Itóh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, ten Dijke P. "Transforming growth factor beta1 induces nuclear export of inhibitory Smad7" 273 (44). PMID9786930. doi:10.1074/jbc.273.44.29195.
Shi Y, Hata A, Lo RS, Massagué J, Pavletich NP. "A structural basis for mutational inactivation of the tumour suppressor Smad4" 388 (6637). PMID9214508. doi:10.1038/40431.
Kretzschmar M, Doody J, Massagué J. "Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1" 389 (6651). PMID9335504. doi:10.1038/39348.
Yakymovych I, Ten Dijke P, Heldin CH, Souchelnytskyi S. "Regulation of Smad signaling by protein kinase C" 15 (3). PMID11259364. doi:10.1096/fj.00-0474fje.
Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW, Richardson MA, Topper JN, Gimbrone MA, Wrana JL, Falb D. "The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling" 89 (7). PMID9215638. doi:10.1016/S0092-8674(00)80303-7.
Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K, ten Dijke P, Sugino H, Nishihara T. "Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells" 274 (19). PMID10224135. doi:10.1074/jbc.274.19.13637.
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. "Identification of Smad7, a TGFbeta-inducible antagonist of TGF-β signalling" 389 (6651). PMID9335507. doi:10.1038/39369.
Lee YS, Kim JH, Kim ST, Kwon JY, Hong S, Kim SJ, Park SH. "Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-beta1-induced negative regulation of IL-1R/TLR signaling" 393 (4). PMID20171181. doi:10.1016/j.bbrc.2010.02.094.
Arnold NB, Ketterer K, Kleeff J, Friess H, Büchler MW, Korc M. "Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer" 64 (10). PMID15150118. doi:10.1158/0008-5472.CAN-03-2999.
Salomon DS, Brandt R, Ciardiello F, Normanno N. "Epidermal growth factor-related peptides and their receptors in human malignancies" 19 (3). PMID7612182. doi:10.1016/1040-8428(94)00144-I.
Burgess AW, Cho HS, Eigenbrot C, Ferguson KM, Garrett TP, Leahy DJ, Lemmon MA, Sliwkowski MX, Ward CW, Yokoyama S. "An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors" 12 (3). PMID14527402. doi:10.1016/S1097-2765(03)00350-2.
Kim S, Choi JH, Lim HI, Lee SK, Kim WW, Cho S, Kim JS, Kim JH, Choe JH, Nam SJ, Lee JE, Yang JH. "EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line" 21 (6). PMID19385051. doi:10.1016/j.cellsig.2009.01.034.
Kim S, Han J, Lee SK, Koo M, Cho DH, Bae SY, Choi MY, Kim JS, Kim JH, Choe JH, Yang JH, Nam SJ, Lee JE. "Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells" 314 (2). PMID22033246. doi:10.1016/j.canlet.2011.09.024.
Grönroos E, Hellman U, Heldin CH, Ericsson J (septiembre de 2002). "Control of Smad7 stability by competition between acetylation and ubiquitination". Mol. Cell10 (3): 483–93. PMID12408818. doi:10.1016/S1097-2765(02)00639-1.
Yanagisawa M, Nakashima K, Takeda K, Ochiai W, Takizawa T, Ueno M, Takizawa M, Shibuya H, Taga T (diciembre de 2001). "Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7". Genes Cells6 (12): 1091–9. PMID11737269. doi:10.1046/j.1365-2443.2001.00483.x.
Imoto S, Sugiyama K, Muromoto R, Sato N, Yamamoto T, Matsuda T (septiembre de 2003). "Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3". J. Biol. Chem.278 (36): 34253–8. PMID12815042. doi:10.1074/jbc.M304961200.
Lebrun JJ, Takabe K, Chen Y, Vale W (enero de 1999). "Roles of pathway-specific and inhibitory Smads in activin receptor signaling". Mol. Endocrinol.13 (1): 15–23. PMID9892009. doi:10.1210/mend.13.1.0218.
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL (diciembre de 2000). "Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation". Mol. Cell6 (6): 1365–75. PMID11163210. doi:10.1016/S1097-2765(00)00134-9.
Lee YS, Han JM, Son SH, Choi JW, Jeon EJ, Bae SC, Park YI, Kim S (julio de 2008). "AIMP1/p43 downregulates TGF-beta signaling via stabilization of smurf2". Biochem. Biophys. Res. Commun.371 (3): 395–400. PMID18448069. doi:10.1016/j.bbrc.2008.04.099.
Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K (julio de 2004). "Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling". J. Biol. Chem.279 (30): 31568–74. PMID15148321. doi:10.1074/jbc.M313977200.
Ferrigno O, Lallemand F, Verrecchia F, L'Hoste S, Camonis J, Atfi A, Mauviel A (julio de 2002). "Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling". Oncogene21 (32): 4879–84. PMID12118366. doi:10.1038/sj.onc.1205623.
Itóh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, ten Dijke P. "Transforming growth factor beta1 induces nuclear export of inhibitory Smad7" 273 (44). PMID9786930. doi:10.1074/jbc.273.44.29195.
Shi Y, Hata A, Lo RS, Massagué J, Pavletich NP. "A structural basis for mutational inactivation of the tumour suppressor Smad4" 388 (6637). PMID9214508. doi:10.1038/40431.
Kretzschmar M, Doody J, Massagué J. "Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1" 389 (6651). PMID9335504. doi:10.1038/39348.
Yakymovych I, Ten Dijke P, Heldin CH, Souchelnytskyi S. "Regulation of Smad signaling by protein kinase C" 15 (3). PMID11259364. doi:10.1096/fj.00-0474fje.
Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW, Richardson MA, Topper JN, Gimbrone MA, Wrana JL, Falb D. "The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling" 89 (7). PMID9215638. doi:10.1016/S0092-8674(00)80303-7.
Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K, ten Dijke P, Sugino H, Nishihara T. "Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells" 274 (19). PMID10224135. doi:10.1074/jbc.274.19.13637.
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. "Identification of Smad7, a TGFbeta-inducible antagonist of TGF-β signalling" 389 (6651). PMID9335507. doi:10.1038/39369.
Lee YS, Kim JH, Kim ST, Kwon JY, Hong S, Kim SJ, Park SH. "Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-beta1-induced negative regulation of IL-1R/TLR signaling" 393 (4). PMID20171181. doi:10.1016/j.bbrc.2010.02.094.
Arnold NB, Ketterer K, Kleeff J, Friess H, Büchler MW, Korc M. "Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer" 64 (10). PMID15150118. doi:10.1158/0008-5472.CAN-03-2999.
Salomon DS, Brandt R, Ciardiello F, Normanno N. "Epidermal growth factor-related peptides and their receptors in human malignancies" 19 (3). PMID7612182. doi:10.1016/1040-8428(94)00144-I.
Burgess AW, Cho HS, Eigenbrot C, Ferguson KM, Garrett TP, Leahy DJ, Lemmon MA, Sliwkowski MX, Ward CW, Yokoyama S. "An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors" 12 (3). PMID14527402. doi:10.1016/S1097-2765(03)00350-2.
Kim S, Choi JH, Lim HI, Lee SK, Kim WW, Cho S, Kim JS, Kim JH, Choe JH, Nam SJ, Lee JE, Yang JH. "EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line" 21 (6). PMID19385051. doi:10.1016/j.cellsig.2009.01.034.
Kim S, Han J, Lee SK, Koo M, Cho DH, Bae SY, Choi MY, Kim JS, Kim JH, Choe JH, Yang JH, Nam SJ, Lee JE. "Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells" 314 (2). PMID22033246. doi:10.1016/j.canlet.2011.09.024.
Grönroos E, Hellman U, Heldin CH, Ericsson J (septiembre de 2002). "Control of Smad7 stability by competition between acetylation and ubiquitination". Mol. Cell10 (3): 483–93. PMID12408818. doi:10.1016/S1097-2765(02)00639-1.
Yanagisawa M, Nakashima K, Takeda K, Ochiai W, Takizawa T, Ueno M, Takizawa M, Shibuya H, Taga T (diciembre de 2001). "Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7". Genes Cells6 (12): 1091–9. PMID11737269. doi:10.1046/j.1365-2443.2001.00483.x.
Imoto S, Sugiyama K, Muromoto R, Sato N, Yamamoto T, Matsuda T (septiembre de 2003). "Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3". J. Biol. Chem.278 (36): 34253–8. PMID12815042. doi:10.1074/jbc.M304961200.
Lebrun JJ, Takabe K, Chen Y, Vale W (enero de 1999). "Roles of pathway-specific and inhibitory Smads in activin receptor signaling". Mol. Endocrinol.13 (1): 15–23. PMID9892009. doi:10.1210/mend.13.1.0218.
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL (diciembre de 2000). "Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation". Mol. Cell6 (6): 1365–75. PMID11163210. doi:10.1016/S1097-2765(00)00134-9.
Lee YS, Han JM, Son SH, Choi JW, Jeon EJ, Bae SC, Park YI, Kim S (julio de 2008). "AIMP1/p43 downregulates TGF-beta signaling via stabilization of smurf2". Biochem. Biophys. Res. Commun.371 (3): 395–400. PMID18448069. doi:10.1016/j.bbrc.2008.04.099.
Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K (julio de 2004). "Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling". J. Biol. Chem.279 (30): 31568–74. PMID15148321. doi:10.1074/jbc.M313977200.
Ferrigno O, Lallemand F, Verrecchia F, L'Hoste S, Camonis J, Atfi A, Mauviel A (julio de 2002). "Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling". Oncogene21 (32): 4879–84. PMID12118366. doi:10.1038/sj.onc.1205623.