小分子 (Japanese Wikipedia)

Analysis of information sources in references of the Wikipedia article "小分子" in Japanese language version.

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books.google.com

  • Macielag MJ (2012). “Chemical properties of antibacterials and their uniqueness”. Antibiotic Discovery and Development. pp. 801–2. ISBN 978-1-4614-1400-1. https://books.google.com/books?id=av5SHPiHVcsC&q=oral%20drug%20molecular%20weight%20distribution%20antibiotics&pg=PA800. "The majority of [oral] drugs from the general reference set have molecular weights below 550. In contrast the molecular-weight distribution of oral antibacterial agents is bimodal: 340–450 Da but with another group in the 700–900 molecular weight range." 
  • Samanen J (2013). “Chapter 5.2 How do SMDs differ from biomolecular drugs?”. Introduction to Biological and Small Molecule Drug Research and Development: theory and case studies (Kindle ed.). New York: Academic Press. pp. 161–203. doi:10.1016/B978-0-12-397176-0.00005-4. ISBN 978-0-12-397176-0. https://books.google.com/books?id=342JY314Fl4C&q=small+molecule+vs+biologics+oral&pg=PA187. "Table 5.13: Route of Administration: Small Molecules: oral administration usually possible; Biomolecules: Usually administered parenterally" 

doi.org

harvard.edu

ui.adsabs.harvard.edu

nih.gov

pubmed.ncbi.nlm.nih.gov

  • Arkin MR, Wells JA (April 2004). “Small-molecule inhibitors of protein-protein interactions: progressing towards the dream”. Nature Reviews Drug Discovery 3 (4): 301–17. doi:10.1038/nrd1343. PMID 15060526. 
  • Veber DF, Johnson SR, Cheng HY, Smith BR, Ward KW, Kopple KD (June 2002). “Molecular properties that influence the oral bioavailability of drug candidates”. J. Med. Chem. 45 (12): 2615–23. doi:10.1021/jm020017n. PMID 12036371. 
  • Lipinski CA (December 2004). “Lead-and drug-like compounds: the rule-of-five revolution”. Drug Discovery Today: Technologies 1 (4): 337–341. doi:10.1016/j.ddtec.2004.11.007. PMID 24981612. 
  • Leeson PD, Springthorpe B (November 2007). “The influence of drug-like concepts on decision-making in medicinal chemistry”. Nature Reviews Drug Discovery 6 (11): 881–90. doi:10.1038/nrd2445. PMID 17971784. 
  • Mfopou JK, De Groote V, Xu X, Heimberg H, Bouwens L (May 2007). “Sonic hedgehog and other soluble factors from differentiating embryoid bodies inhibit pancreas development”. Stem Cells 25 (5): 1156–65. doi:10.1634/stemcells.2006-0720. PMID 17272496. 
  • Koh JT, Zheng J (September 2007). “The new biomimetic chemistry: artificial transcription factors”. ACS Chem. Biol. 2 (9): 599–601. doi:10.1021/cb700183s. PMID 17894442. 
  • Wienken CJ, Baaske P, Rothbauer U, Braun D, Duhr S (2010). “Protein-binding assays in biological liquids using microscale thermophoresis”. Nat Commun 1 (7): 100. Bibcode2010NatCo...1..100W. doi:10.1038/ncomms1093. PMID 20981028.