Rangaswami H, Bulbule A, Kundu GC (February 2006). “Osteopontin: role in cell signaling and cancer progression”. Trends in Cell Biology16 (2): 79–87. doi:10.1016/j.tcb.2005.12.005. PMID16406521.
Crosby AH, Edwards SJ, Murray JC, Dixon MJ (May 1995). “Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II”. Genomics27 (1): 155–160. doi:10.1006/geno.1995.1018. PMID7665163.
Barros NM, Hoac B, Neves RL, Addison WN, Assis DM, Murshed M, Carmona AK, McKee MD (March 2013). “Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia”. Journal of Bone and Mineral Research28 (3): 688–699. doi:10.1002/jbmr.1766. PMID22991293.
Banerjee A, Apte UM, Smith R, Ramaiah SK (March 2006). “Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease”. The Journal of Pathology208 (4): 473–485. doi:10.1002/path.1917. PMID16440289.
Zohar R, Suzuki N, Suzuki K, Arora P, Glogauer M, McCulloch CA, Sodek J (July 2000). “Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration”. Journal of Cellular Physiology184 (1): 118–130. doi:10.1002/(SICI)1097-4652(200007)184:1<118::AID-JCP13>3.0.CO;2-Y. PMID10825241.
Suzuki K, Zhu B, Rittling SR, Denhardt DT, Goldberg HA, McCulloch CA, Sodek J (August 2002). “Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts”. Journal of Bone and Mineral Research17 (8): 1486–1497. doi:10.1359/jbmr.2002.17.8.1486. PMID12162503.
Zhu B, Suzuki K, Goldberg HA, Rittling SR, Denhardt DT, McCulloch CA, Sodek J (January 2004). “Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin”. Journal of Cellular Physiology198 (1): 155–167. doi:10.1002/jcp.10394. PMID14584055.
Junaid A, Moon MC, Harding GE, Zahradka P (February 2007). “Osteopontin localizes to the nucleus of 293 cells and associates with polo-like kinase-1”. American Journal of Physiology. Cell Physiology292 (2): C919–C926. doi:10.1152/ajpcell.00477.2006. PMID17005603.
He B, Mirza M, Weber GF (April 2006). “An osteopontin splice variant induces anchorage independence in human breast cancer cells”. Oncogene25 (15): 2192–2202. doi:10.1038/sj.onc.1209248. PMID16288209.
Mirza M, Shaughnessy E, Hurley JK, Vanpatten KA, Pestano GA, He B, Weber GF (February 2008). “Osteopontin-c is a selective marker of breast cancer”. International Journal of Cancer122 (4): 889–897. doi:10.1002/ijc.23204. PMID17960616.
Uaesoontrachoon K, Yoo HJ, Tudor EM, Pike RN, Mackie EJ, Pagel CN (April 2008). “Osteopontin and skeletal muscle myoblasts: association with muscle regeneration and regulation of myoblast function in vitro”. The International Journal of Biochemistry & Cell Biology40 (10): 2303–2314. doi:10.1016/j.biocel.2008.03.020. PMID18490187.
Merry K, Dodds R, Littlewood A, Gowen M (April 1993). “Expression of osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone”. Journal of Cell Science104 (4): 1013–1020. doi:10.1242/jcs.104.4.1013. PMID8314886.
Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B (January 2002). “The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation”. Cell108 (1): 17–29. doi:10.1016/S0092-8674(01)00622-5. PMID11792318.
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G (May 1997). “Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation”. Cell89 (5): 747–754. doi:10.1016/S0092-8674(00)80257-3. PMID9182762.
Prince CW, Butler WT (September 1987). “1,25-Dihydroxyvitamin D3 regulates the biosynthesis of osteopontin, a bone-derived cell attachment protein, in clonal osteoblast-like osteosarcoma cells”. Collagen and Related Research7 (4): 305–313. doi:10.1016/s0174-173x(87)80036-5. PMID3478171.
Pereira TA, Vaz de Melo Trindade G, Trindade Santos E, Pereira FE, Souza MM (May 2021). “Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni”. International Journal for Parasitology51 (6): 437–440. doi:10.1016/j.ijpara.2020.11.002. PMID33493521.
Guo H, Cai CQ, Schroeder RA, Kuo PC (January 2001). “Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages”. Journal of Immunology166 (2): 1079–1086. doi:10.4049/jimmunol.166.2.1079. PMID11145688.
Ricardo SD, Franzoni DF, Roesener CD, Crisman JM, Diamond JR (May 2000). “Angiotensinogen and AT(1) antisense inhibition of osteopontin translation in rat proximal tubular cells”. American Journal of Physiology. Renal Physiology278 (5): F708–F716. doi:10.1152/ajprenal.2000.278.5.F708. PMID10807582.
Hullinger TG, Pan Q, Viswanathan HL, Somerman MJ (January 2001). “TGFbeta and BMP-2 activation of the OPN promoter: roles of smad- and hox-binding elements”. Experimental Cell Research262 (1): 69–74. doi:10.1006/excr.2000.5074. PMID11120606.
Sodhi CP, Phadke SA, Batlle D, Sahai A (April 2001). “Hypoxia and high glucose cause exaggerated mesangial cell growth and collagen synthesis: role of osteopontin”. American Journal of Physiology. Renal Physiology280 (4): F667–F674. doi:10.1152/ajprenal.2001.280.4.F667. PMID11249858.
Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R (September 2006). “Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death”. Journal of Cellular Physiology208 (3): 629–639. doi:10.1002/jcp.20701. PMID16741956.
Fisher LW, Fedarko NS (2003). “Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins”. Connective Tissue Research44 (Suppl 1): 33–40. doi:10.1080/03008200390152061. PMID12952171.
Addison WN, Nakano Y, Loisel T, Crine P, McKee MD (October 2008). “MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM”. Journal of Bone and Mineral Research23 (10): 1638–1649. doi:10.1359/jbmr.080601. PMID18597632.
Addison WN, Masica DL, Gray JJ, McKee MD (April 2010). “Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage”. Journal of Bone and Mineral Research25 (4): 695–705. doi:10.1359/jbmr.090832. PMID19775205.
Hunter GK, O'Young J, Grohe B, Karttunen M, Goldberg HA (December 2010). “The flexible polyelectrolyte hypothesis of protein-biomineral interaction”. Langmuir26 (24): 18639–18646. doi:10.1021/la100401r. PMID20527831.
McKee MD, Nanci A (May 1995). “Postembedding colloidal-gold immunocytochemistry of noncollagenous extracellular matrix proteins in mineralized tissues”. Microscopy Research and Technique31 (1): 44–62. doi:10.1002/jemt.1070310105. PMID7626799.
Takemura T, Sakagami M, Nakase T, Kubo T, Kitamura Y, Nomura S (September 1994). “Localization of osteopontin in the otoconial organs of adult rats”. Hearing Research79 (1–2): 99–104. doi:10.1016/0378-5955(94)90131-7. PMID7806488.
Hincke MT, Nys Y, Gautron J, Mann K, Rodriguez-Navarro AB, McKee MD (January 2012). “The eggshell: structure, composition and mineralization”. Frontiers in Bioscience17 (4): 1266–1280. doi:10.2741/3985. PMID22201802.
McKee MD, Nanci A, Khan SR (December 1995). “Ultrastructural immunodetection of osteopontin and osteocalcin as major matrix components of renal calculi”. Journal of Bone and Mineral Research10 (12): 1913–1929. doi:10.1002/jbmr.5650101211. PMID8619372.
O'Young J, Chirico S, Al Tarhuni N, Grohe B, Karttunen M, Goldberg HA, Hunter GK (2009). “Phosphorylation of osteopontin peptides mediates adsorption to and incorporation into calcium oxalate crystals”. Cells Tissues Organs189 (1–4): 51–55. doi:10.1159/000151724. PMID18728346.
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McKee MD, Buss DJ, Reznikov N (March 2022). “Mineral tessellation in bone and the stenciling principle for extracellular matrix mineralization”. Journal of Structural Biology214 (1): 107823. doi:10.1016/j.jsb.2021.107823. PMID34915130.
Boukpessi T, Hoac B, Coyac BR, Leger T, Garcia C, Wicart P, Whyte MP, Glorieux FH, Linglart A, Chaussain C, McKee MD (February 2017). “Osteopontin and the dento-osseous pathobiology of X-linked hypophosphatemia”. Bone95: 151–161. doi:10.1016/j.bone.2016.11.019. PMID27884786.
Reznikov N, Hoac B, Buss DJ, Addison WN, Barros NM, McKee MD (September 2020). “Biological stenciling of mineralization in the skeleton: Local enzymatic removal of inhibitors in the extracellular matrix”. Bone138: 115447. doi:10.1016/j.bone.2020.115447. PMID32454257.
McKee MD, Addison WN, Kaartinen MT (2005). “Hierarchies of extracellular matrix and mineral organization in bone of the craniofacial complex and skeleton”. Cells Tissues Organs181 (3–4): 176–188. doi:10.1159/000091379. PMID16612083.
Kaartinen MT, Murshed M, Karsenty G, McKee MD (April 2007). “Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice”. The Journal of Histochemistry and Cytochemistry55 (4): 375–386. doi:10.1369/jhc.6A7087.2006. PMID17189522.
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McKee MD, Nanci A (1996). “Osteopontin: an interfacial extracellular matrix protein in mineralized tissues”. Connective Tissue Research35 (1–4): 197–205. doi:10.3109/03008209609029192. PMID9084658.
Nagasaka A, Matsue H, Matsushima H, Aoki R, Nakamura Y, Kambe N, Kon S, Uede T, Shimada S (February 2008). “Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells”. European Journal of Immunology38 (2): 489–499. doi:10.1002/eji.200737057. PMID18200503.
Apte UM, Banerjee A, McRee R, Wellberg E, Ramaiah SK (August 2005). “Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis”. Toxicology and Applied Pharmacology207 (1): 25–38. doi:10.1016/j.taap.2004.12.018. PMID15885730.
Ohshima S, Kobayashi H, Yamaguchi N, Nishioka K, Umeshita-Sasai M, Mima T, Nomura S, Kon S, Inobe M, Uede T, Saeki Y (April 2002). “Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: possible involvement of osteopontin in bone destruction in arthritis”. Arthritis and Rheumatism46 (4): 1094–1101. doi:10.1002/art.10143. PMID11953989.
Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C (August 2004). “Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis”. Arthritis and Rheumatism50 (8): 2685–2694. doi:10.1002/art.20381. PMID15334485.
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L (November 2001). “The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease”. Science294 (5547): 1731–1735. Bibcode: 2001Sci...294.1731C. doi:10.1126/science.1062960. PMID11721059.
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Samitas K, Zervas E, Vittorakis S, Semitekolou M, Alissafi T, Bossios A, Gogos H, Economidou E, Lötvall J, Xanthou G, Panoutsakopoulou V, Gaga M (February 2011). “Osteopontin expression and relation to disease severity in human asthma”. The European Respiratory Journal37 (2): 331–341. doi:10.1183/09031936.00017810. PMID20562127.
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El Deeb S, Abdelnaby R, Khachab A, Bläsius K, Tingart M, Rath B (July 2016). “Osteopontin as a biochemical marker and severity indicator for idiopathic hip osteoarthritis”. Hip International26 (4): 397–403. doi:10.5301/hipint.5000361. PMID27229171.
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Rangaswami H, Bulbule A, Kundu GC (February 2006). “Osteopontin: role in cell signaling and cancer progression”. Trends in Cell Biology16 (2): 79–87. doi:10.1016/j.tcb.2005.12.005. PMID16406521.
Crosby AH, Edwards SJ, Murray JC, Dixon MJ (May 1995). “Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II”. Genomics27 (1): 155–160. doi:10.1006/geno.1995.1018. PMID7665163.
Barros NM, Hoac B, Neves RL, Addison WN, Assis DM, Murshed M, Carmona AK, McKee MD (March 2013). “Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia”. Journal of Bone and Mineral Research28 (3): 688–699. doi:10.1002/jbmr.1766. PMID22991293.
Seiffge D (December 1996). “Protective effects of monoclonal antibody to VLA-4 on leukocyte adhesion and course of disease in adjuvant arthritis in rats”. The Journal of Rheumatology23 (12): 2086–2091. PMID8970045.
Banerjee A, Apte UM, Smith R, Ramaiah SK (March 2006). “Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease”. The Journal of Pathology208 (4): 473–485. doi:10.1002/path.1917. PMID16440289.
Zohar R, Suzuki N, Suzuki K, Arora P, Glogauer M, McCulloch CA, Sodek J (July 2000). “Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration”. Journal of Cellular Physiology184 (1): 118–130. doi:10.1002/(SICI)1097-4652(200007)184:1<118::AID-JCP13>3.0.CO;2-Y. PMID10825241.
Suzuki K, Zhu B, Rittling SR, Denhardt DT, Goldberg HA, McCulloch CA, Sodek J (August 2002). “Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts”. Journal of Bone and Mineral Research17 (8): 1486–1497. doi:10.1359/jbmr.2002.17.8.1486. PMID12162503.
Zhu B, Suzuki K, Goldberg HA, Rittling SR, Denhardt DT, McCulloch CA, Sodek J (January 2004). “Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin”. Journal of Cellular Physiology198 (1): 155–167. doi:10.1002/jcp.10394. PMID14584055.
Junaid A, Moon MC, Harding GE, Zahradka P (February 2007). “Osteopontin localizes to the nucleus of 293 cells and associates with polo-like kinase-1”. American Journal of Physiology. Cell Physiology292 (2): C919–C926. doi:10.1152/ajpcell.00477.2006. PMID17005603.
He B, Mirza M, Weber GF (April 2006). “An osteopontin splice variant induces anchorage independence in human breast cancer cells”. Oncogene25 (15): 2192–2202. doi:10.1038/sj.onc.1209248. PMID16288209.
Mirza M, Shaughnessy E, Hurley JK, Vanpatten KA, Pestano GA, He B, Weber GF (February 2008). “Osteopontin-c is a selective marker of breast cancer”. International Journal of Cancer122 (4): 889–897. doi:10.1002/ijc.23204. PMID17960616.
Uaesoontrachoon K, Yoo HJ, Tudor EM, Pike RN, Mackie EJ, Pagel CN (April 2008). “Osteopontin and skeletal muscle myoblasts: association with muscle regeneration and regulation of myoblast function in vitro”. The International Journal of Biochemistry & Cell Biology40 (10): 2303–2314. doi:10.1016/j.biocel.2008.03.020. PMID18490187.
Merry K, Dodds R, Littlewood A, Gowen M (April 1993). “Expression of osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone”. Journal of Cell Science104 (4): 1013–1020. doi:10.1242/jcs.104.4.1013. PMID8314886.
Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B (January 2002). “The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation”. Cell108 (1): 17–29. doi:10.1016/S0092-8674(01)00622-5. PMID11792318.
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G (May 1997). “Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation”. Cell89 (5): 747–754. doi:10.1016/S0092-8674(00)80257-3. PMID9182762.
Yucha C, Guthrie D (December 2003). “Renal homeostasis of calcium”. Nephrology Nursing Journal30 (6): 755–764. PMID14730782.
Prince CW, Butler WT (September 1987). “1,25-Dihydroxyvitamin D3 regulates the biosynthesis of osteopontin, a bone-derived cell attachment protein, in clonal osteoblast-like osteosarcoma cells”. Collagen and Related Research7 (4): 305–313. doi:10.1016/s0174-173x(87)80036-5. PMID3478171.
Chang PL, Prince CW (April 1991). “1 alpha,25-dihydroxyvitamin D3 stimulates synthesis and secretion of nonphosphorylated osteopontin (secreted phosphoprotein 1) in mouse JB6 epidermal cells”. Cancer Research51 (8): 2144–2150. PMID2009532.
Pereira TA, Vaz de Melo Trindade G, Trindade Santos E, Pereira FE, Souza MM (May 2021). “Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni”. International Journal for Parasitology51 (6): 437–440. doi:10.1016/j.ijpara.2020.11.002. PMID33493521.
Guo H, Cai CQ, Schroeder RA, Kuo PC (January 2001). “Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages”. Journal of Immunology166 (2): 1079–1086. doi:10.4049/jimmunol.166.2.1079. PMID11145688.
Ricardo SD, Franzoni DF, Roesener CD, Crisman JM, Diamond JR (May 2000). “Angiotensinogen and AT(1) antisense inhibition of osteopontin translation in rat proximal tubular cells”. American Journal of Physiology. Renal Physiology278 (5): F708–F716. doi:10.1152/ajprenal.2000.278.5.F708. PMID10807582.
Hullinger TG, Pan Q, Viswanathan HL, Somerman MJ (January 2001). “TGFbeta and BMP-2 activation of the OPN promoter: roles of smad- and hox-binding elements”. Experimental Cell Research262 (1): 69–74. doi:10.1006/excr.2000.5074. PMID11120606.
Sodhi CP, Phadke SA, Batlle D, Sahai A (April 2001). “Hypoxia and high glucose cause exaggerated mesangial cell growth and collagen synthesis: role of osteopontin”. American Journal of Physiology. Renal Physiology280 (4): F667–F674. doi:10.1152/ajprenal.2001.280.4.F667. PMID11249858.
Standal T, Borset M, Sundan A (September 2004). “Role of osteopontin in adhesion, migration, cell survival and bone remodeling”. Experimental Oncology26 (3): 179–184. PMID15494684.
Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R (September 2006). “Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death”. Journal of Cellular Physiology208 (3): 629–639. doi:10.1002/jcp.20701. PMID16741956.
Fisher LW, Fedarko NS (2003). “Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins”. Connective Tissue Research44 (Suppl 1): 33–40. doi:10.1080/03008200390152061. PMID12952171.
Addison WN, Nakano Y, Loisel T, Crine P, McKee MD (October 2008). “MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM”. Journal of Bone and Mineral Research23 (10): 1638–1649. doi:10.1359/jbmr.080601. PMID18597632.
Addison WN, Masica DL, Gray JJ, McKee MD (April 2010). “Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage”. Journal of Bone and Mineral Research25 (4): 695–705. doi:10.1359/jbmr.090832. PMID19775205.
Hunter GK, O'Young J, Grohe B, Karttunen M, Goldberg HA (December 2010). “The flexible polyelectrolyte hypothesis of protein-biomineral interaction”. Langmuir26 (24): 18639–18646. doi:10.1021/la100401r. PMID20527831.
McKee MD, Nanci A (May 1995). “Postembedding colloidal-gold immunocytochemistry of noncollagenous extracellular matrix proteins in mineralized tissues”. Microscopy Research and Technique31 (1): 44–62. doi:10.1002/jemt.1070310105. PMID7626799.
Takemura T, Sakagami M, Nakase T, Kubo T, Kitamura Y, Nomura S (September 1994). “Localization of osteopontin in the otoconial organs of adult rats”. Hearing Research79 (1–2): 99–104. doi:10.1016/0378-5955(94)90131-7. PMID7806488.
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