Zhu Q, et al. Novel Synthesis of Antiobesity Drug Lorcaserin Hydrochloride. Org. Process Res. Dev. 2015, 19(9): 1263–1267. doi:10.1021/acs.oprd.5b00144
“Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity”. Journal of Medicinal Chemistry51 (2): 305–13. (January 2008). doi:10.1021/jm0709034. PMID18095642.
“Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity”. Bioorganic & Medicinal Chemistry Letters15 (5): 1467–70. (March 2005). doi:10.1016/j.bmcl.2004.12.080. PMID15713408.
“Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies”. Therapie60 (5): 441–60. (2005). doi:10.2515/therapie:2005065. PMID16433010.
US patent 6953787, Brian Smith, Jeffrey Smith, "5HT2c receptor modulators", published 2003-10-04, issued 2005-11-10
US patent 7704993, Brian Smith, Charles A. Gilson, III, Jeffrey Schultz, Jeffrey Smith, "Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases", published 2004-16-06, issued 2010-27-04
US patent 8207158, Brian Smith, Jeffrey Smith, "5HT2c receptor modulators", published 2011-27-05, issued 2012-26-06
“Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity”. Journal of Medicinal Chemistry51 (2): 305–13. (January 2008). doi:10.1021/jm0709034. PMID18095642.
“Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity”. Bioorganic & Medicinal Chemistry Letters15 (5): 1467–70. (March 2005). doi:10.1016/j.bmcl.2004.12.080. PMID15713408.
“Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies”. Therapie60 (5): 441–60. (2005). doi:10.2515/therapie:2005065. PMID16433010.