Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K. Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metab. 2016 Aug 9;24(2):256-68. doi:10.1016/j.cmet.2016.07.010. Epub 2016 Jul 27. PMID27475046.
Soto-Mota A, Vansant H, Evans RD, Clarke K. Safety and tolerability of sustained exogenous ketosis using ketone monoester drinks for 28 days in healthy adults. Regul Toxicol Pharmacol. 2019 Dec;109:104506. doi:10.1016/j.yrtph.2019.104506. Epub 2019 Oct 23. PMID31655093.
Han YM, Ramprasath T, Zou MH. β-hydroxybutyrate and its metabolic effects on age-associated pathology. Exp Mol Med. 2020 Apr;52(4):548-555. doi:10.1038/s12276-020-0415-z. Epub 2020 Apr 8. PMID32269287; PMC7210293.
D, Avgerinos KI. Brain glucose and ketone utilization in brain aging and neurodegenerative diseases. Int Rev Neurobiol. 2020;154:79-110. doi:10.1016/bs.irn.2020.03.015. Epub 2020 Jul 10. PMID32739015.
Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans. Med Sci Sports Exerc. 2017 Sep;49(9):1789-1795. doi:10.1249/MSS.0000000000001292. PMID28398950; PMC5556006.
Clarke K, Tchabanenko K, Pawlosky R, Carter E, Todd King M, Musa-Veloso K, Ho M, Roberts A, Robertson J, Vanitallie TB, Veech RL. Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects. Regul Toxicol Pharmacol. 2012 Aug;63(3):401-8. doi:10.1016/j.yrtph.2012.04.008. Epub 2012 May 3. PMID22561291; PMC3810007.
Murray AJ, Knight NS, Cole MA, Cochlin LE, Carter E, Tchabanenko K, Pichulik T, Gulston MK, Atherton HJ, Schroeder MA, Deacon RM, Kashiwaya Y, King MT, Pawlosky R, Rawlins JN, Tyler DJ, Griffin JL, Robertson J, Veech RL, Clarke K. Novel ketone diet enhances physical and cognitive performance. FASEB J. 2016 Dec;30(12):4021-4032. doi:10.1096/fj.201600773R. Epub 2016 Aug 15. PMID27528626; PMC5102124.
Poff AM, Ari C, Arnold P, Seyfried TN, D'Agostino DP. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int J Cancer. 2014 Oct 1;135(7):1711-20. doi:10.1002/ijc.28809. Epub 2014 May 14. PMID24615175; PMC4235292.
Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure. Circ Heart Fail. 2020 Dec 28:CIRCHEARTFAILURE120007684. doi:10.1161/CIRCHEARTFAILURE.120.007684. Epub ahead of print. PMID33356362.
nih.gov
pubmed.ncbi.nlm.nih.gov
Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K. Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metab. 2016 Aug 9;24(2):256-68. doi:10.1016/j.cmet.2016.07.010. Epub 2016 Jul 27. PMID27475046.
Soto-Mota A, Vansant H, Evans RD, Clarke K. Safety and tolerability of sustained exogenous ketosis using ketone monoester drinks for 28 days in healthy adults. Regul Toxicol Pharmacol. 2019 Dec;109:104506. doi:10.1016/j.yrtph.2019.104506. Epub 2019 Oct 23. PMID31655093.
Han YM, Ramprasath T, Zou MH. β-hydroxybutyrate and its metabolic effects on age-associated pathology. Exp Mol Med. 2020 Apr;52(4):548-555. doi:10.1038/s12276-020-0415-z. Epub 2020 Apr 8. PMID32269287; PMC7210293.
D, Avgerinos KI. Brain glucose and ketone utilization in brain aging and neurodegenerative diseases. Int Rev Neurobiol. 2020;154:79-110. doi:10.1016/bs.irn.2020.03.015. Epub 2020 Jul 10. PMID32739015.
Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans. Med Sci Sports Exerc. 2017 Sep;49(9):1789-1795. doi:10.1249/MSS.0000000000001292. PMID28398950; PMC5556006.
Clarke K, Tchabanenko K, Pawlosky R, Carter E, Todd King M, Musa-Veloso K, Ho M, Roberts A, Robertson J, Vanitallie TB, Veech RL. Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects. Regul Toxicol Pharmacol. 2012 Aug;63(3):401-8. doi:10.1016/j.yrtph.2012.04.008. Epub 2012 May 3. PMID22561291; PMC3810007.
Murray AJ, Knight NS, Cole MA, Cochlin LE, Carter E, Tchabanenko K, Pichulik T, Gulston MK, Atherton HJ, Schroeder MA, Deacon RM, Kashiwaya Y, King MT, Pawlosky R, Rawlins JN, Tyler DJ, Griffin JL, Robertson J, Veech RL, Clarke K. Novel ketone diet enhances physical and cognitive performance. FASEB J. 2016 Dec;30(12):4021-4032. doi:10.1096/fj.201600773R. Epub 2016 Aug 15. PMID27528626; PMC5102124.
Poff AM, Ari C, Arnold P, Seyfried TN, D'Agostino DP. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int J Cancer. 2014 Oct 1;135(7):1711-20. doi:10.1002/ijc.28809. Epub 2014 May 14. PMID24615175; PMC4235292.
Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure. Circ Heart Fail. 2020 Dec 28:CIRCHEARTFAILURE120007684. doi:10.1161/CIRCHEARTFAILURE.120.007684. Epub ahead of print. PMID33356362.
ncbi.nlm.nih.gov
Han YM, Ramprasath T, Zou MH. β-hydroxybutyrate and its metabolic effects on age-associated pathology. Exp Mol Med. 2020 Apr;52(4):548-555. doi:10.1038/s12276-020-0415-z. Epub 2020 Apr 8. PMID32269287; PMC7210293.
Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans. Med Sci Sports Exerc. 2017 Sep;49(9):1789-1795. doi:10.1249/MSS.0000000000001292. PMID28398950; PMC5556006.
Clarke K, Tchabanenko K, Pawlosky R, Carter E, Todd King M, Musa-Veloso K, Ho M, Roberts A, Robertson J, Vanitallie TB, Veech RL. Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects. Regul Toxicol Pharmacol. 2012 Aug;63(3):401-8. doi:10.1016/j.yrtph.2012.04.008. Epub 2012 May 3. PMID22561291; PMC3810007.
Murray AJ, Knight NS, Cole MA, Cochlin LE, Carter E, Tchabanenko K, Pichulik T, Gulston MK, Atherton HJ, Schroeder MA, Deacon RM, Kashiwaya Y, King MT, Pawlosky R, Rawlins JN, Tyler DJ, Griffin JL, Robertson J, Veech RL, Clarke K. Novel ketone diet enhances physical and cognitive performance. FASEB J. 2016 Dec;30(12):4021-4032. doi:10.1096/fj.201600773R. Epub 2016 Aug 15. PMID27528626; PMC5102124.
Poff AM, Ari C, Arnold P, Seyfried TN, D'Agostino DP. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int J Cancer. 2014 Oct 1;135(7):1711-20. doi:10.1002/ijc.28809. Epub 2014 May 14. PMID24615175; PMC4235292.