臨床試験番号 NCT01849874 研究名 "A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer" - ClinicalTrials.gov
臨床試験番号 NCT01909453 研究名 "Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma (COLUMBUS)" - ClinicalTrials.gov
臨床試験番号 NCT01763164 研究名 "Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive Melanoma" - ClinicalTrials.gov
doi.org
“A review of binimetinib for the treatment of mutant cutaneous melanoma”. Future Oncology13 (20): 1755-1766. (August 2017). doi:10.2217/fon-2017-0170. PMID28587477.
“MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study”. The Lancet. Oncology14 (3): 249-56. (March 2013). doi:10.1016/S1470-2045(13)70024-X. PMID23414587.
“Extracellular signal-regulated kinase 1 and 2 in cancer therapy: a focus on hepatocellular carcinoma”. Molecular Biology Reports43 (2): 107-16. (February 2016). doi:10.1007/s11033-016-3943-9. PMID26767647.
“A review of binimetinib for the treatment of mutant cutaneous melanoma”. Future Oncology13 (20): 1755-1766. (August 2017). doi:10.2217/fon-2017-0170. PMID28587477.
“MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study”. The Lancet. Oncology14 (3): 249-56. (March 2013). doi:10.1016/S1470-2045(13)70024-X. PMID23414587.
“Extracellular signal-regulated kinase 1 and 2 in cancer therapy: a focus on hepatocellular carcinoma”. Molecular Biology Reports43 (2): 107-16. (February 2016). doi:10.1007/s11033-016-3943-9. PMID26767647.
臨床試験番号 NCT01849874 研究名 "A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer" - ClinicalTrials.gov
臨床試験番号 NCT01909453 研究名 "Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma (COLUMBUS)" - ClinicalTrials.gov
臨床試験番号 NCT01763164 研究名 "Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive Melanoma" - ClinicalTrials.gov