Toyn J (May 2015). “What lessons can be learned from failed Alzheimer's disease trials?”. Expert Review of Clinical Pharmacology8 (3): 267–9. doi:10.1586/17512433.2015.1034690. PMID25860157.
Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A (September 2016). “The antibody aducanumab reduces Aβ plaques in Alzheimer's disease”. Nature537 (7618): 50–6. Bibcode: 2016Natur.537...50S. doi:10.1038/nature19323. PMID27582220.
Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A (September 2016). “The antibody aducanumab reduces Aβ plaques in Alzheimer's disease”. Nature537 (7618): 50–6. Bibcode: 2016Natur.537...50S. doi:10.1038/nature19323. PMID27582220.
Toyn J (May 2015). “What lessons can be learned from failed Alzheimer's disease trials?”. Expert Review of Clinical Pharmacology8 (3): 267–9. doi:10.1586/17512433.2015.1034690. PMID25860157.
Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A (September 2016). “The antibody aducanumab reduces Aβ plaques in Alzheimer's disease”. Nature537 (7618): 50–6. Bibcode: 2016Natur.537...50S. doi:10.1038/nature19323. PMID27582220.
Herper, Matthew (2019年10月22日). “In shocking reversal, Biogen to submit Alzheimer's drug for approval”. STAT. 2019年10月22日閲覧。 “"In one study, called Emerge, patients on the high-dose aducanumab had a 23% reduction in their rate of decline compared to those on placebo; those who were on the low dose were 11% lower than placebo, but that result was not statistically significant. But in the second trial, Engage, the decrease was only 2% in patients on the high dose."”