicine3 (1): 33–46. PMID15199491. doi:10.1055/s-2003-38331.
Eichacker PQ, Natanson C, Danner RL (October 2006). "Surviving sepsis--practice guidelines, marketing campaigns, and Eli Lilly". The New England Journal of Medicine355 (16): 1640–2. PMID17050887. doi:10.1056/NEJMp068197.
Martí-Carvajal AJ, Solà I, Gluud C, Lathyris D, Cardona AF (2012-12-12). "Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients". The Cochrane Database of Systematic Reviews12: CD004388. ISSN1469-493X. PMID23235609. doi:10.1002/14651858.CD004388.pub6.
Kylat, Ranjit; Ohlsson, Arne (April 18, 2012). "Recombinant human activated protein C for severe sepsis in neonates.". Cochrane Database of Systematic Reviews (4): CD005385. doi:10.1002/14651858.CD005385.pub3.
Kisiel W, Ericsson LH, Davie EW (November 1976). "Proteolytic activation of protein C from bovine plasma". Biochemistry15 (22): 4893–900. PMID990250. doi:10.1021/bi00667a022.
Mosnier LO, Griffin JH (2006). "Protein C anticoagulant activity in relation to anti-inflammatory and anti-apoptotic activities". Frontiers in Bioscience11: 2381–99. PMID16720321. doi:10.2741/1977.
Kisiel W, Canfield WM, Ericsson LH, Davie EW (December 1977). "Anticoagulant properties of bovine plasma protein C following activation by thrombin". Biochemistry16 (26): 5824–31. PMID588557. doi:10.1021/bi00645a029.
Vehar GA, Davie EW (February 1980). "Preparation and properties of bovine factor VIII (antihemophilic factor)". Biochemistry19 (3): 401–10. PMID7356933. doi:10.1021/bi00544a001.
Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH (May 1994). "Mutation in blood coagulation factor V associated with resistance to activated protein C". Nature369 (6475): 64–7. PMID8164741. doi:10.1038/369064a0.
PROWESS: recombinant Human Activated PROtein C Worldwide Evaluation in Severe Sepsis; Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ (March 2001). "Efficacy and safety of recombinant human activated protein C for severe sepsis". The New England Journal of Medicine344 (10): 699–709. PMID11236773. doi:10.1056/NEJM200103083441001.
Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W (June 2002). "Activation of endothelial cell protease activated receptor 1 by the protein C pathway". Science296 (5574): 1880–2. PMID12052963. doi:10.1126/science.1071699.
Wildhagen KC, Lutgens E, Loubele ST, ten Cate H, Nicolaes GA (December 2011). "The structure-function relationship of activated protein C. Lessons from natural and engineered mutations". Thrombosis and Haemostasis106 (6): 1034–45. PMID22072231. doi:10.1160/TH11-08-0522.
Gu JM, Crawley JT, Ferrell G, Zhang F, Li W, Esmon NL, Esmon CT (November 2002). "Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality". The Journal of Biological Chemistry277 (45): 43335–43. PMID12218060. doi:10.1074/jbc.M207538200.
España F, Berrettini M, Griffin JH (August 1989). "Purification and characterization of plasma protein C inhibitor". Thrombosis Research55 (3): 369–84. PMID2551064. doi:10.1016/0049-3848(89)90069-8.
Nicolaes GA, Tans G, Thomassen MC, Hemker HC, Pabinger I, Varadi K, Schwarz HP, Rosing J (September 1995). "Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C". The Journal of Biological Chemistry270 (36): 21158–66. PMID7673148. doi:10.1074/jbc.270.36.21158.
Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G (June 2008). "Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)". Chest133 (6 Suppl): 160S–198S. PMID18574265. doi:10.1378/chest.08-0670.
Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, François B, Guy JS, Brückmann M, Rea-Neto A, Rossaint R, Perrotin D, Sablotzki A, Arkins N, Utterback BG, Macias WL (September 2005). "Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death". The New England Journal of Medicine353 (13): 1332–41. PMID16192478. doi:10.1056/NEJMoa050935.
Martí-Carvajal AJ, Solà I, Lathyris D, Cardona AF (2011-04-13). Martí-Carvajal AJ, ed. "Human recombinant activated protein C for severe sepsis". The Cochrane Database of Systematic Reviews (4): CD004388. PMID21491390. doi:10.1002/14651858.CD004388.pub4.
Griffin JH, Fernández JA, Mosnier LO, Liu D, Cheng T, Guo H, Zlokovic BV (2006). "The promise of protein C". Blood Cells, Molecules & Diseases36 (2): 211–6. PMID16464623. doi:10.1016/j.bcmd.2005.12.023.
nih.gov
ncbi.nlm.nih.gov
Nicolaes GA, Dahlbäck B (February 2003). "Congenital and acquired activated protein C resistance". Seminars in Vascular Medicine3 (1): 33–46. PMID15199491. doi:10.1055/s-2003-38331.
Eichacker PQ, Natanson C, Danner RL (October 2006). "Surviving sepsis--practice guidelines, marketing campaigns, and Eli Lilly". The New England Journal of Medicine355 (16): 1640–2. PMID17050887. doi:10.1056/NEJMp068197.
Martí-Carvajal AJ, Solà I, Gluud C, Lathyris D, Cardona AF (2012-12-12). "Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients". The Cochrane Database of Systematic Reviews12: CD004388. ISSN1469-493X. PMID23235609. doi:10.1002/14651858.CD004388.pub6.
Mammen EF, Thomas WR, Seegers WH (December 1960). "Activation of purified prothrombin to autoprothrombin I or autoprothrombin II (platelet cofactor II or autoprothrombin II-A)". Thrombosis Et Diathesis Haemorrhagica5: 218–49. PMID13765990.
Kisiel W, Ericsson LH, Davie EW (November 1976). "Proteolytic activation of protein C from bovine plasma". Biochemistry15 (22): 4893–900. PMID990250. doi:10.1021/bi00667a022.
Mosnier LO, Griffin JH (2006). "Protein C anticoagulant activity in relation to anti-inflammatory and anti-apoptotic activities". Frontiers in Bioscience11: 2381–99. PMID16720321. doi:10.2741/1977.
Kisiel W, Canfield WM, Ericsson LH, Davie EW (December 1977). "Anticoagulant properties of bovine plasma protein C following activation by thrombin". Biochemistry16 (26): 5824–31. PMID588557. doi:10.1021/bi00645a029.
Vehar GA, Davie EW (February 1980). "Preparation and properties of bovine factor VIII (antihemophilic factor)". Biochemistry19 (3): 401–10. PMID7356933. doi:10.1021/bi00544a001.
Walker FJ (June 1980). "Regulation of activated protein C by a new protein. A possible function for bovine protein S". The Journal of Biological Chemistry255 (12): 5521–4. PMID6892911.
Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH (May 1994). "Mutation in blood coagulation factor V associated with resistance to activated protein C". Nature369 (6475): 64–7. PMID8164741. doi:10.1038/369064a0.
PROWESS: recombinant Human Activated PROtein C Worldwide Evaluation in Severe Sepsis; Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ (March 2001). "Efficacy and safety of recombinant human activated protein C for severe sepsis". The New England Journal of Medicine344 (10): 699–709. PMID11236773. doi:10.1056/NEJM200103083441001.
Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W (June 2002). "Activation of endothelial cell protease activated receptor 1 by the protein C pathway". Science296 (5574): 1880–2. PMID12052963. doi:10.1126/science.1071699.
Wildhagen KC, Lutgens E, Loubele ST, ten Cate H, Nicolaes GA (December 2011). "The structure-function relationship of activated protein C. Lessons from natural and engineered mutations". Thrombosis and Haemostasis106 (6): 1034–45. PMID22072231. doi:10.1160/TH11-08-0522.
Gu JM, Crawley JT, Ferrell G, Zhang F, Li W, Esmon NL, Esmon CT (November 2002). "Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality". The Journal of Biological Chemistry277 (45): 43335–43. PMID12218060. doi:10.1074/jbc.M207538200.
España F, Berrettini M, Griffin JH (August 1989). "Purification and characterization of plasma protein C inhibitor". Thrombosis Research55 (3): 369–84. PMID2551064. doi:10.1016/0049-3848(89)90069-8.
Nicolaes GA, Tans G, Thomassen MC, Hemker HC, Pabinger I, Varadi K, Schwarz HP, Rosing J (September 1995). "Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C". The Journal of Biological Chemistry270 (36): 21158–66. PMID7673148. doi:10.1074/jbc.270.36.21158.
Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G (June 2008). "Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)". Chest133 (6 Suppl): 160S–198S. PMID18574265. doi:10.1378/chest.08-0670.
Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, François B, Guy JS, Brückmann M, Rea-Neto A, Rossaint R, Perrotin D, Sablotzki A, Arkins N, Utterback BG, Macias WL (September 2005). "Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death". The New England Journal of Medicine353 (13): 1332–41. PMID16192478. doi:10.1056/NEJMoa050935.
Martí-Carvajal AJ, Solà I, Lathyris D, Cardona AF (2011-04-13). Martí-Carvajal AJ, ed. "Human recombinant activated protein C for severe sepsis". The Cochrane Database of Systematic Reviews (4): CD004388. PMID21491390. doi:10.1002/14651858.CD004388.pub4.
Martí-Carvajal AJ1, Solà I, Gluud C, Lathyris D, Cardona AF. Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients.Cochrane Database Syst Rev. 2012 Dec 12;12:CD004388. doi: 10.1002/14651858.CD004388.pub6. PMID 23235609update
Griffin JH, Fernández JA, Mosnier LO, Liu D, Cheng T, Guo H, Zlokovic BV (2006). "The promise of protein C". Blood Cells, Molecules & Diseases36 (2): 211–6. PMID16464623. doi:10.1016/j.bcmd.2005.12.023.
worldcat.org
Martí-Carvajal AJ, Solà I, Gluud C, Lathyris D, Cardona AF (2012-12-12). "Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients". The Cochrane Database of Systematic Reviews12: CD004388. ISSN1469-493X. PMID23235609. doi:10.1002/14651858.CD004388.pub6.