Loots G, Locksley R, Blankespoor C, Wang Z, Miller W, Rubin E, Frazer K, Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons., in Science, vol. 288, n. 5463, 2000, pp. 136-40, PMID10753117.
SummaryArchiviato il 3 ottobre 2018 in Internet Archive.
Loots G, Locksley R, Blankespoor C, Wang Z, Miller W, Rubin E, Frazer K, Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons., in Science, vol. 288, n. 5463, 2000, pp. 136-40, PMID10753117.
SummaryArchiviato il 3 ottobre 2018 in Internet Archive.
”…a tiling array with 5-nucleotide resolution that mapped transcription activity along 10 human chromosomes revealed that an average of 10% of the genome (compared to the 1 to 2% represented by bona fide exons) corresponds to polydenylated transcripts, of which more than half do not overlap with known gene locations. Claverie J, Fewer genes, more noncoding RNA., in Science, vol. 309, n. 5740, 2005, pp. 1529-30, PMID1611064.
”…the proportion of small (50-100 bp) segments in the mammalian genome that is under (purifying) selection can be estimated to be about 5%. This proportion is much higher than can be explained by protein-coding sequences alone, implying that the genome contains many additional features (such as untranslated regions, regulatry elements, non-protein-coding genes, and chromosal structural elements) under selection for biological function.” Mouse Genome Sequencing Consortium, Initial sequencing and comparative analysis of the mouse genome., in Nature, vol. 420, n. 6915, 2002, pp. 520-62, PMID12466850.
Armstrong R, Cairns N, Myers D, Smith C, Lantos P, Rossor M, A comparison of beta-amyloid depositino in the medial temporal lobe in sporadic Alzheimer’s disease, Down’s sindrome and normal elderly brains., in Neurodegeneration, vol. 5, n. 1, 1996, pp. 35-41, PMID8731380.
Kwak HI, Gustafson T, Metz RP, Laffin B, Schedin P, Porter WW, Inibition of breast cancer growth and invasion by single-minded 2s., in Carcinogenesis, epub, PMID16840439.
”Human chromosome 2 resulted from a fusion of two ancestral chromosomes that remained separate in the chimpanzee lineare” The Chimpanzee Sequencing and Analysis Consortium, Initial sequenze of the chimpanzee genome and comparison with the human genome., in Nature, vol. 437, n. 7055, 2005, pp. 69-87, PMID16136131. ”Large-scale sequencing of the chimpanzee genome is now imminent.” Olson M, Varki A, Sequencing the chimpanzee genome: insights int human evolution and disease., in Nat Rev Genet, vol. 4, n. 1, 2003, pp. 20-8, PMID12509750.
”Our findings suggest that the deterioration of the olfactory repertoire occurred concomitant with the acquisition of full trichromatic color vision in primates.” Gilad Y, Wiebe V, Przeworski M, Lancet D, Pääbo S, Loss of olfactory receptor genes coincides with the acquistino of full trichromatic vision in primates., in PloS Biol, vol. 2, n. 1, 2004, pp. E5, PMID14737185.
Loots G, Locksley R, Blankespoor C, Wang Z, Miller W, Rubin E, Frazer K, Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons., in Science, vol. 288, n. 5463, 2000, pp. 136-40, PMID10753117.
SummaryArchiviato il 3 ottobre 2018 in Internet Archive.