臨床試験番号 NCT03158272 研究名 "A Study to of Cabiralzumab Given by Itself or With Nivolumab in Advanced Cancer or Cancer That Has Spread" - ClinicalTrials.gov
doi.org
“Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy”. Advanced Drug Delivery Reviews99 (Pt B): 180–185. (April 2016). doi:10.1016/j.addr.2015.11.009. PMID26621196.
“Macrophages and cancer: from mechanisms to therapeutic implications”. Trends in Immunology36 (4): 229–39. (April 2015). doi:10.1016/j.it.2015.02.004. PMID25770924.
“Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors”. Cancer Cell8 (3): 211–26. (September 2005). doi:10.1016/j.ccr.2005.08.002. PMID16169466.
“Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion”. Journal of Immunology186 (7): 4183–90. (April 2011). doi:10.4049/jimmunol.1002802. PMID21368233.
“Crosstalk between angiogenesis and lymphangiogenesis in tumor progression”. Leukemia18 (6): 1054–8. (June 2004). doi:10.1038/sj.leu.2403355. PMID15057248.
“The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages”. Critical Reviews in Oncology/Hematology66 (1): 1–9. (April 2008). doi:10.1016/j.critrevonc.2007.07.004. PMID17913510.
“Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages”. Nature543 (7645): 428–432. (March 2017). doi:10.1038/nature21409. PMID28273064.
nih.gov
pubmed.ncbi.nlm.nih.gov
“Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy”. Advanced Drug Delivery Reviews99 (Pt B): 180–185. (April 2016). doi:10.1016/j.addr.2015.11.009. PMID26621196.
“Macrophages and cancer: from mechanisms to therapeutic implications”. Trends in Immunology36 (4): 229–39. (April 2015). doi:10.1016/j.it.2015.02.004. PMID25770924.
“Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors”. Cancer Cell8 (3): 211–26. (September 2005). doi:10.1016/j.ccr.2005.08.002. PMID16169466.
“Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion”. Journal of Immunology186 (7): 4183–90. (April 2011). doi:10.4049/jimmunol.1002802. PMID21368233.
“Crosstalk between angiogenesis and lymphangiogenesis in tumor progression”. Leukemia18 (6): 1054–8. (June 2004). doi:10.1038/sj.leu.2403355. PMID15057248.
“The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages”. Critical Reviews in Oncology/Hematology66 (1): 1–9. (April 2008). doi:10.1016/j.critrevonc.2007.07.004. PMID17913510.
臨床試験番号 NCT03158272 研究名 "A Study to of Cabiralzumab Given by Itself or With Nivolumab in Advanced Cancer or Cancer That Has Spread" - ClinicalTrials.gov