JR Bertino, Folate antagonists: toward improving the therapeutic index and development of new analogs, in J Clin Pharmacol., vol. 30, n. 4, Apr 1990, pp. 291-5, PMID 2140369.
JR. Bertino, WL. Sawicki; BA. Moroson; AR. Cashmore; EF. Elslager, 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline (tmq), a potent non-classical folate antagonist inhibitor--I effect on dihydrofolate reductase and growth of rodent tumors in vitro and in vivo., in Biochem Pharmacol, vol. 28, n. 12, Giu 1979, pp. 1983-7, PMID 454469.
RC. Jackson, DW. Fry; TJ. Boritzki; JA. Besserer; WR. Leopold; BJ. Sloan; EF. Elslager, Biochemical pharmacology of the lipophilic antifolate, trimetrexate., in Adv Enzyme Regul, vol. 22, 1984, pp. 187-206, PMID 6236675.
EC. Weir, AR. Cashmore; RN. Dreyer; ML. Graham; N. Hsiao; BA. Moroson; WL. Sawicki; JR. Bertino, Pharmacology and toxicity of a potent nonclassical 2,4-diamino quinazoline folate antagonist, trimetrexate, in normal dogs., in Cancer Res, vol. 42, n. 5, Mag 1982, pp. 1696-702, PMID 6461409.
JL Marshall, RJ DeLap, Clinical pharmacokinetics and pharmacology of trimetrexate, in Clin Pharmacokinet., vol. 26, n. 3, Mar 1994, pp. 190-200, PMID 8194282.
DG. Haller, Trimetrexate: experience with solid tumors., in Semin Oncol., vol. 24, (5 Suppl 18), Ott 1997, pp. S18-71-S18-76, PMID 9420024.
AA Garcia, L Leichman; J Baranda; L Pandit; HJ Lenz; CG Leichman, Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer., in Int J Gastrointest Cancer, vol. 34, n. 2-3, 2003, pp. 79-86, PMID 15361639.
H. Diddens, D. Niethammer; RC. Jackson, Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate., in Cancer Res, vol. 43, n. 11, Nov 1983, pp. 5286-92, PMID 6225514.
A. Pappo, R. Dubowy; Y. Ravindranath; C. Alvarado; S. Rao; VM. Whitehead; R. Vega; B. Kamen; T. Vietti, Phase II trial of trimetrexate in the treatment of recurrent childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study., in J Natl Cancer Inst, vol. 82, n. 20, Ott 1990, pp. 1641-2, PMID 2145440.
FR. Sattler, CJ. Allegra; TD. Verdegem; B. Akil; CU. Tuazon; C. Hughlett; D. Ogata-Arakaki; J. Feinberg; J. Shelhamer; HC. Lane, Trimetrexate-leucovorin dosage evaluation study for treatment of Pneumocystis carinii pneumonia., in J Infect Dis, vol. 161, n. 1, Gen 1990, pp. 91-6, PMID 2136905.
GW. Amsden, SF. Kowalsky; GD. Morse, Trimetrexate for Pneumocystis carinii pneumonia in patients with AIDS., in Ann Pharmacother, vol. 26, n. 2, Feb 1992, pp. 218-26, PMID 1532518.
B. Fulton, AJ. Wagstaff; D. McTavish, Trimetrexate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of Pneumocystis carinii pneumonia., in Drugs, vol. 49, n. 4, Apr 1995, pp. 563-76, PMID 7789290.