シグナル伝達兼転写活性化因子1 (Japanese Wikipedia)

Analysis of information sources in references of the Wikipedia article "シグナル伝達兼転写活性化因子1" in Japanese language version.

refsWebsite

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64nih.gov

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41doi.org

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4harvard.edu

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2ensembl.org

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2wikipedia.org

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1genecards.org

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1uniprot.org

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1books.google.com

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1asid.ma

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asid.ma

“Defects of STAT1 in Human. Loss of Function exposes to Mycobacteria. Gain of Function exposes to Candida”. www.asid.ma-gb. 2017年6月1日閲覧。

books.google.com

Rezaei, Nima; Aghamohammadi, Asghar; Notarangelo, Luigi D. (2016-11-30). Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management. Springer. ISBN 9783662529096

doi.org

Safa Baris, Fayhan Alroqi, Ayca Kiykim, Elif Karakoc-Aydiner, Ismail Ogulur, Ahmet Ozen, Louis-Marie Charbonnier, Mustafa Bakır, Kaan Boztug, Talal A. Chatila & Isil B. Barlan (2016-7-5). “Severe Early-Onset Combined Immunodeficiency due to Heterozygous Gain-of-Function Mutations in STAT1”. Journal of Clinical Immunology 36 (7): 641–8. doi:10.1007/s10875-016-0312-3. PMC 5556363. PMID 27379765.
Fanny Baran-Marszak, Jean Feuillard, Imen Najjar, Christophe Le Clorennec, Jean-Marie Béchet, Isabelle Dusanter-Fourt, Georg W Bornkamm, Martine Raphaël, Remi Fagard (2004-08-15). “Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells”. Blood 104 (8): 2475–83. doi:10.1182/blood-2003-10-3508. PMID 15217838.
Ying Zhang, Yelong Chen, Hailong Yun, Zhaoyong Liu, Min Su 1, Raymond Lai (2017-08-05). “STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma”. Cell Death & Disease 8 (10): e3077. doi:10.1038/cddis.2017.481. PMC 5682650. PMID 28981100.
Christian Semper, Nicole R. Leitner, Caroline Lassnig, Matthias Parrini, Tanel Mahlakõiv, Michael Rammerstorfer, Karin Lorenz, , Doris Rigler, Simone Müller, Thomas Kolbe, Claus Vogl, Thomas Rülicke, Peter Staeheli, Thomas Decker, Mathias Müller, and Birgit StroblSHOW FEWER (2014-06-15). “STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity”. Molecular and Cellular Biology 34 (12): 2235–48. doi:10.1128/mcb.00295-14. PMC 4054301. PMID 24710278.
Michael G. Katze, Yupeng He, Michael Gale Jr. (2002-07-01). “Viruses and interferon: a fight for supremacy”. Nature Reviews. Immunology 2 (9): 675–87. doi:10.1038/nri888. PMID 12209136.
Matthieu Deschamps, Guillaume Laval, Maud Fagny, Yuval Itan, Laurent Abel, Jean-Laurent Casanova, Etienne Patin, Lluis Quintana-Murci (2016-01-07). “Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes”. American Journal of Human Genetics 98 (1): 5–21. doi:10.1016/j.ajhg.2015.11.014. PMC 4716683. PMID 26748513.
“A partial form of recessive STAT1 deficiency in humans”. The Journal of Clinical Investigation 119 (6): 1502–14. (June 2009). doi:10.1172/jci37083. PMC 2689115. PMID 19436109.
Stéphanie Dupuis, Catherine Dargemont, Claire Fieschi, Nicolas Thomassin, Sergio Rosenzweig, Jeff Harris, Steven M. Holland, Robert D. Schreiber, Jean-Laurent Casanova (2001-7-13). “Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation”. Science 293 (5528): 300-303. doi:10.1126/science.1061154. PMID 11452125.
Stéphanie Dupuis, Emmanuelle Jouanguy, Sami Al-Hajjar, Claire Fieschi, Ibrahim Zaid Al-Mohsen, Suliman Al-Jumaah, Kun Yang, Ariane Chapgier, Céline Eidenschenk, Pierre Eid, Abdulaziz Al Ghonaium, Haysam Tufenkeji, Husn Frayha, Suleiman Al-Gazlan, Hassan Al-Rayes, Robert D Schreiber, Ion Gresser, Jean-Laurent Casanova. “Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency”. Nature Genetics 33 (3): 388-91. doi:10.1038/ng1097. PMID 12590259.
International STAT1 Gain-of-Function Study Group (2016-6-23). “Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype”. Blood 127 (25): 3154–64. doi:10.1182/blood-2015-11-679902. PMC 4920021. PMID 27114460.
Stéphanie Dupuis, Emmanuelle Jouanguy, Sami Al-Hajjar, Claire Fieschi, Ibrahim Zaid Al-Mohsen, Suliman Al-Jumaah, Kun Yang, Ariane Chapgier, Céline Eidenschenk, Pierre Eid, Abdulaziz Al Ghonaium, Haysam Tufenkeji, Husn Frayha, Suleiman Al-Gazlan, Hassan Al-Rayes, Robert D Schreiber, Ion Gresser, Jean-Laurent Casanova (March 2003). “Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency”. Nature Genetics 33 (3): 388–91. doi:10.1038/ng1097. PMID 12590259.
Toru Ouchi, Sam W. Lee, Mutsuko Ouchi, Stuart A. Aaronson, and Curt M. Horvath (2000-05-09). “Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5208–13. Bibcode: 2000PNAS...97.5208O. doi:10.1073/pnas.080469697. PMC 25807. PMID 10792030.
Xiaokui Zhang, Melissa H. Wrzeszczynska, Curt M. Horvath, and James E. Darnell Jr. (1999-10-01). “Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation”. Molecular and Cellular Biology 19 (10): 7138–46. doi:10.1128/MCB.19.10.7138. PMC 84707. PMID 10490649.
Candy DeBerry, Sherry Mou, Diana Linnekin (October 1997). “Stat1 associates with c-kit and is activated in response to stem cell factor”. The Biochemical Journal 327 (1): 73–80. doi:10.1042/bj3270073. PMC 1218765. PMID 9355737.
Jue J. Zhang, Uwe Vinkemeier, Wei Gu, Debabrata Chakravarti, Curt M. Horvath, and James E. Darnell Jr. (1996-12-24). “Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling”. Proceedings of the National Academy of Sciences of the United States of America 93 (26): 15092–6. Bibcode: 1996PNAS...9315092Z. doi:10.1073/pnas.93.26.15092. PMC 26361. PMID 8986769.
Marcos Vidal, Chilakamarti V Ramana, Adriana S Dusso (April 2002). “Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription”. Molecular and Cellular Biology 22 (8): 2777–87. doi:10.1128/mcb.22.8.2777-2787.2002. PMC 133712. PMID 11909970.
Monilola A. Olayioye, Iwan Beuvink, Kay Horsch, John M. Daly, Nancy E. Hynes (June 1999). “ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases”. The Journal of Biological Chemistry 274 (24): 17209–18. doi:10.1074/jbc.274.24.17209. PMID 10358079.
Ling Xia, Lijuan Wang, Alicia S Chung, Stanimir S Ivanov, Mike Y Ling, Ana M Dragoi, Adam Platt, Tona M Gilmer, Xin-Yuan Fu, Y Eugene Chin (2002-08-23). “Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation”. The Journal of Biological Chemistry 277 (34): 30716–23. doi:10.1074/jbc.M202823200. PMID 12070153.
Qishen Pang, Sara Fagerlie, Tracy A. Christianson, Winifred Keeble, Greg Faulkner, Jane Diaz, R. Keaney Rathbun, and Grover C. Bagby (2000-07-01). “The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors”. Molecular and Cellular Biology 20 (13): 4724–35. doi:10.1128/mcb.20.13.4724-4735.2000. PMC 85895. PMID 10848598.
Tanja Y. Reuter, Annette L. Medhurst, Quinten Waisfisz, Yu Zhi, Sabine Herterich, Holger Hoehn, Hans J. Gross, Hans Joenje, Maureen E. Hoatlin, Christopher G. Mathew, Pia A. J. Huber (2003-08-01). “Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport”. Experimental Cell Research 289 (2): 211–21. doi:10.1016/s0014-4827(03)00261-1. PMID 14499622.
Qishen Pang, Tracy A. Christianson, Winifred Keeble, Jane Diaz, Gregory R. Faulkner, Carol Reifsteck, Susan Olson, Grover C. Bagby (2001-09-01). “The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality”. Blood 98 (5): 1392–401. doi:10.1182/blood.v98.5.1392. PMID 11520787.
A Usacheva, R Smith, R Minshall, G Baida, S Seng, E Croze, O Colamonici (June 2001). “The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor”. The Journal of Biological Chemistry 276 (25): 22948–53. doi:10.1074/jbc.M100087200. PMID 11301323.
Anna Usacheva, Xinyong Tian, Raudel Sandoval, Debra Salvi, David Levy and Oscar R. Colamonici (2003-09-15). “The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex”. Journal of Immunology 171 (6): 2989–94. doi:10.4049/jimmunol.171.6.2989. PMID 12960323.
X Li, S Leung, I M Kerr, and G R Stark (April 1997). “Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling”. Molecular and Cellular Biology 17 (4): 2048–56. doi:10.1128/mcb.17.4.2048. PMC 232052. PMID 9121453.
Moitreyee Chatterjee-Kishore, Focco van den Akker, George R. Stark (2000-07-07). “Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1”. The Journal of Biological Chemistry 275 (27): 20406–11. doi:10.1074/jbc.M001861200. PMID 10764778.
C M Horvath, G R Stark, I M Kerr, and J E Darnell, Jr (December 1996). “Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex”. Molecular and Cellular Biology 16 (12): 6957–64. doi:10.1128/mcb.16.12.6957. PMC 231699. PMID 8943351.
Atsunobu Takeda, Shinjiro Hamano, Atsushi Yamanaka, Toshikatsu Hanada, Tatsuro Ishibashi, Tak W Mak, Akihiko Yoshimura, Hiroki Yoshida (2003-05-15). “Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment”. Journal of Immunology 170 (10): 4886–90. doi:10.4049/jimmunol.170.10.4886. PMID 12734330.
Jue J. Zhang, Yingming Zhao, Brian T. Chait, Wyndham W. Lathem, Marion Ritzi, Rolf Knippers, James E. Darnell Jr (1998-12-01). “Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation”. The EMBO Journal 17 (23): 6963–71. doi:10.1093/emboj/17.23.6963. PMC 1171044. PMID 9843502.
Christopher J. DaFonseca, Fong Shu, and J. Jillian Zhang (2001-03-13). “Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma”. Proceedings of the National Academy of Sciences of the United States of America 98 (6): 3034–9. Bibcode: 2001PNAS...98.3034D. doi:10.1073/pnas.061487598. PMC 30602. PMID 11248027.
Arnold S Kristof, Joanna Marks-Konczalik, Eric Billings, Joel Moss (2003-09-05). “Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin”. The Journal of Biological Chemistry 278 (36): 33637–44. doi:10.1074/jbc.M301053200. PMID 12807916.
Jiayu Liao, Yubin Fu, and Ke Shuai (2000-05-09). “Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5267–72. Bibcode: 2000PNAS...97.5267L. doi:10.1073/pnas.97.10.5267. PMC 25817. PMID 10805787.
B Xie, J Zhao, M Kitagawa, J Durbin, J A Madri, J L Guan, X Y Fu (2001-06-01). “Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion”. The Journal of Biological Chemistry 276 (22): 19512–23. doi:10.1074/jbc.M009063200. PMID 11278462.
Andrew Hoi-Tao Wong, Nancy Wai Ning Tam, Yi-Li Yang, Andrew R. Cuddihy, Suiyang Li, Sabine Kirchhoff, Hansjörg Hauser, Thomas Decker, Antonis E. Koromilas (1997-03-15). “Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways”. The EMBO Journal 16 (6): 1291–304. doi:10.1093/emboj/16.6.1291. PMC 1169727. PMID 9135145.
Andrew Hoi-Tao Wong, Joan E. Durbin, Suiyang Li, Thomas E. Dever, Thomas Decker (2001-04-27). “Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR”. The Journal of Biological Chemistry 276 (17): 13727–37. doi:10.1074/jbc.M011240200. PMID 11278865.
Xiaoxia Li, Stewart Leung, Sajjad Qureshi, James E. Darnell Jr. George R. Stark (1996-03-08). “Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha”. The Journal of Biological Chemistry 271 (10): 5790–4. doi:10.1074/jbc.271.10.5790. PMID 8621447.
Inna Dumler, Angela Kopmann, Kai Wagner, Rainer Dietz, Hermann Haller, Dietrich C. Gulba (1999-08-20). “Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells”. The Journal of Biological Chemistry 274 (34): 24059–65. doi:10.1074/jbc.274.34.24059. PMID 10446176.
Riku Fagerlund, Krister Mélen, Leena Kinnunen, Ilkka Julkunen (2002-08-16). “Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5”. The Journal of Biological Chemistry 277 (33): 30072–8. doi:10.1074/jbc.M202943200. PMID 12048190.
Jagadambika J. Gunaje, G. Jayarama Bhat (2001-10-19). “Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin”. Biochemical and Biophysical Research Communications 288 (1): 252–7. doi:10.1006/bbrc.2001.5759. PMID 11594781.
K Spiekermann, S Biethahn, S Wilde, W Hiddemann, F Alves (2001-08). “Constitutive activation of STAT transcription factors in acute myelogenous leukemia”. European Journal of Haematology 67 (2): 63–71. doi:10.1034/j.1600-0609.2001.t01-1-00385.x. PMID 11722592.
Paolo Cirri, Paola Chiarugi, Fabio Marra, Giovanni Raugei, Guido Camici, Giampaolo Manao, Giampietro Ramponi (1997-10-20). “c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells”. Biochemical and Biophysical Research Communications 239 (2): 493–7. doi:10.1006/bbrc.1997.7493. PMID 9344858.
Yingjian Wang, Tong R. Wu, Shiying Cai, Thomas Welte, and Y. Eugene Chin (2000-07-01). “Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation”. Molecular and Cellular Biology 20 (13): 4505–12. doi:10.1128/mcb.20.13.4505-4512.2000. PMC 85828. PMID 10848577.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000115415 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000026104 - Ensembl, May 2017

genecards.org

GeneCards. “IRF9 Gene (Protein Coding) Interferon Regulatory Factor 9” (英語). www.genecards.org. GeneCards – the human gene database. 2017年6月1日閲覧。

harvard.edu

ui.adsabs.harvard.edu

Toru Ouchi, Sam W. Lee, Mutsuko Ouchi, Stuart A. Aaronson, and Curt M. Horvath (2000-05-09). “Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5208–13. Bibcode: 2000PNAS...97.5208O. doi:10.1073/pnas.080469697. PMC 25807. PMID 10792030.
Jue J. Zhang, Uwe Vinkemeier, Wei Gu, Debabrata Chakravarti, Curt M. Horvath, and James E. Darnell Jr. (1996-12-24). “Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling”. Proceedings of the National Academy of Sciences of the United States of America 93 (26): 15092–6. Bibcode: 1996PNAS...9315092Z. doi:10.1073/pnas.93.26.15092. PMC 26361. PMID 8986769.
Christopher J. DaFonseca, Fong Shu, and J. Jillian Zhang (2001-03-13). “Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma”. Proceedings of the National Academy of Sciences of the United States of America 98 (6): 3034–9. Bibcode: 2001PNAS...98.3034D. doi:10.1073/pnas.061487598. PMC 30602. PMID 11248027.
Jiayu Liao, Yubin Fu, and Ke Shuai (2000-05-09). “Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5267–72. Bibcode: 2000PNAS...97.5267L. doi:10.1073/pnas.97.10.5267. PMC 25817. PMID 10805787.

nih.gov

pubmed.ncbi.nlm.nih.gov

Safa Baris, Fayhan Alroqi, Ayca Kiykim, Elif Karakoc-Aydiner, Ismail Ogulur, Ahmet Ozen, Louis-Marie Charbonnier, Mustafa Bakır, Kaan Boztug, Talal A. Chatila & Isil B. Barlan (2016-7-5). “Severe Early-Onset Combined Immunodeficiency due to Heterozygous Gain-of-Function Mutations in STAT1”. Journal of Clinical Immunology 36 (7): 641–8. doi:10.1007/s10875-016-0312-3. PMC 5556363. PMID 27379765.
Fanny Baran-Marszak, Jean Feuillard, Imen Najjar, Christophe Le Clorennec, Jean-Marie Béchet, Isabelle Dusanter-Fourt, Georg W Bornkamm, Martine Raphaël, Remi Fagard (2004-08-15). “Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells”. Blood 104 (8): 2475–83. doi:10.1182/blood-2003-10-3508. PMID 15217838.
Ying Zhang, Yelong Chen, Hailong Yun, Zhaoyong Liu, Min Su 1, Raymond Lai (2017-08-05). “STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma”. Cell Death & Disease 8 (10): e3077. doi:10.1038/cddis.2017.481. PMC 5682650. PMID 28981100.
Christian Semper, Nicole R. Leitner, Caroline Lassnig, Matthias Parrini, Tanel Mahlakõiv, Michael Rammerstorfer, Karin Lorenz, , Doris Rigler, Simone Müller, Thomas Kolbe, Claus Vogl, Thomas Rülicke, Peter Staeheli, Thomas Decker, Mathias Müller, and Birgit StroblSHOW FEWER (2014-06-15). “STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity”. Molecular and Cellular Biology 34 (12): 2235–48. doi:10.1128/mcb.00295-14. PMC 4054301. PMID 24710278.
Michael G. Katze, Yupeng He, Michael Gale Jr. (2002-07-01). “Viruses and interferon: a fight for supremacy”. Nature Reviews. Immunology 2 (9): 675–87. doi:10.1038/nri888. PMID 12209136.
“Diallyl disulfide induced signal transducer and activator of transcription 1 expression in human colon cancer colo 205 cells using differential display RT-PCR”. Cancer Genomics & Proteomics 4 (2): 93–7. (2007). PMID 17804871.
Matthieu Deschamps, Guillaume Laval, Maud Fagny, Yuval Itan, Laurent Abel, Jean-Laurent Casanova, Etienne Patin, Lluis Quintana-Murci (2016-01-07). “Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes”. American Journal of Human Genetics 98 (1): 5–21. doi:10.1016/j.ajhg.2015.11.014. PMC 4716683. PMID 26748513.
“A partial form of recessive STAT1 deficiency in humans”. The Journal of Clinical Investigation 119 (6): 1502–14. (June 2009). doi:10.1172/jci37083. PMC 2689115. PMID 19436109.
Stéphanie Dupuis, Catherine Dargemont, Claire Fieschi, Nicolas Thomassin, Sergio Rosenzweig, Jeff Harris, Steven M. Holland, Robert D. Schreiber, Jean-Laurent Casanova (2001-7-13). “Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation”. Science 293 (5528): 300-303. doi:10.1126/science.1061154. PMID 11452125.
Stéphanie Dupuis, Emmanuelle Jouanguy, Sami Al-Hajjar, Claire Fieschi, Ibrahim Zaid Al-Mohsen, Suliman Al-Jumaah, Kun Yang, Ariane Chapgier, Céline Eidenschenk, Pierre Eid, Abdulaziz Al Ghonaium, Haysam Tufenkeji, Husn Frayha, Suleiman Al-Gazlan, Hassan Al-Rayes, Robert D Schreiber, Ion Gresser, Jean-Laurent Casanova. “Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency”. Nature Genetics 33 (3): 388-91. doi:10.1038/ng1097. PMID 12590259.
International STAT1 Gain-of-Function Study Group (2016-6-23). “Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype”. Blood 127 (25): 3154–64. doi:10.1182/blood-2015-11-679902. PMC 4920021. PMID 27114460.
Stéphanie Dupuis, Emmanuelle Jouanguy, Sami Al-Hajjar, Claire Fieschi, Ibrahim Zaid Al-Mohsen, Suliman Al-Jumaah, Kun Yang, Ariane Chapgier, Céline Eidenschenk, Pierre Eid, Abdulaziz Al Ghonaium, Haysam Tufenkeji, Husn Frayha, Suleiman Al-Gazlan, Hassan Al-Rayes, Robert D Schreiber, Ion Gresser, Jean-Laurent Casanova (March 2003). “Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency”. Nature Genetics 33 (3): 388–91. doi:10.1038/ng1097. PMID 12590259.
Toru Ouchi, Sam W. Lee, Mutsuko Ouchi, Stuart A. Aaronson, and Curt M. Horvath (2000-05-09). “Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5208–13. Bibcode: 2000PNAS...97.5208O. doi:10.1073/pnas.080469697. PMC 25807. PMID 10792030.
Xiaokui Zhang, Melissa H. Wrzeszczynska, Curt M. Horvath, and James E. Darnell Jr. (1999-10-01). “Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation”. Molecular and Cellular Biology 19 (10): 7138–46. doi:10.1128/MCB.19.10.7138. PMC 84707. PMID 10490649.
Candy DeBerry, Sherry Mou, Diana Linnekin (October 1997). “Stat1 associates with c-kit and is activated in response to stem cell factor”. The Biochemical Journal 327 (1): 73–80. doi:10.1042/bj3270073. PMC 1218765. PMID 9355737.
Jue J. Zhang, Uwe Vinkemeier, Wei Gu, Debabrata Chakravarti, Curt M. Horvath, and James E. Darnell Jr. (1996-12-24). “Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling”. Proceedings of the National Academy of Sciences of the United States of America 93 (26): 15092–6. Bibcode: 1996PNAS...9315092Z. doi:10.1073/pnas.93.26.15092. PMC 26361. PMID 8986769.
Marcos Vidal, Chilakamarti V Ramana, Adriana S Dusso (April 2002). “Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription”. Molecular and Cellular Biology 22 (8): 2777–87. doi:10.1128/mcb.22.8.2777-2787.2002. PMC 133712. PMID 11909970.
Monilola A. Olayioye, Iwan Beuvink, Kay Horsch, John M. Daly, Nancy E. Hynes (June 1999). “ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases”. The Journal of Biological Chemistry 274 (24): 17209–18. doi:10.1074/jbc.274.24.17209. PMID 10358079.
Ling Xia, Lijuan Wang, Alicia S Chung, Stanimir S Ivanov, Mike Y Ling, Ana M Dragoi, Adam Platt, Tona M Gilmer, Xin-Yuan Fu, Y Eugene Chin (2002-08-23). “Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation”. The Journal of Biological Chemistry 277 (34): 30716–23. doi:10.1074/jbc.M202823200. PMID 12070153.
Qishen Pang, Sara Fagerlie, Tracy A. Christianson, Winifred Keeble, Greg Faulkner, Jane Diaz, R. Keaney Rathbun, and Grover C. Bagby (2000-07-01). “The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors”. Molecular and Cellular Biology 20 (13): 4724–35. doi:10.1128/mcb.20.13.4724-4735.2000. PMC 85895. PMID 10848598.
Tanja Y. Reuter, Annette L. Medhurst, Quinten Waisfisz, Yu Zhi, Sabine Herterich, Holger Hoehn, Hans J. Gross, Hans Joenje, Maureen E. Hoatlin, Christopher G. Mathew, Pia A. J. Huber (2003-08-01). “Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport”. Experimental Cell Research 289 (2): 211–21. doi:10.1016/s0014-4827(03)00261-1. PMID 14499622.
Qishen Pang, Tracy A. Christianson, Winifred Keeble, Jane Diaz, Gregory R. Faulkner, Carol Reifsteck, Susan Olson, Grover C. Bagby (2001-09-01). “The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality”. Blood 98 (5): 1392–401. doi:10.1182/blood.v98.5.1392. PMID 11520787.
A Usacheva, R Smith, R Minshall, G Baida, S Seng, E Croze, O Colamonici (June 2001). “The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor”. The Journal of Biological Chemistry 276 (25): 22948–53. doi:10.1074/jbc.M100087200. PMID 11301323.
Anna Usacheva, Xinyong Tian, Raudel Sandoval, Debra Salvi, David Levy and Oscar R. Colamonici (2003-09-15). “The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex”. Journal of Immunology 171 (6): 2989–94. doi:10.4049/jimmunol.171.6.2989. PMID 12960323.
X Li, S Leung, I M Kerr, and G R Stark (April 1997). “Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling”. Molecular and Cellular Biology 17 (4): 2048–56. doi:10.1128/mcb.17.4.2048. PMC 232052. PMID 9121453.
Moitreyee Chatterjee-Kishore, Focco van den Akker, George R. Stark (2000-07-07). “Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1”. The Journal of Biological Chemistry 275 (27): 20406–11. doi:10.1074/jbc.M001861200. PMID 10764778.
C M Horvath, G R Stark, I M Kerr, and J E Darnell, Jr (December 1996). “Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex”. Molecular and Cellular Biology 16 (12): 6957–64. doi:10.1128/mcb.16.12.6957. PMC 231699. PMID 8943351.
Atsunobu Takeda, Shinjiro Hamano, Atsushi Yamanaka, Toshikatsu Hanada, Tatsuro Ishibashi, Tak W Mak, Akihiko Yoshimura, Hiroki Yoshida (2003-05-15). “Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment”. Journal of Immunology 170 (10): 4886–90. doi:10.4049/jimmunol.170.10.4886. PMID 12734330.
Jue J. Zhang, Yingming Zhao, Brian T. Chait, Wyndham W. Lathem, Marion Ritzi, Rolf Knippers, James E. Darnell Jr (1998-12-01). “Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation”. The EMBO Journal 17 (23): 6963–71. doi:10.1093/emboj/17.23.6963. PMC 1171044. PMID 9843502.
Christopher J. DaFonseca, Fong Shu, and J. Jillian Zhang (2001-03-13). “Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma”. Proceedings of the National Academy of Sciences of the United States of America 98 (6): 3034–9. Bibcode: 2001PNAS...98.3034D. doi:10.1073/pnas.061487598. PMC 30602. PMID 11248027.
Arnold S Kristof, Joanna Marks-Konczalik, Eric Billings, Joel Moss (2003-09-05). “Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin”. The Journal of Biological Chemistry 278 (36): 33637–44. doi:10.1074/jbc.M301053200. PMID 12807916.
Jiayu Liao, Yubin Fu, and Ke Shuai (2000-05-09). “Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5267–72. Bibcode: 2000PNAS...97.5267L. doi:10.1073/pnas.97.10.5267. PMC 25817. PMID 10805787.
B Xie, J Zhao, M Kitagawa, J Durbin, J A Madri, J L Guan, X Y Fu (2001-06-01). “Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion”. The Journal of Biological Chemistry 276 (22): 19512–23. doi:10.1074/jbc.M009063200. PMID 11278462.
Andrew Hoi-Tao Wong, Nancy Wai Ning Tam, Yi-Li Yang, Andrew R. Cuddihy, Suiyang Li, Sabine Kirchhoff, Hansjörg Hauser, Thomas Decker, Antonis E. Koromilas (1997-03-15). “Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways”. The EMBO Journal 16 (6): 1291–304. doi:10.1093/emboj/16.6.1291. PMC 1169727. PMID 9135145.
Andrew Hoi-Tao Wong, Joan E. Durbin, Suiyang Li, Thomas E. Dever, Thomas Decker (2001-04-27). “Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR”. The Journal of Biological Chemistry 276 (17): 13727–37. doi:10.1074/jbc.M011240200. PMID 11278865.
Xiaoxia Li, Stewart Leung, Sajjad Qureshi, James E. Darnell Jr. George R. Stark (1996-03-08). “Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha”. The Journal of Biological Chemistry 271 (10): 5790–4. doi:10.1074/jbc.271.10.5790. PMID 8621447.
Inna Dumler, Angela Kopmann, Kai Wagner, Rainer Dietz, Hermann Haller, Dietrich C. Gulba (1999-08-20). “Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells”. The Journal of Biological Chemistry 274 (34): 24059–65. doi:10.1074/jbc.274.34.24059. PMID 10446176.
Riku Fagerlund, Krister Mélen, Leena Kinnunen, Ilkka Julkunen (2002-08-16). “Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5”. The Journal of Biological Chemistry 277 (33): 30072–8. doi:10.1074/jbc.M202943200. PMID 12048190.
Jagadambika J. Gunaje, G. Jayarama Bhat (2001-10-19). “Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin”. Biochemical and Biophysical Research Communications 288 (1): 252–7. doi:10.1006/bbrc.2001.5759. PMID 11594781.
K Spiekermann, S Biethahn, S Wilde, W Hiddemann, F Alves (2001-08). “Constitutive activation of STAT transcription factors in acute myelogenous leukemia”. European Journal of Haematology 67 (2): 63–71. doi:10.1034/j.1600-0609.2001.t01-1-00385.x. PMID 11722592.
Paolo Cirri, Paola Chiarugi, Fabio Marra, Giovanni Raugei, Guido Camici, Giampaolo Manao, Giampietro Ramponi (1997-10-20). “c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells”. Biochemical and Biophysical Research Communications 239 (2): 493–7. doi:10.1006/bbrc.1997.7493. PMID 9344858.
Yingjian Wang, Tong R. Wu, Shiying Cai, Thomas Welte, and Y. Eugene Chin (2000-07-01). “Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation”. Molecular and Cellular Biology 20 (13): 4505–12. doi:10.1128/mcb.20.13.4505-4512.2000. PMC 85828. PMID 10848577.

ncbi.nlm.nih.gov

Human PubMed Reference:
Mouse PubMed Reference:
Safa Baris, Fayhan Alroqi, Ayca Kiykim, Elif Karakoc-Aydiner, Ismail Ogulur, Ahmet Ozen, Louis-Marie Charbonnier, Mustafa Bakır, Kaan Boztug, Talal A. Chatila & Isil B. Barlan (2016-7-5). “Severe Early-Onset Combined Immunodeficiency due to Heterozygous Gain-of-Function Mutations in STAT1”. Journal of Clinical Immunology 36 (7): 641–8. doi:10.1007/s10875-016-0312-3. PMC 5556363. PMID 27379765.
“STAT1 signal transducer and activator of transcription 1 [Homo sapiens (human) - Gene - NCBI]” (英語). www.ncbi.nlm.nih.gov. アメリカ国立生物工学情報センター (2021年6月9日). 2021年8月23日閲覧。
Ying Zhang, Yelong Chen, Hailong Yun, Zhaoyong Liu, Min Su 1, Raymond Lai (2017-08-05). “STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma”. Cell Death & Disease 8 (10): e3077. doi:10.1038/cddis.2017.481. PMC 5682650. PMID 28981100.
Christian Semper, Nicole R. Leitner, Caroline Lassnig, Matthias Parrini, Tanel Mahlakõiv, Michael Rammerstorfer, Karin Lorenz, , Doris Rigler, Simone Müller, Thomas Kolbe, Claus Vogl, Thomas Rülicke, Peter Staeheli, Thomas Decker, Mathias Müller, and Birgit StroblSHOW FEWER (2014-06-15). “STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity”. Molecular and Cellular Biology 34 (12): 2235–48. doi:10.1128/mcb.00295-14. PMC 4054301. PMID 24710278.
Matthieu Deschamps, Guillaume Laval, Maud Fagny, Yuval Itan, Laurent Abel, Jean-Laurent Casanova, Etienne Patin, Lluis Quintana-Murci (2016-01-07). “Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes”. American Journal of Human Genetics 98 (1): 5–21. doi:10.1016/j.ajhg.2015.11.014. PMC 4716683. PMID 26748513.
“A partial form of recessive STAT1 deficiency in humans”. The Journal of Clinical Investigation 119 (6): 1502–14. (June 2009). doi:10.1172/jci37083. PMC 2689115. PMID 19436109.
International STAT1 Gain-of-Function Study Group (2016-6-23). “Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype”. Blood 127 (25): 3154–64. doi:10.1182/blood-2015-11-679902. PMC 4920021. PMID 27114460.
Toru Ouchi, Sam W. Lee, Mutsuko Ouchi, Stuart A. Aaronson, and Curt M. Horvath (2000-05-09). “Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5208–13. Bibcode: 2000PNAS...97.5208O. doi:10.1073/pnas.080469697. PMC 25807. PMID 10792030.
Xiaokui Zhang, Melissa H. Wrzeszczynska, Curt M. Horvath, and James E. Darnell Jr. (1999-10-01). “Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation”. Molecular and Cellular Biology 19 (10): 7138–46. doi:10.1128/MCB.19.10.7138. PMC 84707. PMID 10490649.
Candy DeBerry, Sherry Mou, Diana Linnekin (October 1997). “Stat1 associates with c-kit and is activated in response to stem cell factor”. The Biochemical Journal 327 (1): 73–80. doi:10.1042/bj3270073. PMC 1218765. PMID 9355737.
Jue J. Zhang, Uwe Vinkemeier, Wei Gu, Debabrata Chakravarti, Curt M. Horvath, and James E. Darnell Jr. (1996-12-24). “Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling”. Proceedings of the National Academy of Sciences of the United States of America 93 (26): 15092–6. Bibcode: 1996PNAS...9315092Z. doi:10.1073/pnas.93.26.15092. PMC 26361. PMID 8986769.
Marcos Vidal, Chilakamarti V Ramana, Adriana S Dusso (April 2002). “Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription”. Molecular and Cellular Biology 22 (8): 2777–87. doi:10.1128/mcb.22.8.2777-2787.2002. PMC 133712. PMID 11909970.
Qishen Pang, Sara Fagerlie, Tracy A. Christianson, Winifred Keeble, Greg Faulkner, Jane Diaz, R. Keaney Rathbun, and Grover C. Bagby (2000-07-01). “The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors”. Molecular and Cellular Biology 20 (13): 4724–35. doi:10.1128/mcb.20.13.4724-4735.2000. PMC 85895. PMID 10848598.
X Li, S Leung, I M Kerr, and G R Stark (April 1997). “Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling”. Molecular and Cellular Biology 17 (4): 2048–56. doi:10.1128/mcb.17.4.2048. PMC 232052. PMID 9121453.
C M Horvath, G R Stark, I M Kerr, and J E Darnell, Jr (December 1996). “Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex”. Molecular and Cellular Biology 16 (12): 6957–64. doi:10.1128/mcb.16.12.6957. PMC 231699. PMID 8943351.
Jue J. Zhang, Yingming Zhao, Brian T. Chait, Wyndham W. Lathem, Marion Ritzi, Rolf Knippers, James E. Darnell Jr (1998-12-01). “Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation”. The EMBO Journal 17 (23): 6963–71. doi:10.1093/emboj/17.23.6963. PMC 1171044. PMID 9843502.
Christopher J. DaFonseca, Fong Shu, and J. Jillian Zhang (2001-03-13). “Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma”. Proceedings of the National Academy of Sciences of the United States of America 98 (6): 3034–9. Bibcode: 2001PNAS...98.3034D. doi:10.1073/pnas.061487598. PMC 30602. PMID 11248027.
Jiayu Liao, Yubin Fu, and Ke Shuai (2000-05-09). “Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction”. Proceedings of the National Academy of Sciences of the United States of America 97 (10): 5267–72. Bibcode: 2000PNAS...97.5267L. doi:10.1073/pnas.97.10.5267. PMC 25817. PMID 10805787.
Andrew Hoi-Tao Wong, Nancy Wai Ning Tam, Yi-Li Yang, Andrew R. Cuddihy, Suiyang Li, Sabine Kirchhoff, Hansjörg Hauser, Thomas Decker, Antonis E. Koromilas (1997-03-15). “Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways”. The EMBO Journal 16 (6): 1291–304. doi:10.1093/emboj/16.6.1291. PMC 1169727. PMID 9135145.
Yingjian Wang, Tong R. Wu, Shiying Cai, Thomas Welte, and Y. Eugene Chin (2000-07-01). “Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation”. Molecular and Cellular Biology 20 (13): 4505–12. doi:10.1128/mcb.20.13.4505-4512.2000. PMC 85828. PMID 10848577.

uniprot.org

“STAT1 - Signal transducer and activator of transcription 1-alpha/beta - Homo sapiens (Human) - STAT1 gene & protein” (英語). www.uniprot.org. UniProt Consortium. 2017年6月1日閲覧。

wikipedia.org

en.wikipedia.org

GRCh38: Ensembl release 89: ENSG00000115415 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000026104 - Ensembl, May 2017