“Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant”. J. Med. Chem.53 (12): 4701–19. (June 2010). doi:10.1021/jm100395q. PMID20513156.
“Structural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance”. Chemical Biology & Drug Design77 (1): 1–11. (January 2011). doi:10.1111/j.1747-0285.2010.01054.x. PMID21118377.
“Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant”. J. Med. Chem.53 (12): 4701–19. (June 2010). doi:10.1021/jm100395q. PMID20513156.
“Structural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance”. Chemical Biology & Drug Design77 (1): 1–11. (January 2011). doi:10.1111/j.1747-0285.2010.01054.x. PMID21118377.