ポナチニブ (Japanese Wikipedia)

Analysis of information sources in references of the Wikipedia article "ポナチニブ" in Japanese language version.

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ariad.com

investor.ariad.com

clinicaltrials.gov

doi.org

  • “Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant”. J. Med. Chem. 53 (12): 4701–19. (June 2010). doi:10.1021/jm100395q. PMID 20513156. 
  • “AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance”. Cancer Cell 16 (5): 401–12. (November 2009). doi:10.1016/j.ccr.2009.09.028. PMC 2804470. PMID 19878872. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804470/. 
  • “Structural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance”. Chemical Biology & Drug Design 77 (1): 1–11. (January 2011). doi:10.1111/j.1747-0285.2010.01054.x. PMID 21118377. 

fda.gov

fiercebiotech.com

iclusig.com

medpagetoday.com

nih.gov

pubmed.ncbi.nlm.nih.gov

  • “Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant”. J. Med. Chem. 53 (12): 4701–19. (June 2010). doi:10.1021/jm100395q. PMID 20513156. 
  • “AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance”. Cancer Cell 16 (5): 401–12. (November 2009). doi:10.1016/j.ccr.2009.09.028. PMC 2804470. PMID 19878872. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804470/. 
  • “Structural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance”. Chemical Biology & Drug Design 77 (1): 1–11. (January 2011). doi:10.1111/j.1747-0285.2010.01054.x. PMID 21118377. 

ncbi.nlm.nih.gov

pmc.ncbi.nlm.nih.gov

nytimes.com

onclive.com

otsuka.co.jp

pmda.go.jp

info.pmda.go.jp