Neuropatia ottica ereditaria di Leber (Italian Wikipedia)

Analysis of information sources in references of the Wikipedia article "Neuropatia ottica ereditaria di Leber" in Italian language version.

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aosonline.org

Sadun, A et al. "EPI-743 alters the natural history of progression of Leber hereditary optic neuropathy". AOS meeting. May 2011 Archiviato il 4 settembre 2011 in Internet Archive.

archive.org

WHO Model Formulary 2008, World Health Organization, 2009, p. 251, ISBN 9789241547659.
Jason Katz e Patel, Chetan, Parkland Manual of Inpatient Medicine, Dallas, TX, FA Davis, 2006, p. 903.
A "Fille du Roy" Introduced the T14484C Leber Hereditary Optic Neuropathy Mutation in French Canadians, in Am. J. Hum. Genet., vol. 77, n. 2, 2005, pp. 313–7, DOI:10.1086/432491, PMID 15954041.
A new mtDNA mutation associated with Leber hereditary optic neuroretinopathy, in Am J Hum Genet, vol. 48, n. 6, 1991, pp. 1147–1153, PMID 1674640.

arvojournals.org

iovs.arvojournals.org

J.G. Eng, D. Aggarwal e A.A. Sadun, Idebenone treatment in patients with Leber hereditary optic neuropathy, in Invest Ophthalmol Vis Sci, vol. 50, n. 13, aprile 2009. URL consultato il 22 marzo 2016.
J.A. Sahel, S. Uretsky e J.P. Combal, Preliminary safety and tolerability results of intravitreal administration of GS010, a recombinant adeno-associated viral vector serotype 2 (rAAV2/2) containing human wildtype mitochondrial NADH dehydrogenase 4 (ND4) gene in patients with Leber Hereditary Optic Neuropathy (LHON) due to the G11778A ND4 mitochondrial DNA mutation, in Invest. Ophthalmol. Vis. Sci., vol. 56, n. 7, giugno 2015, p. 1088. URL consultato il 22 marzo 2016.

asnjournals.org

jasn.asnjournals.org

D.A. Thomas, C. Stauffer e K. Zhao, Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function, in J Am Soc Nephrol, vol. 18, n. 1, gennaio 2007, pp. 213–222, DOI:10.1681/asn.2006080825, PMID 17151329. URL consultato il 22 marzo 2016.

doi.org

dx.doi.org

More evidence for non-maternal inheritance of mitochondrial DNA?, in J. Med. Genet., vol. 42, n. 12, dicembre 2005, pp. 957–60, DOI:10.1136/jmg.2005.033589, PMID 15923271.
Leber's "plus": neurological abnormalities in patients with Leber's hereditary optic neuropathy, in J. Neurol. Neurosurg. Psychiatry, vol. 59, n. 2, agosto 1995, pp. 160–4, DOI:10.1136/jnnp.59.2.160, PMID 7629530.
Differential production of superoxide by neuronal mitochondria, in BMC Neurosci, vol. 9, 2008, p. 4, DOI:10.1186/1471-2202-9-4, PMID 18182110.
Use of mitochondrial antioxidant defenses for rescue of cells with a Leber hereditary optic neuropathy-causing mutation, in Arch. Ophthalmol., vol. 125, n. 2, febbraio 2007, pp. 268–72, DOI:10.1001/archopht.125.2.268, PMID 17296905.
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids, in Invest. Ophthalmol. Vis. Sci., vol. 49, n. 2, febbraio 2008, pp. 671–6, DOI:10.1167/iovs.07-0880, PMID 18235013.
T. Klopstock, P. Yu-Wai-Man e K. Dimitriadis, A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 134, n. 9, 2011, pp. 2677–2686, DOI:10.1093/brain/awr170, ISSN 0006-8950 (WC · ACNP), PMID 21788663.
W. D. Shrader, A. Amagata e A. Barnes, Α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging, in Bioorganic & Medicinal Chemistry Letters, vol. 21, n. 12, 2011, pp. 3693–3698, DOI:10.1016/j.bmcl.2011.04.085, PMID 21600768.
Mitochondrial dysfunction as a cause of optic neuropathies, in Prog Retin Eye Res, vol. 23, n. 1, gennaio 2004, pp. 53–89, DOI:10.1016/j.preteyeres.2003.10.003, PMID 14766317.
Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?, in J Neuroophthalmol, vol. 20, n. 3, settembre 2000, pp. 166–70, DOI:10.1097/00041327-200020030-00006, PMID 11001192.
Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite, in Am. J. Ophthalmol., vol. 140, n. 3, settembre 2005, pp. 407–15, DOI:10.1016/j.ajo.2005.03.058, PMID 16083844.
Minocycline, a possible neuroprotective agent in Leber's hereditary optic neuropathy (LHON): Studies of cybrid cells bearing 11778 mutation, in Neurobiol Dis, vol. 28, n. 3, 2007, pp. 237–50, DOI:10.1016/j.nbd.2007.07.021, PMID 17822909.
Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease, in Nature, vol. 465, n. 7294, maggio 2010, pp. 82–85, Bibcode:2010Natur.465...82C, DOI:10.1038/nature08958, PMID 20393463.
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels, in PLOS ONE, vol. 6, n. 3, marzo 2011, pp. e17963, Bibcode:2011PLoSO...617963H, DOI:10.1371/journal.pone.0017963, PMID 21483849.
Klopstock T, Metz G e Yu-Wai-Man P, Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 136, n. 2, 2013, pp. e230, DOI:10.1093/brain/aws279, PMID 23388409.
G. Rudolph, K. Dimitriadis e B. Büchner, Effects of idebenone on color vision in patients with Leber hereditary optic neuropathy, in J Neuroophthalmol, vol. 33, n. 1, marzo 2013, pp. 30–36, DOI:10.1097/WNO.0b013e318272c643, PMID 23263355.
Carelli V, La Morgia C e Valentino ML, Idebenone treatment in Leber's hereditary optic neuropathy, in Brain, vol. 134, Part 9, settembre 2011, pp. e188, DOI:10.1093/brain/awr180, PMID 21810891.
R. Karanjia e A.A. Sadun, Advances in therapeutic strategies for Leber's hereditary optic neuropathy, in Expert Opinion on Orphan Drugs, vol. 3, n. 12, 2015, pp. 1439–1446, DOI:10.1517/21678707.2015.1098531.
A. Mordente, G.E. Martorana e G Minotti, Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone), in Chem Res Toxicol, vol. 11, n. 1, gennaio 1998, pp. 54–63, DOI:10.1021/tx970136j, PMID 9477226.
C. Giordano, L Iommarini e L Giordano, Efﬁcient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy, in Brain, vol. 137, Pt 2, 2013, pp. 335–353, DOI:10.1093/brain/awt343, PMID 24369379.
C. Giordano, M Montopoli e E Perli, Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy, in Brain, vol. 134, Pt 1, 2011, pp. 220–234, DOI:10.1093/brain/awq276, PMID 20943885.
A. Pisano, C Preziuso e L Iommarini, Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy, in Human Molecular Genetics, vol. 24, n. 24, 2015, pp. 6921–6931, DOI:10.1093/hmg/ddv396, PMID 26410888.
M. Fantini, S Asanad e R Karanjia, Hormone replacement therapy in Leber's hereditary optic neuropathy: Accelerated visual recovery in vivo, in Journal of Current Ophthalmology, vol. 31, 2019, pp. 102–105, DOI:10.1016/j.joco.2018.10.003, PMID 30899856.
T.J. Hwang, R Karanjia e M.N. Moraes-Filho, Natural History of Conversion of Leber's Hereditary Optic Neuropathy, in Ophthalmology, vol. 124, n. 6, 2017, pp. 843–850, DOI:10.1016/j.ophtha.2017.01.002, PMID 28196731.
C.V. Hutchinson, J.A. Walker e C Davidson, Oestrogen, ocular function and low-level vision: a review, in Journal of Endocrinology, vol. 223, n. 2, 2014, pp. R9–R18, DOI:10.1530/JOE-14-0349, PMID 25143633.
The Epidemiology of Leber Hereditary Optic Neuropathy in the North East of England, in Am. J. Hum. Genet., vol. 72, n. 2, febbraio 2003, pp. 333–9, DOI:10.1086/346066, PMID 12518276.
Epidemiology and penetrance of Leber hereditary optic neuropathy in Finland, in Eur. J. Hum. Genet., vol. 15, n. 10, ottobre 2007, pp. 1079–89, DOI:10.1038/sj.ejhg.5201828, PMID 17406640.
A "Fille du Roy" Introduced the T14484C Leber Hereditary Optic Neuropathy Mutation in French Canadians, in Am. J. Hum. Genet., vol. 77, n. 2, 2005, pp. 313–7, DOI:10.1086/432491, PMID 15954041.
Identification of an X-Chromosomal Locus and Haplotype Modulating the Phenotype of a Mitochondrial DNA Disorder, in Am. J. Hum. Genet., vol. 77, n. 6, dicembre 2005, pp. 1086–91, DOI:10.1086/498176, PMID 16380918.
<235::AID-AJMG1086>3.0.CO;2-O Leber hereditary optic neuropathy: Does heteroplasmy influence the inheritance and expression of the G11778A mitochondrial DNA mutation?, in Am. J. Med. Genet., vol. 98, n. 3, gennaio 2001, pp. 235–43, DOI:10.1002/1096-8628(20010122)98:3<235::AID-AJMG1086>3.0.CO;2-O, PMID 11169561.
Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background, in Am. J. Hum. Genet., vol. 81, n. 2, agosto 2007, pp. 228–33, DOI:10.1086/519394, PMID 17668373.
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy, in Science, vol. 242, n. 4884, dicembre 1988, pp. 1427–30, Bibcode:1988Sci...242.1427W, DOI:10.1126/science.3201231, PMID 3201231.
An ND-6 mitochondrial DNA mutation associated with Leber hereditary optic neuropathy, in Biochem Biophys Res Commun, vol. 187, n. 3, 1992, pp. 1551–1557, DOI:10.1016/0006-291x(92)90479-5, PMID 1417830.
A.V. Birk, S. Liu e Y. Soong, The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin, in J Am Soc Nephrol, vol. 24, n. 8, luglio 2013, pp. 1250–61, DOI:10.1681/ASN.2012121216, PMID 23813215.
D.A. Thomas, C. Stauffer e K. Zhao, Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function, in J Am Soc Nephrol, vol. 18, n. 1, gennaio 2007, pp. 213–222, DOI:10.1681/asn.2006080825, PMID 17151329. URL consultato il 22 marzo 2016.
Brown DA, Hale SL e Baines CP, Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia, in J Cardiovasc Pharmacol Ther, vol. 19, n. 1, gennaio 2014, pp. 121–132, DOI:10.1177/1074248413508003, PMID 24288396.

doi.org

David Bargiela, Patrick F Chinnery, Mitochondria in neuroinflammation – Multiple sclerosis (MS), leber hereditary optic neuropathy (LHON) and LHON-MS, https://doi.org/10.1016/j.neulet.2017.06.051

harvard.edu

adsabs.harvard.edu

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease, in Nature, vol. 465, n. 7294, maggio 2010, pp. 82–85, Bibcode:2010Natur.465...82C, DOI:10.1038/nature08958, PMID 20393463.
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels, in PLOS ONE, vol. 6, n. 3, marzo 2011, pp. e17963, Bibcode:2011PLoSO...617963H, DOI:10.1371/journal.pone.0017963, PMID 21483849.
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy, in Science, vol. 242, n. 4884, dicembre 1988, pp. 1427–30, Bibcode:1988Sci...242.1427W, DOI:10.1126/science.3201231, PMID 3201231.

mayoclinic.com

Mayo Clinic: Multiple Sclerosis

mcw.edu

Wisconsin near infrared trial Archiviato il 15 maggio 2008 in Internet Archive.

molvis.org

X-Inactivation patterns in females harboring mtDNA mutations that cause Leber hereditary optic neuropathy, in Mol. Vis., vol. 13, 2007, pp. 2339–43, PMID 18199976.

ncl.ac.uk

lhon.ncl.ac.uk

Clinical Idebenone trial recruiting at Newcastle University UK http://lhon.ncl.ac.uk Archiviato il 7 marzo 2021 in Internet Archive.

nih.gov

ncbi.nlm.nih.gov

More evidence for non-maternal inheritance of mitochondrial DNA?, in J. Med. Genet., vol. 42, n. 12, dicembre 2005, pp. 957–60, DOI:10.1136/jmg.2005.033589, PMID 15923271.
Leber's "plus": neurological abnormalities in patients with Leber's hereditary optic neuropathy, in J. Neurol. Neurosurg. Psychiatry, vol. 59, n. 2, agosto 1995, pp. 160–4, DOI:10.1136/jnnp.59.2.160, PMID 7629530.
Differential production of superoxide by neuronal mitochondria, in BMC Neurosci, vol. 9, 2008, p. 4, DOI:10.1186/1471-2202-9-4, PMID 18182110.
Use of mitochondrial antioxidant defenses for rescue of cells with a Leber hereditary optic neuropathy-causing mutation, in Arch. Ophthalmol., vol. 125, n. 2, febbraio 2007, pp. 268–72, DOI:10.1001/archopht.125.2.268, PMID 17296905.
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids, in Invest. Ophthalmol. Vis. Sci., vol. 49, n. 2, febbraio 2008, pp. 671–6, DOI:10.1167/iovs.07-0880, PMID 18235013.
NCBI, https://www.ncbi.nlm.nih.gov/books/NBK1174/ Titolo mancante per url url (aiuto). URL consultato il 25 febbraio 2018.
T. Klopstock, P. Yu-Wai-Man e K. Dimitriadis, A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 134, n. 9, 2011, pp. 2677–2686, DOI:10.1093/brain/awr170, ISSN 0006-8950 (WC · ACNP), PMID 21788663.
W. D. Shrader, A. Amagata e A. Barnes, Α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging, in Bioorganic & Medicinal Chemistry Letters, vol. 21, n. 12, 2011, pp. 3693–3698, DOI:10.1016/j.bmcl.2011.04.085, PMID 21600768.
Subclinical carriers and conversions in Leber hereditary optic neuropathy: A prospective psychophysical study, in Trans Am Ophthalmol Soc, vol. 104, 2006, pp. 51–61, PMID 17471325.
Mitochondrial dysfunction as a cause of optic neuropathies, in Prog Retin Eye Res, vol. 23, n. 1, gennaio 2004, pp. 53–89, DOI:10.1016/j.preteyeres.2003.10.003, PMID 14766317.
Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?, in J Neuroophthalmol, vol. 20, n. 3, settembre 2000, pp. 166–70, DOI:10.1097/00041327-200020030-00006, PMID 11001192.
Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite, in Am. J. Ophthalmol., vol. 140, n. 3, settembre 2005, pp. 407–15, DOI:10.1016/j.ajo.2005.03.058, PMID 16083844.
Minocycline, a possible neuroprotective agent in Leber's hereditary optic neuropathy (LHON): Studies of cybrid cells bearing 11778 mutation, in Neurobiol Dis, vol. 28, n. 3, 2007, pp. 237–50, DOI:10.1016/j.nbd.2007.07.021, PMID 17822909.
Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease, in Nature, vol. 465, n. 7294, maggio 2010, pp. 82–85, Bibcode:2010Natur.465...82C, DOI:10.1038/nature08958, PMID 20393463.
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels, in PLOS ONE, vol. 6, n. 3, marzo 2011, pp. e17963, Bibcode:2011PLoSO...617963H, DOI:10.1371/journal.pone.0017963, PMID 21483849.
Klopstock T, Metz G e Yu-Wai-Man P, Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 136, n. 2, 2013, pp. e230, DOI:10.1093/brain/aws279, PMID 23388409.
G. Rudolph, K. Dimitriadis e B. Büchner, Effects of idebenone on color vision in patients with Leber hereditary optic neuropathy, in J Neuroophthalmol, vol. 33, n. 1, marzo 2013, pp. 30–36, DOI:10.1097/WNO.0b013e318272c643, PMID 23263355.
Carelli V, La Morgia C e Valentino ML, Idebenone treatment in Leber's hereditary optic neuropathy, in Brain, vol. 134, Part 9, settembre 2011, pp. e188, DOI:10.1093/brain/awr180, PMID 21810891.
A. Mordente, G.E. Martorana e G Minotti, Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone), in Chem Res Toxicol, vol. 11, n. 1, gennaio 1998, pp. 54–63, DOI:10.1021/tx970136j, PMID 9477226.
C. Giordano, L Iommarini e L Giordano, Efﬁcient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy, in Brain, vol. 137, Pt 2, 2013, pp. 335–353, DOI:10.1093/brain/awt343, PMID 24369379.
C. Giordano, M Montopoli e E Perli, Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy, in Brain, vol. 134, Pt 1, 2011, pp. 220–234, DOI:10.1093/brain/awq276, PMID 20943885.
A. Pisano, C Preziuso e L Iommarini, Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy, in Human Molecular Genetics, vol. 24, n. 24, 2015, pp. 6921–6931, DOI:10.1093/hmg/ddv396, PMID 26410888.
M. Fantini, S Asanad e R Karanjia, Hormone replacement therapy in Leber's hereditary optic neuropathy: Accelerated visual recovery in vivo, in Journal of Current Ophthalmology, vol. 31, 2019, pp. 102–105, DOI:10.1016/j.joco.2018.10.003, PMID 30899856.
T.J. Hwang, R Karanjia e M.N. Moraes-Filho, Natural History of Conversion of Leber's Hereditary Optic Neuropathy, in Ophthalmology, vol. 124, n. 6, 2017, pp. 843–850, DOI:10.1016/j.ophtha.2017.01.002, PMID 28196731.
C.V. Hutchinson, J.A. Walker e C Davidson, Oestrogen, ocular function and low-level vision: a review, in Journal of Endocrinology, vol. 223, n. 2, 2014, pp. R9–R18, DOI:10.1530/JOE-14-0349, PMID 25143633.
The Epidemiology of Leber Hereditary Optic Neuropathy in the North East of England, in Am. J. Hum. Genet., vol. 72, n. 2, febbraio 2003, pp. 333–9, DOI:10.1086/346066, PMID 12518276.
Epidemiology and penetrance of Leber hereditary optic neuropathy in Finland, in Eur. J. Hum. Genet., vol. 15, n. 10, ottobre 2007, pp. 1079–89, DOI:10.1038/sj.ejhg.5201828, PMID 17406640.
A "Fille du Roy" Introduced the T14484C Leber Hereditary Optic Neuropathy Mutation in French Canadians, in Am. J. Hum. Genet., vol. 77, n. 2, 2005, pp. 313–7, DOI:10.1086/432491, PMID 15954041.
X-Inactivation patterns in females harboring mtDNA mutations that cause Leber hereditary optic neuropathy, in Mol. Vis., vol. 13, 2007, pp. 2339–43, PMID 18199976.
Identification of an X-Chromosomal Locus and Haplotype Modulating the Phenotype of a Mitochondrial DNA Disorder, in Am. J. Hum. Genet., vol. 77, n. 6, dicembre 2005, pp. 1086–91, DOI:10.1086/498176, PMID 16380918.
<235::AID-AJMG1086>3.0.CO;2-O Leber hereditary optic neuropathy: Does heteroplasmy influence the inheritance and expression of the G11778A mitochondrial DNA mutation?, in Am. J. Med. Genet., vol. 98, n. 3, gennaio 2001, pp. 235–43, DOI:10.1002/1096-8628(20010122)98:3<235::AID-AJMG1086>3.0.CO;2-O, PMID 11169561.
Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background, in Am. J. Hum. Genet., vol. 81, n. 2, agosto 2007, pp. 228–33, DOI:10.1086/519394, PMID 17668373.
Leber's optic atrophy, a possible example of maternal inheritance, in American Journal of Human Genetics, vol. 24, n. 3, maggio 1972, pp. 348–9, PMID 5063796.
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy, in Science, vol. 242, n. 4884, dicembre 1988, pp. 1427–30, Bibcode:1988Sci...242.1427W, DOI:10.1126/science.3201231, PMID 3201231.
A new mtDNA mutation associated with Leber hereditary optic neuroretinopathy, in Am J Hum Genet, vol. 48, n. 6, 1991, pp. 1147–1153, PMID 1674640.
An ND-6 mitochondrial DNA mutation associated with Leber hereditary optic neuropathy, in Biochem Biophys Res Commun, vol. 187, n. 3, 1992, pp. 1551–1557, DOI:10.1016/0006-291x(92)90479-5, PMID 1417830.
A.V. Birk, S. Liu e Y. Soong, The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin, in J Am Soc Nephrol, vol. 24, n. 8, luglio 2013, pp. 1250–61, DOI:10.1681/ASN.2012121216, PMID 23813215.
D.A. Thomas, C. Stauffer e K. Zhao, Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function, in J Am Soc Nephrol, vol. 18, n. 1, gennaio 2007, pp. 213–222, DOI:10.1681/asn.2006080825, PMID 17151329. URL consultato il 22 marzo 2016.
Brown DA, Hale SL e Baines CP, Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia, in J Cardiovasc Pharmacol Ther, vol. 19, n. 1, gennaio 2014, pp. 121–132, DOI:10.1177/1074248413508003, PMID 24288396.

clinicaltrials.nlm.nih.gov

Clinical Curcurmin trial recruiting at ClinicalTrials.nlm.nih.gov Archiviato il 13 febbraio 2009 in Internet Archive.

oadoi.org

More evidence for non-maternal inheritance of mitochondrial DNA?, in J. Med. Genet., vol. 42, n. 12, dicembre 2005, pp. 957–60, DOI:10.1136/jmg.2005.033589, PMID 15923271.
Leber's "plus": neurological abnormalities in patients with Leber's hereditary optic neuropathy, in J. Neurol. Neurosurg. Psychiatry, vol. 59, n. 2, agosto 1995, pp. 160–4, DOI:10.1136/jnnp.59.2.160, PMID 7629530.
Differential production of superoxide by neuronal mitochondria, in BMC Neurosci, vol. 9, 2008, p. 4, DOI:10.1186/1471-2202-9-4, PMID 18182110.
Use of mitochondrial antioxidant defenses for rescue of cells with a Leber hereditary optic neuropathy-causing mutation, in Arch. Ophthalmol., vol. 125, n. 2, febbraio 2007, pp. 268–72, DOI:10.1001/archopht.125.2.268, PMID 17296905.
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids, in Invest. Ophthalmol. Vis. Sci., vol. 49, n. 2, febbraio 2008, pp. 671–6, DOI:10.1167/iovs.07-0880, PMID 18235013.
T. Klopstock, P. Yu-Wai-Man e K. Dimitriadis, A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 134, n. 9, 2011, pp. 2677–2686, DOI:10.1093/brain/awr170, ISSN 0006-8950 (WC · ACNP), PMID 21788663.
W. D. Shrader, A. Amagata e A. Barnes, Α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging, in Bioorganic & Medicinal Chemistry Letters, vol. 21, n. 12, 2011, pp. 3693–3698, DOI:10.1016/j.bmcl.2011.04.085, PMID 21600768.
Mitochondrial dysfunction as a cause of optic neuropathies, in Prog Retin Eye Res, vol. 23, n. 1, gennaio 2004, pp. 53–89, DOI:10.1016/j.preteyeres.2003.10.003, PMID 14766317.
Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?, in J Neuroophthalmol, vol. 20, n. 3, settembre 2000, pp. 166–70, DOI:10.1097/00041327-200020030-00006, PMID 11001192.
Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite, in Am. J. Ophthalmol., vol. 140, n. 3, settembre 2005, pp. 407–15, DOI:10.1016/j.ajo.2005.03.058, PMID 16083844.
Minocycline, a possible neuroprotective agent in Leber's hereditary optic neuropathy (LHON): Studies of cybrid cells bearing 11778 mutation, in Neurobiol Dis, vol. 28, n. 3, 2007, pp. 237–50, DOI:10.1016/j.nbd.2007.07.021, PMID 17822909.
Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease, in Nature, vol. 465, n. 7294, maggio 2010, pp. 82–85, Bibcode:2010Natur.465...82C, DOI:10.1038/nature08958, PMID 20393463.
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels, in PLOS ONE, vol. 6, n. 3, marzo 2011, pp. e17963, Bibcode:2011PLoSO...617963H, DOI:10.1371/journal.pone.0017963, PMID 21483849.
Klopstock T, Metz G e Yu-Wai-Man P, Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 136, n. 2, 2013, pp. e230, DOI:10.1093/brain/aws279, PMID 23388409.
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T. Klopstock, P. Yu-Wai-Man e K. Dimitriadis, A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 134, n. 9, 2011, pp. 2677–2686, DOI:10.1093/brain/awr170, ISSN 0006-8950 (WC · ACNP), PMID 21788663.

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cardiac arrythmia, su heart-disease.health-cares.net (archiviato dall'url originale il 30 gennaio 2020).
Clinical Idebenone trial recruiting at Newcastle University UK http://lhon.ncl.ac.uk Archiviato il 7 marzo 2021 in Internet Archive.
Sadun, A et al. "EPI-743 alters the natural history of progression of Leber hereditary optic neuropathy". AOS meeting. May 2011 Archiviato il 4 settembre 2011 in Internet Archive.
Clinical Curcurmin trial recruiting at ClinicalTrials.nlm.nih.gov Archiviato il 13 febbraio 2009 in Internet Archive.
Wisconsin near infrared trial Archiviato il 15 maggio 2008 in Internet Archive.

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T. Klopstock, P. Yu-Wai-Man e K. Dimitriadis, A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy, in Brain, vol. 134, n. 9, 2011, pp. 2677–2686, DOI:10.1093/brain/awr170, ISSN 0006-8950 (WC · ACNP), PMID 21788663.